JP2010264068A - Animal fixing device - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an animal fixing device capable of simply fixing the head of an animal in a short time without injuring the animal. <P>SOLUTION: The animal fixing device 1 for fixing the head of an animal includes a case part 2 having an opening 2a at one end thereof, a foretooth locking part 3a fixed at the optional position in the case part 2 and locked with the foretooth of the animal to fix the foretooth, a head fixing part 4 capable of housing the foretooth locking part 3a, having a nostril cover part 4c, which is formed so as to have predetermined volume not closing the nasal cavity and oral cavity of the animal and has the contact part 4d coming into contact with a part of the head, on the side of the opening 2a and provided so as to be reciprocally moved through the case part 2, and a pressure applying part 5 for applying pressure to the head fixing part 4 in the direction of the opening 2a so as to allow the head fixing part 4 to approach the opening 2a. <P>COPYRIGHT: (C)2011,JPO&amp;INPIT

Description

  The present invention relates to an animal fixture for fixing an animal head in an inspection or the like.

  Magnetic Resonance Imaging (referred to as Magnetic Resonance Imaging (MRI)), Positron Emission Tomography (referred to as (Positron Emission Tomography) PET), Single Photon Emission Computed Tomography ((Single Photon Emission Computed Tomography) ) It is called SPECT.) When taking an image of the inside of a living body of an animal by X-ray computed tomography (called X-ray computed tomography), a clear image cannot be obtained. So it is necessary to fix the animal. Conventionally, three-point fixation for fixing both ears and teeth has been generally used for animal head fixation. For convenience of explanation, photographing with these photographing methods is referred to as MRI photographing or the like.

For example, Patent Literature 1 is disclosed as such an animal fixture. The animal fixture described in Patent Document 1 is shown in FIG. The animal fixing tool described in Patent Document 1 includes first fixing members w1 and w2 for fixing both ears of an animal, a second fixing member w3 for fixing the front teeth of the animal, and the first fixing member. and a base w4 that supports w1, w2 and the second fixing member w3.
The first fixing members w1 and w2 include insertion pins e1 and e2 that are inserted into both ear holes of the animal, and screws n1 and n2 that press and fix the insertion pins e1 and e2. Since the insertion pin is released by loosening the screws n1 and n2, the amount of projection into the ear hole can be adjusted.
The second fixing member w3 includes a hook pin h for hooking the front teeth of the animal, screws n3 and n4 for adjusting the vertical position of the hook pin h, a screw n5 for adjusting the front and rear position of the second fixing member w3, An anesthetic gas injection cylinder m for injecting a gas for making the anesthetic state.

  Next, with reference to FIG. 13, the fixing operation by the animal fixture described in Patent Document 1 will be described. First, after placing the animal at a predetermined position on the base w4, an anesthetic gas is injected from the anesthetic gas injection cylinder m. Next, the insertion pins e1 and e2 are inserted into each ear hole of the animal in a state where the screws n1 and n2 included in the first fixing members w1 and w2 are loosened. In this state, the screws n1 and n2 are tightened to fix the insertion pins e1 and e2. Next, after loosening the screw n5 included in the second fixing member w3 and adjusting the position of the second fixing member w3 in the front-rear direction to determine the front-rear position of the hook pin h, the screw n5 is tightened to tighten the second fixing member w3. To fix. Next, after the screws n3 and n4 included in the second fixing member w3 are rotated to adjust the vertical position of the hook pin h, the animal's front teeth are hooked on the hook pin h to complete the fixing operation. The animal head is fixed by hooking the animal's front teeth with the hook pin h and inserting the insertion pins e1 and e2 into the ear holes.

Japanese Patent Laid-Open No. 2001-252292 (paragraphs 0023 to 0040, FIG. 2)

As described above, it is usual to fix the animal's head at three points, both ears and teeth, for MRI imaging, etc., but the screws for fixing the pins after the pins are inserted into the ear holes The tightening operation is necessary and the work is troublesome. Therefore, development of an animal fixture that can easily fix the head of the animal is desired.
Further, in recent MRI imaging of experimental animals, it is not uncommon to image a plurality of animals at once, and it is strongly desired to shorten the time for fixing the animals.

