JP2011185729A - Automatic analysis device - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To prevent an infection disease due to a needlestick, and efficiently implement analysis by an infrared sensor for monitoring an area in the vicinity of a probe in which a hand of a user enters. <P>SOLUTION: An automatic analysis device is provided for dispensing a sample and a reagent to a reaction container, and for measuring a mixed liquid. The device has: a sample probe for dispensing the sample to the reaction container; a reagent probe for dispensing the reagent to the reaction container; a probe mover for moving the sample probe and the reagent probe; an intrusion sensor for detecting an intrusion of an object into the monitored area based on an infrared ray; and a controller for deactivating the movement of the sample probe or the reagent probe by the probe mover in response to a detection of the intrusion of the object by the intrusion sensor. <P>COPYRIGHT: (C)2011,JPO&INPIT

Description

  The present invention relates to an automatic analyzer that can detect intrusion of a human body into an automatic analyzer.

  The automated analyzer mixes and reacts test samples such as blood and urine collected from the sample (hereinafter simply referred to as samples) and reagents, and examines the reaction state with light to analyze the components of the sample. It is a device that performs automatically. This automatic analyzer is widely used in hospitals and laboratories because it can perform analysis on various analysis items for a large number of samples.

  When mixing a sample and a reagent in an automatic analyzer, a hollow needle called a probe draws a specified amount of the sample or reagent from the sample container or reagent container, and discharges and moves it to a container called a reaction tube (Hereinafter, sampling and discharging operations are referred to as dispensing). Since the probe moves around between the sample container or reagent container and the reaction tube during dispensing, the probe that moves when a hand is inserted in the vicinity of the automatic analyzer sticks into the hand, and samples attached to the probe cause infections. May occur. In order to prevent the needle stick of the probe, an invention has been disclosed in which an imaging camera is provided on the cover of the automatic analyzer and the operation of the automatic analyzer is stopped when an object that enters the imaging range is detected (for example, Patent Document 1). reference.).

JP 2007-303885 A

  The operator of the automatic analyzer as described above performs an operation of replacing the sample container and the reagent container with another container or an operation of moving the container using a jig as necessary. The spare container or jig used by the operator may be placed near the probe of the automatic analyzer for convenience of operation. When the object detection by the photographing camera as described above is used, the operation of the automatic analyzer stops in response to the placement of another container or jig. By detecting objects other than the human body that are not at risk of infectious diseases and stopping the operation of the automatic analyzer, the sample being analyzed is discarded each time the operation is stopped, and efficient analysis cannot be performed. there were.

  Therefore, an object of the present invention is to prevent infectious diseases caused by needle sticks and perform efficient analysis by monitoring the vicinity of a probe into which a human body can invade with an intrusion detection sensor.

  In order to solve the above-described problems, an automatic analyzer according to the present invention includes a sample probe for dispensing a sample and a reagent into a reaction container and measuring the mixed solution, and a sample probe for dispensing the sample into the reaction container. A reagent probe for dispensing the reagent into the reaction vessel, a probe moving means for moving the sample probe and the reagent probe, an intrusion sensor for detecting that an object has entered the monitoring region based on infrared rays, Control means for stopping the movement of the sample probe or the reagent probe by the probe moving means when the intrusion sensor detects the intrusion of an object.

  According to the present invention, an intrusion detection sensor monitors a region in the vicinity of a probe that a user's hand can enter. Thereby, it is possible to prevent infection due to needle stick and to perform efficient analysis.

The block diagram which shows the internal structure of the automatic analyzer which concerns on embodiment of this invention. 1 is an external perspective view showing a configuration of an automatic analyzer according to an embodiment of the present invention. 1 is an external perspective view showing a configuration of an intrusion detection sensor according to an embodiment of the present invention. The top view of the automatic analyzer which shows the detection range of the intrusion detection sensor which concerns on embodiment of this invention. The flowchart which shows control of the intrusion detection of the automatic analyzer which concerns on embodiment of this invention. The figure which shows the example of a screen display at the time of the intrusion detection which concerns on embodiment of this invention. The external appearance perspective view which shows the structure of the automatic analyzer which concerns on another embodiment of this invention. The external appearance perspective view which shows the structure of the automatic analyzer which concerns on another embodiment of this invention.

