JP2011502521A5 - - Google Patents

Info

Publication number

JP2011502521A5

JP2011502521A5 JP2010533337A JP2010533337A JP2011502521A5 JP 2011502521 A5 JP2011502521 A5 JP 2011502521A5 JP 2010533337 A JP2010533337 A JP 2010533337A JP 2010533337 A JP2010533337 A JP 2010533337A JP 2011502521 A5 JP2011502521 A5 JP 2011502521A5

Authority

JP

Japan

Prior art keywords

polypeptide

fusion polypeptide

fusion

oligomeric

seq

Prior art date

2008-11-12

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
• Discuss

• 108090000765 processed proteins & peptides Proteins 0.000 claims 32
• 229920001184 polypeptide Polymers 0.000 claims 31
• 102000004196 processed proteins & peptides Human genes 0.000 claims 31
• 230000004927 fusion Effects 0.000 claims 16
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
• 239000013638 trimer Substances 0.000 claims 3
• 230000002163 immunogen Effects 0.000 claims 2
• 102000039446 nucleic acids Human genes 0.000 claims 2
• 108020004707 nucleic acids Proteins 0.000 claims 2
• 150000007523 nucleic acids Chemical class 0.000 claims 2
• 239000002773 nucleotide Substances 0.000 claims 2
• 125000003729 nucleotide group Chemical group 0.000 claims 2
• 241000713772 Human immunodeficiency virus 1 Species 0.000 claims 1
• 239000002671 adjuvant Substances 0.000 claims 1
• 125000003275 alpha amino acid group Chemical group 0.000 claims 1
• 239000000427 antigen Substances 0.000 claims 1
• 102000036639 antigens Human genes 0.000 claims 1
• 108091007433 antigens Proteins 0.000 claims 1
• 238000003776 cleavage reaction Methods 0.000 claims 1
• 239000003937 drug carrier Substances 0.000 claims 1
• 239000012634 fragment Substances 0.000 claims 1
• 230000001939 inductive effect Effects 0.000 claims 1
• 230000003472 neutralizing effect Effects 0.000 claims 1
• 230000007017 scission Effects 0.000 claims 1