  Furthermore, in the conventional three-point fixation of both ears and teeth, the pin must be inserted deep into the animal's ear hole when trying to fix firmly with both ears. Since the pin is inserted into the ear hole of the animal only by human sense, it is difficult to know how far it can be inserted, and if the pin is inserted too much, the animal will be damaged. Conversely, if the pin is inserted too shallow, it will not be fixed well. As described above, the conventional three-point fixation of both ears and teeth requires a certain skill in the fixing operation. Therefore, development of an animal fixture that is easy to operate without damaging the animal is desired.

  The present invention has been made in view of the above problems, and provides an animal fixture that can easily fix an animal's head in a short time and can fix an animal without damaging it. Let it be an issue.

  An animal fixing tool according to the present invention is an animal fixing tool for fixing the head of an animal, the case having an opening at one end, and fixed at an arbitrary position in the case, and the front teeth of the animal A front tooth latching portion that latches and fixes the front tooth latching portion, and is formed with a predetermined volume so as not to block the nasal cavity and oral cavity of the animal, and a part of the head A nose mouth cover portion having an abutting portion that abuts is provided on the opening portion side, and a head fixing portion provided in a reciprocating manner within the case portion, and the head fixing portion are close to the opening portion. And a pressure applying portion that applies pressure in the direction of the opening, and the contact portion of the head fixing portion latches the front teeth on the front tooth retaining portion by the pressure of the pressure applying portion. The animal is pressed and fixed in the direction of the opening.

  Thus, the animal fixture according to the present invention is such that the front teeth of the animal are hooked on the front tooth catching portion, and the pressure applying portion applies pressure in the direction of the opening of the case portion to the head fixing portion. Thus, the head of the animal can be pressed and fixed in the direction of the opening at the contact portion of the head fixing portion.

  In addition, the animal fixture according to the present invention is characterized in that the case portion is formed in a bottomed cylindrical shape, or two or more support members are arranged in parallel.

  As described above, the animal fixing tool according to the present invention is a head fixing portion in which the front teeth of the animal are hooked on the front tooth locking portion, and pressure is applied so as to be close to the opening of the case portion by the pressure applying portion. The abutment part of the nostril cover part can fix the animal head simply by abutting a part of the animal head.

In the animal fixture according to the present invention, when the case portion is the bottomed cylindrical case portion, the pressure applying portion is a pressurizing device that applies pressure to an elastic body or a medium. Features.
Further, in the animal fixture according to the present invention, when the case part is a case part in which the two or more support members are arranged in parallel, the pressure applying part is an elastic body. And
Thus, the animal fixture according to the present invention can fix an animal with an appropriate pressure.

Moreover, the animal fixture according to the present invention is characterized in that the front tooth latching portion is U-shaped, V-shaped, T-shaped or L-shaped.
As described above, the animal fixture according to the present invention can be formed by matching the shape of the front teeth latching portion with the shape of the front teeth of the animal. In addition, if the U-shape or V-shape is used, the animal's teeth can be positioned at a predetermined position, so that the animal's head can be fixed more accurately and stably.

Further, the animal fixture according to the present invention is an anesthesia gas supply port for supplying anesthesia gas to a position in the vicinity of the nasal cavity and the oral cavity of at least one of the front tooth latching part and the head fixing part. Is provided.
Thus, since the animal fixture according to the present invention is provided with an anesthetic gas supply port for supplying anesthetic gas to a position near the nasal cavity and oral cavity, the anesthetic gas can be reliably supplied to the animal. it can.

The animal fixture according to the present invention is characterized in that the head fixing portion is provided with a pressure sensor on a contact surface with the animal.
Thus, the animal fixture according to the present invention can measure the pressure on the contact surface between the animal and the head fixing portion by providing the pressure sensor.

