JP2011137641A - Autoanalyzer - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an autoanalyzer with its analysis accuracy assured at low cost. <P>SOLUTION: This autoanalyzer includes an input part 32 as a setting means for setting the execution of calibration on each of analysis items of a specimen, a set information storage 34a for therein storing set information on the execution of the calibration, an execution determiner 35a for determining whether or not to execute the calibration according to reagent information posted on reagent containers 14a and 16a and read by readers 14b and 16b and to the set information stored in the information storage 34a, and a receiver 35c for receiving an execution command for execution between the calibration and blanking according to the determination result of the execution determiner 35a. <P>COPYRIGHT: (C)2011,JPO&INPIT

Description

  The present invention relates to an automatic analyzer for analyzing a specimen by dispensing a specimen and a reagent into a reaction container and measuring the absorbance of a reaction solution reacted in the reaction container.

  2. Description of the Related Art Conventionally, an automatic analyzer that analyzes a specimen by dispensing a specimen and a reagent into a reaction container and measuring the absorbance of a reaction solution reacted in the reaction container is known. This automatic analyzer performs an actual analysis using a reagent set according to the analysis item for a calibrator that shows a known result for each analysis item of the sample, and based on this analysis result, a standard for measurement processing A calibration process for setting a calibration curve is performed. Thereafter, the automatic analyzer analyzes the reagent subjected to the calibration process using a blank sample such as ion exchange water or physiological saline, and is set in the calibration process based on the analysis result. Analysis accuracy is ensured by performing a blanking process for correcting the calibration curve.

  In addition, an expiration date for accuracy control is set for the results of calibration processing and blank processing, respectively. When either one of the expiration dates has passed, calibration processing and blank processing are automatically set together. And an automatic analyzer that executes calibration processing and blank processing is known (see Patent Document 1).

JP 2008-170191 A

  However, in a specific analysis item performed by the automatic analyzer, for example, an enzyme item, the calibration curve obtained by the calibration process has almost the same result even when the reagent is replenished. For this reason, there is a problem that the cost is increased because the calibration process must be performed even though the blanking process alone can ensure sufficient analysis accuracy.

  The present invention has been made in view of the above, and an object of the present invention is to provide an automatic analyzer that can ensure analysis accuracy at low cost.

  In order to solve the above-described problems and achieve the object, the automatic analyzer of the present invention performs a calibration curve by performing a calibration process for analyzing a calibrator for each analysis item of a sample and a blank process for analyzing a blank sample. In the automatic analyzer for analyzing the sample by converting the absorbance of the reaction solution obtained by reacting the sample and the reagent in the reaction container using the calibration curve into a measured value, for each analysis item of the sample A setting means for setting the execution of the calibration process, a setting information storage means for storing setting information related to the execution of the calibration process set by the setting means, and a reagent container containing the reagent, Reading means for reading the reagent information from a storage medium storing reagent information including the analysis item, bottle number, and lot number of the reagent; In accordance with the reagent information read by the means and the setting information stored in the setting information storage means, an execution determination means for determining whether or not to execute the calibration process, and a determination result of the execution determination means And a receiving unit that receives an execution command of a process to be executed from among the calibration process and the blanking process, and the receiving unit determines that the execution determination unit does not execute the calibration process The reception of the execution command for the calibration process is stopped.

  Moreover, in the above-described invention, the automatic analyzer according to the present invention is the blank information storage unit that stores the reagent information of the reagent used in the blank process that has been performed, and the blank information storage unit that has been executed. Reagent information determination means for determining whether or not the reagent information of the reagent used in the blanking process matches the reagent information read by the reading means, and the receiving means includes the reagent information When the determination result by the determination means is inconsistent, an execution command for the blank process is received.

  The automatic analyzer according to the present invention further includes a calibration information storage unit that stores the reagent information of the reagent used in the calibration process that has been performed in the above-described invention, and the reagent information determination unit includes: Determining whether or not the reagent information of the reagent used for the executed calibration process stored in the calibration information storage unit matches the reagent information read by the reading unit; When the determination result by the reagent information determination means is inconsistent, an execution command for the calibration process is received.

