JP2012167418A - Cap system for cooling head and keeping the head cool - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a cap system for cooling the head and keeping the head cool that applies a cooling load to the scalp of a patient who is subjected to radiation treatment, the cap system enabling high-accuracy, simple and long-term cooling and cold insulation without using an electric drive source such as a heat sink or recirculation motor, while keeping sanitary condition, and attaining various functions, such as reduction in the burden of the patient due to a change in temperature or prevention of incomplete cooling due to difference in the shape of the head different by individual.SOLUTION: The system for cooling head prevents hear loss during chemotherapy that uses a high-performance refrigerant as a cold source. The hair loss as a side effect of the chemotherapy is prevented or mitigated by adding the indirect cold load to the scalp by combining an under cap (100) made of the high temperature conduction material to be mounted on the head of the patient and an over cap (110) which is equipped with the high heat insulation part to separate the external atmosphere at the outer surface and the cool storage part where constant cold is stored at the inner surface.

Description

The present invention relates to a head-cooled cold-retaining cap used for the purpose of preventing side-effect hair loss during chemotherapy (anticancer drug treatment) and a system thereof.

Conventionally, chemotherapy (anticancer drug treatment) has an excellent track record of treatment, but it has also been a problem that it exhibits strong toxicity to normal cells. It is considered as one of the cells that are susceptible to hair loss, and the resulting hair loss is one of the inevitable side effects. Prevention of this side effect hair loss by head cooling has been attempted. Specifically, the cooling load on the head suppresses blood flow to the hair matrix due to vasoconstriction and decreases metabolic activity. It is known that the damage to the hair matrix of the anticancer agent can be suppressed.

Based on such a viewpoint, a gel for cooling the head as disclosed in the following non-patent document is provided to prevent hair loss, which is one of the side effect reactions of chemotherapy (anticancer drug treatment). Yes. (Non-patent literature)
Some have large-scale equipment that circulates the aqueous liquid cooled by the cooling device to the head. (Patent Literature)

Bulletin of Kobe City College of Nursing No.15, 1996.3 Trial for hair loss prevention during administration of anticancer drugs

Special table 2010-517717

In the case of the above-described conventional cooling agent cap cooling (non-patent literature), since the time that the head can be cooled is short and unstable, harmful reactions are combined with the necessity of complicated cooling agent replacement work in the middle There is a possibility that a sufficient suppression effect and relaxation effect cannot be obtained. Also, with the conventional cryogen cap, since the cold heat of the cryogen directly touches the scalp when worn on the head, the temperature change is sudden and very cold and uncomfortable, and the burden on the patient is large There was also.

In the case of cooling device cooling (patent document), of course, the temperature adjustment and the extension of the cooling time are of course improved, such as a flexible head cooling pad corresponding to a different head shape for each patient has been made, Maintaining patient comfort by requiring uncomfortable and painful techniques such as wet-cooling the hair after wetting it with water in fine adjustment to partial incomplete cooling due to wearing differences caused by individual differences in head shape However, since it is a high-priced medical device, its general applicability is poor.

Therefore, the present invention has a long cooling time, a stable target cooling temperature, a suppression of partial incomplete cooling due to differences in individual differences, an unpleasant cooling sensation, and comfort. The purpose of the present invention is to provide the above-described improved method and system.

The present invention has been made in view of the above problems, and is a head-cooled cold-retention cap system for preventing hair loss during chemotherapy, which uses a high-performance regenerator as a cold heat source, An under cap (100) made of a high heat conduction material and a high heat insulating part (10) separating the external atmosphere on the outer surface part, and a cold load part (11) for storing a constant cold on the inner surface part and its cold heat In combination with a regenerative heat overcap (110) with a high heat conduction part (12) that evenly transmits to the entire part, it acts to prevent and alleviate side effects hair loss during chemotherapy by applying an indirect heat load to the scalp It is a configuration.