The animal fixture according to the present invention is made of a nonmagnetic material.
As described above, if the animal fixture according to the present invention is made of a non-magnetic material, the selected material does not have magnetism, so that it can be suitably photographed by MRI imaging or the like. In addition, it is possible to manufacture an animal fixture that takes into consideration ease of processing, cost, recyclability, and disposableness.

  The animal fixture according to the present invention is an animal fixture for fixing the head of an animal, and is provided with a base portion having an animal insertion portion for inserting the animal at one end thereof, and reciprocating within the base portion. A front tooth latching portion that latches and fixes the front teeth of the animal, and a pressure applying portion that applies pressure in a direction away from the animal insertion portion so that the front tooth latching portion is away from the animal insertion portion. And the base is configured to have a predetermined volume so as to accommodate the front teeth latching portion and not to block the nasal cavity and oral cavity of the animal, and is in contact with a part of the head A nose mouth cover portion having a portion on the animal insertion portion side, and pulling the animal having the front teeth hooked on the front tooth catching portion in a direction away from the animal insertion portion by the pressure of the pressure applying portion. Then, it is suppressed and fixed to the contact portion of the nostril cover portion. Characterized in that it.

  As described above, the animal fixture according to the present invention applies pressure so that the animal having the front teeth hooked on the front tooth hooking portion is moved away from the animal insertion portion by the pressure applying portion, and the animal is separated from the animal insertion portion. By pulling in the direction, a part of the animal's head and the contact portion can be brought into contact with each other and suppressed and fixed.

Moreover, the animal fixture according to the present invention is characterized in that the front tooth latching portion is repressed by a restraining portion at a predetermined position and released from a state of being restrained at the predetermined position.
Thus, since the animal fixture which concerns on this invention is provided with the control part, it can fix | release a front-tooth latching part in a predetermined position, and can open | release from a fixed position.

  The present invention can easily fix the head of an animal in a short time. Furthermore, it does not hurt animals.

It is a perspective view including the partial cross section of the animal fixture which concerns on 1st Embodiment of this invention. It is a perspective view of the front tooth latching part with which the animal fixture concerning a 1st embodiment of the present invention is provided. It is a principal part longitudinal cross-sectional view which shows the fixing operation | movement of the animal fixture which concerns on 1st Embodiment of this invention. It is a principal part longitudinal cross-sectional view which shows the fixing operation | movement of the animal fixture which concerns on 1st Embodiment of this invention. It is a principal part longitudinal cross-sectional view which shows the fixing operation | movement of the animal fixture which concerns on 1st Embodiment of this invention. (A)-(g) is a perspective view which shows the modification of a front tooth latching part. It is a longitudinal cross-sectional view of the animal fixture which concerns on 2nd Embodiment of this invention. It is a longitudinal cross-sectional view of the animal fixture which concerns on 3rd Embodiment of this invention. It is a longitudinal cross-sectional view of the animal fixture which concerns on 4th Embodiment of this invention. It is a longitudinal cross-sectional view of the animal fixture which concerns on 5th Embodiment of this invention. It is a longitudinal cross-sectional view of the animal fixture which concerns on 6th Embodiment of this invention. It is a longitudinal cross-sectional view of the animal fixture (at the time of a stop) which concerns on 6th Embodiment of this invention. It is a top view of the animal fixture seen from the upper direction in a prior art.

(First embodiment)
The animal fixture according to the first embodiment will be described with reference to FIGS.
The animal fixture 1 according to the first embodiment shown in FIG. 1 is a head fixture for fixing a mouse 10 (see FIG. 2). In the present embodiment, the mouse 10 is targeted. However, the present invention is not limited to the mouse, and may be, for example, a rat, a monkey, a dog, a cat, or the like, and can be widely applied to animals other than the mouse.