  Embodiments of the present invention will be described below with reference to the drawings.

(Internal configuration of automatic analyzer 1)
FIG. 1 is a block diagram showing a configuration of an automatic analyzer 1 according to the present invention.

  As shown in FIG. 1, the automatic analyzer 1 according to the present invention includes an intrusion detection sensor 11, a sample unit 21, a reagent unit 22, a reaction unit 23, a mechanism unit control unit 31, a calculation unit 41, The storage unit 42, the display unit 52, the operation unit 60, and the system control unit 70 are configured. Note that the configuration of the present invention is not limited to this, and appropriate components may be added or omitted.

  The system control unit 70 includes a CPU (Central Processing Unit), a ROM (Read Only Memory), a RAM (Random Access Memory), and the like. The system control unit 70 executes processing according to various application programs loaded in the ROM and RAM in accordance with an instruction signal input from the operation unit 71 described later. The system control unit 70 performs overall control of the automatic analyzer 1 by processing signals supplied from the respective units and generating various control signals and supplying them to the respective units.

  The operation unit 71 includes, for example, a touch panel display and mechanical buttons, and receives an input made by the user of the automatic analyzer 1 with respect to the operation unit 71. The operation unit 71 outputs an instruction signal to the system control unit 70 in response to a user input.

  Next, the configurations of the intrusion detection sensors 111 and 112, the sample unit 21, the reagent unit 22, and the reaction unit 23 will be described with reference to FIG. FIG. 2 is an external perspective view showing the external appearance of the automatic analyzer 1.

  The intrusion detection sensors 111 and 112 are sensors that detect an object entering the vicinity of the monitoring area and output a detection result. The intrusion detection sensor 111 is provided above the sample probe 211, and the intrusion detection sensor 112 is provided above the first reagent probe 221, and detects and detects a hand entering the vicinity of the sample probe 211 and the first reagent probe 221. Output a signal. The intrusion detection sensors 111 and 112 can be configured using, for example, a pyroelectric infrared sensor. The pyroelectric infrared sensor is a sensor that detects infrared rays emitted from an object. The pyroelectric infrared sensor detects infrared rays having a specific wavelength emitted from an object having temperature, converts the detection result into an electrical signal, and outputs the electrical signal. For example, when the intrusion detection sensors 111 and 112 are configured using pyroelectric infrared sensors, if a human body such as an operator's hand enters the vicinity of the monitoring area of the intrusion detection sensors 111 and 112, the intrusion detection sensors 111 and 112 The detection signal is output to the system control unit 70 in response to the temperature of the.

  The sensors constituting the intrusion detection sensors 111 and 112 may be any sensors that detect the temperature of an object, and are not limited to the illustrated pyroelectric infrared sensors. For example, the intrusion detection sensors 111 and 112 may be configured using various sensors such as a thermal expansion type infrared sensor, a thermocouple type infrared sensor, and a resistance change type (bolometer type) infrared sensor.

  The sample unit 21 includes a sample probe 211, a sample disk 212, sample containers 213 and 215, a sample rack 214, a sample transport rail 216, and a sample suction notch 217 shown in FIG.

