JP2012132369A - Drive device for liquid supply device and liquid supply device - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an extremely compact liquid supply device having few failure factors, and capable of performing a smooth push-out operation for developing uniform push-out force over the entire moving processes of a plunger, and of supplying and stopping liquid in accordance with the desired process, and to provide a drive device for the same.SOLUTION: The drive device may be attached to the liquid supply device comprising a syringe and a plunger so as to be used. A mechanism is used, which moves the plunger in the liquid supply device by energy accumulated in a spiral spring, and moves and stops the plunger in accordance with the desired process.

Description

The present invention relates to a driving device for a liquid supply device and a liquid supply device. More specifically, the present invention can be used by being attached to a liquid supply apparatus constituted by a syringe and a plunger, and the plunger in the liquid supply apparatus is moved by the energy accumulated in the mainspring spring, and is desired. A liquid supply device driving device capable of moving and stopping the plunger according to the process of the above, and a liquid supply device using the driving device, and it is not necessary to push out the plunger manually, and the entire plunger movement A uniform extrusion force can be developed over the entire process, so that a smooth extrusion operation can be performed. The liquid can be supplied and stopped according to the desired process, and it is extremely compact and has few failure factors. In addition, the present invention relates to a liquid supply apparatus having excellent characteristics.

  2. Description of the Related Art Liquid supply devices that push and supply liquid in a syringe to a desired container or the like outside the syringe with a plunger are widely used in various places. Here, the method of using the external energy regardless of human power for the movement of the plunger at the time of extrusion includes the method using the elastic energy of the spring, the method using the driving force of the motor, or pushing the plunger with compressed gas Or the method etc. which are attracted | sucked with pressure reduction gas are mention | raise | lifted. Among these methods, the method using a spring is relatively simple in apparatus and advantageous in terms of cost. As one of the methods using a spring, Patent Document 1 discloses a medicine delivery system using a coil spring or a gas spring.

JP 2005-534433 A

  By the way, the present inventors need to supply and stop the liquid in accordance with a desired process, for example, in a liquid supply apparatus used in an automatic chemical reaction apparatus, and have few failures and smooth stability under high reliability. A high requirement level was set that operation is possible and compactness is required. However, a liquid supply apparatus that sufficiently satisfies all such requirements has not been realized.

In such a situation, the problem to be solved by the present invention can be used by being attached to a container constituted by a syringe and a plunger, and the plunger in the container is moved by the energy accumulated in the mainspring spring. A plunger drive device capable of moving and stopping the plunger according to a desired process, and a liquid supply device using the drive device, and it is not necessary to push out the plunger manually, and A uniform extrusion force can be expressed over the moving process, so that a smooth extrusion operation can be performed, liquid supply and stop can be performed according to the desired process, and it is extremely compact and has few failure factors. It is in the point which provides the liquid supply apparatus which has the characteristic outstanding in implementation.

  That is, the first invention of the present invention can be used by being attached to a container composed of a syringe and a plunger, and the plunger in the container is moved by the energy accumulated in the mainspring spring and is desired. This relates to a plunger driving device capable of moving and stopping the plunger according to the process.

  The second invention of the present invention includes a syringe and a plunger, and the plunger is inserted into the syringe in close contact with the syringe and slidable in the length direction of the syringe. A liquid supply device that pushes the liquid in the syringe out of the syringe from the liquid discharge port provided at one end of the syringe by the movement of the plunger, and the liquid in the syringe is discharged from the liquid discharge port of the syringe to the outside of the syringe. The present invention relates to a liquid supply apparatus having a function of moving the plunger by the energy accumulated in the mainspring spring and performing the movement and stop of the plunger according to a desired process in the liquid discharging process of pushing out.

According to the present invention, it can be used by being attached to a container composed of a syringe and a plunger, and the plunger in the container is moved by the energy accumulated in the mainspring spring, and the plunger is moved according to a desired process. Plunger driving device capable of stopping, and liquid supply device using the driving device, and it is not necessary to push out the plunger manually, and a uniform pushing force can be expressed over the whole movement process of the plunger Therefore, it is possible to perform a smooth extrusion operation, supply and stop the liquid according to the desired process, and it is extremely compact and has few failure factors, especially in industrial applications. A feeding device can be provided.