An animal fixture 1 shown in FIG. 1 is fixed to a bottomed cylindrical case portion 2 having an opening 2 a at one end and an arbitrary position in the case portion 2, and hooks the front teeth of an animal (mouse) 10. The front tooth latching portion 3a to be fixed and the front tooth latching portion 3a can be accommodated and formed with a predetermined volume so as not to block the nasal cavity and oral cavity of the animal (mouse) 10, A head fixing part 4 having a nose mouth cover part 4c having a contact part 4d in contact with the opening part 2a and being reciprocally movable in the case part 2 (directions α1 and α2 in FIG. 1); A pressure application unit 5 that applies pressure to the unit fixing unit 4 in the direction of the opening 2a (α1 direction in FIG. 1) so as to be close to the opening 2a.
Moreover, the animal fixture 1 shown in FIG. 1 has a stopper 7 that prevents separation of the screw 6 that fixes the front tooth fixing portion 3 to the case portion 2 and the case portion 2 due to movement of the head fixing portion 4 in the α1 direction. And anesthetic gas supply means (anesthetic gas supply port 3e and anesthetic gas supply path 3f).

There is no restriction | limiting in the material of the animal fixture 1. FIG. That is, any material may be used as long as it is difficult to fix the head of the mouse 10 such as extremely low strength. For example, it may be a polymer material such as resin or rubber, wood, paper or metal.
However, if MRI imaging or the like is performed after the mouse 10 is fixed, it is preferable not to use magnetic metal. This is because the magnetic metal disturbs the photographed image, and thus disturbs normal photographing. Therefore, if the animal fixture 1 predicated on MRI imaging or the like is manufactured, polymer materials, wood, paper, and nonmagnetic metals that are nonmagnetic materials are suitable.

The case portion 2 has a bottomed cylindrical shape having an opening 2a at one end and a bottom surface portion 2b at the other end. In the present embodiment, the case portion 2 is cylindrical, but is not limited to this. For example, it may be a square tube having at least one corner. The opening 2a and the bottom 2b need not have the same shape. The size of the case portion 2 is determined by the size of the head of the animal 10. In addition, in this embodiment, although the case formed in the bottomed cylindrical shape was illustrated, as a case where two or more support members other than the bottomed cylindrical case are arranged in parallel with the front tooth fixing portion 3 Also good.
A stopper 2 c that restricts the movement of the head fixing portion 4 in the α2 direction is formed inside the case portion 2. Further, holes 2d and 2e for installing the front tooth fixing portion 3 and the stopper 7 are formed in the bottom surface portion 2b of the case portion 2, and the front tooth fixing portion 3 is formed on the peripheral surface near the bottom surface portion 2b. The hole 2f for installing the screw 6 for fixing the to the case portion 2 is formed.

  As shown in FIG. 2, the anterior tooth fixing part 3 has an anterior tooth latching part 3a having a projection part 3b in which a rectangular opening 3c is formed and an anesthetic gas supply port 3e, and an anterior tooth fixing part having an anesthetic gas supply path 3f. A member 3d is provided. The front teeth of the mouse 10 are hooked in the opening 3c formed in the protrusion 3b of the front tooth hook 3a. Anesthesia gas injected from the outside is discharged from the anesthetic gas supply port 3e through the anesthetic gas supply path 3f.

  Although the front tooth latching part 3a is made into the shape which forms the square opening part 3c in the projection part 3b, it is not limited to this. The shape of the front tooth latching portion 3a is only required to fix the teeth of the animal 10 at a predetermined position, and can be appropriately determined in consideration of the shape of the teeth of the animal 10 and the like. A modification of the front tooth latching portion 3a will be described later. Further, the position of the protrusion 3 b of the front tooth latching portion 3 a is set at a position slightly deviated from the center of the case portion 2 with respect to the diameter. The position of the protrusion 3b can be appropriately determined in consideration of the position of the front teeth of the animal 10 to be fixed, the position of the nasal cavity, and the anesthetic gas supply port 3e.

