JP2010526995A5 - - Google Patents
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- Publication number
- JP2010526995A5 JP2010526995A5 JP2010506846A JP2010506846A JP2010526995A5 JP 2010526995 A5 JP2010526995 A5 JP 2010526995A5 JP 2010506846 A JP2010506846 A JP 2010506846A JP 2010506846 A JP2010506846 A JP 2010506846A JP 2010526995 A5 JP2010526995 A5 JP 2010526995A5
- Authority
- JP
- Japan
- Prior art keywords
- colorectal cancer
- timp
- marker
- hemoglobin
- binding agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 206010009944 Colon cancer Diseases 0.000 claims 9
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 9
- 102000005353 Tissue Inhibitor of Metalloproteinase-1 Human genes 0.000 claims 8
- 108010031374 Tissue Inhibitor of Metalloproteinase-1 Proteins 0.000 claims 8
- 239000003550 marker Substances 0.000 claims 8
- 238000000034 method Methods 0.000 claims 7
- 102000001554 Hemoglobins Human genes 0.000 claims 6
- 108010054147 Hemoglobins Proteins 0.000 claims 6
- 239000011230 binding agent Substances 0.000 claims 6
- 238000001514 detection method Methods 0.000 claims 5
- 102000014702 Haptoglobin Human genes 0.000 claims 3
- 108050005077 Haptoglobin Proteins 0.000 claims 3
- 230000015572 biosynthetic process Effects 0.000 claims 3
- 238000004581 coalescence Methods 0.000 claims 3
- 230000009870 specific binding Effects 0.000 claims 3
- 102000001109 Leukocyte L1 Antigen Complex Human genes 0.000 claims 2
- 108010069316 Leukocyte L1 Antigen Complex Proteins 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 102000013009 Pyruvate Kinase Human genes 0.000 claims 2
- 108020005115 Pyruvate Kinase Proteins 0.000 claims 2
- 239000011536 extraction buffer Substances 0.000 claims 2
- 230000027455 binding Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07009396 | 2007-05-10 | ||
| PCT/EP2008/003642 WO2008138522A1 (en) | 2007-05-10 | 2008-05-07 | Use of timp-1 as a marker for colorectal cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010526995A JP2010526995A (ja) | 2010-08-05 |
| JP2010526995A5 true JP2010526995A5 (https=) | 2011-02-17 |
Family
ID=38521224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010506846A Withdrawn JP2010526995A (ja) | 2007-05-10 | 2008-05-07 | 結腸直腸癌のマーカーとしてのｔｉｍｐ−１の使用 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20100159479A1 (https=) |
| EP (1) | EP2145190A1 (https=) |
| JP (1) | JP2010526995A (https=) |
| CN (1) | CN101680898A (https=) |
| CA (1) | CA2684024A1 (https=) |
| WO (1) | WO2008138522A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE521894T1 (de) * | 2007-11-20 | 2011-09-15 | Hoffmann La Roche | Verfahren zur beurteilung von kolorektalem krebs anhand einer stuhlprobe durch verwendung einer marker-kombination aus calprotectin und einem hämoglobin/haptoglobin-komplex |
| EP2239577A1 (en) * | 2009-04-07 | 2010-10-13 | Vereniging voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek en Patiëntenzorg | Protein-based methods and compositions for the diagnosis of colorectal adenocarcinoma |
| CN103140760B (zh) | 2010-07-14 | 2016-01-27 | 联邦科学与工业研究组织 | 结肠直肠癌的诊断 |
| CN104178562B (zh) * | 2013-05-21 | 2018-11-09 | 生物梅里埃股份公司 | 一种大肠癌预后试剂盒 |
| EP3073268A1 (en) * | 2015-03-27 | 2016-09-28 | Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts | Biomarker panel for diagnosing cancer |
| CN105891372B (zh) * | 2016-06-12 | 2018-11-02 | 上海阿趣生物科技有限公司 | 原发性肝癌伴胆管癌栓生物标志物及其用途 |
| CN113122544A (zh) * | 2021-04-25 | 2021-07-16 | 杭州广科安德生物科技有限公司 | 一种特异性结合timp1蛋白的核酸适配体及其应用 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5324636A (en) * | 1991-07-24 | 1994-06-28 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University | Radiorespirometer and method of use |
| US5455160A (en) * | 1993-05-27 | 1995-10-03 | Fagerhol; Magne K. | Diagnostic test and kit for disease or disorders in the digestive system |
| JP2000510949A (ja) * | 1996-04-26 | 2000-08-22 | チルドレンズ メディカル センター コーポレーション | 組織のリモデリングに関連した状態のための非観血的酵素スクリーン |
| US7374886B2 (en) * | 1999-04-09 | 2008-05-20 | Rigshospitalet | Tissue inhibitor of matrix metalloproteinases type-1 (TIMP-1) as a cancer marker and postoperative marker for minimal residual disease or recurrent disease in patients with a prior history of cancer |
| NZ515311A (en) * | 1999-04-09 | 2002-11-26 | Rigshospitalet | Mass screening and highly specific early identification of colorectal or metastatic breast cancer by measuring TIMP-1 tissue inhibitor |
| WO2002031507A2 (en) * | 2000-10-13 | 2002-04-18 | Children's Medical Center Corporation | Non-invasive enzyme screen for tissue remodelling-associated conditions |
| WO2005095978A1 (en) * | 2004-03-30 | 2005-10-13 | Roche Diagnostics Gmbh | Pyrroline-5-carboxylate reductase as a marker for colorectal concer |
| FR2919065B1 (fr) * | 2007-07-19 | 2009-10-02 | Biomerieux Sa | Procede de dosage de l'apolipoproteine ai pour le diagnostic in vitro du cancer colorectal |
| FR2919063B1 (fr) * | 2007-07-19 | 2009-10-02 | Biomerieux Sa | Procede de dosage du leucocyte elastase inhibitor pour le diagnostic in vitro du cancer colorectal. |
-
2008
- 2008-05-07 CN CN200880015574A patent/CN101680898A/zh active Pending
- 2008-05-07 CA CA002684024A patent/CA2684024A1/en not_active Abandoned
- 2008-05-07 EP EP08758392A patent/EP2145190A1/en not_active Withdrawn
- 2008-05-07 JP JP2010506846A patent/JP2010526995A/ja not_active Withdrawn
- 2008-05-07 WO PCT/EP2008/003642 patent/WO2008138522A1/en not_active Ceased
-
2009
- 2009-11-06 US US12/613,760 patent/US20100159479A1/en not_active Abandoned
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