  The sample probe 211 sucks a specified amount of sample from the sample containers 213 and 215, and discharges the sample into a reaction cell 232 described later (hereinafter, suction and discharge operations are described as dispensing). It is a needle. A motor (not shown) is attached to the sample probe 211, and its position is moved according to the instruction signal output from the mechanism control unit 31. Specifically, when a sample is aspirated from the sample container 213, the mechanism control unit 31 drives the motor to rotate the sample probe 211 around the installation shaft, and the tip of the sample probe 211 is placed above the sample disk 213. To move. When the tip of the sample probe 211 moves to the upper part of the sample disk 213, the mechanism control unit 31 rotates the sample disk to move the sample container 213 containing a desired sample so as to come to the lower part of the sample probe 211. When the sample container 213 moves, the mechanism control unit 31 drives the motor to lower the sample probe 211 and moves the tip of the sample probe 211 into the sample container 213. When the tip of the sample probe 211 moves to the inside of the sample container 213, the mechanism control unit 31 drives a pump (not shown) provided in the sample probe 211 so that the sample stored in the sample container 213 is transferred to the sample probe 211. Aspirate inside. When the sample probe 211 sucks the sample, the mechanism control unit 31 drives the motor to raise the sample probe 211, and further, centering on the installation shaft so that the tip of the sample probe 211 comes to the upper part of the desired reaction cell 232. The sample probe 211 is rotated. When the sample probe 211 moves to the upper part of the reaction cell 232, the mechanism control unit 31 lowers the sample probe 211 and moves its tip into the reaction cell 232. When the tip of the sample probe 211 enters the reaction cell 232, the mechanism control unit 31 drives a pump (not shown) to discharge the sample stored in the sample probe 211 into the reaction cell 232. By such a series of operations, the sample probe 211 dispenses a desired sample in the sample container 213 into the reaction cell 232. Note that the sample probe 211 performs the same operation when dispensing the sample in the sample container 215. When dispensing the sample in the sample container 215, the mechanism control unit 31 moves the sample probe 211 to the upper part of the sample suction notch 217 and further lowers the sample probe 211 into the sample container 215. Let When the sample probe 211 sucks the sample, the mechanism control unit 31 moves the sample probe 211 into the reaction cell 232 and discharges the sample accommodated in the sample probe 211 into the reaction cell 232.

  The sample disk 212 is a cylindrical container that accommodates the sample container 213. A rotation motor (not shown) is attached to the sample disk 212 and rotates in accordance with a drive signal output from the mechanism control unit 31. As the sample disk 212 rotates, the sample container 213 containing the sample to be dispensed by the sample probe 211 is moved to the suction position of the sample probe 211.

  The sample container 213 is a container for storing a sample such as blood or urine collected from a subject. The sample container 213 accommodated in the sample disk 212 stores, for example, a sample that needs to be analyzed urgently, a calibration sample for setting a reference value for analysis of the reaction unit 23 described later, and the like.

  The sample rack 214 is a container that accommodates the sample container 215. The sample rack 214 is placed on a transport rail 216 described later, and moves in the left-right direction in FIG. 2 by driving the transport rail 216. A sample container 213 accommodated in the sample rack 214 stores a sample of a subject to be analyzed.

  The transport rail 216 is a rail for moving the sample rack 214. A motor (not shown) is attached to the transport rail 216 and moves the sample rack 214 in the left-right direction in FIG. 2 in accordance with a drive signal output from the mechanism control unit 31.

  The transport rail cover 2 is a flat plate attached to the upper part of the transport rail 216. The transport rail cover 2 covers the upper surface of the sample container 215 and prevents foreign matter from entering the sample container 215 and contacting the sample container 215 with an object. The transport rail cover 2 is provided with a notch 217 for sample suction. The sample suction notch 217 is provided so as to be on the circumferential orbit of the sample probe 211. When the sample probe 211 sucks the sample from the sample container 215, the mechanism control unit 31 drives the transport rail 216 to move the desired sample container to the lower part of the sample suction notch 217. Next, the mechanism control unit 31 moves the sample probe 211 to move the tip of the sample probe 211 to the upper part of the sample suction notch 217. When the sample probe 211 moves, the system control unit 70 lowers the sample probe 211 and causes the tip of the sample probe 211 to enter the sample container 215 to perform suction.

  The reagent unit 22 includes a first reagent probe 221, a first reagent disk 222, reagent containers 223 and 226, a second reagent probe 224, and a second reagent disk 225 shown in FIG.

  The first reagent probe 221 is a hollow needle for performing an operation of sucking the reagent from the reagent container 223 accommodated in the first reagent disk 222 and discharging it to the reaction cell 232. A motor (not shown) is attached to the first reagent probe 221 in the same manner as the sample probe 211, and its position is moved according to the instruction signal output by the mechanism control unit 31. The first reagent probe 221 moves between the first reagent disk 222 and the reaction cell 232 to perform dispensing. A circumferential trajectory along which the first reagent probe 221 moves is indicated by a dotted line in FIG.

  The first reagent disk 222 is a cylindrical container that houses the reagent container 223. A rotation motor (not shown) is attached to the first reagent disk 222 and rotates in accordance with a drive signal output by the mechanism control unit 31. By rotating the first reagent disk 222, the reagent container 223 in which the reagent to be dispensed by the first reagent probe 221 is moved to the suction position of the first reagent probe 221.

