JP2011507875A5 - - Google Patents
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- Publication number
- JP2011507875A5 JP2011507875A5 JP2010539742A JP2010539742A JP2011507875A5 JP 2011507875 A5 JP2011507875 A5 JP 2011507875A5 JP 2010539742 A JP2010539742 A JP 2010539742A JP 2010539742 A JP2010539742 A JP 2010539742A JP 2011507875 A5 JP2011507875 A5 JP 2011507875A5
- Authority
- JP
- Japan
- Prior art keywords
- tissue
- therapeutic implant
- therapeutic
- implant
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007943 implant Substances 0.000 claims 27
- 230000001225 therapeutic effect Effects 0.000 claims 27
- 229920000642 polymer Polymers 0.000 claims 13
- 239000011324 bead Substances 0.000 claims 12
- 238000000034 method Methods 0.000 claims 11
- 210000005084 renal tissue Anatomy 0.000 claims 11
- 210000001519 tissue Anatomy 0.000 claims 10
- 239000012634 fragment Substances 0.000 claims 7
- 235000010443 alginic acid Nutrition 0.000 claims 5
- 239000000783 alginic acid Substances 0.000 claims 5
- 229920000615 alginic acid Polymers 0.000 claims 5
- 229960001126 alginic acid Drugs 0.000 claims 5
- 150000004781 alginic acids Chemical class 0.000 claims 5
- 229920000729 poly(L-lysine) polymer Polymers 0.000 claims 5
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 3
- 244000215068 Acacia senegal Species 0.000 claims 3
- 229920000936 Agarose Polymers 0.000 claims 3
- 229920002134 Carboxymethyl cellulose Polymers 0.000 claims 3
- 102000012422 Collagen Type I Human genes 0.000 claims 3
- 108010022452 Collagen Type I Proteins 0.000 claims 3
- 229920002307 Dextran Polymers 0.000 claims 3
- 102000009123 Fibrin Human genes 0.000 claims 3
- 108010073385 Fibrin Proteins 0.000 claims 3
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 3
- 102000016359 Fibronectins Human genes 0.000 claims 3
- 108010067306 Fibronectins Proteins 0.000 claims 3
- 229920002907 Guar gum Polymers 0.000 claims 3
- 229920000084 Gum arabic Polymers 0.000 claims 3
- 102000007547 Laminin Human genes 0.000 claims 3
- 108010085895 Laminin Proteins 0.000 claims 3
- 239000002202 Polyethylene glycol Substances 0.000 claims 3
- 229920001615 Tragacanth Polymers 0.000 claims 3
- 235000010489 acacia gum Nutrition 0.000 claims 3
- 239000000205 acacia gum Substances 0.000 claims 3
- 239000000305 astragalus gummifer gum Substances 0.000 claims 3
- 239000001768 carboxy methyl cellulose Substances 0.000 claims 3
- 235000010948 carboxy methyl cellulose Nutrition 0.000 claims 3
- 239000008112 carboxymethyl-cellulose Substances 0.000 claims 3
- 229940105329 carboxymethylcellulose Drugs 0.000 claims 3
- 235000010418 carrageenan Nutrition 0.000 claims 3
- 239000000679 carrageenan Substances 0.000 claims 3
- 229920001525 carrageenan Polymers 0.000 claims 3
- 229940113118 carrageenan Drugs 0.000 claims 3
- 229950003499 fibrin Drugs 0.000 claims 3
- 235000010417 guar gum Nutrition 0.000 claims 3
- 239000000665 guar gum Substances 0.000 claims 3
- 229960002154 guar gum Drugs 0.000 claims 3
- 229920002674 hyaluronan Polymers 0.000 claims 3
- 229960003160 hyaluronic acid Drugs 0.000 claims 3
- 239000001814 pectin Substances 0.000 claims 3
- 229920001277 pectin Polymers 0.000 claims 3
- 235000010987 pectin Nutrition 0.000 claims 3
- 229960000292 pectin Drugs 0.000 claims 3
- 229920001223 polyethylene glycol Polymers 0.000 claims 3
- 235000010493 xanthan gum Nutrition 0.000 claims 3
- 239000000230 xanthan gum Substances 0.000 claims 3
- 229920001285 xanthan gum Polymers 0.000 claims 3
- 229940082509 xanthan gum Drugs 0.000 claims 3
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims 3
- 102100026802 72 kDa type IV collagenase Human genes 0.000 claims 2
- 101710151806 72 kDa type IV collagenase Proteins 0.000 claims 2
- 102000011690 Adiponectin Human genes 0.000 claims 2
