JP2012508865A - 多発性硬化症の診断 - Google Patents

多発性硬化症の診断 Download PDF

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JP2012508865A
JP2012508865A JP2011535211A JP2011535211A JP2012508865A JP 2012508865 A JP2012508865 A JP 2012508865A JP 2011535211 A JP2011535211 A JP 2011535211A JP 2011535211 A JP2011535211 A JP 2011535211A JP 2012508865 A JP2012508865 A JP 2012508865A
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antigens
pattern
listed
reactivity
antigen
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JP2012508865A5 (zh
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ウェイナー,ハワード,エル.
コーエン,イラン,アール.
クゥインタナ,フランシスコ,ジェイ.
Original Assignee
イエダ リサーチ アンド ディベロプメント カンパニー リミテッド
ザ ブライアム アンド ウィメンズ ホスピタル,インコーポレイテッド
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Publication of JP2012508865A publication Critical patent/JP2012508865A/ja
Publication of JP2012508865A5 publication Critical patent/JP2012508865A5/ja
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/28Neurological disorders
    • G01N2800/285Demyelinating diseases; Multipel sclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Rehabilitation Therapy (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
JP2011535211A 2008-11-12 2009-11-12 多発性硬化症の診断 Pending JP2012508865A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11364508P 2008-11-12 2008-11-12
US61/113,645 2008-11-12
PCT/IL2009/001066 WO2010055510A2 (en) 2008-11-12 2009-11-12 Diagnosis of multiple sclerosis

Publications (2)

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JP2012508865A true JP2012508865A (ja) 2012-04-12
JP2012508865A5 JP2012508865A5 (zh) 2012-12-27

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JP2011535211A Pending JP2012508865A (ja) 2008-11-12 2009-11-12 多発性硬化症の診断

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US (1) US9267945B2 (zh)
EP (1) EP2353004B1 (zh)
JP (1) JP2012508865A (zh)
CN (1) CN102388307B (zh)
AU (1) AU2009315230A1 (zh)
CA (1) CA2743590A1 (zh)
HK (1) HK1168423A1 (zh)
WO (1) WO2010055510A2 (zh)

Cited By (2)

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JP2017502278A (ja) * 2013-12-12 2017-01-19 ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. 神経変性疾患の治療
US9862751B2 (en) 2013-01-15 2018-01-09 Apitope Technology (Bristol) Limited Myelin oligodendrocyte glycoprotein peptides

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US20140105980A1 (en) 2012-10-11 2014-04-17 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
US9562088B2 (en) 2010-10-19 2017-02-07 The Regents Of The University Of Colorado, A Body Corporate Pegylated CD154 peptides and methods of inhibiting CD40 interacations with CD154
US9511151B2 (en) 2010-11-12 2016-12-06 Uti Limited Partnership Compositions and methods for the prevention and treatment of cancer
US10988516B2 (en) 2012-03-26 2021-04-27 Uti Limited Partnership Methods and compositions for treating inflammation
US8652999B1 (en) 2012-07-24 2014-02-18 Dow Agrosciences, Llc. Herbicidal compositions comprising 4-amino-3-chloro-5-fluoro-6-(4-chloro-2-fluoro-3-methoxyphenyl)pyridine-2-carboxylic acid or a derivative thereof and a sulfonylaminocarbonyltriazolinone
US9603948B2 (en) 2012-10-11 2017-03-28 Uti Limited Partnership Methods and compositions for treating multiple sclerosis and related disorders
EP3065771B1 (en) 2013-11-04 2019-03-20 UTI Limited Partnership Methods and compositions for sustained immunotherapy
EP3090064B1 (en) 2013-12-31 2019-11-13 Yeda Research and Development Co. Ltd. Diagnosis of systemic lupus erythematosus using oligonucleotides antigens
US20160320384A1 (en) 2013-12-31 2016-11-03 Yeda Research And Development Co. Ltd. Methods for assaying immunological competence
US20170108514A1 (en) * 2014-03-23 2017-04-20 The Regents Of The University Of Colorado, A Body Corporate Diagnosis of multiple sclerosis in human and animal subjects
EP2927687A1 (en) * 2014-03-31 2015-10-07 Ecole Polytechnique Federale de Lausanne (EPFL) Agents useful in diagnostic and therapy of beta-amyloid aggregation related disorders and screening methods
WO2015172008A1 (en) * 2014-05-09 2015-11-12 Multiple Sclerosis Research Center Of New York Transglutaminadase 6 as a biomarker for multiple sclerosis
WO2016123565A1 (en) 2015-01-30 2016-08-04 The Regents Of The University Of California N-acetyl glucosamine as a biomarker of ms disease course
WO2016139659A1 (en) 2015-03-01 2016-09-09 Immunarray Ltd. Diagnosis of systemic lupus erythematosus using protein, peptide and oligonucleotide antigens
US12011480B2 (en) 2015-05-06 2024-06-18 Uti Limited Partnership Nanoparticle compositions for sustained therapy
CN107043413A (zh) * 2016-02-05 2017-08-15 华中农业大学 一种肺结核相关的尿液生物标志蛋白及其应用
WO2018048884A1 (en) * 2016-09-09 2018-03-15 Mayo Foundation For Medical Education And Research Methods and materials for identifying and treating autoimmune gfap astrocytopathy
BR112019009477A2 (pt) 2016-11-09 2019-07-30 Uti Lp moléculas de classe ii de pmhc recombinantes
US11793854B2 (en) 2019-03-21 2023-10-24 Op-T Llc Methods for reducing symptoms of multiple sclerosis using a six-amino acid long peptide that inhibits CD40-CD150 interaction
US12048734B2 (en) 2020-04-17 2024-07-30 Op-T Llc Bioactive peptides and methods of use thereof
CN114689865A (zh) * 2020-12-30 2022-07-01 广州市微米生物科技有限公司 视神经脊髓炎抗体检测试剂
CN113336862B (zh) * 2021-07-05 2022-03-01 广东省科学院动物研究所 一种抗多发性硬化的重组蛋白及其制备方法和用途

