JP2010509937A - プロテインａ選択性を有する抗体 - Google Patents

プロテインａ選択性を有する抗体 Download PDF

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Publication number
JP2010509937A
JP2010509937A JP2009538451A JP2009538451A JP2010509937A JP 2010509937 A JP2010509937 A JP 2010509937A JP 2009538451 A JP2009538451 A JP 2009538451A JP 2009538451 A JP2009538451 A JP 2009538451A JP 2010509937 A JP2010509937 A JP 2010509937A
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JP
Japan
Prior art keywords
antibody
antigen
cell line
monoclonal antibody
binding fragment
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JP2009538451A
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English (en)
Japanese (ja)
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JP2010509937A5 (https=
Inventor
エー． マッチ，パトリック
エス． レイフ−ウェンナー，マーラ
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3M Innovative Properties Co
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3M Innovative Properties Co
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Application filed by 3M Innovative Properties Co filed Critical 3M Innovative Properties Co
Publication of JP2010509937A publication Critical patent/JP2010509937A/ja
Publication of JP2010509937A5 publication Critical patent/JP2010509937A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1271—Micrococcaceae (F); Staphylococcaceae (F), e.g. Staphylococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2009538451A 2006-11-22 2007-11-15 プロテインａ選択性を有する抗体 Withdrawn JP2010509937A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/562,759 US7488807B2 (en) 2006-11-22 2006-11-22 Antibody with protein A selectivity
PCT/US2007/084736 WO2008140570A2 (en) 2006-11-22 2007-11-15 Antibody with protein a selectivity

Publications (2)

Publication Number Publication Date
JP2010509937A true JP2010509937A (ja) 2010-04-02
JP2010509937A5 JP2010509937A5 (https=) 2011-01-06

Family

ID=39417386

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2009538451A Withdrawn JP2010509937A (ja) 2006-11-22 2007-11-15 プロテインａ選択性を有する抗体

Country Status (4)

Country Link
US (2) US7488807B2 (https=)
EP (1) EP2087003A2 (https=)
JP (1) JP2010509937A (https=)
WO (1) WO2008140570A2 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20100062418A1 (en) * 2006-11-22 2010-03-11 Mach Patrick A Inactivated and dried biological preparations
US20100099115A1 (en) 2006-11-22 2010-04-22 Mach Patrick A Systems and methods for preparing and analyzing samples
EP2137533A2 (en) * 2007-04-19 2009-12-30 3M Innovative Properties Company Uses of water-dispersible silica nanoparticles for attaching biomolecules
WO2008131063A1 (en) * 2007-04-19 2008-10-30 3M Innovative Properties Company Methods of use of solid support material for binding biomolecules
CN101918842A (zh) * 2007-11-20 2010-12-15 3M创新有限公司 利用含二乙炔的聚合物传感器分析细菌样品的方法
ES2784957T3 (es) 2009-04-03 2020-10-02 Univ Chicago Composiciones y métodos relacionados con variantes de la proteína A (SPA)
JP6002128B2 (ja) 2010-07-02 2016-10-05 ザ・ユニバーシティ・オブ・シカゴＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃｈｉｃａｇｏ プロテインＡ（ＳｐＡ）変種に関連する組成物および方法
BR112014003315A2 (pt) 2011-08-15 2017-03-01 Univ Chicago composições e métodos relacionados a anticorpos para a proteína a estafilocócica
US9988439B2 (en) 2011-12-23 2018-06-05 Nicholas B. Lydon Immunoglobulins and variants directed against pathogenic microbes
WO2013096948A1 (en) 2011-12-23 2013-06-27 Lydon Nicholas B Immunoglobulins and variants directed against pathogenic microbes
KR101753553B1 (ko) 2014-06-03 2017-07-03 엑스바이오테크, 인크. 스타필로코커스 아우레우스 감염의 치료 및 예방을 위한 조성물 및 방법
BR112021005522A2 (pt) * 2018-11-21 2021-06-29 Regeneron Pharmaceuticals, Inc. anticorpo isolado ou fragmento de ligação ao antígeno do mesmo, composição farmacêutica, molécula polinucleotídica isolada, vetor, célula, e, métodos de prevenção, tratamento ou melhoria de infecção por s. aureus, uma condição causada por infecção por s. aureus, ou pelo menos um sintoma de infecção por s. aureus, ou de diminuir a frequência ou gravidade de infecção por s. aureus, uma condição causada por infecção por s. aureus, de pelo menos um sintoma de infecção por s. aureus, para prevenir uma infecção por s. aureus, de prevenção, tratamento ou melhoria de infecção por s. aureus, ou de diminuir a frequência ou gravidade de infecção por s. aureus, em um indivíduo com um cateter, uma articulação protética ou qualquer outro objeto estranho, para prevenir, tratar ou melhorar a infecção estafilocócica, ou para diminuir a frequência ou gravidade da infecção estafilócica
MX2021013833A (es) 2019-05-14 2022-03-17 Univ Chicago Metodos y composiciones que comprenden variantes de la proteina a de estafilococos (spa).
WO2021051136A1 (en) 2019-09-13 2021-03-18 The University Of Chicago Methods and compositions for treating staphylococcal infections