- 108010076365 Adiponectin Proteins 0.000 claims 2
- 102100021943 C-C motif chemokine 2 Human genes 0.000 claims 2
- 101710155857 C-C motif chemokine 2 Proteins 0.000 claims 2
- 102000003951 Erythropoietin Human genes 0.000 claims 2
- 108090000394 Erythropoietin Proteins 0.000 claims 2
- 102000016267 Leptin Human genes 0.000 claims 2
- 108010092277 Leptin Proteins 0.000 claims 2
- 230000000735 allogeneic effect Effects 0.000 claims 2
- 229940105423 erythropoietin Drugs 0.000 claims 2
- 239000003102 growth factor Substances 0.000 claims 2
- 229940088597 hormone Drugs 0.000 claims 2
- 239000005556 hormone Substances 0.000 claims 2
- 229940039781 leptin Drugs 0.000 claims 2
- NRYBAZVQPHGZNS-ZSOCWYAHSA-N leptin Chemical compound O=C([C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)CNC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CC(C)C)CCSC)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CS)C(O)=O NRYBAZVQPHGZNS-ZSOCWYAHSA-N 0.000 claims 2
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 239000000725 suspension Substances 0.000 claims 2
- 208000024172 Cardiovascular disease Diseases 0.000 claims 1
- 208000006011 Stroke Diseases 0.000 claims 1
- 208000007502 anemia Diseases 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 238000004132 cross linking Methods 0.000 claims 1
- 239000001963 growth medium Substances 0.000 claims 1
- 208000017169 kidney disease Diseases 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1532807P | 2007-12-20 | 2007-12-20 | |
| US61/015,328 | 2007-12-20 | ||
| PCT/US2008/087211 WO2009085850A2 (en) | 2007-12-20 | 2008-12-17 | Encapsulated kidney tissue |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2011507875A JP2011507875A (ja) | 2011-03-10 |
| JP2011507875A5 true JP2011507875A5 (enExample) | 2012-02-16 |
| JP5456692B2 JP5456692B2 (ja) | 2014-04-02 |
Family
ID=40524488
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010539742A Expired - Fee Related JP5456692B2 (ja) | 2007-12-20 | 2008-12-17 | カプセル化された腎臓組織 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US8734527B2 (enExample) |
| EP (1) | EP2231209B1 (enExample) |
| JP (1) | JP5456692B2 (enExample) |
| CN (1) | CN101903049B (enExample) |
| AU (1) | AU2008343193B2 (enExample) |
| BR (1) | BRPI0821540B1 (enExample) |
| CA (1) | CA2708959C (enExample) |
| PL (1) | PL2231209T3 (enExample) |
| WO (1) | WO2009085850A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9125906B2 (en) | 2005-12-28 | 2015-09-08 | DePuy Synthes Products, Inc. | Treatment of peripheral vascular disease using umbilical cord tissue-derived cells |
| US8236538B2 (en) | 2007-12-20 | 2012-08-07 | Advanced Technologies And Regenerative Medicine, Llc | Methods for sterilizing materials containing biologically active agents |
| CN101903049B (zh) | 2007-12-20 | 2014-08-13 | 伊西康公司 | 包囊的肾组织 |
| WO2012154186A1 (en) * | 2011-05-12 | 2012-11-15 | Empire Technology Development Llc | Bioreactor for engineered tissue |
| US9555007B2 (en) | 2013-03-14 | 2017-01-31 | Massachusetts Institute Of Technology | Multi-layer hydrogel capsules for encapsulation of cells and cell aggregates |
| DE202013012287U1 (de) | 2013-04-23 | 2016-01-18 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Gelbildendes System zum Entfernen von Nierensteinfragmenten |
| EP2796101B1 (de) | 2013-04-23 | 2016-04-20 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Kit zum Herstellen eines vernetzten Gels zum Umschließen von Nierensteinen und/oder Nierensteinfragmenten |
| EP2796100B1 (de) | 2013-04-23 | 2016-04-20 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Gelbildendes System zum Entfernen von Nierensteinfragmenten |