Citations (2)

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US20060089302A1 (en) * 2002-02-26 2006-04-27 Rivkn Abulafia-Lapid Hsp70-derived peptides and uses thereof in the diagnosis and treatment of autoimmune diseases
WO2008125651A2 (en) * 2007-04-12 2008-10-23 Apitope International Nv Biomarkers for multiple sclerosis

Family Cites Families (14)

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IL137460A0 (en) 2000-07-24 2001-07-24 Yeda Res & Dev Identifying antigen clusters for monitoring a global state of an immune system
KR100951409B1 (ko) 2001-01-09 2010-04-07 베일러 리서치 인스티튜트 수지상 세포로의 단핵세포 분화를 억제하는 조성물 및 이를 포함하는 키트
WO2002084249A2 (en) 2001-04-10 2002-10-24 The Board Of Trustees Of The Leland Stanford Junior University Therapeutic and diagnostic uses of antibody specificity profiles
US20030092089A1 (en) 2001-11-14 2003-05-15 Moscarello Mario Anthony Method for diagnosing multiple sclerosis and an assay therefore
AU2003282612A1 (en) 2002-10-11 2004-05-04 The Regents Of The University Of California A method for diagnosis and prognosis of multiple sclerosis
US20050260770A1 (en) 2004-04-01 2005-11-24 Cohen Irun R Antigen array and diagnostic uses thereof
US20080193440A1 (en) 2004-07-01 2008-08-14 Kobenhavns Universitet Method For Multiple Sclerosis Treatment and Prophylaxis By Treatment of Leptospira Infection
EP1841887A2 (en) 2005-01-19 2007-10-10 Bayer Schering Pharma Aktiengesellschaft Cx3cr1 as a marker which correlates with both disease and disease activity in multiple sclerosis patients
US7572592B2 (en) * 2005-01-31 2009-08-11 Glycominds Ltd Method for diagnosing multiple sclerosis
EP2322553A3 (en) * 2005-02-14 2011-11-16 Wyeth LLC Interleukin-17F antibodies and other IL-17F signaling antagonists and uses therefor
WO2006116155A2 (en) * 2005-04-21 2006-11-02 The Regents Of The University Of California A method for diagnosis and prognosis of multiple sclerosis subtypes
US8252775B2 (en) * 2005-07-21 2012-08-28 The Board Of Trustees Of The Leland Stanford Junior University Method of treating multiple sclerosis with phosphocholine containing lipids
WO2007056332A2 (en) 2005-11-07 2007-05-18 Vanderbilt University Molecular diagnosis of autoimmune diseases
CN101479230A (zh) 2006-05-26 2009-07-08 菲诺梅诺米发现公司 用于诊断多发性硬化的生物标记及其方法

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060089302A1 (en) * 2002-02-26 2006-04-27 Rivkn Abulafia-Lapid Hsp70-derived peptides and uses thereof in the diagnosis and treatment of autoimmune diseases
WO2008125651A2 (en) * 2007-04-12 2008-10-23 Apitope International Nv Biomarkers for multiple sclerosis

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9862751B2 (en) 2013-01-15 2018-01-09 Apitope Technology (Bristol) Limited Myelin oligodendrocyte glycoprotein peptides
US10377800B2 (en) 2013-01-15 2019-08-13 Apitope Technology (Bristol) Limited Myelin oligodendrocyte glycoprotein (MOG) peptide
JP2017502278A (ja) * 2013-12-12 2017-01-19 ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. 神経変性疾患の治療

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Publication number Publication date
CA2743590A1 (en) 2010-05-20
EP2353004A2 (en) 2011-08-10
AU2009315230A1 (en) 2010-05-20
HK1168423A1 (zh) 2012-12-28
US20120077686A1 (en) 2012-03-29
WO2010055510A3 (en) 2010-09-16
CN102388307B (zh) 2014-09-03
CN102388307A (zh) 2012-03-21
EP2353004A4 (en) 2012-04-18
US9267945B2 (en) 2016-02-23
EP2353004B1 (en) 2018-01-03
WO2010055510A2 (en) 2010-05-20

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