  Moreover, the automatic analyzer according to the present invention is characterized in that, in the above-mentioned invention, the execution command for the quality control process for analyzing the quality control sample is received together with the execution command for the blank process.

  The automatic analyzer according to the present invention performs calibration according to the reagent information read from the storage medium attached to the reagent container containing the reagent and the setting information related to the execution of the calibration process set for each analysis item of the sample. If it is determined whether or not to execute the calibration process, and it is determined that the calibration process is not to be executed, the calibration process is stopped only for the analysis item of the required sample by stopping acceptance of the calibration process execution command. Since the execution is accepted, the analysis accuracy can be ensured at a low cost.

FIG. 1 is a schematic diagram showing a schematic configuration of an automatic analyzer according to an embodiment of the present invention. FIG. 2 is a diagram showing a reagent information table showing reagent information of reagents stored in the first reagent store and the second reagent store. FIG. 3 is a diagram showing a selection screen for setting execution of blank processing and quality control processing for the reagents stored in the first reagent storage and the second reagent storage. FIG. 4 is a diagram showing a calibration processing analysis item selection screen for setting execution of calibration processing for each analysis item of the sample. FIG. 5 is a flowchart showing the reception process by the reception processing unit of the automatic analyzer. FIG. 6 is a diagram showing a selection screen for setting execution of blank processing and quality control processing for the reagents stored in the first reagent storage and the second reagent storage.

  DESCRIPTION OF EMBODIMENTS Hereinafter, preferred embodiments of an automatic analyzer according to the present invention will be described in detail with reference to the drawings. The invention is not limited to the embodiments. In the description of the drawings, the same parts are denoted by the same reference numerals.

  FIG. 1 is a schematic diagram showing a schematic configuration of an automatic analyzer according to an embodiment of the present invention. As shown in FIG. 1, an automatic analyzer 1 according to an embodiment of the present invention reacts a reagent with a sample and measures the absorbance of the reaction solution, and an automatic including the measurement mechanism 2. And a control mechanism 3 that controls the entire analysis apparatus 1 and analyzes the measurement result in the measurement mechanism 2. The automatic analyzer 1 automatically analyzes a plurality of specimens by the cooperation of these two mechanisms.

  First, the measurement mechanism 2 will be described. As shown in FIG. 1, the measurement mechanism 2 includes a sample transport unit 11 that sequentially transports a sample rack 11b holding a plurality of sample containers 11a containing a sample such as blood or urine, in the direction of the arrow in the figure. , A sample dispensing mechanism 12 for dispensing a sample from the sample container 11a stopped at the sample aspiration position P1 on the sample transfer unit 11 to the reaction container, and a reagent containing the first reagent dispensed in the reaction container 13 A first reagent dispenser that dispenses a first reagent into a reaction container 13 from a reagent container 14a to be dispensed stopped at a reagent suction position P2 of the first reagent container 14 and a first reagent container 14 that accommodates a plurality of containers 14a. The mechanism 15, the second reagent storage 16 storing a plurality of reagent containers 16a storing the second reagent to be dispensed in the reaction container 13, and the dispensing symmetry stopped at the reagent suction position P3 of the second reagent storage 16. From the reagent container 16a to the reaction container 13 A second reagent dispensing mechanism 17 for dispensing the medicine, a stirring unit 18 for stirring the liquid dispensed in the reaction vessel 13, a photometric unit 19 for measuring the absorbance of the liquid dispensed in the reaction vessel 13, A cleaning unit 20 for cleaning the reaction vessel 13 for which the measurement by the photometric unit 19 has been completed, and the reaction vessel 13 is transported to a predetermined position in order to perform dispensing, stirring, photometry, and washing of the sample and reagent in the reaction vessel 13 Reaction vessel 21.