| DE202013012275U1 (de) | 2013-04-23 | 2015-12-18 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Kit zum Herstellen eines vernetzten Gels zum Umschließen von Nierensteinen und/oder Nierensteinfragmenten |
| JP7215905B2 (ja) * | 2016-03-18 | 2023-01-31 | プレシゲン，インコーポレイテッド | Ｖｉｉ型コラーゲン欠損症の治療のための組成物及び方法 |
| DE102017220710A1 (de) * | 2017-11-20 | 2019-05-23 | Aesculap Ag | Implantat und Kit zum Behandeln und/oder biologischen Rekonstruieren eines Knochendefekts |
| US11767498B2 (en) * | 2019-08-28 | 2023-09-26 | Massachusetts Institute Of Technology | In vitro tissue plate |
| US20250049982A1 (en) | 2021-12-17 | 2025-02-13 | Medskin Solutions Dr. Suwelack Ag | Composition comprising a biomaterial-based porous material coated with a powder |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4352883A (en) * | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
| US4352833A (en) * | 1979-12-12 | 1982-10-05 | Young, Prussin, Mgk, J.V. | Adherent controlled release pesticides |
| EP0127989A3 (en) | 1983-06-01 | 1986-03-26 | Connaught Laboratories Limited | Microencapsulation of living tissue and cells |
| JPS60258121A (ja) * | 1984-05-24 | 1985-12-20 | コノート ラボラトリーズ リミテツド | 生きた組織や細胞のマイクロカプセル及びその製造方法 |
| US5573934A (en) * | 1992-04-20 | 1996-11-12 | Board Of Regents, The University Of Texas System | Gels for encapsulation of biological materials |
| US5908623A (en) * | 1993-08-12 | 1999-06-01 | Cytotherapeutics, Inc. | Compositions and methods for the delivery of biologically active molecules using genetically altered cells contained in biocompatible immunoisolatory capsules |
| US6875856B2 (en) * | 1993-09-24 | 2005-04-05 | Syntro Corporation | Recombinant infectious laryngotracheitis virus and uses thereof |
| CA2214088A1 (en) * | 1995-03-03 | 1996-09-12 | Metabolex Inc. | Novel encapsulation process by a gelling polymer |
| ATE309000T1 (de) * | 1995-06-27 | 2005-11-15 | Bavarian Nordic As | Verkapselte zellen die virenpartikeln produzieren |
| US5888497A (en) * | 1996-04-03 | 1999-03-30 | The Rogosin Institute | Agarose coated agarose beads containing cancer cells that produce material which suppresses cancer cell proliferation |
| EP1276859B1 (en) * | 2000-04-28 | 2007-02-07 | Sangamo Biosciences Inc. | Targeted modification of chromatin structure |
| US7780993B2 (en) * | 2001-09-07 | 2010-08-24 | Yeda Research And Development Co. Ltd. | Therapeutic transplantation using developing, human or porcine, renal or hepatic, grafts |
| JP2006516134A (ja) * | 2002-12-24 | 2006-06-22 | アン−ゴ−ゲン・インコーポレイテッド | 封入化細胞療法 |
| ITMI20032115A1 (it) * | 2003-11-03 | 2005-05-04 | Uni Degli Dustdi Di Pavia | Allestimento di sistemi di coltura tridimensionale in |
| EP2228035A1 (en) * | 2003-12-23 | 2010-09-15 | FMC Biopolymer AS | Use of alginate matrices to control cell growth |
| CN101903049B (zh) | 2007-12-20 | 2014-08-13 | 伊西康公司 | 包囊的肾组织 |
| US8734257B2 (en) * | 2011-09-30 | 2014-05-27 | Igt | Wager gaming voting leaderboard |
-
2008
- 2008-12-17 CN CN200880121614.8A patent/CN101903049B/zh not_active Expired - Fee Related
- 2008-12-17 EP EP08868202.6A patent/EP2231209B1/en not_active Not-in-force
- 2008-12-17 CA CA2708959A patent/CA2708959C/en active Active
- 2008-12-17 BR BRPI0821540-5A patent/BRPI0821540B1/pt not_active IP Right Cessation
- 2008-12-17 PL PL08868202T patent/PL2231209T3/pl unknown
- 2008-12-17 AU AU2008343193A patent/AU2008343193B2/en not_active Ceased
- 2008-12-17 WO PCT/US2008/087211 patent/WO2009085850A2/en not_active Ceased
- 2008-12-17 JP JP2010539742A patent/JP5456692B2/ja not_active Expired - Fee Related
- 2008-12-17 US US12/337,413 patent/US8734527B2/en not_active Expired - Fee Related
-
2014
- 2014-04-14 US US14/252,132 patent/US9579348B2/en not_active Expired - Fee Related
- 2014-05-16 US US14/279,831 patent/US20140248326A1/en not_active Abandoned
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