JP2011062320A - Guide wire and catheter system - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a guide wire capable of excellently guiding a catheter. <P>SOLUTION: In the guide wire 1000, an operation cable 1200 freely slidably inserted to the hollow inside of a freely bendable hollow wire body 1100 is eccentrically connected at a distal end, the proximal end part of the operation cable 1200 is slid and moved by a bending operation mechanism 1300 and at least the distal end part 1110 of the wire body 1100 is bent. The guide wire 1000 is inserted to a tubular catheter 2000 and utilized as the catheter system 100. In the catheter system 100, the distal end part 1110 of the guide wire 1000 is freely bent by the manual operation of the bending operation mechanism 1300 at the proximal end part. <P>COPYRIGHT: (C)2011,JPO&INPIT

Description

  The present invention relates to a guide wire used for guiding a catheter into a blood vessel, and a catheter system including the guide wire and the catheter.

  In recent years, various catheter systems have been used in the medical field. For example, there is a catheter system that guides a catheter to a desired site of a complex branching blood vessel using a guide wire having a bent distal end.

Japanese Patent Laid-Open No. 2004-180891 Japanese Patent Laid-Open No. 06-218060

  The catheter system as described above utilizes a guide wire to bend the distal end of the catheter and guide it to the desired site of the branching blood vessel. However, in such a catheter system, the guiding of the catheter depends on the bent shape of the distal end portion of the guide wire, and the degree of freedom thereof is low.

  For example, when a catheter is guided to a blood vessel branched at an acute angle, the catheter is guided by inserting a guide wire therethrough. However, when the consistency between the bent shape of the distal end portion of the guide wire and the branch shape of the blood vessel is not good, it may be difficult to guide the catheter.

  The present invention has been made in view of the above problems, and provides a guide wire capable of guiding a catheter with a good degree of freedom, and a catheter system including the guide wire and the catheter.

  The guide wire of the present invention is a guide wire for guiding a catheter, and is bent and hollow, and is slidably inserted into the hollow inside of the wire body and eccentrically connected at the distal ends of each other. And a bending operation mechanism that slides the proximal end of the operation cable to bend the distal end of the wire body.

  Therefore, in the guide wire of the present invention, the operation cable slidably inserted into the hollow inside of the bendable wire body is eccentrically connected at the distal end, and the proximal end portion of the operation cable is bent. At least the distal end of the wire body is bent by being slid by the operation mechanism. This guide wire is inserted into a tubular catheter and used as a catheter system. In this catheter system, the distal end portion of the guide wire is freely bent by the operation of the bending operation mechanism at the proximal end portion.

  Further, in the guide wire as described above, the wire body may be formed so that the bending rate is uneven in the direction from the distal end to the proximal end of the distal end portion.

  In the guide wire as described above, the wire main body is divided into a plurality of bendable bendable portions in the direction from the distal end to the proximal end, and the bending ratio of the plurality of bendable portions is It may be different.

  In the guide wire as described above, the wire body may be formed of a winding coil, and the winding pitch of the plurality of bendable portions may be different.

  Further, in the guide wire as described above, the wire body may have at least three bendable portions with a winding pitch dense, coarse, and dense in the direction from distal to proximal.

  The guide wire as described above may further include a core material that is inserted into the hollow interior of the wire main body and is sharper toward the distal end within the bendable portion.

  Further, in the guide wire as described above, an operation cable may be slidably inserted in a concave groove formed in the outer peripheral surface of the core material.

  Further, in the guide wire as described above, a resin layer is formed on the outer peripheral surface of the core material, and an operation cable is slidably inserted into at least one of a concave groove or a through hole formed in the resin layer. May be.

  The catheter system of the present invention includes the guide wire of the present invention and a tube-shaped catheter through which the guide wire is inserted.

  Note that the various components of the present invention do not have to be individually independent, that a plurality of components are formed as one member, and one component is formed of a plurality of members. It may be that a certain component is a part of another component, a part of a certain component overlaps a part of another component, and the like.

  Further, the difference in the bending ratio in the present invention means that the curvature of the arc-shaped bend is different, the shape of the arc-shaped bend is different, or at least one of these combinations. is doing.

  The guide wire of the present invention is inserted into a tubular catheter and used as a catheter system. In this catheter system, the distal end portion of the guide wire is freely bent by the operation of the bending operation mechanism at the proximal end portion. Therefore, the operability for guiding the catheter to the blood vessel having a complicated structure is good.

