JP2010509937A - プロテインａ選択性を有する抗体 - Google Patents

プロテインａ選択性を有する抗体 Download PDF

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Publication number
JP2010509937A
JP2010509937A JP2009538451A JP2009538451A JP2010509937A JP 2010509937 A JP2010509937 A JP 2010509937A JP 2009538451 A JP2009538451 A JP 2009538451A JP 2009538451 A JP2009538451 A JP 2009538451A JP 2010509937 A JP2010509937 A JP 2010509937A
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JP
Japan
Prior art keywords
antibody
antigen
cell line
monoclonal antibody
binding fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2009538451A
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English (en)
Japanese (ja)
Other versions
JP2010509937A5 (https=
Inventor
エー． マッチ，パトリック
エス． レイフ−ウェンナー，マーラ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Innovative Properties Co
Original Assignee
3M Innovative Properties Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of JP2010509937A publication Critical patent/JP2010509937A/ja
Publication of JP2010509937A5 publication Critical patent/JP2010509937A5/ja
Withdrawn legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2009538451A 2006-11-22 2007-11-15 プロテインａ選択性を有する抗体 Withdrawn JP2010509937A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/562,759 US7488807B2 (en) 2006-11-22 2006-11-22 Antibody with protein A selectivity
PCT/US2007/084736 WO2008140570A2 (en) 2006-11-22 2007-11-15 Antibody with protein a selectivity

Publications (2)

Publication Number Publication Date
JP2010509937A true JP2010509937A (ja) 2010-04-02
JP2010509937A5 JP2010509937A5 (https=) 2011-01-06

Family

ID=39417386

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009538451A Withdrawn JP2010509937A (ja) 2006-11-22 2007-11-15 プロテインａ選択性を有する抗体

Country Status (4)

Country Link
US (2) US7488807B2 (https=)
EP (1) EP2087003A2 (https=)
JP (1) JP2010509937A (https=)
WO (1) WO2008140570A2 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100062418A1 (en) * 2006-11-22 2010-03-11 Mach Patrick A Inactivated and dried biological preparations
JP2010510524A (ja) 2006-11-22 2010-04-02 スリーエム イノベイティブ プロパティズ カンパニー 試料を調製及び分析するシステム並びに方法
US20100209946A1 (en) * 2007-04-19 2010-08-19 Naiyong Jing Uses of water-dispersible silica nanoparticles for attaching biomolecules
US8597959B2 (en) * 2007-04-19 2013-12-03 3M Innovative Properties Company Methods of use of solid support material for binding biomolecules
EP2220500A4 (en) * 2007-11-20 2010-12-15 3M Innovative Properties Co METHOD FOR ANALYZING A BACTERIUM SAMPLE USING A POLYMER DETECTOR CONTAINING DIACETYLENE
HUE026855T2 (en) 2009-04-03 2016-07-28 Univ Chicago Compositions and methods related to protein a (spa) variants
CA2803298C (en) 2010-07-02 2020-07-14 The University Of Chicago Compositions and methods related to protein a (spa) variants
BR112014003315A2 (pt) 2011-08-15 2017-03-01 Univ Chicago composições e métodos relacionados a anticorpos para a proteína a estafilocócica
US9988439B2 (en) 2011-12-23 2018-06-05 Nicholas B. Lydon Immunoglobulins and variants directed against pathogenic microbes
WO2013096948A1 (en) 2011-12-23 2013-06-27 Lydon Nicholas B Immunoglobulins and variants directed against pathogenic microbes
WO2015187779A1 (en) 2014-06-03 2015-12-10 Xbiotech, Inc. Compositions and methods for treating and preventing staphylococcus aureus infections
CA3110377A1 (en) * 2018-11-21 2020-05-28 Regeneron Pharmaceuticals, Inc. Anti-staphylococcus antibodies and uses thereof
US12514914B2 (en) 2019-05-14 2026-01-06 The University Of Chicago Methods and compositions comprising Staphylococcus protein a (SpA) variants
CN114929750B (zh) 2019-09-13 2024-11-22 芝加哥大学 用于治疗葡萄球菌感染的方法和组合物

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4741900A (en) 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
GB8426463D0 (en) 1984-10-19 1984-11-28 Technology Licence Co Ltd Monoclonal antibodies
JPS63273495A (ja) 1987-04-30 1988-11-10 Sekisui Chem Co Ltd 抗プロテインａ単クロ−ン性抗体とその製法，および該抗体を用いるプロテインａの測定方法
EP0436597B1 (en) 1988-09-02 1997-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
DK0585287T3 (da) 1990-07-10 2000-04-17 Cambridge Antibody Tech Fremgangsmåde til fremstilling af specifikke bindingsparelementer
CA2095633C (en) 1990-12-03 2003-02-04 Lisa J. Garrard Enrichment method for variant proteins with altered binding properties
EP1820858B1 (en) 1991-03-01 2009-08-12 Dyax Corporation Chimeric protein comprising micro-protein having two or more disulfide bonds and embodiments thereof
ATE414768T1 (de) 1991-04-10 2008-12-15 Scripps Research Inst Bibliotheken heterodimerer rezeptoren mittels phagemiden
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
US6994855B1 (en) 1994-08-22 2006-02-07 The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin S. aureus fibrinogen binding protein gene
US6008341A (en) 1994-08-22 1999-12-28 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin S. aureus fibrinogen binding protein gene
US5594116A (en) 1995-11-08 1997-01-14 Promega Corporation Tryptase polyclonal antibody and purification method for use in human tryptase immunoassay
FR2746398B1 (fr) 1996-03-21 1998-04-30 Bio Merieux Anticorps specifique de staphylococcus aureaus, et utilisations
MXPA03011701A (es) 2001-06-15 2004-12-06 Nhibitex Inc Anticuerpos monoclonales y policlonales de reaccion que reconocen las proteinas de superficie a partir de estafilococos coagulasa-negativos y staphylococcus aureus.
ES2322945T5 (es) 2001-12-21 2012-10-17 Immunex Corporation Métodos para purficación de proteína
EP1580557A4 (en) * 2002-11-22 2006-09-06 Daiichi Pure Chemicals Co Ltd METHOD FOR THE STUDY OF STAPHYLOCOCCUS AUREUS
US20100317021A1 (en) * 2006-11-22 2010-12-16 Vinod P. Menon Fluidic antibody-containing devices and methods

Also Published As

Publication number Publication date
WO2008140570A2 (en) 2008-11-20
US20080118937A1 (en) 2008-05-22
US7488807B2 (en) 2009-02-10
US20090162902A1 (en) 2009-06-25
WO2008140570A3 (en) 2009-03-05
EP2087003A2 (en) 2009-08-12

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