JP2011507599A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2011507599A5 JP2011507599A5 JP2010539515A JP2010539515A JP2011507599A5 JP 2011507599 A5 JP2011507599 A5 JP 2011507599A5 JP 2010539515 A JP2010539515 A JP 2010539515A JP 2010539515 A JP2010539515 A JP 2010539515A JP 2011507599 A5 JP2011507599 A5 JP 2011507599A5
- Authority
- JP
- Japan
- Prior art keywords
- medical device
- connexin
- compound
- item
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000001875 compounds Chemical class 0.000 claims description 31
- 239000003795 chemical substances by application Substances 0.000 claims description 28
- 238000002513 implantation Methods 0.000 claims description 15
- 239000000203 mixture Substances 0.000 claims description 15
- 230000006378 damage Effects 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 13
- 241000124008 Mammalia Species 0.000 claims description 12
- 239000011248 coating agent Substances 0.000 claims description 12
- 238000000576 coating method Methods 0.000 claims description 12
- 238000003780 insertion Methods 0.000 claims description 12
- 230000037431 insertion Effects 0.000 claims description 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 12
- 241001465754 Metazoa Species 0.000 claims description 10
- 239000007943 implant Substances 0.000 claims description 8
- 210000001519 tissue Anatomy 0.000 claims description 8
- 102000001045 Connexin 43 Human genes 0.000 claims description 6
- 108010069241 Connexin 43 Proteins 0.000 claims description 6
- 108091034117 Oligonucleotide Proteins 0.000 claims description 6
- 108091033319 polynucleotide Proteins 0.000 claims description 6
- 102000040430 polynucleotide Human genes 0.000 claims description 6
- 239000002157 polynucleotide Substances 0.000 claims description 6
- 230000002792 vascular Effects 0.000 claims description 6
- 208000027418 Wounds and injury Diseases 0.000 claims description 5
- 230000001668 ameliorated effect Effects 0.000 claims description 5
- 208000014674 injury Diseases 0.000 claims description 5
- 239000012634 fragment Substances 0.000 claims description 4
- 229920000642 polymer Polymers 0.000 claims description 4
- 150000003839 salts Chemical class 0.000 claims description 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims description 2
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 claims description 2
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 claims description 2
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims description 2
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims description 2
- 108091030071 RNAI Proteins 0.000 claims description 2
- 108020004459 Small interfering RNA Proteins 0.000 claims description 2
- 230000003872 anastomosis Effects 0.000 claims description 2
- 239000000074 antisense oligonucleotide Substances 0.000 claims description 2
- 238000012230 antisense oligonucleotides Methods 0.000 claims description 2
- 230000004888 barrier function Effects 0.000 claims description 2
- 210000000988 bone and bone Anatomy 0.000 claims description 2
- 239000000316 bone substitute Substances 0.000 claims description 2
- 230000000747 cardiac effect Effects 0.000 claims description 2
- 238000007598 dipping method Methods 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims description 2
- 230000009368 gene silencing by RNA Effects 0.000 claims description 2
- 210000005003 heart tissue Anatomy 0.000 claims description 2
- 210000003709 heart valve Anatomy 0.000 claims description 2
- 230000002439 hemostatic effect Effects 0.000 claims description 2
- 244000144972 livestock Species 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 108020004999 messenger RNA Proteins 0.000 claims description 2
- 230000000399 orthopedic effect Effects 0.000 claims description 2
