JP2011132184A - Disinfectant composition for hand and finger - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a gel-like disinfectant composition for hand and fingers preventing stickiness, a residual feeling after use, and formation of creases, and having low-temperature stability. <P>SOLUTION: The disinfectant composition for hand and fingers includes: 40-90 wt.% of a lower alcohol; 0.02-0.1 wt.% of an acrylic acid-alkyl methacrylate copolymer; and 0.01-0.1 wt.% of diisopropanolamine. <P>COPYRIGHT: (C)2011,JPO&INPIT

Description

  The present invention relates to a hand sanitizer composition that suppresses the use of a thickener and is excellent in salt resistance and low-temperature stability.

As a means for easily disinfecting fingers, a gel-like disinfectant is used. A gel-like disinfectant is usually added with a thickener for the purpose of obtaining a predetermined “elongation” during use in order to prevent dripping.
As the thickener, carboxyvinyl polymer is widely used. Further, cellulose polymers and those using acrylic acid / alkyl methacrylate copolymers have also been proposed (Patent Documents 1 to 5).
However, when the amount of the thickener added to obtain the necessary viscosity increases, there are problems such as stickiness, a feeling of persistence after use, and a twist. Further, when an acrylic acid / alkyl methacrylate copolymer is used as a thickener, it has been necessary to add cyclic silicon to remove stickiness or residual feeling during use.
In addition, hand sanitizers are often used in the relatively cold season to prevent various infectious diseases, and may be stored and used not only indoors but also outdoors. There is also a problem that a part of the thickener is precipitated at a low temperature in the winter, the inside of the system becomes cloudy and the viscosity is lowered.

JP-A-4-305504 JP-A-5-255078 JP-A-8-92078 JP-A-6-199700 JP 2006-83119 A

  An object of the present invention is to provide a gel-like hand disinfectant that prevents stickiness, a feeling of persistence after use, and generation of warping, and has low-temperature stability.

As a result of studying the types and amounts of the thickener and the neutralizing agent, the inventors of the present application have found that the above-described problems can be solved by making them predetermined, and have completed the present invention.
That is, the present invention contains 40 to 90% by weight of a lower alcohol, 0.02 to 0.1% by weight of an acrylic acid / alkyl methacrylate copolymer, and 0.01 to 0.1% by weight of diisopropanolamine. A hand sanitizer composition is provided.

According to the present invention, it is possible to obtain a gel-like disinfectant for a finger that suppresses the use of a thickener, does not sag from the hand during use, does not distort, and has no stickiness or residual feeling after use.
Furthermore, the hand disinfectant having the above composition is stable even at low temperatures and can be used stably for a long time without precipitation of the thickener. For example, the hand sanitizer composition of the present invention can be used in a stable gel state even when stored at 0 ° C. or lower.

  The hand sanitizer composition of the present invention comprises 40 to 90% by weight of a lower alcohol, 0.02 to 0.1% by weight of an acrylic acid / alkyl methacrylate copolymer, and 0.01 to 0.1 of diisopropanolamine. Contains% by weight.

  The lower alcohol used in the hand sanitizer composition of the present invention is not particularly limited, and examples thereof include alcohols having 1 to 5 carbon atoms such as ethanol and isopropanol. In the present invention, ethanol is most preferred.

  The amount of the lower alcohol contained in the hand sanitizer composition of the present invention is 40 to 90% by weight, preferably 65 to 75% by weight.

  The acrylic acid / alkyl methacrylate copolymer used in the disinfectant composition for fingers of the present invention is not particularly limited as long as it is used for various skin cosmetics and drugs. For example, a copolymer of at least one monomer composed of acrylic acid, methacrylic acid or a simple ester thereof and an alkyl acrylate (such as one having 10 to 30 carbon atoms) is mixed with an allyl ester of sucrose or an allyl ether of pentaerythritol. Cross-linked products can be used. For example, commercially available products such as Carbopol 1342, Carbopol 1382, and Carbopol ETD2020 (manufactured by Nikko Chemical Co., Ltd.) can be used. Of these, Carbopol ETD2020 is particularly preferable.