  The reagent container 223 is a container for storing a reagent for causing a predetermined chemical reaction to the sample. When the automatic analyzer 1 analyzes a sample, first, the sample and the first reagent are mixed to generate a chemical reaction. Then, after a certain time has passed and sufficient reaction has occurred, another chemical reaction is generated by further mixing the second reagent into the mixed solution of the sample and the first reagent. Various first reagents are accommodated in the reagent container 223 accommodated in the first reagent disk 222.

  The second reagent probe 224 is a hollow needle for performing an operation of sucking the reagent from the reagent container 226 accommodated in the second reagent disk 225 and discharging it to the reaction cell 232. The second reagent probe 224 moves between the second reagent disk 225 and the reagent container 226 in accordance with the instruction signal output from the mechanism control unit 31 to perform dispensing. A circumferential trajectory along which the second reagent probe 224 moves is indicated by a dotted line in FIG. The second reagent probe 224 moves its position by driving a motor during dispensing as with other probes, but the second reagent probe 224 is located at the back of the automatic analyzer 1 as shown in FIG. Therefore, the possibility that the human body moves to the vicinity of the second reagent probe 224 is low. Therefore, the intrusion detection sensor 11 is not provided in the second reagent probe 224, and intrusion monitoring is not performed. The configuration of the present invention is not limited to this, and the position of the second reagent probe 224 may be changed to be positioned on the front side of the automatic analyzer 1, and an intrusion detection sensor may be connected to the second reagent probe 224. 11 may be provided.

  The second reagent disk 225 is a cylindrical container that houses the reagent container 226. A rotation motor (not shown) is attached to the second reagent disk 225 and rotates according to a drive signal output from the mechanism control unit 31. As the second reagent disk 225 rotates, the reagent container 226 in which the reagent to be dispensed by the second reagent probe 224 is moved to the lower part of the second reagent probe 224. Various second reagents are stored in the reagent container 226 accommodated in the second reagent disk 225.

  The reaction unit 23 includes a constant temperature bath 231, a reaction cell 232, a light emitting unit and a light receiving unit (not shown) shown in FIG. 2.

  The constant temperature bath 231 is a cylindrical container that accommodates the reaction cell 232. The constant temperature bath 231 is filled with warm water, and the temperature of the reaction cell 232 is kept constant by this warm water. A rotation motor (not shown) is attached to a member that holds the reaction cell 232 in the thermostatic chamber 231 and rotates according to a drive signal output from the mechanism control unit 31. By rotating the member holding the reaction cell 232, the reaction cell 232 that receives the discharge of the sample is moved to the lower part of the sample probe 211, the reaction cell 232 that receives the discharge of the first reagent is moved to the lower part of the first reagent probe 221, and The reaction cells 232 that receive the discharge of the two reagents move to the lower part of the second reagent probe 224, respectively. In the reaction cell 232 accommodated in the thermostatic chamber 231, a mixed solution of the sample, the first reagent, and the second reagent is stored.

  A light emitting unit and a photometric unit are provided on the side surface of the thermostatic chamber 231. The light emitting unit irradiates light toward the mixed liquid in the reaction cell 232. The light receiving unit receives the transmitted light transmitted through the liquid mixture in the reaction cell 232, analyzes the wavelength component of the transmitted light, and acquires wavelength component information. The light receiving unit outputs this wavelength component information to the calculation unit 41.

  The computing unit 41 analyzes a predetermined measurement item for the measured sample based on the wavelength analysis information output from the light receiving unit of the reaction unit 23. When the calculation unit 41 calculates the analysis information, the calculation unit 41 outputs the analysis information to the system control unit 70.

  The storage unit 42 is configured by a storage medium such as an electrically rewritable or erasable HDD (Hard Disk Drive) or a flash memory that is a nonvolatile memory, and stores analysis information output from the calculation unit 42. In addition, the storage unit 42 stores information on a dispensing status indicating which reaction cell 232 has been dispensed. The information on the dispensing status includes information on whether or not the sample, the first reagent, and the second reagent have been discharged to the reaction cell 232, respectively. The system control unit 70 reads out information on the dispensing status from the storage unit 42 and grasps what is being discharged into the reaction cell 232.