- 239000000816 peptidomimetic Substances 0.000 claims description 2
- 229920001184 polypeptide Polymers 0.000 claims description 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 2
- 239000000126 substance Substances 0.000 claims description 2
- 229940124597 therapeutic agent Drugs 0.000 claims description 2
- 230000002265 prevention Effects 0.000 claims 2
- 238000013268 sustained release Methods 0.000 claims 1
- 239000012730 sustained-release form Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US873807P | 2007-12-21 | 2007-12-21 | |
| PCT/US2008/014023 WO2009085272A2 (en) | 2007-12-21 | 2008-12-22 | Improved medical devices |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014187605A Division JP2015006440A (ja) | 2007-12-21 | 2014-09-16 | 改良医療デバイス |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011507599A JP2011507599A (ja) | 2011-03-10 |
| JP2011507599A5 true JP2011507599A5 (enExample) | 2013-04-25 |
Family
ID=40466841
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010539515A Pending JP2011507599A (ja) | 2007-12-21 | 2008-12-22 | 改良医療デバイス |
| JP2014187605A Withdrawn JP2015006440A (ja) | 2007-12-21 | 2014-09-16 | 改良医療デバイス |
| JP2016213448A Withdrawn JP2017064431A (ja) | 2007-12-21 | 2016-10-31 | 改良医療デバイス |
| JP2018146805A Pending JP2018198954A (ja) | 2007-12-21 | 2018-08-03 | 改良医療デバイス |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014187605A Withdrawn JP2015006440A (ja) | 2007-12-21 | 2014-09-16 | 改良医療デバイス |
| JP2016213448A Withdrawn JP2017064431A (ja) | 2007-12-21 | 2016-10-31 | 改良医療デバイス |
| JP2018146805A Pending JP2018198954A (ja) | 2007-12-21 | 2018-08-03 | 改良医療デバイス |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US9035037B2 (enExample) |
| EP (1) | EP2234656A2 (enExample) |
| JP (4) | JP2011507599A (enExample) |
| AU (1) | AU2008343843A1 (enExample) |
| CA (1) | CA2710386A1 (enExample) |
| WO (1) | WO2009085272A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2662088A3 (en) | 2005-02-03 | 2014-02-19 | Coda Therapeutics Limited | Anti-connexin compounds and uses thereof |
| US8975237B2 (en) | 2007-12-21 | 2015-03-10 | Coda Therapeutics, Inc. | Treatment of fibrotic conditions |
| US9446031B2 (en) | 2012-01-18 | 2016-09-20 | National University Of Singapore | Compositions and methods for neovascularization |
| CN104271142B (zh) | 2012-03-01 | 2017-07-04 | 福斯特斯特林研究公司 | 含有α连接蛋白C‑末端(ACT)肽的局部凝胶 |
| JP6683686B2 (ja) | 2014-08-22 | 2020-04-22 | オークランド ユニサービシーズ リミティド | チャネル調節剤 |
| CN105498074B (zh) * | 2015-12-25 | 2017-08-08 | 李雷 | 血管壁修复系统 |
| US20180028468A1 (en) * | 2016-04-29 | 2018-02-01 | Ocunexus Therapeutics, Inc. | Sustained release drug delivery devices |
| RU2636418C1 (ru) * | 2017-03-16 | 2017-11-23 | Дмитрий Викторович Давыдов | Способ коррекции экзофтальма и имплантат для увеличения объема орбиты в области сформированного костного дефекта при коррекции экзофтальма |
| WO2018199777A1 (en) | 2017-04-28 | 2018-11-01 | Auckland Uniservices Limited | Methods of treatment and novel constructs |
| EP3746393A4 (en) | 2018-02-02 | 2021-11-03 | Galen Therapeutics Llc | DEVICE AND METHOD FOR PROTECTING NEURONS AND REDUCING INFLAMMATION AND SCARING |
| EP4232157A4 (en) | 2020-10-22 | 2024-08-28 | Xequel Bio, Inc. | PEPTIDE FORMULATIONS AND ASSOCIATED OPHTHALMIC USES |
| US20250289864A1 (en) * | 2022-05-13 | 2025-09-18 | University Of Utah Research Foundation | Gja1-20k to limited cardiac arrhythmias |
| US20240299440A1 (en) * | 2023-03-07 | 2024-09-12 | Amber Ophthalmics, Inc. | Novel treatments for ocular disorders |
Family Cites Families (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1322714C (en) | 1986-11-14 | 1993-10-05 | Harry N. Antoniades | Wound healing and bone regeneration |
| US4916193A (en) | 1987-12-17 | 1990-04-10 | Allied-Signal Inc. | Medical devices fabricated totally or in part from copolymers of recurring units derived from cyclic carbonates and lactides |