In the above-described head cooling / cold cap system of the present invention, the high-performance regenerator material (11a / 11b) enables temperature adjustment setting by adjusting the components, and is more accurate in the optimum temperature zone that prevents overcooling. It is preferable to perform temperature management and to achieve both a long-term temperature holding force.

In the head cooling / cold cap system of the present invention described above, it is preferable that the high thermal conductivity undercap (100) is formed by an individual-derived mold shape produced by molding into a head shape, and its outer surface. More preferably, overcap buffer portions (13a, 13b) having a thermal conductivity with a convex cross-sectional shape are formed on the entire circumference of the portion.

In the above-described head cooling / cold cap system of the present invention, it is preferable that the individual-derived shape high heat conduction undercap (100) is formed of a heat conductive material (aluminum wire or the like) having an infinite number of continuous network structures. In addition, it is more preferable to adjust the thermal conductivity by selecting the mesh width.

In the head cooling / cold cap system of the present invention described above, the cold storage heat overcap (110) is connected to the high heat insulation portion (10), the cold load portion (11), and the high heat conduction portion (12) from the outer surface portion. It is preferably formed by a combined three-layer structure, and two of them, the heat load portion (11), is a cover with a cold storage agent dispersed filling pocket made of a flexible resin, and the high heat conduction portion (12) is impregnated with carbon It is even more preferable that the high heat conduction undercap (100) made of resin is combined into a shape suitable for enveloping.

The operation of the first problem solving means is as follows.
In a head cooling method performed by being mounted on a patient's head, indirect space cooling by a combination of a cold heat receiving side undercap (100) and a cold heat discharge side overcap (110). By adopting a cooling and heating system, it is possible to maintain a stable target cooling temperature that is not misaligned, and to alleviate the unpleasant cooling sensation caused by a sudden drop in the scalp temperature during wearing, providing a refreshing feeling and comfort. Can exert the effect of working on the sustainability of

In addition, the function of the second problem solving means is that the high-performance regenerator (13) enables temperature adjustment setting by component adjustment and a long-term temperature holding power, so that the optimum temperature range in which overcooling is prevented. In addition to making it possible to maintain a more stable target cooling temperature, it is possible to exert an effect of making it unnecessary to replace a complicated cooling agent in the middle.

In addition, the action of the third problem solving means is that the cold cap-receiving undercap (100) is
By adding 13b), a constant gap space that avoids direct contact while adjusting the gap difference with the thermal load section (11), which is a common occurrence point of partial incomplete cooling, The effect of working to suppress incomplete cooling due to mounting differences from individual differences can be exhibited.
Incidentally, the mold making for each patient follows the usual method performed at the time of manufacturing the wig.

The fourth problem solving means is that the individual-derived shape high heat conduction undercap (100) is a heat conduction material made of aluminum wire or the like, and its mesh width is selected (extra fine (M1). By adjusting the thermal conductivity for medium eyes (M2), coarse eyes (M3), etc., it is possible to correct for incomplete cooling due to differences in the degree of heat transfer to the scalp in different hair volumes for each patient. The effect of doing can be demonstrated.

Furthermore, the action by the fifth problem solving means is that the high function regenerator overcap (110) is combined with the high heat insulation part (10), the cold load part (11), and the high heat conduction part (12) from the outer surface part. It is formed of a three-layer structure, and includes two points, a thermal load portion (11) comprising a mounting cover with a cold storage agent-dispersed filling pocket made of a flexible resin, and a high thermal conductive undercap (100) made of a carbon-impregnated resin. In the combined form with the high heat conduction part (12) of suitable shape, the installation of the cold storage agent to the cold heat load part (11) is stopped partially (minimum adoption), but the deviation of the cold It works to adjust to a uniform and uniform cooling load and reduce weight, and to transmit an efficient cooling load to the high thermal conductivity undercap (100), and at the same time prevent re-freezing after use. Highly insulated portion separation of (10) can exhibit an effect that is facilitated that.

According to the head cooling / cold cap system of the present invention, it is possible to work on prevention / mitigation of adverse reactions during chemotherapy by cooling the head with a simple structure, and the procedure is not complicated. Even if time is long, the following effects can be produced.

