JP2011522796A5 - - Google Patents

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Publication number
JP2011522796A5
JP2011522796A5 JP2011508615A JP2011508615A JP2011522796A5 JP 2011522796 A5 JP2011522796 A5 JP 2011522796A5 JP 2011508615 A JP2011508615 A JP 2011508615A JP 2011508615 A JP2011508615 A JP 2011508615A JP 2011522796 A5 JP2011522796 A5 JP 2011522796A5
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JP
Japan
Prior art keywords
peptide
seq
amino acids
nyad
composition
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011508615A
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English (en)
Japanese (ja)
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JP2011522796A (ja
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Priority claimed from PCT/US2009/042913 external-priority patent/WO2009137532A1/en
Publication of JP2011522796A publication Critical patent/JP2011522796A/ja
Publication of JP2011522796A5 publication Critical patent/JP2011522796A5/ja
Pending legal-status Critical Current

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JP2011508615A 2008-05-06 2009-05-05 抗ウイルス細胞透過性ペプチド Pending JP2011522796A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5095508P 2008-05-06 2008-05-06
US61/050,955 2008-05-06
PCT/US2009/042913 WO2009137532A1 (en) 2008-05-06 2009-05-05 Antiviral cell penetrating peptides

Publications (2)

Publication Number Publication Date
JP2011522796A JP2011522796A (ja) 2011-08-04
JP2011522796A5 true JP2011522796A5 (cg-RX-API-DMAC7.html) 2012-02-02

Family

ID=40957984

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011508615A Pending JP2011522796A (ja) 2008-05-06 2009-05-05 抗ウイルス細胞透過性ペプチド

Country Status (6)

