JP2012125257A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012125257A5 JP2012125257A5 JP2012077593A JP2012077593A JP2012125257A5 JP 2012125257 A5 JP2012125257 A5 JP 2012125257A5 JP 2012077593 A JP2012077593 A JP 2012077593A JP 2012077593 A JP2012077593 A JP 2012077593A JP 2012125257 A5 JP2012125257 A5 JP 2012125257A5
- Authority
- JP
- Japan
- Prior art keywords
- virus
- ribozyme
- microorganism
- composition
- indicator
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000000034 method Methods 0.000 claims 18
- 210000004027 cell Anatomy 0.000 claims 12
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 9
- 241000700605 Viruses Species 0.000 claims 8
- 108090000994 Catalytic RNA Proteins 0.000 claims 7
- 102000053642 Catalytic RNA Human genes 0.000 claims 7
- 244000005700 microbiome Species 0.000 claims 7
- 108091092562 ribozyme Proteins 0.000 claims 7
- 230000001717 pathogenic effect Effects 0.000 claims 6
- 231100000255 pathogenic effect Toxicity 0.000 claims 6
- 239000000126 substance Substances 0.000 claims 6
- 102000040650 (ribonucleotides)n+m Human genes 0.000 claims 5
- 238000003776 cleavage reaction Methods 0.000 claims 2
- 230000000120 cytopathologic effect Effects 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 210000005260 human cell Anatomy 0.000 claims 2
- 239000012678 infectious agent Substances 0.000 claims 2
- 208000015181 infectious disease Diseases 0.000 claims 2
- 210000005170 neoplastic cell Anatomy 0.000 claims 2
- 230000010076 replication Effects 0.000 claims 2
- 230000007017 scission Effects 0.000 claims 2
- 108020000999 Viral RNA Proteins 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US36073002P | 2002-02-28 | 2002-02-28 | |
| US60/360,730 | 2002-02-28 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008235697A Division JP2009005712A (ja) | 2002-02-28 | 2008-09-12 | 外来性の物質の検出におけるリボザイムの使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012125257A JP2012125257A (ja) | 2012-07-05 |
| JP2012125257A5 true JP2012125257A5 (enExample) | 2013-06-20 |
| JP5615865B2 JP5615865B2 (ja) | 2014-10-29 |
Family
ID=27766245
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003571491A Expired - Fee Related JP4369243B2 (ja) | 2002-02-28 | 2003-02-26 | 外来性の物質の検出におけるリボザイムの使用 |
| JP2008235697A Withdrawn JP2009005712A (ja) | 2002-02-28 | 2008-09-12 | 外来性の物質の検出におけるリボザイムの使用 |
| JP2012077593A Expired - Lifetime JP5615865B2 (ja) | 2002-02-28 | 2012-03-29 | 外来性の物質の検出におけるリボザイムの使用 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003571491A Expired - Fee Related JP4369243B2 (ja) | 2002-02-28 | 2003-02-26 | 外来性の物質の検出におけるリボザイムの使用 |
| JP2008235697A Withdrawn JP2009005712A (ja) | 2002-02-28 | 2008-09-12 | 外来性の物質の検出におけるリボザイムの使用 |
Country Status (16)
| Country | Link |
|---|---|
| EP (2) | EP1481084B1 (enExample) |
| JP (3) | JP4369243B2 (enExample) |
| AR (1) | AR038849A1 (enExample) |
| AT (1) | ATE519860T1 (enExample) |
| AU (1) | AU2003206587B2 (enExample) |
| BR (1) | BR0307882A (enExample) |
| CA (1) | CA2374388C (enExample) |
| DE (1) | DE03704136T1 (enExample) |
| DK (1) | DK1481084T3 (enExample) |
| ES (1) | ES2241506T3 (enExample) |
| MX (1) | MXPA04008277A (enExample) |
| NZ (1) | NZ534488A (enExample) |
| TR (1) | TR200501513T3 (enExample) |
| TW (1) | TWI329132B (enExample) |
| WO (1) | WO2003072811A2 (enExample) |
| ZA (1) | ZA200406231B (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1306959C (zh) * | 2004-09-21 | 2007-03-28 | 中国科学院武汉病毒研究所 | 草鱼呼肠孤病毒抗原亚单位疫苗制备方法 |