Since the head cooling cold insulation cap system of the present invention is cooled using a high-performance regenerator as a cold heat source, it is complicated in the middle of cooling during chemotherapy that normally requires about 1.5 hours. It eliminates the need for replacement work, and also exhibits a sufficient cooling effect in preventing and mitigating harmful reactions while maintaining a stable target cooling temperature similar to a cooling device using an electric drive source.

The above-described head cooling / cold cap system according to the present invention includes a cold heat receiving side undercap (100) mounted on a patient's head, and a cold heat discharge side overcap (110) mounted additionally from above. Indirect cooling load system for space cooling by combining with)) maintains a stable target cooling temperature without deviation and mitigates the unpleasant cooling sensation due to a sudden drop in scalp temperature when worn. At the same time, it is possible to provide a head-cooling / cold cap system that distinguishes between what is worn and what is repeatedly put in the refrigerator.

In the above-described head cooling / cold cap system according to the present invention, the high heat conduction undercap (100) is manufactured by an individual-derived mold shape by molding into a head shape, so that the cold storage heat overcap (110) A more effective cooling effect is exhibited by adjusting the gap difference from the cooling / heating load section (11) and working to suppress partial incomplete cooling due to mounting differences from individual differences.

Furthermore, the head cooling / cold cap system according to the present invention is based on the fact that interest in hair loss prevention during chemotherapy is increasing, and that it is relatively easy to make an individual-derived shape-matched product. High-performance regenerators are already used for transporting blood samples and in-flight meals that require precise temperature control over a long period of time, and because they use the action of food additives, there is no problem in terms of safety. Therefore, there are great expectations for its practical application.

It is the schematic which shows use of the head cooling cold-retention cap system of this invention which comprises the structure of 2 systems which puts a cool storage heat | fever overcap on the high heat conduction undercap | cover directly attached to a patient. It is an exploded view which shows the assembly of the cool storage heat | fever overcap of FIG. It is sectional drawing which shows the horizontal buffer part and the vertical buffer part of the high thermal conductivity undercap of FIG. It is the top view which looked at the example of the mesh width of the raw material which has the network structure of the high thermal conductivity undercap of FIG. It is a graph which shows the temperature followability and the cooling maintenance time by every temperature setting adjustment of a highly functional cool storage agent. It is a graph which shows the cooling capacity and cooling maintenance time in use of the head cooling cold insulation cap system of this invention.

The head cooling / cold cap system capable of producing the effects as described above is a highly heat-conductive material that is mounted on the patient's head using a high-functional cold storage agent as a cold source, as shown in the explanatory drawing of FIG. Under cap (100), a high heat insulating part that separates the external atmosphere on the outer surface part, a cold load part (11) that stores constant cold on the inner surface part, and a high heat conduction part (12) that uniformly conveys the cold to the entire head And a cold storage heat overcap (110) provided with two systems.

Hereinafter, the head cooling / cold cap system according to the embodiment of the present invention will be described in detail with reference to FIGS.

FIG. 1 is an overall configuration diagram of a head cooling / cold cap system showing an embodiment of the present invention, and FIGS. 2 to 5 are schematic diagrams showing a detailed configuration thereof.

In these FIG. 1, 100 is an undercap made of a high thermal conductivity material, 110 is a cold storage heat overcap with a high performance cold storage agent, and the figure shows an undercap (100) that is first mounted on the patient's head. In addition, it shows how to use in combination with the overcap (110) which is additionally mounted from above.

In FIG. 2, from the details of the cold storage heat overcap provided with one of the high-performance cold storage agents, 10 is a highly heat insulating material, 11 is a cold load portion, and 11a to 11b are the cold storage space (rectangular / elliptical). ), 12 shows an example of a high heat conduction part.