It is a figure which shows the whole liquid supply apparatus of this invention (at the time of initial setting). It is a figure which shows the whole liquid supply apparatus (midway of liquid supply operation | movement) of this invention. It is a figure which shows the example of the convex-shaped latching | locking part provided in the movable plate-shaped member. It is a figure which shows the example of the concave latching | locking part provided in the movable plate-shaped member.

  Hereinafter, embodiments for carrying out the present invention will be described in detail. Here, it should be noted that the examples described below are merely examples of preferred embodiments, and do not limit the scope of rights of the present invention. The numbers in parentheses correspond to the symbols in the figure. In this specification, the X-axis direction in FIGS. 1 and 2 is referred to as the length direction of the syringe, and the Y-axis direction is referred to as the direction perpendicular to the syringe.

  The liquid supply apparatus of the present invention includes a syringe (2) and a plunger (3) that is inserted into the syringe in close contact with the syringe and can slide in the syringe in the length direction of the syringe. It is a liquid supply apparatus which extrudes the liquid (1) in a syringe out of a syringe from the liquid discharge port (4) provided in the end of the syringe. In addition, the syringe in this invention is a cylindrical body (outer cylinder) which can hold | maintain a liquid, and a plunger is also called a pushing element.

  Such syringe-plunger type containers are widely used as, for example, disposable syringes. Such a general-purpose product can also be used for the liquid supply apparatus of the present invention, and the size and material are not limited. For example, it is possible to use a plastic syringe and plunger that are provided with an elastic gasket at the tip of the plunger to maintain airtightness. In this case, the plunger main body and the gasket may be formed integrally, or may be configured separately and fitted by means such as screwing.

  In the liquid supply apparatus of the present invention, the plunger is moved by the energy accumulated in the mainspring spring (5) in the liquid discharge step of pushing the liquid in the syringe out of the syringe from the liquid discharge port of the syringe. Regardless of the present invention, when a spring spring is used, the spring spring has an elastic force that differs greatly between when it is stretched and when it is restored, and therefore it is not possible to develop a uniform pushing force over the entire movement process of the plunger. Here, if the force applied to the plunger is excessive, the liquid discharge force will be excessive, causing inconvenience such as liquid leakage from the connecting portion of the device, while if the force applied to the plunger is excessively small, It is also inconvenient, for example, the progress stops. Since the liquid supply device according to the present invention uses the mainspring spring, there is no inconvenience as described above with respect to the spring spring, and substantially the same force can be applied to the plunger over the entire movement process of the plunger. . Note that the preferred strength range of the mainspring spring, that is, the range of the spring constant depends on the size of the syringe, the viscosity of the liquid to be filled, etc. It is preferable to determine by measuring the load. In a preferred embodiment, the spring constant of the spring to be used is, for example, 5 to 15 N when a 1 ml capacity syringe is filled with physiological saline or the like, and 10 to 100 N when a 5 ml syringe is filled with physiological saline or the like. .

  The liquid supply apparatus of the present invention has a function capable of moving and stopping the plunger according to a desired process. That is, by controlling the movement and stop of the plunger, it is possible to supply a desired amount of liquid at a desired time point, and when necessary, it has a function of performing the movement and stop operations a plurality of times.

  A preferred embodiment for realizing such a function is as follows. (See FIGS. 1 and 2)

  Means (6) for fixing the syringe and plunger moving means are provided.

  In short, the means for fixing the syringe is a means for preventing the syringe from moving when the plunger is moved. For example, the syringe may be fixed to a fixed base or a fixed column.