  The display unit 52 includes a monitor such as a CRT or a liquid crystal panel, and displays analysis information output from the calculation unit 41. When the intrusion detection sensor 11 detects an intrusion, a warning screen indicating that the analysis operation of the automatic analyzer 1 is stopped is displayed.

(Operation when intrusion detection)
FIG. 3 is an external perspective view showing configurations of the sample probe 211 and the intrusion detection sensor 111. The intrusion detection sensor 11 is provided, for example, on the upper part of the installation shaft of the sample probe 211. The intrusion detection sensor 11 outputs a detection result when detecting an object that enters the monitoring range with the conical region indicated by the solid line in FIG. 3 as the monitoring range. By setting the monitoring range to be larger than the movement range of the sample probe 211, the intrusion detection sensor 111 can detect a human body entering the monitoring range before contacting the sample probe 211. The first reagent probe and the intrusion detection sensor 112 have the same configuration.

  FIG. 4 is an external view of the automatic analyzer 1 as viewed from above. As described above, when performing the dispensing operation, the sample probe 211 rotates and moves so as to pass through the upper part of the sample disk 213, the upper part of the sample suction notch 217, and the upper part of the reaction cell 232. A circular orbit along which the sample probe 211 moves is indicated by a dotted line in FIG. When the human body is in the vicinity of the region indicated by the dotted line in FIG. 4, the moving sample probe 211 may come into contact with the human body and pierce it. Similarly, when the first reagent probe 221 moves between the first reagent disk 222 and the reaction cell 232 for dispensing, the moving first reagent probe 221 may come into contact with and pierce the human body.

  Therefore, in the present invention, the intrusion detection sensors 111 and 112 arranged above the sample probe 211 and the first reagent probe 221 are used to monitor a human body that enters the vicinity of the region indicated by the dotted line. The monitoring range of the intrusion detection sensors 111 and 112 is indicated by hatching in FIG. By setting the monitoring range to be larger than the circumferential trajectory of the sample probe 211 and the first reagent probe 221, the intrusion detection sensors 111 and 112 detect the human body entering the vicinity of the probe before contact, and detect the detection signal. Can be output.

  When the intrusion detection sensors 111 and 112 detect that the human body has entered, the operation of the sample probe 211 or the first reagent probe 221 is stopped to prevent the probe tip from being stuck into the human body. Specifically, when the intrusion detection sensors 111 and 112 detect that a human body has entered the shaded area illustrated in FIG. 4, the intrusion detection sensors 111 and 112 output detection signals to the system control unit 70. The system control unit 70 outputs an instruction signal to the mechanism control unit 31 to stop the operation of the sample probe 211 or the first reagent probe 221. Stopping the probe prevents the tip of the probe from sticking into the human body. It is not necessary to stop both probes at the time of intrusion detection. For example, when the intrusion detection sensor 111 detects intrusion, the operation of the sample probe 211 is stopped, and when the intrusion detection sensor 112 detects intrusion, The operation of the one reagent probe 221 is stopped.

  When the intrusion detection sensors 111 and 112 detect intrusion, the system control unit 70 displays a warning screen 2000 on the display unit 52. FIG. 6 shows a display example of the warning screen 2000. On the warning screen 2000, for example, information indicating which of the intrusion detection sensors 111 and 112 has detected intrusion is displayed in the window 2001. By displaying the window 2001, the operator can grasp the cause of the mechanism control unit 31 stopping the operation.

  By the way, in the analysis of the sample by the automatic analyzer 1, the sample and the first reagent are first mixed to generate a chemical reaction, and after a certain time has passed and a sufficient reaction has occurred, the sample and the first reagent are mixed. It was stated that another chemical reaction is generated by further mixing the second reagent into the mixed solution. When the intrusion detection sensors 111 and 112 detect intrusion during the series of analysis operations and the sample probe 211 and the first reagent probe 221 stop operating, the sample or the first reagent is discharged into the reaction cell 232 at the correct timing. Will not be. In order to prevent a situation in which the sample or the first reagent is discharged to the reaction cell 232 at an inappropriate timing, the reaction cell 232 in which the operation of the mechanism control unit 31 is stopped before the first reagent is discharged in the analysis process will be described later. Without performing the analysis step, the reaction cell 232 is cleaned using a reaction cell cleaning unit (not shown), and the mixed solution in the reaction cell 232 is discarded.