| US5092877A (en) | 1988-09-01 | 1992-03-03 | Corvita Corporation | Radially expandable endoprosthesis |
| US5004810A (en) | 1988-09-30 | 1991-04-02 | Schering Corporation | Antiviral oligomers |
| US4994071A (en) | 1989-05-22 | 1991-02-19 | Cordis Corporation | Bifurcating stent apparatus and method |
| US5304121A (en) | 1990-12-28 | 1994-04-19 | Boston Scientific Corporation | Drug delivery system making use of a hydrogel polymer coating |
| US5166195A (en) | 1990-05-11 | 1992-11-24 | Isis Pharmaceuticals, Inc. | Antisense inhibitors of the human immunodeficiency virus phosphorothioate oligonucleotides |
| US5163952A (en) | 1990-09-14 | 1992-11-17 | Michael Froix | Expandable polymeric stent with memory and delivery apparatus and method |
| US5599352A (en) | 1992-03-19 | 1997-02-04 | Medtronic, Inc. | Method of making a drug eluting stent |
| GB9206861D0 (en) | 1992-03-28 | 1992-05-13 | Univ Manchester | Wound healing and treatment of fibrotic disorders |
| US5464650A (en) | 1993-04-26 | 1995-11-07 | Medtronic, Inc. | Intravascular stent and method |
| US5857998A (en) | 1994-06-30 | 1999-01-12 | Boston Scientific Corporation | Stent and therapeutic delivery system |
| US5837313A (en) | 1995-04-19 | 1998-11-17 | Schneider (Usa) Inc | Drug release stent coating process |
| US6566339B1 (en) | 1995-08-04 | 2003-05-20 | Renovo Limited | Pharmaceutical composition |
| GB2304047A (en) | 1995-08-09 | 1997-03-12 | Univ Manchester | Pharmaceutical compositions containing cytokines |
| ES2293137T3 (es) | 1995-10-11 | 2008-03-16 | Novartis Vaccines And Diagnostics, Inc. | Combinacion de pdgf, kgf,igf e igfbp para curacion de heridas. |
| EP0930876B2 (en) | 1996-07-22 | 2010-07-07 | Renovo Limited | Use of compounds that promote oestrogenic activity for acclerating the healing of skin wounds |
| GB9702943D0 (en) | 1997-02-13 | 1997-04-02 | Univ Manchester | Wound healing |
| US6273913B1 (en) | 1997-04-18 | 2001-08-14 | Cordis Corporation | Modified stent useful for delivery of drugs along stent strut |
| US6855505B2 (en) | 1998-06-26 | 2005-02-15 | Renovo Limited | Method for quantifying TGF-β |
| AU766826B2 (en) | 1998-07-30 | 2003-10-23 | Government of The United States of America, as represented by The Secretary Department of Health & Human Services, The National Institutes of Health, The | Thymosin beta4 promotes wound repair |
| DE19902481A1 (de) * | 1999-01-22 | 2000-07-27 | Signus Medizintechnik Gmbh | Wirbelsäulenersatzkörper |
| CA2361251C (en) | 1999-01-27 | 2011-03-08 | David L. Becker | Formulations comprising antisense nucleotides to connexins |
| GB9903598D0 (en) | 1999-02-18 | 1999-04-07 | Univ Manchester | Connective tissue healing |
| US6251136B1 (en) | 1999-12-08 | 2001-06-26 | Advanced Cardiovascular Systems, Inc. | Method of layering a three-coated stent using pharmacological and polymeric agents |
| US7250397B2 (en) | 2000-02-23 | 2007-07-31 | Zealand Pharma A/S | Antiarrhythmic peptides |
| JP2005509621A (ja) | 2001-10-17 | 2005-04-14 | ユニバーシティ オブ ウェールズ カレッジ オブ メディスン | ギャップ結合ならびにｅｄｈｆ |
| CN1939529A (zh) | 2002-01-29 | 2007-04-04 | Wyeth公司 | 用于调节连接蛋白半通道的组合物和方法 |
| US6702850B1 (en) | 2002-09-30 | 2004-03-09 | Mediplex Corporation Korea | Multi-coated drug-eluting stent for antithrombosis and antirestenosis |
| JP5838017B2 (ja) * | 2003-12-03 | 2015-12-24 | コーダ セラピューティクス， インコーポレイテッド | コネキシンに対して標的化されたアンチセンス化合物およびその使用方法 |
| HUE038099T2 (hu) | 2004-12-21 | 2018-09-28 | Musc Found For Res Dev | Kompozíciók és módszerek sebgyógyulás és szöveti regeneráció elõsegítésére |
| US7829527B2 (en) * | 2005-02-02 | 2010-11-09 | University Of Vermont And State Agricultural College | Emergence of a R-type Ca2+ channel (Cav 2.3) contributes to cerebral artery constriction following subarachnoid hemorrhage |