The plunger moving means includes a moving plate-like member (7) and a latch mechanism (17),
The moving plate member
Provided substantially parallel to the syringe,
A vertically long plate-like member movable in the length direction of the syringe,
A plunger push plate-like member (8) capable of coming into contact with the plunger is provided at the end of the plunger opposite to the syringe,
The free end (16) of the mainspring spring is connected at an arbitrary position so that the plunger can be moved toward the liquid discharge port by the elastic energy of the mainspring spring,
A member provided with at least one locking portion (9) in the longitudinal direction;
The latch mechanism
Provided close to the moving plate member,
A latch (10) capable of locking the locking portion;
When the plunger is stopped, the movement of the movable plate member is stopped by the latch acting on the locking portion (FIG. 1),
When discharging the liquid in the syringe, the latch is temporarily released from the latch, and the plunger moves by moving the plunger using the energy stored in the mainspring spring. Means.

  The movable plate-like member is a vertically long plate-like member. Here, the plate-like member is a concept including a so-called rod-like member in addition to a literal plate-like member.

  The movable plate member is provided with a plunger push plate member that can come into contact with the plunger head at the end of the plunger opposite to the syringe. In short, the push plate-like member may be a contact member that comes into contact with the end of the plunger opposite to the syringe and pushes the plunger to move it.

  As described above, the free end of the mainspring spring is connected to the movable plate member at an arbitrary position so that the plunger can be moved in the direction of the liquid discharge port by the elastic energy of the mainspring spring. That is, the movable plate member can receive the energy stored in the mainspring spring, and the plunger moves with the energy.

  The moving plate-like member is provided with at least one locking portion in the length direction. This locking portion and the latch mechanism described below cooperate to realize movement and stop of the movable plate-like member, that is, movement and stop of the plunger. The engaging part according to the present invention can preferably use a concave or convex structure. Specifically, the formation of protrusions on a flat surface (FIG. 3), cutting into a flat surface (FIG. 4), and the like can be given.

  The number and position of the locking portions provided on the movable plate-like member may be determined according to the actual usage of the liquid supply device of the present invention, but is usually 1-5. The position of each locking portion is provided at a position corresponding to the amount of liquid discharged from the syringe, that is, a position corresponding to the movement distance of the plunger required to discharge the required amount of liquid. For example, when using a syringe with a capacity of 10 mL and sequentially discharging 5 mL, 2.5 mL, and 2.5 mL of liquid, plungers for discharging 5 mL, 2.5 mL, and 2.5 mL of liquid from the syringe, respectively. The locking portions are provided in order at positions corresponding to the movement distances. Moreover, it is good also as a form which can change the position of a latching | locking part arbitrarily using a well-known screwing mechanism. In this case, if a memory corresponding to the amount of liquid discharged from the syringe is provided on the movable plate member, it is convenient for setting the position of the locking portion. By providing such a mechanism, the position of the locking portion can be freely set, and the position where the movable plate member is stopped, that is, the position where the plunger is stopped can be set freely. As a result, the liquid supply amount can be set freely.

  Prior to the start of operation, the movable plate member is locked so as to be locked by the latch at the position where the plunger filled with the liquid is set and stopped (that is, the position of the plunger when the syringe setting is completed). If the part is provided, the plunger can be maintained in the stopped state in the set completion state, which is convenient.

  The latch mechanism is provided in the vicinity of the movable plate member, and has a latch that can be locked with the locking portion. When the plunger is stopped, the latch acts on the locking portion, in other words, the latch is engaged. This is a mechanism having a structure in which the movement of the movable plate-like member is stopped by becoming an obstacle to the movement of the stop portion. Referring to the drawings, in a stopped state, the latch is pushed up by a spring (not shown) provided in the latch housing (11), and makes an acute contact with a locking portion provided on the movable plate member. The moving plate member is stopped (FIG. 1).

  The shape of the locking portion is preferably a shape surrounded by a line that is substantially perpendicular to the length direction and a line having an inclination or a curve. For example, when a convex locking portion is used, as shown in FIG. 3, it is surrounded by a line (18) that is substantially perpendicular to the length direction and a line (19) that has an inclination or a curve. The line may be in front of the moving direction of the moving plate-shaped member in the liquid discharging step, and the line having the slope or curve may be a structure in the rear of the moving direction of the moving plate-shaped member in the liquid discharging step. it can.