It is a side view showing the whole catheter system of an embodiment of the invention. It is a side view which shows the whole guide wire. It is a vertical side view which shows the internal structure of a guide wire. It is a vertical front view which shows the internal structure of a guide wire. It is a mimetic diagram showing the state where a plurality of bendable parts bend by operation of a bending operation mechanism. It is a vertical front view which shows the internal structure of the guide wire of one modification. It is a vertical side view which shows the internal structure of the guide wire of another modification. It is a mimetic diagram showing the state where a plurality of bendable parts bend by operation of a bending operation mechanism. It is a vertical side view which shows the internal structure of the guide wire of another modification. It is a mimetic diagram showing the state where a plurality of bendable parts bend by operation of a bending operation mechanism. It is a vertical front view which shows the internal structure of a guide wire. It is a vertical side view which shows the internal structure of the guide wire of another modification. It is a mimetic diagram showing the state where a plurality of bendable parts bend by operation of a bending operation mechanism. It is a vertical side view which shows the internal structure of the guide wire of another modification.

  Hereinafter, embodiments of the present invention will be described with reference to the drawings. In all the drawings, the same reference numerals are given to the same components, and the description will be omitted as appropriate. As shown in FIG. 1, the catheter system 100 of the present embodiment includes a guide wire 1000 and a tubular catheter 2000 into which the guide wire 1000 is inserted.

  The guide wire 1000 of the present embodiment guides the catheter 2000 of the catheter system 100. For this reason, as shown in FIGS. 2 and 3, the guide wire 1000 of the present embodiment is slidably inserted into the hollow and hollow wire body 1100 and the hollow interior of the wire body 1100, so that the mutual The operation cable 1200 eccentrically connected at the most distal ends 1114 and 1210 and connected by welding or adhesion, and the proximal end portion 1220 of the operation cable 1200 are slid to bend at least the distal end portion 1110 of the wire body 1100. A bending operation mechanism 1300.

  More specifically, the wire body 1100 has a distal end portion 1110 divided into three bendable portions 1111 to 1113 in a distal-to-proximal direction. The bending ratios of 1111 to 1113 are different.

  For this reason, the wire body 1100 has an uneven bending ratio in the direction from the distal to the proximal. In the present embodiment, the three bendable portions 1111 to 1113 are formed to have the same length in the linear direction, for example.

  Moreover, the wire main body 1100 consists of winding coils, such as stainless steel, a nickel titanium alloy, steel, titanium, etc., for example, and the three bendable parts 1111 to 1113 differ in the winding pitch.

  In the guide wire 1000 of the present embodiment, the winding pitches of the three bendable portions 1111 to 1113 are dense, coarse, and dense in the direction from the distal to the proximal. In the guide wire 1000 according to the present embodiment, the portion proximal to the bendable portions 1111 to 1113 is composed of a winding coil wound most closely.

  The bending operation mechanism 1300 includes a tube-shaped handle portion 1310 formed at the proximal end portion of the guide wire 1000, and an operation knob that is slidably mounted in the front-rear direction and connected to the operation cable 1200. 1320.

  Further, in the guide wire 1000 of the present embodiment, a core material 1400 that is sharper toward the distal side in the bendable portions 1111 to 1113 is inserted into the hollow interior of the wire body 1100. This core material 1400 also has the most distal end 1410 connected to the most distal end 1114 of the operation cable 1200 by welding or bonding.

  As shown in FIGS. 3 and 4, the core material 1400 has a concave groove 1420 formed on the outer peripheral surface, and an operation cable 1200 is slidably inserted therethrough. As shown in FIG. 4, the outer peripheral surface of the core material 1400 is coated with a resin layer 1430.

  This resin layer 1430 has physical characteristics that suppress wear compared to a state in which the core material 1400 is in direct contact with the inner peripheral surface of the wire body 1100. Such a resin layer 1430 is made of, for example, a fluorine-based polymer material such as polyetheretherketone (PEEK), polysulfone (PSF), polytetrafluoroethylene (PTFE), or polyvinylidene fluoride (PVDF), silicon resin, or the like. Is formed.

  In the configuration as described above, in the guide wire 1000 of the present embodiment, as shown in FIG. 3, the operation cable 1200 is slidably inserted into the hollow interior of the wire body 1100 that is bendable and hollow.