  In addition, a storage medium (not shown) in which reagent information for identifying a reagent contained therein is stored is affixed to each of the reagent container 14a and the reagent container 16a. The storage medium is realized by a bar code or a two-dimensional code, and stores reagent information related to the reagent. In addition, a reading unit 14b and a reading unit 16b for optically reading the storage medium are provided on the outer periphery of the first reagent store 14 and the second reagent store 16, respectively. The reading units 14b and 16b are realized by a barcode reader or the like, and emit reagents such as infrared light or visible light to the storage medium, and process the reflected light from the storage medium, whereby the reagent relating to the reagent stored in the storage medium Read information. The reading units 14 b and 16 b output the read reagent information to the control mechanism 3. Here, the reagent information means at least a reagent analysis item, a bottle number, a lot number, a type, a liquid amount, a bottle shape, an expiration date, an expiration date after opening, and the like.

  Next, the control mechanism 3 will be described. The control mechanism 3 is realized by a CPU or the like, and is realized by a control unit 31 that controls processing and operation of each unit of the automatic analyzer 1, a keyboard, a mouse, a touch panel having an input / output function, and the like, and is necessary for analysis of a sample. By an input unit 32 to which detailed information and operation information of the automatic analyzer 1 are input, an analysis unit 33 that performs component analysis of the sample based on the measurement result of the absorbance measured by the photometry unit 19, and a hard disk, a memory, and the like A storage unit 34 that stores various types of information including information related to various programs and sample analysis that are realized and related to the processing and operation of each unit of the automatic analyzer 1, and performs calibration processing and blank processing for each analysis item of the sample. This is realized by a reception processing unit 35 that accepts the execution of a sample and a display, a printer, etc., and outputs information related to analysis of the sample And an output unit 36.

  In addition, the input unit 32 sets execution of a calibration process for analyzing a calibrator for each analysis item of a specimen, and also executes a blank process for analyzing a blank sample for each reagent information of a reagent and / or analyzes a quality control sample. It functions as a setting means for setting the execution of quality control processing.

  The storage unit 34 includes a setting information storage unit 34a, a reagent information storage unit 34b, a calibration information storage unit 34c, and a blank information storage unit 34d. The setting information storage unit 34a stores setting information regarding execution of the blanking process and / or execution of the quality control process together with setting information regarding execution of the calibration process input by the operator to the input unit 32. The reagent information storage unit 34b stores the reagent information read by the reading units 14b and 16b from the storage medium attached to the reagent containers 14a and 16a. The calibration information storage unit 34c stores reagent information and analysis results of reagents used in the already executed calibration process. The reagent information storage unit 34b stores reagent information and analysis results of the reagents used in the executed blank process. Here, the reagent information and analysis results of the reagents used in the already executed calibration process are the analysis process when the sample analysis process is stopped while the automatic analyzer 1 is powered on. This refers to the latest reagent information and analysis results of the reagents used for the execution of the calibration process during the accompanying pre-processing or post-processing. In addition, the reagent information and analysis results of the reagents used for the blank process that has been executed are the information before the analysis process when the sample analysis process is stopped while the power is turned on to the automatic analyzer 1. This refers to the latest reagent information and analysis result of the reagent used for the execution of the blank process at the time of processing or post-processing.

  The reception processing unit 35 includes an execution determination unit 35a, a reagent information determination unit 35b, and a reception unit 35c. The execution determination unit 35a executes calibration processing according to the reagent information read by the reading units 14b and 16b from the storage medium attached to the reagent containers 14a and 16a and the setting information stored in the setting information storage unit 34a. It is determined whether or not. The reagent information determination unit 35b determines whether or not the reagent information read by the reading units 14b and 16b matches the reagent information of the reagent used for the executed blank process stored in the blank information storage unit 34d. The reagent information determination unit 35b determines whether or not the reagent information read by the reading units 14b and 16b and the reagent information of the reagent used for the executed calibration process stored in the calibration information storage unit 34c match. To do. The accepting unit 35c accepts an execution command for a process to be executed from among the calibration process and the blank process according to the determination result of the execution determining part 35a. If the execution determination unit 35c determines not to execute the calibration process, the reception unit 35c stops receiving the calibration process execution command. In addition, when the reagent information determination unit determines that the reagent information read by the reading units 14b and 16b does not match the reagent information of the reagent used in the executed blank process, the reception unit 35c issues a blank process execution command. To accept. Furthermore, when the reagent information determination unit determines that the reagent information read by the reading units 14b and 16b does not match the reagent information of the reagent used for the already executed calibration process, the reception unit 35c executes the calibration process. Accept orders.