  On the other hand, taking a case where a concave locking portion is provided as an example, it is surrounded by a line (14) substantially perpendicular to the length direction and a line (15) having an inclination or a curve. A structure that is behind the moving direction of the moving plate-like member at the time of the process, and a line having an inclination or a curve is ahead of the moving direction of the moving plate-like member at the time of the liquid discharging step (FIG. 4). .

  With this structure, when the plunger is stopped, the latch pushed up by the spring provided in the latch housing abuts on the locking portion at an acute angle, so that the movement of the movable plate member is stopped. On the other hand, when the moving plate-shaped member is set prior to the liquid discharge process, that is, when the plate-shaped member is moved in the direction opposite to the liquid discharge port, the latch is in contact with the locking portion by an oblique line, so the latch is a syringe. Therefore, it can be moved smoothly without stopping because it does not catch on the locking portion. That is, it can be said that the shape of the locking portion as described above is a shape in which the latch does not become an obstacle to the movement of the locking portion when the movable plate member moves in the direction opposite to the liquid discharge process.

  In a preferred embodiment, the shape of the tip of the latch is also a shape surrounded by a line substantially perpendicular to the length direction and a line having an inclination or a curve, and the substantially perpendicular line is a moving plate shape during the liquid discharge process. The line is located behind the moving direction of the member, and the line having the slope or curve is located forward of the moving plate-like member in the moving direction during the liquid discharging step. With such a structure, the above operation using the latch mechanism can be performed more smoothly.

  As described above, when the plunger is stopped, the movable plate-like member is stopped by the action of the latch on the engaging portion. As a result, the movement of the plunger is also stopped. When the next liquid supply operation is required, the latch is temporarily released from the latch, and the plunger is pushed into the syringe by the spring force of the mainspring spring. The liquid is discharged from the syringe until the part is locked (FIG. 2). A known method can be used as a method of realizing the movement operation of the latch when the latching to the latching portion is once released by the latch. For example, a mechanism by excitation and demagnetization of the electromagnet provided in the latch housing can be used. Can be used.

  The method using an electromagnet uses, for example, a latch made of a magnet attracting material or a latch to which a magnet attracting material is bonded, and when the latch is moved into the latch housing (that is, the latch is moved to the locking portion). At the time of releasing the lock, it is possible to use a known method such as energizing an electromagnet fixed behind the latch to attract the magnet attractive material portion.

  A command for moving the latch when releasing the latch to the latching portion may be performed by a method of manually turning on the switch, or may be automated by computer control. As a method of automation by computer control, a known method (for example, see Table 2008-029734) can be applied.

  As described above, according to the present invention, the latch can be locked and released from the locking portion, that is, the liquid can be supplied and stopped as desired. In addition, in the present invention, since the energy of the mainspring spring is used to move the plunger, the manufacturing cost and the operating cost can be remarkably reduced compared with the technology using the driving force and aerodynamic force of the motor, and there is less failure. This makes stable operation possible. In addition, since the plunger is moved and stopped in a relatively simple structure such as a locking portion / latch mechanism, it is not necessary to use a complicated mechanical mechanism such as a gear, so that the manufacturing cost can be reduced and the failure frequency can be reduced. It can be made compact and can be made compact.

  Although the liquid supply apparatus of the present invention can be sufficiently understood from the above description, the present invention will be described with an example of a method of using the liquid supply apparatus of the present invention as a precaution.

  First, the liquid discharge port of the syringe is immersed in the liquid in an appropriate container, and the plunger is moved in the opposite direction to the liquid discharge port of the syringe, thereby sucking and filling the liquid into the syringe. The syringe is placed on a movable plate-like member that has been stretched by a necessary distance in the rear of the liquid discharge direction in advance, and is fixed and set so that the plunger push-plate-like member comes into contact with the end of the plunger opposite to the syringe ( FIG. 1). At this time, the mainspring spring is stretched and the elastic energy of the spring is accumulated. Since the engaging portion is provided so that the movement of the movable plate-like member is stopped by the latch when the setting is completed, the plunger can be maintained in the stopped state when the setting is completed.