  The operation cable 1200 is eccentrically connected to the wire body 1100 at the most distal end 1210, and the proximal end portion 1220 of the operation cable 1200 is slid by the bending operation mechanism 1300 to be at least the distal end of the wire body 1100. Part 1110 is bent.

  The guide wire 1000 is inserted into a tubular catheter 2000 and used as the catheter system 100. In this catheter system 100, the distal end portion 1110 of the guide wire 1000 is freely bent by manual operation of the bending operation mechanism 1300 of the proximal end portion 1220. Therefore, the operability for guiding the catheter 2000 to a complex shaped blood vessel is good.

  Moreover, in the guide wire 1000 of the present embodiment, the distal end portion 1110 of the wire body 1100 is divided into three bendable portions 1111 to 1113 in the direction from the distal to the proximal, and the three bendable portions 1111 are divided. The bending ratio of ˜1113 is different.

  Therefore, as shown in FIGS. 5A and 5B, when the bending operation mechanism 1300 is manually operated, tension is generated in the operation cable 1200 that is eccentrically connected to the most distal end 1114 of the wire body 1100. To do.

  For this reason, only the most distal first bendable portion 1111 is initially curved in an arc shape. This is due to a difference in winding pitch between the bendable portions 1111 to 1113 and a difference in diameter of the core material 1400.

  Next, when the bending operation mechanism 1300 is further manually operated, the second bendable portion 1112 is large as shown in FIG. 5C in a state where the first bendable portion 1111 is curved in a small-diameter arc shape. Curved in a circular arc shape.

  Further, when the bending operation mechanism 1300 is manually operated, the first bendable portion 1111 is curved in a small-diameter arc shape, and the second bendable portion 1112 is curved in a large-diameter arc shape, and the nearest third position is bent. The bendable portion 1113 is curved into a small-diameter arc.

  These are also caused by a difference in winding pitch between the bendable parts 1111 to 1113 and a difference in diameter of the core material 1400. For this reason, the guide wire 1000 of the present embodiment can easily invade a blood vessel having a complicated structure, which has been difficult in the past. Therefore, the conventional general catheter 2000 can be guided well to a blood vessel having a complicated structure.

  In addition, the wire main body 1100 of the guide wire 1000 is formed of a wound coil, and the three bendable parts 1111 to 1111 as described above are combined by making the winding pitch different and making the diameter of the core material 1400 different. 1113 stepwise bending is realized. For this reason, the bendable parts 1111 to 1113 that are bent in order at a predetermined ratio can be realized with a simple structure.

  The present invention is not limited to the above-described embodiment, and includes various modifications and improvements as long as the object of the present invention is achieved. For example, in the above-described embodiment, stepwise bending of the three bendable portions 1111 to 1113 can be performed by combining the winding pitch of the wire main body 1100 made of a winding coil with the diameter of the core material 1400 being different. Illustrated to realize.

  However, the stepwise bending of the bendable parts 1111 to 1113 can be made different in the winding pitch of the wire body 1100 made of a wound coil. In this case, the diameter of the core material may be made uniform, and only the winding pitch of the bendable portions 1111 to 1113 may be changed stepwise (not shown).

  Further, stepwise bending of the bendable parts 1111 to 1113 can be realized by making the diameter of the core material 1400 different. In this case, the winding pitch of the bendable parts 1111 to 1113 may be made uniform, and the diameter of the core material 1400 may be changed sharply stepwise at the positions of the bendable parts 1111 to 1113 (not shown).

  Further, the winding diameter may be different between the bendable portions 1111 to 1113. Furthermore, the winding diameter of the winding coil forming the wire body 1100 may be different for each of the bendable parts 1111 to 1113 (both not shown).

  Furthermore, in the said form, the winding pitch of the wire main body 1100 was varied, and it illustrated that the three bendable parts 1111 to 1113 from which a bending ratio differs were formed. However, the number of bendable portions having different bending ratios may be four or more or two (not shown).

  Moreover, in the said form, it illustrated that the three bendable parts 1111 to 1113 were formed in the same length in the linear direction. However, the lengths of the bendable portions 1111 to 1113 in the linear direction may be different.

  For example, the first bendable portion 1111 is formed in the shortest length and the third bendable portion 1113 is formed in the longest length. Conversely, the first bendable portion 1111 is formed in the longest length and the third bendable portion 1111 is formed in the longest length. It can be assumed that the bendable portion 1113 is formed as short as possible.