3 to 5, from the details of the other undercap of the high thermal conductivity material, 13a and 13b in FIG. 3 are examples of arrangement of buffer portions (horizontal and vertical) applied to the outer surface of the cap. 4, 13a and 13b are cross sections of the buffer portion (horizontal and vertical), and M1 to M3 in FIG. 5 are examples of the mesh width of the undercap manufacturing material.

The usage method of the head cooling cold insulation cap system which has such a function is demonstrated with reference to FIGS.

First of all, under the pre-molding, an under cap made of highly heat-conductive material of individual-derived shape made from information such as the patient's individual hair volume, head shape, hairline, etc. is mounted on the head in the shape of 100 in FIG. To fit the patient's head shape and hairline.
The production of such an undercap is performed by selecting the mesh width of the material from the ultrafine M1, the medium mesh M2, and the coarse mesh M3 in FIG.
In addition, in the mold making, it follows the method used at the time of normal wig production.

Next, after attaching the cold storage heat part (the combined part of the cold heat load part and the high heat conduction part) subjected to the pre-freezing process to the high heat insulation part and assembling it in the shape of 110 in FIG. Overlay the top of the high thermal conductivity undercap.
In addition, freezing of this cold storage heat | fever part (coalescence part of a cold-heating load part and a high heat conduction part) is made suitable for 24 hours by the refrigerating capacity equivalent to a normal household refrigerator.

Then, depending on the injection time of chemotherapy (anticancer drug treatment) for each patient, preferably from 15 minutes before administration of the anticancer agent, about 60 minutes of administration time, and about 90 minutes in total 15 minutes after administration. It is mounted on the patient's head and the cold heat is applied to the scalp, thereby preventing and mitigating adverse reactions of anticancer drugs.

In addition, about the said high heat conduction undercap and the said cool storage heat | fever overcap demonstrated to the said figure, without changing to these, the change to various shapes and sizes can be aimed at according to the objective.

The present invention is not limited to the above-described embodiments, and various modifications and additions can be made based on the spirit of the present invention, and these are not excluded from the scope of the present invention.

Basic experiment example

Below, it demonstrates in detail using FIGS. 6-7 about the basic experiment example regarding the highly functional cool storage agent used as the base of the head cooling cold insulation cap system of this invention.

FIG. 6 is a graph showing temperature followability and cooling maintenance time for each temperature adjustment of the high-functional regenerator used in the present invention.

FIG. 7 is a graph showing the cooling capacity and the cooling maintenance time in the use of the head-cooled cold insulation cap system of the present invention.

In these FIG. 6, the high-performance regenerator was adjusted to + 3 ° C., 0 ° C., −5 ° C., −10 ° C., −18 ° C., −20 ° C., −25 ° C., and −30 ° C. The temperature followability and cooling maintenance time are shown depending on the conditions.
Cold storage environment: A 3 cm thick polystyrene foam is placed in a cardboard box, a foamed polystyrene box is placed on it, and a bag in which a mirror mat is further wound is placed.
Cold storage agent used: 10 pieces of 1 kg type Styrofoam box used in total: 10 kg External dimensions: 40 cm x 32.5 cm x 26.5 cm x 3 cm

FIG. 7 shows the state of cooling maintenance within + 15 ° C. by temperature monitoring at five points of the frontal head, the center of the head (the top of the head), the back of the head, the left side of the head, and the right side of the head.
Cold storage environment: room temperature 27 ℃
Cold storage agent used: -18 type used

DESCRIPTION OF SYMBOLS 100 High heat conduction undercap 110 Cold storage heat | fever overcap 10 High heat insulation part 11 Cooling load part 11a Square shape cool storage agent filling pocket 11b Top part elliptical cool storage agent filling pocket 12 High heat conduction part 13a Horizontal buffer part 13b Vertical buffer part M1 extra fine mesh material M2 medium mesh material M3 coarse mesh material

Claims (11)

