JP2010527917A5 - - Google Patents

Download PDF

Info

Publication number
JP2010527917A5
JP2010527917A5 JP2010506715A JP2010506715A JP2010527917A5 JP 2010527917 A5 JP2010527917 A5 JP 2010527917A5 JP 2010506715 A JP2010506715 A JP 2010506715A JP 2010506715 A JP2010506715 A JP 2010506715A JP 2010527917 A5 JP2010527917 A5 JP 2010527917A5
Authority
JP
Japan
Prior art keywords
ifnα
expression profile
inducible
patient
marker expression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2010506715A
Other languages
English (en)
Japanese (ja)
Other versions
JP5411129B2 (ja
JP2010527917A (ja
Filing date
Publication date
Priority claimed from PCT/US2007/024941 external-priority patent/WO2008070135A2/en
Application filed filed Critical
Priority claimed from PCT/US2008/062646 external-priority patent/WO2008137838A2/en
Publication of JP2010527917A publication Critical patent/JP2010527917A/ja
Publication of JP2010527917A5 publication Critical patent/JP2010527917A5/ja
Application granted granted Critical
Publication of JP5411129B2 publication Critical patent/JP5411129B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2010506715A 2007-05-03 2008-05-05 インターフェロンα誘導性薬力学的マーカー Expired - Fee Related JP5411129B2 (ja)

Applications Claiming Priority (23)

Application Number Priority Date Filing Date Title
US92421907P 2007-05-03 2007-05-03
US92422007P 2007-05-03 2007-05-03
US60/924,220 2007-05-03
US60/924,219 2007-05-03
US92458407P 2007-05-21 2007-05-21
US60/924,584 2007-05-21
US96018707P 2007-09-19 2007-09-19
US60/960,187 2007-09-19
US99617407P 2007-11-05 2007-11-05
US99617607P 2007-11-05 2007-11-05
US60/996,174 2007-11-05
US60/996,176 2007-11-05
US99621907P 2007-11-06 2007-11-06
US60/996,219 2007-11-06
US99682007P 2007-12-06 2007-12-06
PCT/US2007/024941 WO2008070135A2 (en) 2006-12-06 2007-12-06 Methods of treating systemic lupus erythematosus
USPCT/US2007/024941 2007-12-06
US60/996,820 2007-12-06
USPCT/US2007/024947 2007-12-06
PCT/US2007/024947 WO2008070137A2 (en) 2006-12-06 2007-12-06 Interferon alpha-induced pharmacodynamic markers
US696308P 2008-02-08 2008-02-08
US61/006,963 2008-02-08
PCT/US2008/062646 WO2008137838A2 (en) 2007-05-03 2008-05-05 Interferon alpha-induced pharmacodynamic markers

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2013230753A Division JP2014064577A (ja) 2007-05-03 2013-11-07 インターフェロンα誘導性薬力学的マーカー

Publications (3)

Publication Number Publication Date
JP2010527917A JP2010527917A (ja) 2010-08-19
JP2010527917A5 true JP2010527917A5 (https=) 2011-06-16
JP5411129B2 JP5411129B2 (ja) 2014-02-12

Family

ID=39944226

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2010506714A Withdrawn JP2010526107A (ja) 2007-05-03 2008-05-05 自己免疫疾患の自己抗体マーカー
JP2010506715A Expired - Fee Related JP5411129B2 (ja) 2007-05-03 2008-05-05 インターフェロンα誘導性薬力学的マーカー
JP2013230753A Pending JP2014064577A (ja) 2007-05-03 2013-11-07 インターフェロンα誘導性薬力学的マーカー

Family Applications Before (1)

Application Number Title Priority Date Filing Date
JP2010506714A Withdrawn JP2010526107A (ja) 2007-05-03 2008-05-05 自己免疫疾患の自己抗体マーカー

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2013230753A Pending JP2014064577A (ja) 2007-05-03 2013-11-07 インターフェロンα誘導性薬力学的マーカー

Country Status (6)

