JP2011520781A5 - - Google Patents
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- Publication number
- JP2011520781A5 JP2011520781A5 JP2011503360A JP2011503360A JP2011520781A5 JP 2011520781 A5 JP2011520781 A5 JP 2011520781A5 JP 2011503360 A JP2011503360 A JP 2011503360A JP 2011503360 A JP2011503360 A JP 2011503360A JP 2011520781 A5 JP2011520781 A5 JP 2011520781A5
- Authority
- JP
- Japan
- Prior art keywords
- cell
- egf
- ms4a12
- activity
- agent according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004027 cell Anatomy 0.000 claims 27
- 239000003795 chemical substances by application Substances 0.000 claims 17
- 101000578853 Homo sapiens Membrane-spanning 4-domains subfamily A member 12 Proteins 0.000 claims 14
- 102100028425 Membrane-spanning 4-domains subfamily A member 12 Human genes 0.000 claims 14
- 230000000694 effects Effects 0.000 claims 11
- 206010028980 Neoplasm Diseases 0.000 claims 10
- 238000000034 method Methods 0.000 claims 10
- 230000004043 responsiveness Effects 0.000 claims 8
- 239000000203 mixture Substances 0.000 claims 6
- 201000011510 cancer Diseases 0.000 claims 5
- 230000004941 influx Effects 0.000 claims 5
- 206010027476 Metastases Diseases 0.000 claims 4
- 230000009401 metastasis Effects 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 102000001301 EGF receptor Human genes 0.000 claims 3
- 108060006698 EGF receptor Proteins 0.000 claims 3
- 206010009944 Colon cancer Diseases 0.000 claims 2
- 108020004459 Small interfering RNA Proteins 0.000 claims 2
- 230000000692 anti-sense effect Effects 0.000 claims 2
- 230000006369 cell cycle progression Effects 0.000 claims 2
- 230000001413 cellular effect Effects 0.000 claims 2
- 208000029742 colonic neoplasm Diseases 0.000 claims 2
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 108020004999 messenger RNA Proteins 0.000 claims 2
- 238000013508 migration Methods 0.000 claims 2
- 230000035755 proliferation Effects 0.000 claims 2
- 238000009736 wetting Methods 0.000 claims 2
- 230000034196 cell chemotaxis Effects 0.000 claims 1
- 230000010261 cell growth Effects 0.000 claims 1
- 230000012292 cell migration Effects 0.000 claims 1
- 230000035605 chemotaxis Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 230000012010 growth Effects 0.000 claims 1
- 230000003834 intracellular effect Effects 0.000 claims 1
- 230000005012 migration Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 210000004881 tumor cell Anatomy 0.000 claims 1
- 230000004614 tumor growth Effects 0.000 claims 1
- 230000035899 viability Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP08007109.5 | 2008-04-10 | ||
| EP08007109A EP2108701A1 (en) | 2008-04-10 | 2008-04-10 | Methods involving MS4A12 and agents targeting MS4A12 for therapy, diagnosis and testing |
| PCT/EP2009/002309 WO2009124670A1 (en) | 2008-04-10 | 2009-03-30 | Methods involving ms4a12 and agents targeting ms4a12 for therapy, diagnosis and testing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011520781A JP2011520781A (ja) | 2011-07-21 |
| JP2011520781A5 true JP2011520781A5 (cg-RX-API-DMAC7.html) | 2012-05-24 |
Family
ID=39811474
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011503360A Pending JP2011520781A (ja) | 2008-04-10 | 2009-03-30 | 治療、診断及び検査のためのｍｓ４ａ１２を伴う方法、及びｍｓ４ａ１２を標的とする剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20110027297A1 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2108701A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2011520781A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101998992A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2009235746A1 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2714997A1 (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ588177A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2009124670A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3263714B1 (en) * | 2015-02-24 | 2021-08-25 | Theoria Science Inc. | Method for diagnosing brain metastasis |
| CN109562379A (zh) | 2016-06-20 | 2019-04-02 | 拜克门寇尔特公司 | 用于染料共轭试剂的干燥过程 |
| US11472874B2 (en) | 2018-01-31 | 2022-10-18 | Alector Llc | Anti-MS4A4A antibodies and methods of use thereof |
| EP3746484A4 (en) | 2018-01-31 | 2021-11-17 | Alector LLC | ANTI-MS4A6A ANTIBODIES AND PROCESSES FOR USE |
| WO2021022083A2 (en) * | 2019-07-31 | 2021-02-04 | Alector Llc | Anti-ms4a4a antibodies and methods of use thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9019812D0 (en) | 1990-09-11 | 1990-10-24 | Scotgen Ltd | Novel antibodies for treatment and prevention of infection in animals and man |
| DE60140676D1 (de) | 2000-03-30 | 2010-01-14 | Massachusetts Inst Technology | Mediatoren von rns-interferenz, die rns-sequenzspezifisch sind |
| DE10211088A1 (de) * | 2002-03-13 | 2003-09-25 | Ugur Sahin | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
| DE10341812A1 (de) * | 2003-09-10 | 2005-04-07 | Ganymed Pharmaceuticals Ag | Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung |
-
2008
- 2008-04-10 EP EP08007109A patent/EP2108701A1/en not_active Withdrawn
-
2009
- 2009-03-30 EP EP09731038A patent/EP2265718A1/en not_active Withdrawn
- 2009-03-30 AU AU2009235746A patent/AU2009235746A1/en not_active Abandoned
- 2009-03-30 NZ NZ588177A patent/NZ588177A/en not_active IP Right Cessation
- 2009-03-30 WO PCT/EP2009/002309 patent/WO2009124670A1/en not_active Ceased
- 2009-03-30 CN CN2009801128194A patent/CN101998992A/zh active Pending
- 2009-03-30 CA CA2714997A patent/CA2714997A1/en not_active Abandoned
- 2009-03-30 US US12/937,178 patent/US20110027297A1/en not_active Abandoned
- 2009-03-30 JP JP2011503360A patent/JP2011520781A/ja active Pending
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