The anesthetic gas supply port 3 e is installed in the vicinity of the nasal cavity and oral cavity of the mouse 10 when the mouse 10 is fixed to the animal fixture 1. Therefore, the anesthetic gas can be reliably supplied to the mouse 10. The anesthetic gas is injected from the outside, and is discharged from the anesthetic gas supply port 3e through the anesthetic gas supply path 3f. Thereby, the mouse | mouth 10 can be made to sleep with an anesthetic gas. In the present embodiment, the anesthetic gas supply port 3e is provided in the front tooth latch portion 3a, but is not limited thereto. A modification of the anesthetic gas supply means will be described later.
An anesthetic gas recovery port (not shown) is installed at an arbitrary position in the nasal cavity cover portion 4c. The anesthetic gas may be recovered from the anesthetic gas recovery port through an anesthetic gas recovery path (not shown) installed along the front tooth fixing portion 3. The anesthetic gas recovery path uses a small diameter silicon tube or the like. Since the anesthetic gas is forcibly injected by a pump or the like, the anesthetic gas is automatically collected as long as the anesthetic gas supply port is installed. Therefore, it is not necessary to use a pump or the like to collect the anesthetic gas, and it is only necessary to provide a route.

  The front tooth fixing part 3 is fixed to the case part 2 by a screw 6 via a front tooth fixing member 3d provided in the front tooth fixing part 3. In the present embodiment, the front tooth fixing portion 3 has a rod shape, but is not limited thereto. A modification of the front tooth fixing portion 3 will be described later. The front tooth fixing portion 3 can be advanced and retracted in the α1 and α2 directions by loosening the screws 6, and the front tooth fixing portion 3 is fixed at an arbitrary position in the case portion 2 by tightening the screws 6. Therefore, the position of the front tooth latching portion 3a can be moved in the α1 or α2 direction within the case portion 2 in accordance with the size of the mouse 10 or the head shape.

  The head fixing portion 4 shown in FIG. 1 includes a pressure applied portion 4a that receives pressure from a pressure applying portion 5 (details will be described later), an inner hole 4b through which the front tooth latching portion 3a is inserted, and the front of the mouse 10 And a conical nose mouth cover part 4c having a shape along the part, and can reciprocate in the case part 2 in the directions α1 and α2. In the present embodiment, the nostril cover portion 4c has a substantially conical shape, but is not limited thereto. The shape of the nostril cover portion 4 c is determined according to the shape of the head of the animal 10. For example, it may be hemispherical or may have a corner shape. In the present embodiment, the shape of the nostril cover portion 4 c is substantially conical in accordance with the shape of the head of the mouse 10. In addition, the part which contacts the mouse | mouth 10 among the nostril cover parts 4c is called contact part 4d.

  The head fixing portion 4 is joined to the stopper 7. This prevents the head fixing portion 4 from moving in the α1 direction beyond the opening 2a of the case portion 2 when pressure is applied from the pressure applying portion 5 to the pressure applied portion 4a. As another means, for example, a configuration may be adopted in which a stopper is installed in the vicinity of the opening 2 a inside the case portion 2. Details will be described later.

  The pressure applying unit 5 illustrated in FIG. 1 applies pressure in the α1 direction to the head fixing unit 4. In the present embodiment, the pressure applying unit 5 uses a compression coil spring as an elastic body, but is not limited thereto. As long as it is an elastic body, it may be a spring other than the compression coil spring, rubber other than the spring, sponge, or the like. That is, the elastic body is not limited to the compression coil spring as long as a predetermined pressing force is obtained. The configuration of the pressure applying unit 5 can be appropriately selected in consideration of the strength of the pressure and the like. The configuration other than the compression coil spring used in the present embodiment will be described in detail in the second embodiment. Further, the pressure is intended to include a force by an elastic body, a pressure by a fluid, and the like.