  On the other hand, for the reaction cell 232 in which the discharge of the first reagent has already ended, even when the operation of the sample probe 211 and the first reagent probe 221 is stopped, the discharge of the second reagent, the light emitting unit, and the light receiving unit Continue the analysis operation by. For the reaction cell 232 in which the analysis can be continued, the analysis can be continued without discarding the mixed solution, so that the number of samples to be re-analyzed can be minimized.

  When the intrusion detection sensors 111 and 112 detect intrusion, the system control unit 70 displays the number of the reaction cell 232 to be discarded on the warning screen 2000. FIG. 6 shows a display example of the warning screen 2000. On the warning screen 2000, the number of the reaction cell 232 that needs to be discarded due to intrusion detection prior to the introduction of the first reagent is displayed in the window 2002. By displaying the window 2002, the operator can grasp which sample needs to be measured again.

(Intrusion detection process flow)
FIG. 5 is a flowchart showing the operation of the mechanism control unit 31 when the intrusion detection sensors 111 and 112 detect intrusions. Hereinafter, the intrusion detection process will be described with reference to FIG.

  First, the intrusion detection sensors 111 and 112 monitor whether there is an intruding object within the monitoring range (step 1001). When the intrusion detection sensors 111 and 112 do not detect the intrusion (No in Step 1002), the process returns to Step 1001 and the intrusion detection sensors 111 and 112 continue monitoring.

  On the other hand, when any of the intrusion detection sensors 111 and 112 detects intrusion (Yes in step 1002), a detection signal is output to the system control unit 70. The system control unit 70 drives the mechanism control unit 31 to operate the sample probe 211 when the intrusion detection sensor 111 detects intrusion, and the first reagent probe 221 when the intrusion detection sensor 112 detects intrusion. Stop (step 1003). When the system control unit 70 stops the operation of the sample probe 211 or the first reagent probe 221, the system control unit 70 reads information on the dispensing status from the storage unit 42. The system control unit 70 acquires the number of the reaction cell 232 that needs to be discarded because the operation is stopped before the second reagent is discharged based on the read dispensing status information. When the system control unit 70 acquires information on the reaction cell 232 that needs to be discarded, the system control unit 70 displays the information on the display unit 52 as a warning screen 2000 (step 1004).

  By the way, even when the operation of the sample probe 211 or the first reagent probe 221 is stopped by the operation of Step 1003, the movement of the reaction cell 232 and the dispensing operation of the second reagent probe 224 are continuously performed. If the dispensing operation of the second reagent probe 224 is continuously performed, there may be a situation where the second reagent is dispensed to the reaction cell 232 to be discarded. In order to avoid this situation, when the reaction cell 232 to be dispensed by the second reagent probe 224 is the reaction cell 232 to be discarded, the mechanism control unit 31 stops the operation of the second reagent probe 224. To do. Specifically, when the system control unit 70 displays the warning screen 2000 on the display unit 52 in step 1004, the system control unit 70 acquires the reaction cell 232 to be dispensed with the second reagent probe 224 acquired in step 1004. It is determined whether or not it matches the reaction cell 232 to be discarded (step 1005). When the system control unit 70 determines that the dispensing target of the second reagent probe 224 matches the reaction cell 232 to be discarded (Yes in step 1005), the system control unit 70 drives the mechanism control unit 31 and the second reagent The operation of the probe 224 is stopped (step 1006), and the system control unit 70 waits for an operation of restarting the analysis operation by the operation unit 60 (step 1007). On the other hand, when the system control unit 70 determines that the dispensing target of the second reagent probe 224 is different from the reaction cell 232 to be discarded, that is, the reaction cell 232 that may continue the analysis operation (No in step 1005). The system control unit 70 waits for the analysis operation restart operation by the operation unit 60 (step 1007).

  When the system control unit 70 determines that the operation for resuming the analysis operation has been performed from the operation unit 60 (Yes in step 1008), the system control unit 70 drives the mechanism control unit 31 to stop the sample probe 211, the first The operation of the reagent probe 221 or the second reagent probe 224 is resumed (step 1009), and the process is terminated (step 1010). On the other hand, when the system control unit 70 determines that the operation of resuming the analysis operation from the operation unit 60 has not been performed (No in step 1008), the system control unit 70 returns to step 1005 and continues the processing.

