JP2011042682A5 - - Google Patents

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Publication number
JP2011042682A5
JP2011042682A5 JP2010242734A JP2010242734A JP2011042682A5 JP 2011042682 A5 JP2011042682 A5 JP 2011042682A5 JP 2010242734 A JP2010242734 A JP 2010242734A JP 2010242734 A JP2010242734 A JP 2010242734A JP 2011042682 A5 JP2011042682 A5 JP 2011042682A5
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JP
Japan
Prior art keywords
aqueous preparation
hyaluronic acid
acid
thickener
thickener according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2010242734A
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Japanese (ja)
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JP2011042682A (en
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Publication date
Application filed filed Critical
Priority to JP2010242734A priority Critical patent/JP2011042682A/en
Priority claimed from JP2010242734A external-priority patent/JP2011042682A/en
Publication of JP2011042682A publication Critical patent/JP2011042682A/en
Publication of JP2011042682A5 publication Critical patent/JP2011042682A5/ja
Pending legal-status Critical Current

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Claims (6)

ホウ酸が遊離酸として０．５〜２重量％配合されることを特徴とする、ヒアルロン酸を含有する水性製剤の増粘剤。A thickener for an aqueous preparation containing hyaluronic acid, characterized in that boric acid is blended as a free acid in an amount of 0.5 to 2 wt%. ヒアルロン酸がナトリウム塩である請求項１記載の増粘剤。The thickener according to claim 1, wherein the hyaluronic acid is a sodium salt. 水性製剤がヒアルロン酸を０．００１〜０．５重量％含有する請求項１記載の増粘剤。The thickener according to claim 1, wherein the aqueous preparation contains 0.001 to 0.5% by weight of hyaluronic acid. 水性製剤のｐＨが５〜７．５である請求項１記載の増粘剤。The thickener according to claim 1, wherein the pH of the aqueous preparation is 5 to 7.5. ホウ酸およびグルコン酸クロルヘキシジンを配合することを特徴とする、粘度を増加したヒアルロン酸含有水性製剤の製造方法。A method for producing an aqueous preparation containing hyaluronic acid having an increased viscosity, comprising boric acid and chlorhexidine gluconate. ホウ酸およびグルコン酸クロルヘキシジンを配合することを特徴とする、粘度を増加したヒアルロン酸含有水性製剤の粘度低下抑制方法。A method for suppressing a decrease in viscosity of a hyaluronic acid-containing aqueous preparation with increased viscosity, comprising boric acid and chlorhexidine gluconate.
JP2010242734A 1997-05-20 2010-10-28 Thickener for aqueous preparation Pending JP2011042682A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2010242734A JP2011042682A (en) 1997-05-20 2010-10-28 Thickener for aqueous preparation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14731597 1997-05-20
JP2010242734A JP2011042682A (en) 1997-05-20 2010-10-28 Thickener for aqueous preparation

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP12865898A Division JPH1143446A (en) 1997-05-20 1998-05-12 Viscosity-increasing agent for aqueous preparation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013219722A Division JP5886260B2 (en) 1997-05-20 2013-10-23 Method for inhibiting thickening and viscosity reduction of hyaluronic acid containing aqueous preparation

Publications (2)

Publication Number Publication Date
JP2011042682A JP2011042682A (en) 2011-03-03
JP2011042682A5 true JP2011042682A5 (en) 2011-12-01

Family

ID=43830352

Family Applications (4)

Application Number Title Priority Date Filing Date
JP2010242734A Pending JP2011042682A (en) 1997-05-20 2010-10-28 Thickener for aqueous preparation
JP2013219722A Expired - Lifetime JP5886260B2 (en) 1997-05-20 2013-10-23 Method for inhibiting thickening and viscosity reduction of hyaluronic acid containing aqueous preparation
JP2015192424A Pending JP2016014053A (en) 1997-05-20 2015-09-30 Thickened hyaluronic acid-containing aqueous formulation
JP2016211210A Expired - Lifetime JP6156762B2 (en) 1997-05-20 2016-10-28 Thickening and viscosity reduction inhibitor for hyaluronic acid-containing aqueous preparations

Family Applications After (3)

Application Number Title Priority Date Filing Date
JP2013219722A Expired - Lifetime JP5886260B2 (en) 1997-05-20 2013-10-23 Method for inhibiting thickening and viscosity reduction of hyaluronic acid containing aqueous preparation
JP2015192424A Pending JP2016014053A (en) 1997-05-20 2015-09-30 Thickened hyaluronic acid-containing aqueous formulation
JP2016211210A Expired - Lifetime JP6156762B2 (en) 1997-05-20 2016-10-28 Thickening and viscosity reduction inhibitor for hyaluronic acid-containing aqueous preparations

Country Status (1)

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JP (4) JP2011042682A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013112628A (en) * 2011-11-28 2013-06-10 Senju Pharmaceut Co Ltd Ophthalmic composition for animal
JP6603785B2 (en) * 2017-12-08 2019-11-06 千寿製薬株式会社 Aqueous solution containing water-soluble polymer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5261183A (en) * 1975-11-15 1977-05-20 Kouji Kobayashi Manufacture of hydrated gel
JPS5857319A (en) * 1981-09-30 1983-04-05 Green Cross Corp:The High-viscosity hyaluronic acid preparation
US4826719A (en) * 1986-07-15 1989-05-02 H. B. Fuller Company Fast setting starch-based corrugating adhesive having fully hydrolyzed cold water insoluble polyvinyl alcohol component
SG64856A1 (en) * 1988-08-04 1999-05-25 Novartis Ag A method of preserving ophthalimic solutions and composition thereof
SU1623991A1 (en) * 1989-05-06 1991-01-30 Всесоюзный научно-исследовательский институт текстильно-галантерейной промышленности Process for stabilization of gialuronic acid
JP3050898B2 (en) * 1990-07-06 2000-06-12 千寿製薬株式会社 Aqueous pharmaceutical preparation
JP4157988B2 (en) * 1996-07-12 2008-10-01 ロート製薬株式会社 Water-soluble preparations with no contraindications

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