  In the automatic analyzer 1 configured as described above, the first reagent dispensing mechanism 15 is located at the reagent suction position P2 of the first reagent storage 14 with respect to the plurality of reaction containers 13 that are sequentially transferred on the reaction tank 21. After dispensing the first reagent from the stopped reagent container 14a to be dispensed, the sample dispensing mechanism 12 dispenses the sample from the sample container 11a stopped at the sample aspiration position P1, and the second reagent dispensing mechanism 17 The second reagent is dispensed from the reagent container 16a to be dispensed stopped at the reagent suction position P3 of the two reagent storage 16. Thereafter, the photometry unit 19 measures the absorbance of the reaction solution in the state in which the first reagent, the sample, and the second reagent are reacted, and the analysis unit 33 analyzes based on the measurement result, so that the component analysis of the sample can be performed. Done automatically. Thereafter, the cleaning unit 20 performs cleaning while transporting the reaction vessel 13 transported after the measurement by the photometry unit 19 is completed. Thereafter, the washed reaction vessel 13 is reused.

  Here, with reference to FIG. 2, the reagent which the 1st reagent storage 14 and the 2nd reagent storage 16 accommodate is demonstrated. FIG. 2 is a diagram illustrating an example of a reagent information table indicating reagent information of reagents stored in the first reagent store and the second reagent store.

  The reagent information table R1 shown in FIG. 2 describes the reagent information of the reagents stored in the first reagent container 14 and the second reagent container 16. In the first reagent storage 14, for example, information that the analysis item is “ALT”, the lot number is “1000”, and the bottle number is “0001” is described. On the other hand, in the second reagent storage 16, for example, information that the analysis item is “ALT”, the lot number is “3000”, and the bottle number is “1001” is described.

  Next, with reference to FIG. 3, the setting of the blank process and the quality control process will be described based on the reagent information related to the reagents stored in the first reagent container 14 and the second reagent container 16. FIG. 3 is a diagram showing a display example on the display of the output unit of the selection screen for setting execution of the blank process and the quality control process for the reagents stored in the first reagent store and the second reagent store.

  In the selection screen W1 shown in FIG. 3, a setting table R2 for setting execution of blank processing and quality control processing for the reagents stored in the first reagent storage 14 and the second reagent storage 16 is displayed. The operator moves the cursor Y1 from the check box corresponding to the reagent bottle number set according to the analysis item using the mouse of the input unit 32 to the desired check box, and selects it by clicking the mouse. To do. As a result, the check symbol “” is displayed in the check box. Thereafter, the operator moves the cursor Y1 to the OK button B1 and clicks the mouse to determine the setting for executing the blank process and the quality control process. Thus, in FIG. 3, for example, the lot number of the first reagent is “1000” and the bottle number is “0001”, the lot number of the second reagent is “3000”, and the bottle number is “1001”. In the analysis item “ALT”, execution of blank processing and quality control processing is set in the check boxes CG11 and CG21. In addition, in the analysis item “AST” in which the lot number of the first reagent is “2000” and the bottle number is “0001”, the lot number of the second reagent is “4000” and the bottle number is “1001”, check boxes Execution of blank processing is set in CG14. On the other hand, in the analysis item “AST” in which the lot number “2000” and the bottle number of the first reagent are “0001” and the lot number “4000” and the bottle number of the second reagent are “1001”, the accuracy management process is performed. Execution is not set. Setting information relating to the execution of blank processing and quality control processing corresponding to the contents set in the setting table R2 is output from the input unit 32 via the control unit 31 to the setting information storage unit 34a and stored therein.