Country Link
US (2) US9181345B2 (https=)
EP (2) EP2076590A4 (https=)
JP (3) JP2010526107A (https=)
AU (2) AU2008247395A1 (https=)
CA (2) CA2685147A1 (https=)
WO (2) WO2008137838A2 (https=)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2240781T3 (en) 2008-01-18 2018-03-26 Harvard College METHODS FOR DETECTING DISEASE OR STATE SIGNATURES IN BODY FLUIDS
WO2011109440A1 (en) 2010-03-01 2011-09-09 Caris Life Sciences Luxembourg Holdings Biomarkers for theranostics
US20120251546A1 (en) * 2009-09-03 2012-10-04 Medimmune Llc Type 1 inteferon diagnostic
WO2011127219A1 (en) 2010-04-06 2011-10-13 Caris Life Sciences Luxembourg Holdings Circulating biomarkers for disease
EP2596134B1 (en) 2010-07-23 2020-04-08 President and Fellows of Harvard College Methods of detecting diseases or conditions using phagocytic cells
AU2011280997A1 (en) 2010-07-23 2013-02-28 President And Fellows Of Harvard College Methods of detecting autoimmune or immune-related diseases or conditions
WO2012012693A2 (en) 2010-07-23 2012-01-26 President And Fellows Of Harvard College Methods for detecting signatures of disease or conditions in bodily fluids
CA2806304A1 (en) 2010-07-23 2012-01-26 President And Fellows Of Harvard College Methods of detecting prenatal or pregnancy-related diseases or conditions
WO2012039161A1 (ja) * 2010-09-22 2012-03-29 国立大学法人 千葉大学 新規血管炎の検査方法および検査用試薬
GB201017520D0 (en) * 2010-10-15 2010-12-01 Sense Proteomic Ltd Biomarkers
AU2013204880B2 (en) * 2011-04-26 2016-11-24 Genentech, Inc. Compositions and method for treating autoimmune diseases
AU2012249601A1 (en) * 2011-04-26 2013-05-09 Genentech, Inc. Compositions and method for treating autoimmune diseases
WO2014079966A1 (en) * 2012-11-23 2014-05-30 Medizinische Hochschule Hannover Analysis for adult-onset still's disease
CN114176586B (zh) * 2012-12-14 2025-01-07 明德拉公司 用于检测和获取生物标志物的方法和装置
EP2965077B1 (en) 2013-03-09 2022-07-13 Harry Stylli Methods of detecting cancer
US11585814B2 (en) 2013-03-09 2023-02-21 Immunis.Ai, Inc. Methods of detecting prostate cancer
IL278381B2 (en) * 2013-12-06 2024-08-01 Celgene Corp Methods for determining the effectiveness of a drug for the treatment of diffuse large B-cell lymphoma, multiple myeloma, and myeloid cancer
MA40636A (fr) 2014-09-11 2015-09-11 Colleen Kelly Procédés pour détecter le cancer de la prostate
JP7308034B2 (ja) 2016-07-01 2023-07-13 リゾルブ セラピューティクス， エルエルシー 最適化二重ヌクレアーゼ融合物および方法
BR112020003670A2 (pt) 2017-08-22 2020-09-01 Sanabio, Llc receptores de interferon solúveis e usos dos mesmos
US12331320B2 (en) 2018-10-10 2025-06-17 The Research Foundation For The State University Of New York Genome edited cancer cell vaccines
EA202191133A1 (ru) * 2018-10-26 2021-07-12 Янссен Байотек, Инк. Сигнатуры интерферона типа i и способы их применения
CN110747190B (zh) * 2019-11-27 2021-03-09 浙江华睿生物技术有限公司 一种马来酸水合酶突变体及其应用
WO2025062016A2 (en) * 2023-09-22 2025-03-27 Merck Patent Gmbh Biomarkers for tlr inhibitor treatment
WO2026004792A1 (ja) * 2024-06-24 2026-01-02 キヤノンメディカルダイアグノスティックス株式会社 細胞性免疫応答活性を測定する方法及びそのためのキット