  In the present embodiment, as described in Step 1008, it has been described that the mechanism control unit 31 resumes driving when the user performs the operation of resuming the analysis operation. However, the resumption of driving is not limited to the manual operation by the user, and the system control unit 70 may be configured to automatically resume driving. For example, after the sample probe 211 or the first reagent probe 221 stops operating in step 1003, the mechanism control unit 31 is driven when a certain period of time elapses when the intrusion detection sensors 111 and 112 stop detecting the intrusion. You may control to resume.

  When the intrusion detection sensors 111 and 112 detect the intrusion of the human body by the above processing, the sample probe 211 is detected when the intrusion detection sensor 111 detects the intrusion, and the first reagent probe when the intrusion detection sensor 112 detects the intrusion. The operation of 221 is stopped. Thereby, the needle stick which occurs when a human body contacts the moving probe can be prevented.

  Further, through the above processing, the intrusion detection sensors 111 and 112 detect the intrusion based on the temperature of the object. This allows the analysis operation to continue even when an object that is not subject to needle stick, such as a reagent container or jig for replacement, is placed in the vicinity of the probe. The operation can be stopped if it enters the network. Since the probe is stopped for a human body at risk of needle stick, the probe is not stopped unnecessarily, and as a result, efficient analysis can be performed.

  Further, the second reagent probe 224 continues the dispensing operation even when the operation of the sample probe 211 or the first reagent probe 221 is stopped by the above processing. Thereby, for the reaction cell 232 in which the discharge of the first reagent has been completed, the analysis operation such as the discharge of the second reagent and the component analysis using the light emitting unit and the light receiving unit is continuously performed. Since only the reaction cell 232 that cannot be analyzed due to the stop of the probe is discarded, the number of samples to be discarded and remeasured can be reduced, and as a result, efficient analysis can be performed.

  Further, through the above processing, the second reagent probe 224 stops the dispensing operation when the dispensing target is the reaction cell 232 to be discarded. Thereby, it is possible to discriminate between the reaction cell 232 to be analyzed and the reaction cell 232 to be discarded, and to prevent the second reagent from being discharged into the reaction cell 232 to be discarded.

  Further, when the operation of the sample probe 211 or the first reagent probe 221 is stopped by the above processing, the warning screen 2000 indicates which probe has detected an intrusion and which reaction cell 232 must be discarded. indicate. Thereby, the operator can easily recognize what caused the probe operation to stop and which reaction cell 232 needs to be reanalyzed.

  The present invention is not limited to the above-described embodiments, and can be implemented in various forms without departing from the scope of the invention.

  For example, in this embodiment, the intrusion detection sensors 111 and 112 are provided on the installation shafts of the sample probe 211 and the first reagent probe 221. However, as shown in FIG. 7, a separate mounting shaft for attaching the intrusion detection sensors 111 and 112 may be provided. By providing the sample probe 211 and the first reagent probe 221 and the intrusion detection sensors 111 and 112 separately, the sample probe 211 and the first reagent probe 221 can be configured more simply. In addition, since the attachment positions of the intrusion detection sensors 111 and 112 can be moved regardless of the positions of the installation axes of the sample probe 211 and the first reagent probe 221, the intrusion detection sensors 111 and 112 are moved to positions where intrusion detection can be easily performed. It can be moved.

  Further, for example, as shown in FIG. 8, a lid 3 that covers the upper surface of the automatic analyzer 1 may be provided, and the intrusion detection sensors 111 and 112 may be attached to the lid 3. By providing the lid 3, it is possible to prevent a foreign object or a human body from entering the automatic analyzer 1 while the lid 3 is closed. In addition, while the lid 3 is open, the human body that enters the vicinity of the probe can be detected by the intrusion detection sensors 111 and 112.

  Further, for example, as shown by a dotted line in FIG. 2, the embodiment has been described in which each probe rotates about the installation shaft. However, the moving direction of the probe is not limited to the circumferential direction, and may move in each linear direction, for example.

In addition, various inventions can be formed by appropriately combining a plurality of components disclosed in the embodiment. For example, some components may be deleted from all the components shown in the embodiment. Or you may combine the component covering a different Example suitably.