  In the automatic analyzer 1 according to the embodiment of the present invention, the execution of the calibration process and the execution of the blank process are set separately for each analysis item of the sample. When a calibration curve is set by performing calibration processing, it is desirable to perform blank processing together with correction of the set calibration curve.

  With reference to FIG. 4, the setting of the calibration process to be executed for each analysis item of the sample will be described. FIG. 4 is a diagram showing a display example on the display of the output unit of the analysis item selection screen for calibration processing for selecting the analysis item for executing the calibration processing for each analysis item of the sample.

  The calibration process analysis item selection screen W2 shown in FIG. 4 displays a calibration process analysis item selection table R3 for setting the execution of the calibration process for each analysis item of the sample. The operator uses the mouse of the input unit 32 or the like to move the cursor Y1 from a check box corresponding to the analysis item of the sample to a desired check box, and selects it by clicking the mouse. As a result, the check symbol “” is displayed in the check box. Thereafter, the operator moves the cursor Y1 to the OK button B2 and clicks the mouse to confirm the setting for executing the calibration process. In this way, in FIG. 4, for example, in the analysis item “ALT”, execution of the calibration process is set in the check box CG31. Setting information relating to the execution of calibration processing corresponding to the content set in the calibration processing analysis item selection table R3 is output from the input unit 32 via the control unit 31 to the setting information storage unit 34a and stored therein.

  Next, reception processing by the reception processing unit 35 of the automatic analyzer 1 will be described with reference to the flowchart shown in FIG. In the following, a series of processes when a reagent set according to an analysis item is stored in the first reagent storage 14 will be described.

  First, the reception processing unit 35 determines whether there is a newly received reagent via the control unit 31 (step S101). Specifically, when the analysis process is stopped while the automatic analyzer 1 is powered on, the reading unit 14b reads from the storage medium affixed to the reagent container 14a during pre-processing or post-processing. It is determined whether the reagent information stored in the reagent information storage unit 34b or whether there is a newly received reagent based on the information input to the input unit 32 by the operator. When it is determined that there is no newly received reagent (step S101: No), the determination process of step S101 is repeated. On the other hand, when it is determined that there is a newly received reagent (step S101: Yes), the reception processing unit 35 acquires the reagent information of the newly received reagent from the reagent information storage unit 34b via the control unit 31. (Step S102).

  Thereafter, the reception processing unit 35 acquires setting information stored in the setting information storage unit 34a via the control unit 31 (step S103). Specifically, the setting information related to the execution of the calibration process set in the calibration process analysis item selection table R3 shown in FIG. 4 is acquired.

  Thereafter, the execution determination unit 35a determines whether or not to execute the calibration process on the received reagent according to the reagent information and the setting information acquired by the reception processing unit 35 (step S104). Specifically, it is determined whether or not the analysis item of the reagent information matches the analysis item of the setting information. When it is determined that the calibration process is not performed on the received reagent (step S104: No), the process proceeds to step S105. On the other hand, when it determines with performing a calibration process with respect to the received reagent (step S104: Yes), it transfers to step S107.

  In step S105, the reagent information determination unit 35b determines whether the received reagent information of the reagent matches the reagent information of the reagent used in the executed blank process stored in the blank information storage unit 34d. Specifically, the reagent information determination unit 35b determines whether or not the bottle number in the reagent information of the received reagent matches the bottle number in the reagent information of the reagent used for the executed blank process. When it is determined that the reagent information of the received reagent does not match the reagent information of the reagent used for the executed blank process (step S105: No), the receiving unit 35c performs blank processing and accuracy control on the received reagent. A process execution command is received (step S106), and the process ends. On the other hand, when it is determined that the reagent information of the received reagent matches the reagent information of the reagent used for the executed blank process (step S105: Yes), this process ends.