| EP2662088A3 (en) | 2005-02-03 | 2014-02-19 | Coda Therapeutics Limited | Anti-connexin compounds and uses thereof |
| AU2008335718A1 (en) | 2007-12-11 | 2009-06-18 | Coda Therapeutics, Inc. | Impaired wound healing compositions and treatments |
-
2008
- 2008-12-22 EP EP08867503A patent/EP2234656A2/en not_active Ceased
- 2008-12-22 WO PCT/US2008/014023 patent/WO2009085272A2/en not_active Ceased
- 2008-12-22 CA CA2710386A patent/CA2710386A1/en not_active Abandoned
- 2008-12-22 US US12/809,941 patent/US9035037B2/en not_active Expired - Fee Related
- 2008-12-22 JP JP2010539515A patent/JP2011507599A/ja active Pending
- 2008-12-22 AU AU2008343843A patent/AU2008343843A1/en not_active Abandoned
-
2014
- 2014-09-16 JP JP2014187605A patent/JP2015006440A/ja not_active Withdrawn
-
2015
- 2015-05-18 US US14/715,282 patent/US9561311B2/en active Active
-
2016
- 2016-10-31 JP JP2016213448A patent/JP2017064431A/ja not_active Withdrawn
-
2017
- 2017-02-03 US US15/424,758 patent/US10251929B2/en not_active Expired - Fee Related
-
2018
- 2018-08-03 JP JP2018146805A patent/JP2018198954A/ja active Pending
-
2019
- 2019-04-08 US US16/378,402 patent/US20190290719A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Parent et al. | Design of calcium phosphate ceramics for drug delivery applications in bone diseases: A review of the parameters affecting the loading and release of the therapeutic substance | |
| ES2848562T3 (es) | Procedimiento indirecto para reparación de tejido articular | |
| JP5114801B2 (ja) | 生体吸収性支持フレームを有するグラフト | |
| CN102231992B (zh) | 用于治疗肌腱和韧带损伤的血小板衍生生长因子的组合物和方法 | |
| US9585988B2 (en) | Anchorage devices comprising an active pharmaceutical ingredient | |
| JP6889193B2 (ja) | 再狭窄の予防または治療のための化合物および方法 | |
| US20050202061A1 (en) | Optimized dosing for drug coated stents | |
| EP1723976A3 (en) | Intraluminal medical devices in combination with therapeutic agents | |
| JP5153340B2 (ja) | 薬剤放出制御組成物および薬剤放出性医療器具 | |
| US20150273119A1 (en) | Formulation comprising anti-scarring agents and biocompatible polymers for medical device coating | |
| EP3056229A3 (en) | The local administration of a combination of rapamycin and 17 beta-estradiol for the treatment of vulnerable plaque | |
| JP2018198954A (ja) | 改良医療デバイス | |
| MX2010007571A (es) | Endoprotesis eluyente con receptaculo de rapamicina. | |
| ES2987568T3 (es) | Cuerda de terapia de inserción de hilo y aparato de aguja de terapia de inserción de hilo que comprende la misma | |
| DE602005022378D1 (de) | Lokale, vaskuläre Verabreichung von 2-methoxyestradiol in Kombination mit Rapamycin zur Vorbeugung von Restenose nach Gefässverletzungen | |
| Chou et al. | Combination of a biodegradable three-dimensional (3D)–printed cage for mechanical support and nanofibrous membranes for sustainable release of antimicrobial agents for treating the femoral metaphyseal comminuted fracture | |
| ATE475438T1 (de) | Lokale, vaskuläre verabreichung von etoposide in kombination mit rapamycin zur vorbeugung von restenose nach gefässverletzungen | |
| JP2011507859A5 (enExample) | ||
| WO2011031301A2 (en) | Intrapericardial delivery of periostin | |
| US20070129790A1 (en) | Treatment of aneurysms with an implantable polymeric, biodegradable device incorporating a MMP inhibitor | |
| JP2024532867A5 (enExample) | ||
| Kusanagi et al. | Hydrogel-mediated release of basic fibroblast growth factor from a stent-graft accelerates biological fixation with the aortic wall in a porcine model | |
| JP2002512951A5 (enExample) | ||
| Ward et al. | Strategies to overcome biological barriers to biosensing | |
| McMaster | Ex-vivo Evaluation of a Modified Teno Fix® Device Repair Pattern Versus a Three-Loop Pulley for Repair of Equine Flexor Tendons |