JP2010526995A - 結腸直腸癌のマーカーとしてのtimp−1の使用 - Google Patents

結腸直腸癌のマーカーとしてのtimp−1の使用 Download PDF

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Publication number
JP2010526995A
JP2010526995A JP2010506846A JP2010506846A JP2010526995A JP 2010526995 A JP2010526995 A JP 2010526995A JP 2010506846 A JP2010506846 A JP 2010506846A JP 2010506846 A JP2010506846 A JP 2010506846A JP 2010526995 A JP2010526995 A JP 2010526995A
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JP
Japan
Prior art keywords
timp
stool
colorectal cancer
marker
sample
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Withdrawn
Application number
JP2010506846A
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English (en)
Japanese (ja)
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JP2010526995A5 (cg-RX-API-DMAC7.html
Inventor
ロリンガー,ウォルフガング
アンドレス,ヘルベルト
ガルツァレック,ウルズラ
ガイスタンガー,アンドレア
ハイス,ペーター
カール,ヨハン
クラウゼ,フリーデマン
ヴィルト,ノルベルト
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of JP2010526995A publication Critical patent/JP2010526995A/ja
Publication of JP2010526995A5 publication Critical patent/JP2010526995A5/ja
Withdrawn legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407Specifically defined cancers
    • G01N33/57419Specifically defined cancers of colon
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81Protease inhibitors
    • G01N2333/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/8146Metalloprotease (E.C. 3.4.24) inhibitors, e.g. tissue inhibitor of metallo proteinase, TIMP

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2010506846A 2007-05-10 2008-05-07 結腸直腸癌のマーカーとしてのtimp−1の使用 Withdrawn JP2010526995A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07009396 2007-05-10
PCT/EP2008/003642 WO2008138522A1 (en) 2007-05-10 2008-05-07 Use of timp-1 as a marker for colorectal cancer

Publications (2)

Publication Number Publication Date
JP2010526995A true JP2010526995A (ja) 2010-08-05
JP2010526995A5 JP2010526995A5 (cg-RX-API-DMAC7.html) 2011-02-17

Family

ID=38521224

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2010506846A Withdrawn JP2010526995A (ja) 2007-05-10 2008-05-07 結腸直腸癌のマーカーとしてのtimp−1の使用

Country Status (6)

Country Link
US (1) US20100159479A1 (cg-RX-API-DMAC7.html)
EP (1) EP2145190A1 (cg-RX-API-DMAC7.html)
JP (1) JP2010526995A (cg-RX-API-DMAC7.html)
CN (1) CN101680898A (cg-RX-API-DMAC7.html)
CA (1) CA2684024A1 (cg-RX-API-DMAC7.html)
WO (1) WO2008138522A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009065551A1 (en) * 2007-11-20 2009-05-28 Roche Diagnostics Gmbh Method of assessing colorectal cancer from a stool sample by use of the marker combination calprotectin and hemoglobin/haptoglobin complex
EP2239577A1 (en) * 2009-04-07 2010-10-13 Vereniging voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek en Patiëntenzorg Protein-based methods and compositions for the diagnosis of colorectal adenocarcinoma
US20130345322A1 (en) * 2010-07-14 2013-12-26 Commonwealth Scientific And Industrial Research Organisation Diagnostic for colorectal cancer
EP3000897B1 (en) * 2013-05-21 2019-10-16 Biomérieux Colorectal cancer prognosis agent kit
EP3073268A1 (en) * 2015-03-27 2016-09-28 Deutsches Krebsforschungszentrum Stiftung des Öffentlichen Rechts Biomarker panel for diagnosing cancer
CN105891372B (zh) * 2016-06-12 2018-11-02 上海阿趣生物科技有限公司 原发性肝癌伴胆管癌栓生物标志物及其用途
CN113122544A (zh) * 2021-04-25 2021-07-16 杭州广科安德生物科技有限公司 一种特异性结合timp1蛋白的核酸适配体及其应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5324636A (en) * 1991-07-24 1994-06-28 The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University Radiorespirometer and method of use
US5455160A (en) * 1993-05-27 1995-10-03 Fagerhol; Magne K. Diagnostic test and kit for disease or disorders in the digestive system
AU2681997A (en) * 1996-04-26 1997-11-19 Children's Medical Center Corporation Non-invasive enzyme screen for tissue remodelling-associated conditions
WO2000062070A2 (en) * 1999-04-09 2000-10-19 Rigshospitalet Tissue inhibitor of matrix metalloproteinases type-1 (timp-1) as a cancer marker
US7374886B2 (en) * 1999-04-09 2008-05-20 Rigshospitalet Tissue inhibitor of matrix metalloproteinases type-1 (TIMP-1) as a cancer marker and postoperative marker for minimal residual disease or recurrent disease in patients with a prior history of cancer
WO2002031507A2 (en) * 2000-10-13 2002-04-18 Children's Medical Center Corporation Non-invasive enzyme screen for tissue remodelling-associated conditions
WO2005095978A1 (en) * 2004-03-30 2005-10-13 Roche Diagnostics Gmbh Pyrroline-5-carboxylate reductase as a marker for colorectal concer
FR2919065B1 (fr) * 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage de l'apolipoproteine ai pour le diagnostic in vitro du cancer colorectal
FR2919063B1 (fr) * 2007-07-19 2009-10-02 Biomerieux Sa Procede de dosage du leucocyte elastase inhibitor pour le diagnostic in vitro du cancer colorectal.

Also Published As

Publication number Publication date
CN101680898A (zh) 2010-03-24
US20100159479A1 (en) 2010-06-24
CA2684024A1 (en) 2008-11-20
WO2008138522A1 (en) 2008-11-20
EP2145190A1 (en) 2010-01-20

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