JP2011530306A - 甲状腺癌のリスクアセスメントに有用な遺伝的変異 - Google Patents

甲状腺癌のリスクアセスメントに有用な遺伝的変異 Download PDF

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JP2011530306A
JP2011530306A JP2011522616A JP2011522616A JP2011530306A JP 2011530306 A JP2011530306 A JP 2011530306A JP 2011522616 A JP2011522616 A JP 2011522616A JP 2011522616 A JP2011522616 A JP 2011522616A JP 2011530306 A JP2011530306 A JP 2011530306A
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marker
allele
thyroid cancer
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risk
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JP2011530306A5 (enExample
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ユリウス グッドムンドソン
ダニエル グッドブジャートソン
パトリック スレム
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ディコーデ ジェネテクス イーエイチエフ
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/046—Thyroid disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Hospice & Palliative Care (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2011522616A 2008-08-12 2009-08-12 甲状腺癌のリスクアセスメントに有用な遺伝的変異 Pending JP2011530306A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
IS8755 2008-08-12
IS8755 2008-08-12
IS8791 2009-02-05
IS8791 2009-02-05
PCT/IS2009/000010 WO2010018600A1 (en) 2008-08-12 2009-08-12 Genetic variants useful for risk assessment of thyroid cancer

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JP2011530306A true JP2011530306A (ja) 2011-12-22
JP2011530306A5 JP2011530306A5 (enExample) 2012-09-27

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US (1) US20110230366A1 (enExample)
EP (1) EP2334820A1 (enExample)
JP (1) JP2011530306A (enExample)
KR (1) KR20110081807A (enExample)
CN (1) CN102177252B (enExample)
AU (1) AU2009280807A1 (enExample)
CA (1) CA2733910A1 (enExample)
IL (1) IL211177A0 (enExample)
NZ (1) NZ591613A (enExample)
WO (1) WO2010018600A1 (enExample)

Cited By (2)

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KR20160051079A (ko) * 2014-10-31 2016-05-11 에스케이텔레콤 주식회사 갑상선암의 서브타입 분류용 조성물
JP2018515128A (ja) * 2015-03-18 2018-06-14 パティア バイオファーマ，エス．エー．ディーイー シー．ブイ． ２型糖尿病のための評価、予防、管理および処置選択のための方法、ツールおよびシステム

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US9495515B1 (en) 2009-12-09 2016-11-15 Veracyte, Inc. Algorithms for disease diagnostics
US10236078B2 (en) 2008-11-17 2019-03-19 Veracyte, Inc. Methods for processing or analyzing a sample of thyroid tissue
NZ593628A (en) * 2008-11-26 2013-07-26 Decode Genetics Ehf Genetic variants useful for risk assessment of thyroid cancer using rs944289
US8669057B2 (en) 2009-05-07 2014-03-11 Veracyte, Inc. Methods and compositions for diagnosis of thyroid conditions
EP2686443A4 (en) * 2011-03-17 2014-12-17 Decode Genetics Ehf GENETIC VARIANTS USEFUL IN ESTIMATING THE RISK OF THYROID CANCER
US8718950B2 (en) 2011-07-08 2014-05-06 The Medical College Of Wisconsin, Inc. Methods and apparatus for identification of disease associated mutations
WO2013088457A1 (en) * 2011-12-13 2013-06-20 Decode Genetics Ehf Genetic variants useful for risk assessment of thyroid cancer
US10260103B2 (en) 2012-11-27 2019-04-16 Pontificia Universidad Catolica De Chile Compositions and methods for diagnosing thyroid tumors
US11976329B2 (en) 2013-03-15 2024-05-07 Veracyte, Inc. Methods and systems for detecting usual interstitial pneumonia
JP7356788B2 (ja) 2014-11-05 2023-10-05 ベラサイト インコーポレイテッド 機械学習および高次元転写データを使用して経気管支生検における特発性肺線維症を診断するシステムおよび方法
CN106021992A (zh) * 2015-03-27 2016-10-12 知源生信公司（美国硅谷） 位置相关变体识别计算流水线
US10395759B2 (en) 2015-05-18 2019-08-27 Regeneron Pharmaceuticals, Inc. Methods and systems for copy number variant detection
KR102465122B1 (ko) 2016-02-12 2022-11-09 리제너론 파마슈티칼스 인코포레이티드 비정상적인 핵형을 검출하기 위한 방법 및 시스템
CN106636413B (zh) * 2016-12-28 2019-07-16 常州市第二人民医院 一种用于诊断哮喘的分子标志物
US11217329B1 (en) 2017-06-23 2022-01-04 Veracyte, Inc. Methods and systems for determining biological sample integrity
CN107194206A (zh) * 2017-06-26 2017-09-22 思畅信息科技（上海）有限公司 一种基于大数据的染色体异常位点的筛选方法
KR102081486B1 (ko) * 2017-08-01 2020-02-25 사회복지법인 삼성생명공익재단 Ahr 분류에 기반한 갑상선암 예후 예측 방법 및 시스템
KR102097540B1 (ko) * 2017-12-26 2020-04-07 주식회사 클리노믹스 질병 및 표현형 위험도 예측 장치 및 방법
CN108315425B (zh) * 2018-04-10 2021-08-06 广东省人民医院(广东省医学科学院) 甲状腺癌转移相关基因检测用的pcr特异性引物、试剂盒及其使用方法
US11216742B2 (en) 2019-03-04 2022-01-04 Iocurrents, Inc. Data compression and communication using machine learning
KR102169699B1 (ko) * 2019-12-27 2020-10-23 주식회사 클리노믹스 유전자 검사를 위한 맞춤형 유전자칩 및 이의 제작 방법
CN114694836B (zh) * 2020-12-30 2024-06-04 上海交通大学医学院附属瑞金医院 基于甲状腺癌淋巴结转移预测模型的评估系统