| US10668119B2 (en) | 2005-08-01 | 2020-06-02 | Virocure, Inc. | Attenuated reovirus |
| US10260049B2 (en) | 2005-08-01 | 2019-04-16 | Virocure, Inc. | Attenuated reovirus |
| US10369171B2 (en) | 2007-03-13 | 2019-08-06 | Virocure, Inc. | Attenuated reoviruses for selection of cell populations |
| TW201738562A (zh) * | 2009-05-28 | 2017-11-01 | 亞培生物股份有限公司 | 體外病原體檢驗技術 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4987071A (en) | 1986-12-03 | 1991-01-22 | University Patents, Inc. | RNA ribozyme polymerases, dephosphorylases, restriction endoribonucleases and methods |
| US5254678A (en) | 1987-12-15 | 1993-10-19 | Gene Shears Pty. Limited | Ribozymes |
| US5168053A (en) | 1989-03-24 | 1992-12-01 | Yale University | Cleavage of targeted RNA by RNAase P |
| US5225347A (en) | 1989-09-25 | 1993-07-06 | Innovir Laboratories, Inc. | Therapeutic ribozyme compositions and expression vectors |
| US5225337A (en) | 1989-09-25 | 1993-07-06 | Innovir Laboratories, Inc. | Ribozyme compositions and methods for use |
| ATE236975T1 (de) | 1992-07-02 | 2003-04-15 | Sankyo Co | Haarnadelförmiges ribozym |
| AU679525B2 (en) * | 1992-12-04 | 1997-07-03 | Innovir Laboratories, Inc. | Regulatable nucleic acid therapeutic and methods of use thereof |
| ES2134346T3 (es) | 1993-02-16 | 1999-10-01 | Onyx Pharma Inc | Virus citopatico para el tratamiento y la profilaxis de la neoplasia. |
| AU699487B2 (en) | 1993-04-30 | 1998-12-03 | Robert M. Lorence | Methods of treating and detecting cancer using viruses |
| WO1995010608A1 (en) * | 1993-10-15 | 1995-04-20 | Foundation For Research And Technology - Hellas (Fo.R.T.H.) | Asymmetric hammerhead ribozymes and nucleotide sequences for their construction |
| US5631359A (en) | 1994-10-11 | 1997-05-20 | Ribozyme Pharmaceuticals, Inc. | Hairpin ribozymes |
| US6107027A (en) * | 1994-12-14 | 2000-08-22 | University Of Washington | Ribozymes for treating hepatitis C |
| US6110461A (en) * | 1997-08-13 | 2000-08-29 | Oncolytics Biotech Inc. | Reovirus for the treatment of neoplasia |
| US6136307A (en) | 1997-08-13 | 2000-10-24 | Oncolytics Biotech Inc. | Reovirus for the treatment of cellular proliferative disorders |
| JP2001519175A (ja) | 1997-10-09 | 2001-10-23 | プロ − バイラス,インコーポレイテッド | ウイルスを用いた新生物の処置 |
| EP1066312A4 (en) | 1998-03-28 | 2002-01-02 | Univ Utah Res Found | HAMMER HEAD RIBOZYMES AND THEIR DERIVATIVES AS CIRCULAR, HAIRPIN, CIRCULAR / HAIRPIN, LASSO, HAIRPIN / LASSO |
| AU6522599A (en) * | 1998-10-23 | 2000-05-15 | Children's Medical Center Corporation | Use of a self-cleaving rna motif to modulate gene expression |
| AU2001251004A1 (en) * | 2000-03-27 | 2001-10-08 | Smith Kline Beecham Corporation | Detection of viable agents |
| TWI289158B (en) | 2000-08-10 | 2007-11-01 | Oncolytics Biotech Inc | Method of producing infectious reovirus |
-
2002
- 2002-03-04 CA CA002374388A patent/CA2374388C/en not_active Expired - Fee Related
-
2003
- 2003-02-25 TW TW092103911A patent/TWI329132B/zh not_active IP Right Cessation
- 2003-02-26 DE DE03704136T patent/DE03704136T1/de active Pending
- 2003-02-26 BR BR0307882-5A patent/BR0307882A/pt not_active IP Right Cessation
- 2003-02-26 AR ARP030100637A patent/AR038849A1/es unknown
- 2003-02-26 MX MXPA04008277A patent/MXPA04008277A/es active IP Right Grant
- 2003-02-26 AU AU2003206587A patent/AU2003206587B2/en not_active Ceased
- 2003-02-26 ES ES03704136T patent/ES2241506T3/es not_active Expired - Lifetime