  The hand sanitizer composition of the present invention contains acrylic acid / alkyl methacrylate copolymer in an amount of 0.02 to 0.1% by weight, preferably 0.05 to 0.1% by weight, based on the whole composition. .

Moreover, the disinfectant composition for fingers of the present invention contains 0.01 to 0.1% by weight, preferably 0.03 to 0.06% by weight of diisopropanolamine. Furthermore, the content of the diisopropanolamine is preferably 10% to 300%, more preferably 20% to 100% with respect to the content of the acrylic acid / alkyl methacrylate copolymer.
By including diisopropanolamine within the above range, the acrylic acid / alkyl methacrylate copolymer contained in the hand disinfectant composition of the present invention exhibits a preferable effect as a thickener.

Generally, when a thickener such as carboxyvinyl polymer or acrylic acid / alkyl methacrylate copolymer is used, a basic substance is simultaneously added to form a gel. Here, acrylic acid / alkyl methacrylate copolymer is used as a thickener, and by using this and diisopropanolamine in combination with the above content, the amount of thickener used is 0.1% by weight. Even in the following cases, it is possible to maintain a predetermined gel-like form. As a result, the amount of thickener used in the hand sanitizer composition can be suppressed, and an effect of preventing stickiness and a feeling of remaining after use can be obtained. Therefore, it is not necessary to add cyclic silicon or the like in order to obtain the predetermined stickiness / residual feeling prevention effect necessary as a gel-like disinfectant composition.
Furthermore, the hand disinfectant of the present invention having the above composition has excellent salt resistance, and is not easily affected by salt such as sweat when rubbed into the hand, so there is no occurrence of twist and a thickener at low temperature. Is also suppressed, and is excellent in low-temperature stability.

The hand sanitizer composition of the present invention may further contain a bactericidal agent and / or a moisturizing agent, if necessary.
The bactericidal agent can be appropriately selected by those skilled in the art. Triclosan can be used. Among the above, it is preferable to use benzalkonium chloride in the present invention. When using a bactericidal agent, the usage-amount can be 0.01-1.0 weight%, for example, and it is more preferable to set it as 0.05-0.2 weight%.

  Similarly, the humectant can be appropriately selected by those skilled in the art. For example, glycerin, propylene glycol, dipropylene glycol, urea, hyaluronic acid, sodium hyaluronate, lactic acid, and sodium lactate can be used. Among the above, glycerin is preferably used in the present invention. When using a humectant, the content can be, for example, 0.01 to 2.0% by weight, and more preferably 0.05 to 1.0% by weight.

The total amount of the hand disinfectant of the present invention can be adjusted using purified water as a solvent other than the lower alcohol.
EXAMPLES Hereinafter, although this invention is further demonstrated with reference to an Example, this invention is not limited to these.

  Examples and Comparative Examples were prepared in the usual manner according to the composition shown in Table 1, and each composition was evaluated. The evaluation criteria are as follows.

Amount of salt to the formulation upon addition of corrosion salt of 1% saline solution is cloudy (NaCl concentration: ppm)
Low temperature stability Appearance (one month) of liquid when each sample is placed in a hand sanitizer container and stored at 0C.
○: Transparent △: Some turbidity is seen ×: Liquid is cloudy
Sagging ○: No sagging △: Slight sagging ×: Sagging

Stickiness ○: No stickiness △: Slightly sticky ×: Stickiness
Twist ○: No twist △: Twist occurs slightly ×: Twist occurs
Residual feeling ○: No residual feeling Δ: Slight residual feeling ×: Residual feeling

The evaluation results are as shown in Table 1 below. In addition, evaluation of Table 1 is made to use 10 trial users, and the result was put together by the average value.

  From the results of Table 1, it can be seen that the hand sanitizer composition of the present invention has improved salt resistance and low-temperature stability. In addition, there is no dripping or twisting from the hand during use, and good results are also obtained in stickiness and remaining feeling.

Claims (2)

  Disinfectant composition for fingers comprising 40 to 90% by weight of lower alcohol, 0.02 to 0.1% by weight of acrylic acid / alkyl methacrylate copolymer and 0.01 to 0.1% by weight of diisopropanolamine object.   The disinfectant composition for fingers according to claim 1, further comprising a disinfectant and / or a humectant.