  The pressure for fixing the mouse 10 by the compression coil spring is determined by the spring constant and the amount of deformation of the spring. The spring constant is determined by a combination of a spring material, a wire diameter, a coil effective diameter, and a coil effective winding number. Therefore, the material, the diameter of the wire, the effective diameter of the coil, the effective number of turns of the coil, and the deformation amount are selected according to the state of the mouse 10. For example, when the weight of the mouse 10 is heavy, a certain amount of pressure is required, and conversely, depending on the state of the mouse 10, there is a case where a pressure exceeding a certain level may not be applied. Determine the spring constant and amount of deformation of the spring.

(Fixing operation of the animal fixture according to the first embodiment)
Next, the fixing operation of the mouse 10 in the animal fixture 1 according to the first embodiment will be described with reference to FIGS. Although details of the fixing operation will be described later, in brief, there are two operations: an operation of hooking the front teeth of the mouse 10 on the front tooth holding portion 3a and an operation of fixing the head of the mouse 10 by the head fixing portion 4. Divided into two.

  The mouse 10 should be anesthetized in advance. When the anesthesia is effective for the mouse 10, the mouse 10 can be easily fixed by the animal fixture 1.

A method for hooking the front teeth of the mouse 10 to the front tooth hook 3a will be described.
As shown in FIG. 1, in the state where nothing is added, since the front tooth latching portion 3a is housed in the head fixing portion 4, in this state, the front teeth are latched on the front tooth latching portion 3a. I can't. Therefore, it is necessary to move the head fixing | fixed part 4 to (alpha) 2 direction and to take out the front-tooth latching | locking part 3a from the head fixing | fixed part 4 outside. Therefore, as shown in FIG. 3, the head fixing portion 4 is accommodated in the head fixing portion 4 by pushing the head fixing portion 4 by hand from the opening 2 a side and bringing the head fixing portion 4 close to the bottom portion 2 b of the case portion 2. The front tooth latching part 3a which has been made is taken out from the head fixing part 4. By the operation of pushing the head fixing portion 4, the front tooth latching portion 3 a can be latched.
Here, the state in which the head fixing portion 4 is brought close to the bottom surface portion 2b is a state in which an elastic force is stored due to the compression coil spring 5 in the case portion 2 being contracted and deformed. The front tooth of the mouse 10 is hooked on the front tooth hooking portion 3a while the compression coil spring 5 stores the elastic force. In this state, the head of the mouse 10 is not yet fixed.

Next, a method for fixing the head of the mouse 10 by the head fixing part 4 will be described.
While the front teeth of the mouse 10 are hooked on the front tooth hooking portion 3a, the hand is released from the head fixing portion 4 pressed by the hand. Then, as shown in FIG. 4, the head fixing | fixed part 4 is pushed back in the opening part 2a direction with the elastic force by the expansion deformation of the compression coil spring 5. As shown in FIG. Then, as shown in FIG. 5, a part of the head of the mouse 10 comes into contact with the contact part 4 d of the nostril cover part 4 c of the head fixing part 4.
In this state, the compression coil spring 5 is still contracted by the amount of contact between the mouse 10 and the head fixing portion 4, and the compression coil spring 5 applies the elastic force due to the contraction to the pressure applied portion of the head fixing portion 4. This is the state given to 4a. Then, the elastic force due to the contraction of the compression coil spring 5 becomes a force that pushes the head of the mouse 10 toward the opening 2 a of the case portion 2 via the head fixing portion 4. The mouse 10 does not move even if it is pushed toward the opening 2a by the head fixing part 4 because the front tooth is hooked on the front tooth latching part 3a, and the elastic force due to the contraction of the compression coil spring 5 is not generated. The pressure for fixing the mouse 10 is used as it is.
Thereby, the fixing operation of the mouse 10 in the animal fixture 1 according to the first embodiment is completed.

  In the state of FIG. 5, MRI imaging of the mouse 10 can be performed. Furthermore, during MRI imaging or the like, anesthetic gas may be injected from the outside into the anesthetic gas supply path 3f and discharged from the anesthetic gas supply port 3e through the anesthetic gas supply path 3f.