- 2003-02-26 WO PCT/CA2003/000264 patent/WO2003072811A2/en not_active Ceased
- 2003-02-26 TR TR2005/01513T patent/TR200501513T3/xx unknown
- 2003-02-26 DK DK03704136.5T patent/DK1481084T3/da active
- 2003-02-26 NZ NZ534488A patent/NZ534488A/en unknown
- 2003-02-26 EP EP03704136A patent/EP1481084B1/en not_active Expired - Lifetime
- 2003-02-26 AT AT03704136T patent/ATE519860T1/de not_active IP Right Cessation
- 2003-02-26 JP JP2003571491A patent/JP4369243B2/ja not_active Expired - Fee Related
- 2003-02-26 EP EP11176991A patent/EP2439286A1/en not_active Withdrawn
-
2004
- 2004-08-04 ZA ZA2004/06231A patent/ZA200406231B/en unknown
-
2008
- 2008-09-12 JP JP2008235697A patent/JP2009005712A/ja not_active Withdrawn
-
2012
- 2012-03-29 JP JP2012077593A patent/JP5615865B2/ja not_active Expired - Lifetime
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Mishra et al. | The interplay between viral-derived miRNAs and host immunity during infection | |
| Sakai et al. | The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses | |
| Morales et al. | SARS-CoV-encoded small RNAs contribute to infection-associated lung pathology | |
| Zheng et al. | Human microRNA hsa-miR-296-5p suppresses enterovirus 71 replication by targeting the viral genome | |
| Huang et al. | Establishment of a reverse genetics system for studying human bocavirus in human airway epithelia | |
| Gao et al. | The influenza A virus PB2, PA, NP, and M segments play a pivotal role during genome packaging | |
| Noda et al. | Characterization of the Ebola virus nucleoprotein–RNA complex | |
| Devignot et al. | A virus-like particle system identifies the endonuclease domain of Crimean-Congo hemorrhagic fever virus | |
| Meyer et al. | Aerosolized Ebola vaccine protects primates and elicits lung-resident T cell responses | |
| Thornburg et al. | Respiratory syncytial virus regulates human microRNAs by using mechanisms involving beta interferon and NF-κB | |
| Sajid et al. | siRNA Therapeutics for the Therapy of COVID-19 and Other Coronaviruses | |
| Vázquez-Calvo et al. | Acid-dependent viral entry | |
| Bradfute et al. | Functional CD8+ T cell responses in lethal Ebola virus infection | |
| Krähling et al. | Establishment of fruit bat cells (Rousettus aegyptiacus) as a model system for the investigation of filoviral infection | |
| Zimmer et al. | Pseudotyping of vesicular stomatitis virus with the envelope glycoproteins of highly pathogenic avian influenza viruses | |
| TR201904215T4 (tr) | Bakteriyel yapay kromozomlar. | |
| JP2012125257A5 (enExample) | ||
| Simoneau et al. | Modeling multi-organ infection by SARS-CoV-2 using stem cell technology | |
| Min et al. | Mammalian adaptation in the PB2 gene of avian H5N1 influenza virus | |
| Xue et al. | Viral RNA N 6-methyladenosine modification modulates both innate and adaptive immune responses of human respiratory syncytial virus | |
| JP2016533172A5 (enExample) | ||
| Hoffmann et al. | The hemagglutinin of bat-associated influenza viruses is activated by TMPRSS2 for pH-dependent entry into bat but not human cells | |
| Bauer et al. | MicroRNAs: small but key players in viral infections and immune responses to viral pathogens | |
| Liao et al. | Host non-coding RNA regulates influenza A virus replication | |
| Avanthay et al. | NS1 and PA-X of H1N1/09 influenza virus act in a concerted manner to manipulate the innate immune response of porcine respiratory epithelial cells |