A head-cooled cold-retaining cap system for preventing hair loss during chemotherapy, which uses a high-performance cold storage agent as a cold heat source, and an undercap (100) made of a highly heat-conductive material to be worn on a patient's head; Cold storage heat having a high heat insulation part (10) that separates the external atmosphere on the outer surface part, and a cold heat load part (11) that stores constant cold heat on the inner surface part and a high heat conduction part (12) that uniformly conveys the cold to the entire head In combination with the overcap (110), it is characterized by applying an indirect cooling load to the scalp,
Head cooling / cold cap system. The high-performance regenerator (11a, 11b) enables temperature adjustment setting over a long period of time by adjusting the components, and enables more accurate temperature management in an optimum temperature range that prevents overcooling. To
The head cooling / cold cap system according to claim 1. The high thermal conductivity undercap (100) is manufactured by an individual-derived shape by shaping the patient's head shape, thereby adjusting the gap difference between the cold storage heat overcap (110) and the cold load portion (11). And, it works to suppress partial incomplete cooling due to mounting differences from individual differences,
The head cooling / cold cap system according to claim 1. The high thermal conductivity undercap (100) has a horizontal buffer (13a) around the entire periphery of the outer surface.
By providing a width of 5 mm), it is characterized in that a constant gap space is maintained by avoiding direct contact of the overcap (110) with the cold load portion (11).
The head cooling cold insulation cap system in any one of Claims 1-3. The temperature adjustment is achieved by the space cooling in the gap between the convex M-shaped buffer portion (13b) of the high heat conduction undercap (100) and the cooling load portion (11) of the regenerative heat overcap (110). It is characterized by the fact that the entire scalp is kept cool and kept at a constant temperature, and the patient's pain due to a sudden drop in temperature at the time of wearing is prevented, and refreshment and comfort are maintained. ,
The head cooling cold insulation cap system in any one of Claims 1, 3, and 4. The high thermal conductivity undercap (100) is formed of a material having an infinite number of continuous network structures, and the thermal conductivity is selected in selecting the fine mesh (M1), medium mesh (M2), and coarse mesh (M3). It is characterized by allowing adjustment.
The head cooling cold insulation cap system in any one of Claims 1-3. The cold-storage heat overcap (110) is formed from the outer surface portion by a combined three-layer structure of a high heat insulation portion (10), a cold load portion (11), and a high heat conduction portion (12), and two of them The combined use of the cooling / heating load section (11) and the high heat conduction section (12) makes it complicated to assemble the high heat insulation section (10) during use and to remove it after use (refreezing operation). Along with working to simplify the attachment and detachment operations, it is characterized by enabling efficient freezing excluding the high thermal insulation part (10),
The head cooling cold insulation cap system in any one of Claims 1-3. When the high heat insulation part (10) of the regenerative heat overcap (110) has a hemispherical shape suitable for wrapping the cold load part (11), it can be installed in close contact with the cold load part (11). In addition, it is characterized by preventing thermal buffering from the outside air and contributing to more effective cooling load,
The fingertip cooling / cooling system according to claim 1 or 7. Cooling load portion (11) of the regenerative heat overcap (110) is made of a flexible resin excellent in heat resistance and cold resistance, and in a shape suitable for enveloping the high heat conduction portion (12), a regenerative agent dispersion type filling It has 6 square corners (11a) for pocket edges and 1 elliptical shape (11b) for the top of the head, which enables close installation to the high heat conduction part (12) and contributes to weight reduction. Features
The fingertip cooling / cooling system according to claim 1 or 7. The heat storage portion (12) of the cold storage heat overcap (110) is made of carbon-impregnated resin, thereby facilitating difficult processing such as a hemispherical shape suitable for enveloping the high heat conductivity undercap (100). And contributes to weight reduction,
The fingertip cooling / cooling system according to claim 1 or 7. Moreover, the unification of the cold load part (11) and the high heat conduction part (12) of the cold storage heat overcap (110) disperses the offset of the cold heat from the distributed regenerator in the cold load part (11). It works to adjust to a uniform cold load and is more efficiently transmitted to the high thermal conductivity undercap (100).
The fingertip cooling / cooling system according to claim 1 or 9-10.