DESCRIPTION OF SYMBOLS 1 Automatic analyzer 2 Transport rail cover 3 Cover 11 Intrusion detection sensor 21 Sample part 22 Reagent part 23 Reaction part 31 Mechanism control part 41 Calculation part 42 Storage part 51 Printing part 52 Display part 60 Operation part 70 System control part 111 Intrusion detection sensor 112 Intrusion detection sensor 211 Sample probe 212 Sample disk 213 Sample container 214 Sample rack 215 Sample container 216 Transport rail 217 Sample suction notch 221 First reagent probe 222 First reagent disk 223 Reagent container 224 Second reagent probe 225 Second reagent Disk 226 Reagent container 231 Constant temperature bath 232 Reaction cell

Claims (7)

In an automatic analyzer that dispenses samples and reagents into a reaction vessel and measures the mixture,
A sample probe for dispensing the sample into the reaction vessel;
A reagent probe for dispensing the reagent into the reaction vessel;
Probe moving means for moving the sample probe and the reagent probe;
Intrusion detection means for detecting that an object has entered the monitoring area using an infrared detector;
An automatic analyzer comprising: control means for stopping movement of the sample probe or the reagent probe by the probe moving means in response to the intrusion detecting means detecting an intrusion of an object. The automatic analyzer according to claim 1, wherein the intrusion detection unit detects that an object has entered the monitoring area based on the temperature of the object measured using an infrared detector. 3. The automatic analyzer according to claim 1, wherein the intrusion detection unit monitors the monitoring region so as to include a moving range of the sample probe and the reagent probe by the probe moving unit. The control means includes
In response to the intrusion detection unit detecting the intrusion of an object in the vicinity of the sample probe, the movement of the sample probe by the probe moving unit is stopped,
4. The control to stop the movement of the reagent probe by the probe moving means in response to the intrusion detecting means detecting an intrusion of an object in the vicinity of the reagent probe. The automatic analyzer according to item 1. The reagent probe is composed of a first reagent probe for dispensing a first reagent into the reaction container and a second reagent probe for dispensing a second reagent into the reaction container,
The control means includes
In response to the intrusion detection unit detecting the intrusion of an object in the vicinity of the sample probe, the movement of the sample probe by the probe moving unit is stopped,
Stopping the movement of the first reagent probe by the probe moving means in response to the intrusion detecting means detecting the intrusion of an object in the vicinity of the first reagent probe;
4. The automatic analyzer according to claim 1, wherein when the movement is stopped by the probe moving unit, the second reagent probe is controlled to continue dispensing. 5. In an automatic analyzer that dispenses samples and reagents into a reaction vessel and measures the mixture,
A sample probe for dispensing the sample into the reaction vessel;
A first reagent probe for dispensing the first reagent into the reaction vessel;
A second reagent probe for dispensing the second reagent into the reaction vessel;
Probe moving means for moving the sample probe, the first reagent probe, and the second reagent probe;
Intrusion detection means for detecting that an object has entered the monitoring area;
Probe stop means for stopping the movement of the sample probe or the first reagent probe by the probe moving means in response to the intrusion detection means detecting an intrusion of an object;
An automatic analyzer comprising: control means for controlling to continue dispensing of the second reagent probe when movement stop by the probe stop means is performed. In an automatic analyzer that dispenses samples and reagents into a reaction vessel and measures the mixture,
A sample probe for dispensing the sample into the reaction vessel;
A first reagent probe for dispensing the first reagent into the reaction vessel;
A second reagent probe for dispensing the second reagent into the reaction vessel;
Probe moving means for moving the sample probe, the first reagent probe, and the second reagent probe;
A storage unit for storing a dispensing status indicating which of the sample and the first reagent is dispensed in the reaction container based on the dispensing of the sample probe and the first reagent probe;
Intrusion detection means for detecting that an object has entered the monitoring area;
Probe stop means for stopping the movement of the sample probe or the first reagent probe by the probe moving means in response to the intrusion detection means detecting an intrusion of an object;
Read the dispensing status from the storage unit when the movement stop by the probe stop means,
When the second reagent probe dispenses the second reagent to the reaction container in which the sample or the first reagent has not been dispensed based on the read dispensing situation, the second reagent probe An automatic analyzer comprising: control means for controlling to stop dispensing.

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