JP2011512367A5 - - Google Patents

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Publication number
JP2011512367A5
JP2011512367A5 JP2010547078A JP2010547078A JP2011512367A5 JP 2011512367 A5 JP2011512367 A5 JP 2011512367A5 JP 2010547078 A JP2010547078 A JP 2010547078A JP 2010547078 A JP2010547078 A JP 2010547078A JP 2011512367 A5 JP2011512367 A5 JP 2011512367A5
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JP
Japan
Prior art keywords
alkyl
alkylene
oxo
independently
unsubstituted
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JP2010547078A
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English (en)
Japanese (ja)
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JP2011512367A (ja
JP5422569B2 (ja
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Priority claimed from PCT/EP2009/000902 external-priority patent/WO2009103439A1/en
Publication of JP2011512367A publication Critical patent/JP2011512367A/ja
Publication of JP2011512367A5 publication Critical patent/JP2011512367A5/ja
Application granted granted Critical
Publication of JP5422569B2 publication Critical patent/JP5422569B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2010547078A 2008-02-21 2009-02-10 凝固第Ｘａ因子及びトロンビンの阻害剤としてのクロロチオフェン−イソオキサゾール類 Expired - Fee Related JP5422569B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08290166.1 2008-02-21
EP08290166 2008-02-21
PCT/EP2009/000902 WO2009103439A1 (en) 2008-02-21 2009-02-10 Chlorothiophene-isoxazoles as inhibitors of coagulation factors xa and thrombin

Publications (3)

Publication Number Publication Date
JP2011512367A JP2011512367A (ja) 2011-04-21
JP2011512367A5 true JP2011512367A5 (https=) 2012-03-22
JP5422569B2 JP5422569B2 (ja) 2014-02-19

Family

ID=39345612

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010547078A Expired - Fee Related JP5422569B2 (ja) 2008-02-21 2009-02-10 凝固第Ｘａ因子及びトロンビンの阻害剤としてのクロロチオフェン−イソオキサゾール類

Country Status (4)

Country Link
US (1) US8835653B2 (https=)
EP (1) EP2280964B1 (https=)
JP (1) JP5422569B2 (https=)
WO (1) WO2009103439A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103732589B (zh) 2011-05-25 2016-03-30 百时美施贵宝公司 可用作抗细胞凋亡bcl抑制剂的取代的磺酰胺
DE102012009811A1 (de) 2011-05-27 2012-11-29 Merck Patent Gmbh 1-Brom-3-Halo-2-Cycloalkylbenzol-Verbindungen
EP2907806A1 (en) * 2014-02-14 2015-08-19 Universita Degli Studi Di Genova New compounds as selective PDE4D inhibitors

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9322976D0 (en) * 1993-11-08 1994-01-05 Pfizer Ltd Therapeutic agents
US6313242B1 (en) * 1996-05-20 2001-11-06 Fina Technology, Inc. Stereorigid bis-fluorenyl metallocenes
WO2000075129A1 (en) * 1999-06-07 2000-12-14 Shire Biochem Inc. Thiophene integrin inhibitors
WO2001038309A1 (en) * 1999-11-24 2001-05-31 Cor Therapeutics, Inc. β-AMINO ACID-, ASPARTIC ACID- AND DIAMINOPROPIONIC-BASED INHIBITORS OF FACTOR Xa
GB0228552D0 (en) * 2002-12-06 2003-01-15 Glaxo Group Ltd Chemical compounds
CA2583267A1 (en) * 2004-10-12 2006-04-27 Amgen Inc. Novel b1 bradykinin receptor antagonists
DE102005048824A1 (de) * 2005-10-10 2007-04-12 Bayer Healthcare Ag Behandlung und Prophylaxe von Mikroangiopathien

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