  In step S107, the reagent information determination unit 35b determines whether or not the received reagent information of the reagent matches the reagent information of the reagent used in the executed calibration process stored in the calibration information storage unit 34c. To do. Specifically, the reagent information determination unit 35b determines whether or not the analysis item in the received reagent information of the reagent matches the analysis item in the reagent information of the reagent used in the already executed calibration process. When it is determined that the reagent information of the received reagent and the reagent information of the reagent used for the already executed calibration process do not match (step S107: No), the process proceeds to step S108. On the other hand, if it is determined that the reagent information of the received reagent matches the reagent information of the reagent used in the already executed calibration process (step S107: Yes), the process proceeds to step S111.

  In step S108, the reagent information determination unit 35b determines whether or not the received reagent information of the reagent matches the reagent information of the reagent used in the executed blank process stored in the blank information storage unit 34d. If it is determined that the reagent information of the received reagent does not match the reagent information of the reagent used for the executed blank process (step S108: No), the receiving unit 35c performs a calibration process and a blank for the received reagent. An execution command for the process and the quality control process is received (step S109), and this process ends. On the other hand, when it is determined that the reagent information of the received reagent matches the reagent information of the reagent used for the executed blank process (step S108: Yes), the receiving unit 35c performs a calibration process on the received reagent. Is received (step S110), and the process ends.

  In step S111, the reagent information determination unit 35b determines whether or not the received reagent information of the reagent matches the reagent information of the reagent used in the executed blank process stored in the blank information storage unit 34d. When it is determined that the reagent information of the received reagent does not match the reagent information of the reagent used for the executed blank process (step S111: No), the receiving unit 35c performs blank processing and accuracy control for the received reagent. A process execution command is received (step S112), and the process ends. On the other hand, when it is determined that the reagent information of the received reagent matches the reagent information of the reagent used for the executed blank process (step S111: Yes), this process ends.

  In one embodiment of the present invention, the execution determination unit 35a uses the reagent information read by the reading units 14b and 16b from the storage medium attached to the reagent containers 14a and 16a and the setting information stored in the setting information storage unit 34a. Accordingly, it is determined whether or not to execute the calibration process, and when the execution determination unit 35a determines not to execute the calibration process, the reception unit 35c stops receiving the calibration process execution command. Therefore, the execution of the calibration process is accepted only in the case of a necessary sample analysis item. That is, since the calibration process and the blank process are set separately, it is not necessary to perform the calibration process and the blank process as a set. As a result, the cost burden due to the calibration process can be reduced and the analysis accuracy can be ensured.

  In one embodiment of the present invention, the reagent information determination unit 35b is affixed to the reagent containers 14a and 16a read by the reading unit 14b and 16b and the reagent information of the reagent used in the already executed calibration process. By determining whether or not the reagent information stored in the storage medium matches, the analysis result by the executed calibration process and the analysis result by the executed blank process can be used. In addition to reducing the cost burden due to the reagent, it is possible to prevent the reagent from being wasted due to the blanking process. Furthermore, by using the analysis results of the already executed calibration process and blank process, the time spent for the calibration process and the blank process can be prevented, and the efficiency of the analysis process of the entire automatic analyzer 1 can be improved. Can do.

  Further, in one embodiment of the present invention, the execution of blank processing and accuracy control is set for each bottle number of reagent information, but for example, for each lot number of reagent information, as shown in FIG. You may make it set execution of a blank process and a quality control process. In this case, when there are a plurality of the same lot numbers in the analysis item, only one lot number is displayed, and execution of blank processing and quality control processing is set for the setting table R4 shown in FIG. Also good. Thereby, time spent for the calibration process and the blank process can be prevented, and the efficiency of the analysis process of the entire automatic analyzer 1 can be improved.