  When the desired liquid supply start time arrives, switching by manual operation or a signal command from a computer is received, the electromagnet installed in the latch housing is energized, and the latch is perpendicular to the syringe, in other words, away from the locking portion (Fig. 2). As a result, the latch is released from the latch and the moving plate-like member is moved by the energy of the mainspring spring. As a result, the plunger starts moving toward the liquid discharge port, and the liquid is discharged from the liquid discharge port.・ Supplied. Next, by stopping energization of the electromagnet, the latch stored in the latch housing is pushed up by the spring provided in the latch housing and returns to the original position. Then, when the moving plate-like member moves to the position where the next locking portion provided on the moving plate-like member meets the latch, the latch becomes an obstacle to the movement of the locking portion at that position. Stops and the supply of liquid stops. Further, when the next liquid supply start time comes, the latch is released from the latch portion in the same manner as described above, and the liquid supply is resumed. This operation is repeated according to the set number of locking portions. In addition, when discharging all the liquid in a syringe at once (namely, when supplying the whole quantity of the liquid stored in the syringe to the automatic chemical reaction apparatus etc. which are mentioned later), an intermediate latching part is not provided, or When the locking portion is provided, the latch may be operated so that the latch is always in the unlocked state (that is, the electromagnet in the latch housing is always energized).

  The liquid supply apparatus of the present invention has excellent characteristics as described above, and can be optimally used for an automatic chemical reaction apparatus by taking advantage of the characteristics. The automatic chemical reaction apparatus supplies a predetermined amount of liquid to the reaction system stepwise in accordance with a desired synthesis scheme. By using the liquid supply apparatus according to the present invention, such liquid supply is simply and reliably performed. Things will be possible. Further, since mechanical power such as a stepping motor is not required for movement of the plunger when supplying the liquid, it is inexpensive and can reduce the risk of failure and the like.

  Examples of the automatic chemical synthesizer include a radiopharmaceutical automatic synthesizer. Although the use of an automatic radiopharmaceutical synthesizer is limited to areas where radioactivity is permitted, the liquid supply apparatus of the present invention is particularly advantageous for installation and use in such situations because of its excellent compactness. Examples of radiopharmaceuticals include [18F] fluorodeoxyglucose, [18F] 1-amino-3-fluorocyclobutanecarboxylic acid, and the like (for example, see Table 2008-029734).

  The liquid to be handled by the liquid supply apparatus of the present invention includes a paste having a high viscosity in addition to a liquid having a relatively low viscosity.

  The present invention includes a syringe and a plunger that is inserted into the syringe in close contact with the syringe and is slidable in the length direction of the syringe. The liquid in the syringe is provided at one end of the syringe by the movement of the plunger. It is a liquid supply device that pushes out the syringe from the liquid discharge port, and it is not necessary to push out the plunger manually, and since a uniform pushing force can be expressed over the entire movement process of the plunger, a smooth pushing operation can be executed. In addition, it is possible to supply and stop the liquid according to a desired process, and it can be applied to a liquid supply apparatus having particularly excellent characteristics in industrial implementation that is extremely compact and has few failure factors.

DESCRIPTION OF SYMBOLS 1 Liquid 2 Syringe 3 Plunger 4 Liquid discharge port 5 Mainspring spring 6 Means to fix a syringe 7 Moving plate member 8 Plunger push plate member 9 Locking portion
10 Latch
11 Latch housing
14 Concave part shape ... Line perpendicular to the length direction
15 Shape of concave locking part ... Line with slope or curve
16 Free end of mainspring
17 Latch mechanism
18 Convex locking part shape ... Line perpendicular to the length direction
19 Shape of convex locking part: Line with slope or curve

Claims (24)