  Furthermore, the lengths of the three bendable parts 1111 to 1113 may be 54> 53> 55, etc. (none is shown). By setting the ratio of the bendable portions 1111 to 1113 as described above, it becomes easy to deal with various types of blood vessels, for example.

  Furthermore, in the said form, it illustrated that the wire main body 1100 consists of winding coils. However, such a wire body can be formed of a resin tube. In that case, a plurality of bendable parts having different bending ratios can be formed by, for example, a difference in film thickness of the resin tube.

  More specifically, it is assumed that the film body at the distal end of the wire body has a thin film, a thick film, and a thin film in the distal to proximal direction to form three bendable parts. Yes (not shown).

  Moreover, in the said form, the ditch | groove 1420 was formed in the outer peripheral surface of the core material 1400, and it illustrated that the resin layer 1430 was formed in the outer peripheral surface. However, like the guide wire 3000 illustrated in FIG. 6, a thick resin layer 3100 is formed on the surface of the core material 1400, and a concave groove (not shown) or a through hole 3101 is formed therein to operate the operation cable. 1200 may be slidably inserted.

  Such a resin layer 3100 is formed of, for example, a thermoplastic polymer. Examples include PI, PAI, PET (Polyethylene Terephthalate), polyethylene (PE), polyamide (PA), nylon elastomer, polyurethane (PU), ethylene-vinyl acetate resin (EVA), polyvinyl chloride (PVC), or polypropylene. (PP) or the like can be used.

  The concave groove (not shown) and the through-hole 3101 of the resin layer 3100 are co-extruded with a hollow tube (not shown) previously formed into a tube shape when the resin layer 3100 is extruded together with the core material 1400. It can be formed by molding.

  For such a hollow tube, a thermoplastic polymer material having high heat resistance, flexibility and slidability is suitably used. Specifically, a fluorine-based polymer material such as PTFE (Polytetrafluoroethylene), PFA (perfluoropolyalkylene polymer resin), or tetrafluoroethylene / hexafluoropropylene copolymer (FEP) can be used.

  In addition, non-fluorine such as PI, PAI, polysulfone (PSF), polyethersulfone (PES), polyphenylene sulfide (PPS), polyetheretherketone (PEEK), polyetherimide (PEI) or liquid crystal polymer (LCP) System polymer materials can also be used.

  Further, in the above embodiment, only one operation cable 1200 is inserted inside the wire main body 1100 of the guide wire 1000, and the bendable portions 1111 to 1113 are bent only in one direction.

  However, a plurality of such operation cables 1200 may be provided, and the bendable portions 1111 to 1113 may be bent in a plurality of directions (not shown). For example, like the guide wire 4000 illustrated in FIGS. 7 and 8, the pair of operation cables 1200 and 4200 may be disposed at opposite positions with the axis as the center.

  In this case, as shown in FIG. 8, since the bendable parts 1111 to 1113 can be bent to both sides by manual operation of the pair of bending operation mechanisms 1300 and 4300, the degree of freedom in guiding the catheter 2000 is further improved. Can be made. Further, by simultaneously operating the pair of bending operation mechanisms 1300 and 4300, the bending degree of the bendable portions 1111 to 1113 can be slightly changed.

  Furthermore, it can be assumed that a plurality of operation cables 1200 are inserted into the wire body 1100 of the guide wire 1000 and the tips thereof are connected to the tips of the bendable portions 1111 to 1113.

  For example, like the guide wire 5000 illustrated in FIG. 9, the tip of the first operation cable 5100 is connected to the tip of the first bendable portion 1111, and the second operation cable 5200 is connected in the same direction from the axis. It can also be connected to the tip of the second bendable part 1112.

  In this case, as shown in FIG. 10, by the selective manual operation of the first / second bending operation mechanisms 1300 and 5300, the first bendable portion of the guide wire 5000 as shown in FIG. 10 (b). In addition to bending only 1111, the first bendable portion 1111 and the second bendable portion 1112 can be bent as shown in FIG. 10 (c), as shown in FIG. 10 (d). The second bendable portion 1112 can be bent without bending the first bendable portion 1111.

