JP2010510771A - 翻訳後修飾の検出のための方法 - Google Patents

翻訳後修飾の検出のための方法 Download PDF

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JP2010510771A
JP2010510771A JP2009537717A JP2009537717A JP2010510771A JP 2010510771 A JP2010510771 A JP 2010510771A JP 2009537717 A JP2009537717 A JP 2009537717A JP 2009537717 A JP2009537717 A JP 2009537717A JP 2010510771 A JP2010510771 A JP 2010510771A
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protein
post
fret
compound
fluorescent
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Japanese (ja)
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JP2010510771A5 (enExample
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トランケ，エリック
ブリンカー，アヒム
クラレ，エマニュエル
マティ，ジェラール
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2009537717A 2006-11-27 2007-11-27 翻訳後修飾の検出のための方法 Pending JP2010510771A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86108506P 2006-11-27 2006-11-27
PCT/IB2007/004341 WO2008065540A2 (en) 2006-11-27 2007-11-27 Method for the detection of post-translational modifications

Publications (2)

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JP2010510771A true JP2010510771A (ja) 2010-04-08
JP2010510771A5 JP2010510771A5 (enExample) 2010-11-25

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JP2009537717A Pending JP2010510771A (ja) 2006-11-27 2007-11-27 翻訳後修飾の検出のための方法

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US (1) US8663928B2 (enExample)
EP (1) EP2087355B1 (enExample)
JP (1) JP2010510771A (enExample)
WO (1) WO2008065540A2 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011090159A1 (ja) * 2010-01-22 2011-07-28 独立行政法人科学技術振興機構 蛋白質の分解活性を測定するためのプローブ試薬
CN103630691B (zh) * 2012-08-24 2015-07-08 中国科学院深圳先进技术研究院 小泛素样修饰的生物检测方法
WO2014108480A1 (en) * 2013-01-09 2014-07-17 Friedrich-Alexander-Universitaet Erlangen-Nuernberg Method for in vitro detection and monitoring of a disease by measuring disease-associated protease activity in extracellular vesicles
CN104749143A (zh) * 2013-12-31 2015-07-01 深圳先进技术研究院 一种蛋白质类泛素化修饰的检测方法及其应用
KR101750407B1 (ko) 2014-11-10 2017-06-27 한양대학교 산학협력단 프로틴 카이네이즈 a 기질 인산화펩타이드에 결합하는 알엔에이 앱타머
CN107463795A (zh) * 2017-08-02 2017-12-12 南昌大学 一种识别酪氨酸翻译后修饰位点的预测算法
US11604186B2 (en) * 2018-10-17 2023-03-14 Molecular Devices (Austria) GmbH Real time western blot assays utilizing fluorescence resonance energy transfer (FRET)
WO2023091395A1 (en) * 2021-11-16 2023-05-25 Biogen Ma Inc. Method for detecting a lipidated protein via fluorescence resonance energy transfer (fret)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001036617A2 (en) * 1999-11-18 2001-05-25 Cyclacel Limited Assay for measuring enzyme activity in vivo
WO2005012329A2 (en) * 2003-07-29 2005-02-10 Invitrogen Corporation Kinase and phosphatase assays
WO2006044747A2 (en) * 2004-10-15 2006-04-27 Signal Pharmaceuticals, Llc P27 ubiquitination assay and methods of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6900304B2 (en) 1996-01-31 2005-05-31 The Regents Of The University Of California Emission ratiometric indicators of phosphorylation
GB9901072D0 (en) * 1999-01-19 1999-03-10 Imp Cancer Res Tech Methods for detecting changes to a macromolecular component of a cell
JP2004537047A (ja) * 2001-06-14 2004-12-09 アナディーズ　ファーマスーティカルズ，アイエヌシー． 標的分子のリガンドをスクリーニングする方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001036617A2 (en) * 1999-11-18 2001-05-25 Cyclacel Limited Assay for measuring enzyme activity in vivo
WO2005012329A2 (en) * 2003-07-29 2005-02-10 Invitrogen Corporation Kinase and phosphatase assays
WO2006044747A2 (en) * 2004-10-15 2006-04-27 Signal Pharmaceuticals, Llc P27 ubiquitination assay and methods of use

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JPN6013003036; Ｍｅｔｈｏｄｓ，　２００６，　Ｖｏｌ．４０，　ｐｐ．２７９-２８６ *

Also Published As

Publication number Publication date
US20100086943A1 (en) 2010-04-08
EP2087355A2 (en) 2009-08-12
EP2087355B1 (en) 2014-09-24
WO2008065540A3 (en) 2008-10-23
WO2008065540A2 (en) 2008-06-05
US8663928B2 (en) 2014-03-04

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