  Further, in the embodiment of the present invention, the check symbol “re” is displayed as the setting information for selecting execution of the calibration process, the blank process, and the quality control process on the selection screens W1 to W3. For example, the selected item may be displayed with a color, a line, or the like.

  In the embodiment of the present invention, when the execution of the blank process is received, the execution of the quality control process is also received. However, the present invention is not limited to this, and the analysis item of the sample, the bottle number of the reagent, and the lot You may make it receive the execution instruction | indication of a quality control process for every number.

  In one embodiment of the present invention, an expiration date for accuracy control is provided for reagent information and analysis results of reagents used in the calibration processing and blank processing that have been executed, and this expiration date has passed. In this case, an execution command for calibration processing or blank processing may be received. Thereby, higher analysis accuracy can be ensured.

  In the embodiment of the present invention, the execution of the calibration process is set for each analysis item of the sample via the calibration process analysis item selection screen W2. However, the present invention is not limited to this. Execution of calibration processing may be set for each analysis item. In this case, setting information related to the execution of the calibration process may be stored in the storage unit 34.

DESCRIPTION OF SYMBOLS 1 Automatic analyzer 2 Measuring mechanism 3 Control mechanism 11 Specimen transfer part 11a Specimen container 11b Specimen rack 12 Specimen dispensing mechanism 13 Reaction container 14 1st reagent storage 14a, 16a Reagent container 14b, 16b Reading part 15 1st reagent dispensing mechanism 16 Second reagent storage 17 Second reagent dispensing mechanism 18 Stirring unit 19 Photometry unit 20 Washing unit 21 Reaction tank 31 Control unit 32 Input unit 33 Analysis unit 34 Storage unit 34a Setting information storage unit 34b Reagent information storage unit 34c Calibration information Storage unit 34d Blank information storage unit 35 Reception processing unit 35a Execution determination unit 35b Reagent information determination unit 35c Reception unit 36 Output unit R1 Reagent information table R2, R4 setting table R3 Analysis item selection table for calibration processing W1, W3 selection screen W2 Analysis item selection screen for calibration processing

Claims (4)

A calibration curve is set by performing a calibration process for analyzing the calibrator for each analysis item of the sample and a blank process for analyzing the blank sample, and the sample and the reagent are reacted in the reaction container using the calibration curve. In an automatic analyzer that analyzes the sample by converting the absorbance of the reaction solution into a measured value,
Setting means for setting execution of the calibration process for each analysis item of the sample;
Setting information storage means for storing setting information related to execution of the calibration process set by the setting means;
Reading means for reading the reagent information from a storage medium affixed to the reagent container containing the reagent and storing reagent information including the analysis item, bottle number, and lot number of the reagent;
Execution determination means for determining whether to execute the calibration process according to the reagent information read by the reading means and the setting information stored by the setting information storage means;
According to the determination result of the execution determination unit, a reception unit that receives an execution command of a process to be executed from among the calibration process and the blank process;
The automatic analysis apparatus is characterized in that, when the execution determination unit determines not to execute the calibration process, the reception unit stops receiving the calibration process execution command. A blank information storage unit for storing the reagent information of the reagent used in the executed blank process;
Reagent information determination means for determining whether or not the reagent information of the reagent used for the executed blank process stored in the blank information storage unit matches the reagent information read by the reading means;
2. The automatic analyzer according to claim 1, wherein when the determination result by the reagent information determination unit is inconsistent, the reception unit receives an execution command for the blank process. A calibration information storage unit for storing the reagent information of the reagent used in the calibration process that has been executed;
The reagent information determination means determines whether or not the reagent information of the reagent used in the executed calibration process stored in the calibration information storage unit matches the reagent information read by the reading means. Judgment,
3. The automatic analyzer according to claim 1, wherein the reception unit receives an instruction to execute the calibration process when the determination result by the reagent information determination unit does not match. 4.   The automatic analyzer according to any one of claims 1 to 3, wherein the accepting unit accepts an execution command for a quality control process for analyzing a quality control sample together with the execution command for the blank process.

Images