  Note that, as described above, inserting the first / second operation cables 5100 and 5200 in the same direction from the axis of the wire main body 1100 is performed on the outer peripheral surface of the core material 1400 as described above. A concave groove 1420 is formed to allow the operation cable 5100 to be inserted, and a concave groove (not shown) or a through hole 3101 is formed in the thick resin layer 3100 formed on the outer peripheral surface thereof to allow the operation cable 5200 to be inserted. That's fine.

  On the other hand, like the guide wire 6000 illustrated in FIG. 12, the tip of the first operation cable 6100 is connected to the tip of the first bendable part 1111 and the second operation cable 6200 is connected in the opposite direction from the axis. It can also be connected to the tip of the second bendable part 1112.

  In this case, as shown in FIG. 13, by the selective manual operation of the first / second bending operation mechanisms 1300 and 6300, as shown in FIG. In addition to bending only 1111, the second bendable part 1112 can be bent without bending the first bendable part 1111, as shown in FIG. 13 (c). As shown, the first bendable portion 1111 and the second bendable portion 1112 can be bent in opposite directions.

  Of course, the configuration of the plurality of operation cables 5100, 5200, 6100, 6200 as described above may be combined. This makes it possible to insert a guide wire through a blood vessel having a very complicated shape (not shown).

  Further, in the above embodiment, the operation cable 1200 is stretched linearly inside the wire body 1100, and the bendable portions 1111 to 1113 are bent as plane curves.

  However, like the guide wire 7000 illustrated in FIG. 14, the bendable portions 1111 to 1113 are spirally wound by winding the operation cable 1200 around the core material 1400 in the bendable portions 1111 to 1113. It can also be bent as a curve (not shown). Thereby, even if it does not rotate the guide wire 7000 by proximal operation, the distal end part can be turned.

  In this case, a concave groove 1420 into which the operation cable 1200 is inserted may be formed in a spiral shape on the surface of the core material 1400 at the positions of the bendable portions 1111 to 1113. In addition, it is preferable to form the concave groove 1420 in a straight line so that unnecessary bending does not occur in a portion proximal to the bendable portions 1111 to 1113.

DESCRIPTION OF SYMBOLS 100 Catheter system 1000 Guide wire 1100 Wire main body 1110 Distal end part 1111 Bendable part 1112 Bendable part 1113 Bendable part 1114 The most distal end 1200 Operation cable 1210 The most distal end 1220 The proximal end part 1300 Bending operation mechanism 1310 Handle Portion 1320 Operation knob 1400 Core material 1410 Distal end 1420 Concave groove 1430 Resin layer 2000 Catheter 3000 Guide wire 3100 Resin layer 3101 Through hole 4000 Guide wire 4200 Operation cable 4300 Bending operation mechanism 5000 Guide wire 5100 Operation cable 5200 Operation cable 5300 Bending operation Mechanism 6000 Guide wire 6100 Operation cable 6200 Operation cable 6300 Bending operation mechanism 7000 Guide wire

Claims (9)

A guide wire for guiding the catheter,
A bendable, hollow wire body,
An operation cable that is slidably inserted into the hollow interior of the wire body and is eccentrically connected at the distal ends of each other;
A bending operation mechanism for sliding the proximal end of the operation cable to bend the distal end of the wire body;
Having a guide wire.   The guide wire according to claim 1, wherein the wire body is formed to have an uneven bending ratio in a direction from the distal end to the proximal end of the distal end portion.   The wire main body is divided into a plurality of bendable bendable portions in a distal-to-proximal direction at the distal end, and the bend ratios of the bendable portions are different from each other. Guide wire as described.   The guide wire according to claim 3, wherein the wire body is formed of a winding coil, and a plurality of the bendable portions have different winding pitches of the winding coil.   5. The guide wire according to claim 4, wherein the wire body has at least three bendable portions that are dense, coarse, and dense in a winding direction from a distal direction to a proximal direction.   The guide wire according to any one of claims 1 to 5, further comprising a core material that is inserted into a hollow inside of the wire main body and is sharper toward the distal side within the bendable portion.   The guide wire according to claim 6, wherein the operation cable is slidably inserted into a concave groove formed in an outer peripheral surface of the core material.   The guide according to claim 6, wherein a resin layer is formed on an outer peripheral surface of the core material, and the operation cable is slidably inserted into at least one of a concave groove or a through hole formed in the resin layer. Wire. A guide wire according to claims 1 to 8,
A tubular catheter into which the guide wire is inserted;
A catheter system.

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