JP2011232290A5 - - Google Patents
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- JP2011232290A5 JP2011232290A5 JP2010105300A JP2010105300A JP2011232290A5 JP 2011232290 A5 JP2011232290 A5 JP 2011232290A5 JP 2010105300 A JP2010105300 A JP 2010105300A JP 2010105300 A JP2010105300 A JP 2010105300A JP 2011232290 A5 JP2011232290 A5 JP 2011232290A5
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- stratum corneum
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皮膚は、表皮、真皮及び皮下組織の３層から構成されている。さらに、表皮は角層、顆粒層、有棘層及び基底層の４層から構成され、外気と接している角層は、水分保持機能やバリア機能という極めて重要な役割を果たしている。かような重要な機能を有する角層（以下において、角層を構成している１〜数十枚の角層細胞も含む意味である）の成分を計測評価することは、極めて重要視された課題であった。皮膚成分の測定に関しては、既に近赤外線を用いて皮膚水分濃度を計測する技術（例えば、特許文献１参照）、ラマンスペクトルを用いた皮膚水分量を計測する技術（例えば、特許文献２参照）、第２高調波発生光（ＳＨＧ光）を用いて真皮等の皮膚内部の変化に起因する皮膚のしわの状態を計測する技術（例えば、特許文献３参照）等の非侵襲的光学的技術が開示されている。しかし、角層に対しては、かような技術は全く知られていなかった。 The skin is composed of three layers: epidermis, dermis and subcutaneous tissue. Furthermore, the epidermis is composed of four layers, a stratum corneum, a granule layer, a spiny layer, and a basal layer, and the stratum corneum in contact with the outside air plays an extremely important role of a moisture retention function and a barrier function. It was extremely important to measure and evaluate the components of the stratum corneum having such an important function (hereinafter, including 1 to several tens of stratum corneum cells constituting the stratum corneum). It was a challenge. Regarding the measurement of skin components, a technique for measuring skin moisture concentration using near infrared rays (for example, see Patent Document 1), a technique for measuring skin moisture content using a Raman spectrum (for example, see Patent Document 2), Noninvasive optical techniques such as a technique (for example, see Patent Document 3) that measures the wrinkle state of the skin caused by changes in the skin such as the dermis using second harmonic generation light (SHG light) are disclosed. Has been. However, no such technique has been known for the stratum corneum.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010105300A JP2011232290A (en) | 2010-04-30 | 2010-04-30 | Skin horny layer component measurement method using terahertz wave |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2010105300A JP2011232290A (en) | 2010-04-30 | 2010-04-30 | Skin horny layer component measurement method using terahertz wave |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2011232290A JP2011232290A (en) | 2011-11-17 |
| JP2011232290A5 true JP2011232290A5 (en) | 2013-05-16 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010105300A Pending JP2011232290A (en) | 2010-04-30 | 2010-04-30 | Skin horny layer component measurement method using terahertz wave |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2011232290A (en) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5945142B2 (en) * | 2012-03-27 | 2016-07-05 | 株式会社 資生堂 | How to evaluate cosmetics for wrinkle improvement |
| JP6454498B2 (en) * | 2014-09-03 | 2019-01-16 | 国立大学法人京都大学 | Method for measuring skin stratum corneum moisture content using terahertz waves |
| JP6331140B2 (en) * | 2014-09-03 | 2018-05-30 | 国立大学法人京都大学 | Moisture content measurement method |
| CN105404228B (en) * | 2015-12-24 | 2017-12-26 | 北京农业智能装备技术研究中心 | A kind of Terahertz experimental system and method |
| JP6781424B2 (en) * | 2016-05-05 | 2020-11-04 | 国立大学法人京都大学 | Method of measuring skin stratum corneum water content using terahertz waves |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2008185552A (en) * | 2007-01-31 | 2008-08-14 | Tohoku Univ | Measuring instrument and measuring method |
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2010
- 2010-04-30 JP JP2010105300A patent/JP2011232290A/en active Pending
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