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US (2) US8324153B2 (cg-RX-API-DMAC7.html)
EP (1) EP2283033A1 (cg-RX-API-DMAC7.html)
JP (1) JP2011522796A (cg-RX-API-DMAC7.html)
AU (1) AU2009244400B2 (cg-RX-API-DMAC7.html)
CA (1) CA2725227A1 (cg-RX-API-DMAC7.html)
WO (1) WO2009137532A1 (cg-RX-API-DMAC7.html)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8937154B2 (en) 2006-10-05 2015-01-20 New York Blood Center, Inc. Stabilized therapeutic small helical antiviral peptides
ES2387827T3 (es) * 2006-10-05 2012-10-02 New York Blood Center, Inc. Péptidos antivirales helicoidales, de pequeño tamaño, terapéuticos estabilizados
CA2677045C (en) 2007-01-31 2016-10-18 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
CA2682174C (en) 2007-03-28 2021-04-06 President And Fellows Of Harvard College Stitched polypeptides
EP2283033A1 (en) * 2008-05-06 2011-02-16 New York Blood Center Antiviral cell penetrating peptides
WO2012021875A1 (en) 2010-08-13 2012-02-16 Aileron Therapeutics, Inc. Peptidomimetic macrocycles with triazole linkers
WO2012137036A1 (en) * 2011-04-04 2012-10-11 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
EP2701725A1 (en) * 2011-04-29 2014-03-05 Kinemed, Inc. Chemical modification of apolipoprotein mimetic peptides for the production of therapeutic agents
CN108929375A (zh) 2011-10-18 2018-12-04 爱勒让治疗公司 拟肽大环化合物
CA2864120A1 (en) 2012-02-15 2013-08-22 Aileron Therapeutics, Inc. Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
CN112500466B (zh) 2012-02-15 2022-05-03 艾瑞朗医疗公司 拟肽大环化合物
WO2014053880A1 (en) 2012-10-04 2014-04-10 Centre National De La Recherche Scientifique Cell penetrating peptides for intracellular delivery of molecules
CN104812384B (zh) 2012-11-01 2020-09-18 爱勒让治疗公司 二取代的氨基酸及其制备和使用方法
EP3197478A4 (en) 2014-09-24 2018-05-30 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
US10905739B2 (en) 2014-09-24 2021-02-02 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and formulations thereof
CN105622732B (zh) * 2014-10-30 2019-10-25 中国科学院武汉病毒研究所 猴病毒40衣壳蛋白vp1在作为细胞穿膜蛋白中的应用
HUE046054T2 (hu) 2014-12-24 2020-01-28 Aadigen Llc Peptidek és nanorészecskék molekulák intracelluláris célba juttatásához
SG11201707750YA (en) 2015-03-20 2017-10-30 Aileron Therapeutics Inc Peptidomimetic macrocycles and uses thereof
CN108368161A (zh) 2015-09-10 2018-08-03 艾瑞朗医疗公司 作为mcl-1调节剂的拟肽大环化合物
AU2018385697B2 (en) 2017-12-15 2023-11-09 Dana-Farber Cancer Institute, Inc. Stabilized peptide-mediated targeted protein degradation
EP3749678A1 (en) 2018-02-07 2020-12-16 Dana Farber Cancer Institute, Inc. Cell-permeable stapled peptide modules for cellular delivery
AU2020288188A1 (en) * 2019-06-07 2022-01-27 Anders, Sonnerborg, Peptide inhibitors for the inhibition of hiv capsid
JP2023517293A (ja) * 2020-03-04 2023-04-25 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド 抗ウイルスの構造的に安定化されたSARS-CoV-2ペプチドおよびその使用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187548B1 (en) 1993-05-23 2001-02-13 Rhone-Poulenc Rorer Pharmaceuticals Inc. Methods using human calcium sensor protein, fragments thereof and DNA encoding same
US6239270B1 (en) 1993-05-24 2001-05-29 Rhone-Poulenc Rorer S.A. Nucleic acids encoding human calcium sensor protein
AU6727798A (en) * 1997-03-10 1998-09-29 Roche Diagnostics Gmbh Method for simultaneous detection of hiv antigens and hiv antibodies
NZ514883A (en) 1999-04-09 2004-03-26 Upjohn Co Anti-bacterial vaccine compositions
US6790950B2 (en) 1999-04-09 2004-09-14 Pharmacia & Upjohn Company Anti-bacterial vaccine compositions
US7192713B1 (en) 1999-05-18 2007-03-20 President And Fellows Of Harvard College Stabilized compounds having secondary structure motifs
AUPQ776100A0 (en) * 2000-05-26 2000-06-15 Australian National University, The Synthetic molecules and uses therefor
US20020124273A1 (en) 2000-10-17 2002-09-05 Jean-Marc Roch Protein-protein interactions in neurodegenerative diseases
WO2005044839A2 (en) 2003-11-05 2005-05-19 Dana-Farber Cancer Institute, Inc. Stabilized alpha helical peptides and uses thereof
WO2008008998A2 (en) 2006-07-13 2008-01-17 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in signaling pathways
WO2008009000A2 (en) 2006-07-13 2008-01-17 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in signaling pathways
MX2009002612A (es) 2006-09-11 2009-12-15 Univ Illinois Modoficaciones de péptidos derivados de cupredoxinas y métodos de uso de los mismos.
US8937154B2 (en) 2006-10-05 2015-01-20 New York Blood Center, Inc. Stabilized therapeutic small helical antiviral peptides
ES2387827T3 (es) * 2006-10-05 2012-10-02 New York Blood Center, Inc. Péptidos antivirales helicoidales, de pequeño tamaño, terapéuticos estabilizados
CA2677045C (en) 2007-01-31 2016-10-18 Dana-Farber Cancer Institute, Inc. Stabilized p53 peptides and uses thereof
JP5078401B2 (ja) * 2007-03-27 2012-11-21 株式会社Adeka 防水シート
EP2208061B1 (en) 2007-09-26 2017-11-08 Dana Farber Cancer Institute Methods and compositions for modulating bcl-2 family polypeptides
CA2713089C (en) 2008-01-23 2017-11-21 Dana Farber Cancer Institute Compositions and methods for the treatment of viral infections
EP2283033A1 (en) * 2008-05-06 2011-02-16 New York Blood Center Antiviral cell penetrating peptides
US20110218155A1 (en) 2008-10-10 2011-09-08 Dana-Farber Cancer Institute, Inc. Chemical modulators of pro-apoptotic bax and bcl-2 polypeptides

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