  It can be used by being attached to a container composed of a syringe and a plunger, and the plunger in the container is moved by the energy stored in the mainspring spring, and the plunger is moved and stopped according to a desired process. Plunger drive device that can The drive device according to claim 1, further comprising means for fixing the syringe and plunger moving means described below.
Plunger moving means: including a moving plate member and a latch mechanism,
The moving plate member
Provided substantially parallel to the syringe,
A vertically long plate-like member movable in the length direction of the syringe,
A plunger push plate-like member capable of contacting the end of the plunger opposite to the syringe is provided,
The free end of the mainspring spring is connected at an arbitrary position so that the plunger can be moved in the direction of the liquid discharge port by the elastic energy of the mainspring spring.
A member provided with at least one concave locking portion in the length direction,
The latch mechanism
Provided close to the moving plate member,
A latch capable of locking the locking portion;
When the plunger is stopped, the movement of the movable plate-like member is stopped by the latch acting on the locking portion,
When discharging the liquid in the syringe, the latch is temporarily released from the latch, and the plunger moves by moving the plunger using the energy stored in the mainspring spring. means   The shape of the concave locking portion in the longitudinal cross section of the moving plate-shaped member is surrounded by a line that is substantially perpendicular to the length direction and a line having an inclination or a curve, and the vertical line is in the liquid discharge process 3. The drive device according to claim 2, wherein the driving plate is located rearward in the moving direction of the moving plate-like member, and a line having an inclination or a curve is located in front of the moving plate-like member in the moving direction during the liquid discharging step. The drive device according to claim 1, further comprising means for fixing the syringe and plunger moving means described below.
Plunger moving means: including a moving plate member and a latch mechanism,
The moving plate member
Provided substantially parallel to the syringe,
A vertically long plate-like member movable in the length direction of the syringe,
A plunger push plate-like member capable of contacting the end of the plunger opposite to the syringe is provided,
The free end of the mainspring spring is connected at an arbitrary position so that the plunger can be moved in the direction of the liquid discharge port by the elastic energy of the mainspring spring.
A member provided with at least one convex locking portion in the length direction,
The latch mechanism
Provided close to the moving plate member,
A latch capable of locking the locking portion;
When the plunger is stopped, the movement of the movable plate-like member is stopped by the latch acting on the locking portion,
When discharging the liquid in the syringe, the latch is temporarily released from the latch, and the plunger moves by moving the plunger using the energy stored in the mainspring spring. means   The shape of the convex locking portion in the longitudinal section of the movable plate-shaped member is surrounded by a line that is substantially perpendicular to the length direction and a line that has an inclination or a curve. The drive device according to claim 4, wherein the driving device is located in front of the moving plate member in the moving direction, and a line having an inclination or a curve is located in the rear of the moving plate member in the moving direction in the liquid discharging step. The moving plate-like member has a plurality of locking portions;
The plunger movement according to any one of claims 2 to 5, wherein the interval between the locking portions corresponds to a movement distance of the plunger required for discharging a predetermined amount of liquid in the syringe. means.   The driving apparatus according to claim 2, wherein the movement operation of the latch when releasing the latch to the latch portion is performed by excitation and demagnetization of the electromagnet.   The driving device according to any one of claims 2 to 7, wherein the switching for performing the moving operation of the latch when the latch is released from the latch by the latch is controlled manually or by a computer.   The drive device according to one of claims 1 to 8, which is used in an automatic chemical reaction device.   The drive device according to claim 9, wherein the automatic chemical synthesizer is a radiopharmaceutical automatic synthesizer.   The driving device according to claim 10, wherein the radiopharmaceutical is a positron emission-type preparation.   The driving device according to claim 11, wherein the radiopharmaceutical is [18F] fluorodeoxyglucose or [18F] 1-amino-3-fluorocyclobutanecarboxylic acid.   A syringe and a plunger, and the plunger is inserted into the syringe in close contact with the syringe and is slidable in the length direction of the syringe through the syringe. A liquid supply device that pushes liquid out of the syringe from a liquid discharge port provided at one end of the syringe, and in the liquid discharge step of pushing the liquid in the syringe out of the syringe from the liquid discharge port, the movement of the plunger is mainspring. A liquid supply apparatus having a function of being moved by the energy accumulated in the spring and moving and stopping the plunger according to a desired process. The liquid supply apparatus according to claim 13, comprising means for fixing the syringe and plunger moving means described below.