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0139676B1 (en) 1983-02-04 1992-11-25 Cytoclonal Pharmaceutics Inc. Production and characterization of hybridoma antibodies directed specifically against common determinant(s) present among closely related, but distinct proteins
GB8303165D0 (en) 1983-02-04 1983-03-09 Secher D S Monoclonal antibody
DE3306060A1 (de) 1983-02-22 1984-08-23 Boehringer Ingelheim International GmbH, 6507 Ingelheim Neue immunglobulin-produzierende hybridzellinien, deren verwendung und verfahren zu deren herstellung
EP0205404B1 (en) 1985-06-11 1992-07-15 Ciba-Geigy Ag Hybrid interferons
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
US5744101A (en) 1989-06-07 1998-04-28 Affymax Technologies N.V. Photolabile nucleoside protecting groups
FR2692168B1 (fr) 1992-06-16 1995-03-24 Centre Nat Rech Scient Préparation et utilisation de nouveaux systèmes colloïdaux dispersibles à base de cyclodextrine, sous forme de nanosphères.
US5888511A (en) 1993-02-26 1999-03-30 Advanced Biotherapy Concepts, Inc. Treatment of autoimmune diseases, including AIDS
US6077835A (en) 1994-03-23 2000-06-20 Case Western Reserve University Delivery of compacted nucleic acid to cells
US5972901A (en) 1994-03-23 1999-10-26 Case Western Reserve University Serpin enzyme complex receptor--mediated gene transfer
JP4285766B2 (ja) 1994-03-23 2009-06-24 オハイオ ユニバーシティ 緻密にした核酸および細胞へのデリバリ
AU749032B2 (en) 1997-06-13 2002-06-20 Johns Hopkins University, The Therapeutic nanospheres
US20050008683A1 (en) * 2000-06-29 2005-01-13 Becton Dickinson And Company Method for delivering interferons to the intradermal compartment
US20040265874A1 (en) * 2000-10-17 2004-12-30 Bio-Rad Laboratories, Inc. Pattern recognition method for diagnosis of systemic autoimmune diseases
BR0206364A (pt) * 2001-01-09 2005-08-16 Baylor Res Inst Métodos para tratar doenças auto-imunes em um indivìduo e testes diagnósticos in vitro
US7087726B2 (en) * 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies
WO2003046008A1 (en) * 2001-11-30 2003-06-05 Innogenetics N.V. Therapeutic use of antibodies and fragments thereof binding primate ifn-gamma
EP2298360A3 (en) * 2002-11-21 2011-07-13 Bayhill Therapeutics, Inc. Methods and immune modulatory nucleic acid compositions for preventing and treating disease
CN1871252A (zh) * 2003-09-05 2006-11-29 Gtc生物治疗学公司 在转基因哺乳动物奶中生产融合蛋白的方法
NZ547157A (en) * 2003-12-10 2009-07-31 Medarex Inc Interferon Alpha Antibodies and their uses
WO2006086586A2 (en) * 2005-02-10 2006-08-17 Baylor Research Institute Anti-interferon alpha monoclonal antibodies and methods for use
US20070117105A1 (en) * 2005-05-12 2007-05-24 Crow Mary K Interferon assay
US20070065844A1 (en) * 2005-06-08 2007-03-22 Massachusetts Institute Of Technology Solution-based methods for RNA expression profiling
PT2327792E (pt) * 2005-08-05 2013-11-21 Genentech Inc Métodos e composições para a detecção de distúrbios autoimunes
US7608395B2 (en) * 2005-09-15 2009-10-27 Baylor Research Institute Systemic lupus erythematosus diagnostic assay
EA015860B1 (ru) * 2005-10-13 2011-12-30 Хьюман Дженом Сайенсиз, Инк. Способы лечения аутоиммунных заболеваний при использовании антагониста нейтрокина-альфа
EP2077858A4 (en) * 2006-12-06 2011-07-20 Medimmune Llc INTERFERON ALPHA-INDUCED PHARMACODYNAMIC MARKERS
US20110287022A1 (en) * 2008-06-20 2011-11-24 Medlmmune, Llc Interferon alpha-induced pharmacodynamic markers
US20120251546A1 (en) * 2009-09-03 2012-10-04 Medimmune Llc Type 1 inteferon diagnostic

Similar Documents

Publication Publication Date Title
JP2010527917A5 (https=)
JP2010512315A5 (https=)
Powell et al. Tumor necrosis factor and its targets in the inflammatory cytokine pathway are identified as putative transcriptomic biomarkers for escitalopram response
Sypabekova et al. Electrochemical aptasensor using optimized surface chemistry for the detection of Mycobacterium tuberculosis secreted protein MPT64 in human serum
Camela et al. Towards personalized medicine in psoriasis: current progress
Waszczuk et al. Dimensional and transdiagnostic phenotypes in psychiatric genome-wide association studies
MX2014004712A (es) Metodos para mejorar el diagnostico de enfermedad inflamatoria intestinal.
Burrell et al. Re-evaluating clonal dominance in cancer evolution
Vrgoc et al. Interleukin‐17 and Toll‐like Receptor 10 genetic polymorphisms and susceptibility to large joint osteoarthritis
NZ590988A (en) Biomarkers for anti-tnf treatment in ulcerative colitis and related disorders
Qasem et al. Genetic polymorphisms in tumour necrosis factor receptors (TNFRSF1A/1B) illustrate differential treatment response to TNFα inhibitors in patients with Crohn’s disease
Flanagan et al. The Candida albicans TOR-activating GTPases Gtr1 and Rhb1 coregulate starvation responses and biofilm formation
JP2013178260A5 (https=)
Glatt et al. Elongator: transcriptional or translational regulator?
Liu et al. Functional effect of polymorphisms in the promoter of TNFAIP3 (A20) in acute pancreatitis in the Han Chinese population
Sun et al. Downregulation of microRNA‐101‐3p participates in systemic lupus erythematosus progression via negatively regulating HDAC9
Safarinejad Analysis of association between the 5‐HTTLPR and STin2 polymorphisms in the serotonin‐transporter gene and clinical response to a selective serotonin reuptake inhibitor (sertraline) in patients with premature ejaculation
JP2015502137A5 (https=)
CN103820545B (zh) 用于检测人abcg2基因突变的探针、引物及试剂盒
Moraes Holst et al. Downregulated mucosal autophagy, alpha kinase-1 and IL-17 signaling pathways in active and quiescent ulcerative colitis
Patrick et al. Large-scale functional inference for skin-expressing lncRNAs using expression and sequence information
Chen et al. Loss of BCAT1 expression is a sensitive marker for IDH-mutant diffuse glioma
Troudet et al. Gene expression and response prediction to amisulpride in the OPTiMiSE first episode psychoses
Xing et al. The role of BDNF exon I region methylation in the treatment of depression with sertraline and its clinical diagnostic value
CN102787161A (zh) 一种检测结核分枝杆菌方法及其专用引物