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4741900A (en) 1982-11-16 1988-05-03 Cytogen Corporation Antibody-metal ion complexes
GB8426463D0 (en) 1984-10-19 1984-11-28 Technology Licence Co Ltd Monoclonal antibodies
JPS63273495A (ja) 1987-04-30 1988-11-10 Sekisui Chem Co Ltd 抗プロテインａ単クロ−ン性抗体とその製法，および該抗体を用いるプロテインａの測定方法
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
EP0436597B1 (en) 1988-09-02 1997-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
EP0585287B1 (en) 1990-07-10 1999-10-13 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
CA2405246A1 (en) 1990-12-03 1992-06-11 Genentech, Inc. Enrichment method for variant proteins with alterred binding properties
EP0575485A1 (en) 1991-03-01 1993-12-29 Dyax Corp. Process for the development of binding mini-proteins
DK0580737T3 (da) 1991-04-10 2004-11-01 Scripps Research Inst Heterodimere receptorbiblioteker ved anvendelse af phagemider
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
US6994855B1 (en) 1994-08-22 2006-02-07 The Provost Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin S. aureus fibrinogen binding protein gene
US6008341A (en) 1994-08-22 1999-12-28 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth Near Dublin S. aureus fibrinogen binding protein gene
US5594116A (en) 1995-11-08 1997-01-14 Promega Corporation Tryptase polyclonal antibody and purification method for use in human tryptase immunoassay
FR2746398B1 (fr) 1996-03-21 1998-04-30 Bio Merieux Anticorps specifique de staphylococcus aureaus, et utilisations
JP4424984B2 (ja) 2001-06-15 2010-03-03 インヒビテックス インコーポレーテッド コアグラーゼ陰性ブドウ球菌および黄色ブドウ球菌由来の表面蛋白質を認識する、交差反応性モノクローナルおよびポリクローナル抗体
WO2003059935A2 (en) 2001-12-21 2003-07-24 Immunex Corporation Methods for purifying protein
AU2003284643A1 (en) 2002-11-22 2004-06-18 Daiichi Pure Chemicals Co., Ltd. Method of examining staphylococcus aureus
WO2008064232A2 (en) * 2006-11-22 2008-05-29 3M Innovative Properties Company Fluidic antibody-containing devices and methods

Also Published As

Publication number Publication date
US7488807B2 (en) 2009-02-10
US20090162902A1 (en) 2009-06-25
US20080118937A1 (en) 2008-05-22
EP2087003A2 (en) 2009-08-12
WO2008140570A3 (en) 2009-03-05
WO2008140570A2 (en) 2008-11-20

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