Plunger moving means: including a moving plate member and a latch mechanism,
The moving plate member
Provided substantially parallel to the syringe,
A vertically long plate-like member movable in the length direction of the syringe,
A plunger push plate-like member capable of contacting the end of the plunger opposite to the syringe is provided,
The free end of the mainspring spring is connected at an arbitrary position so that the plunger can be moved in the direction of the liquid discharge port by the elastic energy of the mainspring spring.
A member provided with at least one concave locking portion in the length direction,
The latch mechanism
Provided close to the moving plate member,
A latch capable of locking the locking portion;
When the plunger is stopped, the movement of the movable plate-like member is stopped by the latch acting on the locking portion,
When discharging the liquid in the syringe, the latch is temporarily released from the latch, and the plunger moves by moving the plunger using the energy stored in the mainspring spring. means   The shape of the concave locking portion in the longitudinal cross section of the moving plate-shaped member is surrounded by a line that is substantially perpendicular to the length direction and a line having an inclination or a curve, and the vertical line is in the liquid discharge process The liquid supply apparatus according to claim 14, wherein the liquid supply apparatus is located behind the moving plate-like member in the moving direction, and a line having an inclination or a curve is located ahead of the moving plate-like member in the moving direction during the liquid discharging step. The liquid supply apparatus according to claim 13, comprising means for fixing the syringe and plunger moving means described below.
Plunger moving means: including a moving plate member and a latch mechanism,
The moving plate member
Provided substantially parallel to the syringe,
A vertically long plate-like member movable in the length direction of the syringe,
A plunger push plate-like member capable of contacting the end of the plunger opposite to the syringe is provided,
The free end of the mainspring spring is connected at an arbitrary position so that the plunger can be moved in the direction of the liquid discharge port by the elastic energy of the mainspring spring.
A member provided with at least one convex locking portion in the length direction,
The latch mechanism
Provided close to the moving plate member,
A latch capable of locking the locking portion;
When the plunger is stopped, the movement of the movable plate-like member is stopped by the latch acting on the locking portion,
When discharging the liquid in the syringe, the latch is temporarily released from the latch, and the plunger moves by moving the plunger using the energy stored in the mainspring spring. means   The shape of the convex locking portion in the longitudinal section of the movable plate-shaped member is surrounded by a line that is substantially perpendicular to the length direction and a line that has an inclination or a curve. The liquid supply apparatus according to claim 16, wherein the liquid supply device is in front of the moving plate-shaped member in the moving direction, and a line having an inclination or a curve is in the rear of the moving plate-shaped member in the moving direction in the liquid discharging step. The moving plate-like member has a plurality of locking portions;
The plunger movement according to any one of claims 14 to 17, wherein the interval between the locking portions corresponds to a movement distance of the plunger required for discharging a predetermined amount of liquid in the syringe. means.   The liquid supply apparatus according to any one of claims 14 to 18, wherein the movement operation of the latch when releasing the latch to the latch portion is performed by excitation and demagnetization of the electromagnet.   The liquid supply device according to any one of claims 14 to 19, wherein the switching for performing the movement operation of the latch when releasing the latch to the latch portion is controlled by a manual operation or a computer. .   21. The liquid supply apparatus according to claim 13, which is used in an automatic chemical reaction apparatus.   The liquid supply apparatus according to claim 21, wherein the automatic chemical synthesizer is a radiopharmaceutical automatic synthesizer.   The liquid supply apparatus according to claim 22, wherein the radiopharmaceutical is a positron emission-type preparation.   The liquid supply apparatus according to claim 22, wherein the radiopharmaceutical is [18F] fluorodeoxyglucose or [18F] 1-amino-3-fluorocyclobutanecarboxylic acid.