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JPN6014006310; ＰＲＡＺＥＲＥＳ，　Ｈ．Ｊ．　ｅｔ　ａｌ．: '"Ｌｏｓｓ　ｏｆ　ｈｅｔｅｒｏｚｙｇｏｓｉｔｙ　ａｔ　１９ｐ１３．２　ａｎｄ　２ｑ２１　ｉｎ　ｔｕｍｏｕｒｓ　ｆｒｏｍ　ｆａｍｉｌｉａｌ　ｃｌｕｓｔｅｒｓ　ｏｆ　ｎｏｎ-ｍｅｄｕｌｌａｒｙ　ｔｈｙｒｏ' ＦＡＭＩＬＩＡＬ　ＣＡＮＣＥＲ Ｖｏｌ．７，　Ｎｏ．２, 2008, Ｐ．１４１-１４９ *
JPN6014006311; ＢＡＳＯＬＯ，　Ｆ．　ｅｔ　ａｌ．: '"Ｔｈｙｒｏｉｄ　ｐａｐｉｌｌａｒｙ　ｃａｒｃｉｎｏｍａ：　ｐｒｅｌｉｍｉｎａｒｙ　ｅｖｉｄｅｎｃｅ　ｆｏｒ　ａ　ｇｅｒｍ-ｌｉｎｅ　ｓｉｎｇｌｅ　ｎｕｃｌｅｏｔｉｄｅ　ｐｏｌｙｍｏｒｐｈｉｓｍ　ｉｎ' ＪＯＵＲＮＡＬ　ＯＦ　ＥＮＤＯＣＲＩＮＯＬＯＧＹ Ｖｏｌ．１８２，　Ｎｏ．３, 200409, Ｐ．４７９-４８４ *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20160051079A (ko) * 2014-10-31 2016-05-11 에스케이텔레콤 주식회사 갑상선암의 서브타입 분류용 조성물
KR102011383B1 (ko) 2014-10-31 2019-08-16 에스케이텔레콤 주식회사 갑상선암의 서브타입 분류용 조성물
JP2018515128A (ja) * 2015-03-18 2018-06-14 パティア バイオファーマ，エス．エー．ディーイー シー．ブイ． ２型糖尿病のための評価、予防、管理および処置選択のための方法、ツールおよびシステム

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IL211177A0 (en) 2011-04-28
CN102177252A (zh) 2011-09-07
CN102177252B (zh) 2014-12-24
CA2733910A1 (en) 2010-02-18
EP2334820A1 (en) 2011-06-22
NZ591613A (en) 2013-01-25
US20110230366A1 (en) 2011-09-22
KR20110081807A (ko) 2011-07-14
WO2010018600A1 (en) 2010-02-18
AU2009280807A1 (en) 2010-02-18

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