(Modification of the front tooth latching portion according to the first embodiment)
A modification of the front tooth latching portion 3a according to the first embodiment is shown in FIG.
FIG. 6A shows a front tooth latching portion 613a having a U-shaped projection 613b. FIG. 6B shows a front tooth latching portion 623a having a V-shaped projection 623b. The front teeth latching portions 613a and 623a are particularly suitable for fixing the teeth of rodent animals. That is, in the rodent animal, the front two upper teeth protrude from the center, so that the front teeth can be hooked on the U-shaped inner side of the tip of the protruding portion 613b and the V-shaped inner side of the tip of the protruding portion 623b. . Thereby, the front teeth can be positioned at a predetermined position without moving left and right. Therefore, the animal head can be fixed with high accuracy and stability.

  FIG. 6C shows a front tooth latching portion 633a having a T-shaped projection 633b. FIG. 6D shows a front tooth latching portion 643a having a substantially T-shaped protrusion 643b. FIG. 6E shows a front tooth latching portion 653a having an L-shaped projection 653b. FIG. 6F illustrates a front tooth latching portion 663a having a substantially L-shaped projection 663b. These front teeth latching portions 633a to 663a are particularly suitable for fixing teeth of animals such as monkeys, dogs and cats. That is, since animals such as monkeys, dogs, and cats have little protrusion of the central front teeth, it is difficult to hook the front teeth at the front teeth latching portions 613a and 623a. Therefore, by hooking the front tooth latching portions 633a to 663a behind the front upper teeth of the animal, the front teeth can be positioned at a predetermined position without moving left and right. Therefore, the animal head can be fixed with high accuracy and stability.

  FIG. 6G shows a front tooth latching portion 673a in which a thread-like member 673d having strength is connected to both ends of a T-shaped projection 673b. The front tooth latching portion 673a is particularly suitable for fixing primate teeth. The thread-like member 673d of the front tooth hooking portion 673a is hooked on at least one of the upper tooth and the lower tooth of the animal.

(Second Embodiment)
The animal fixture 701 of the second embodiment shown in FIG. 7 has a configuration in which the pressure applying unit 705 is realized by a pressurizing device (medium pressurizing device) 11 that applies pressure to the medium. The pressure applying unit 705 includes a pressure gauge (not shown), and the head fixing unit 704 includes a pressure sensor 13 for measuring the pressing force of the head fixing unit 704 on the mouse 10. Furthermore, the anesthetic gas supply means (anesthetic gas supply port 703e and anesthetic gas supply path 703f) is different from the first embodiment.

  Here, in the second embodiment, for convenience of explanation, other forms of each component in the first embodiment are described in the same embodiment, and the pressure applying unit 705, the pressure sensor 13, and the anesthesia in the second embodiment are described. The gas supply means (anesthetic gas supply port 703e and anesthetic gas supply path 703f) are not necessarily realized in the same embodiment. That is, instead of the anesthetic gas supply means of the second embodiment, the anesthetic gas supply means of the first embodiment may be used, or only the pressure sensor 13 may be provided in the first embodiment. In the description, parts having similar functions are denoted by the same reference numerals.

  The animal fixture 701 of the second embodiment includes a case portion 702 that forms an exterior, and a front tooth latching portion 703a having a projection 703b in which an opening 703c for latching the front teeth of the mouse 10 is formed, and a front tooth fixing member. An anterior tooth fixing unit 703 including 703d, a pressure applying unit 705 that applies pressure in the α1 direction, a medium pressurizing device 11 and a medium supply path 12 for supplying a medium to the pressure applying unit 705, and a pressure applying unit 705. A head fixing portion 704 that is movable in the α1 direction by receiving pressure on the pressure applied portion 704a, a pressure sensor 13 for measuring the pressing force of the head fixing portion 704 on the mouse 10, and a front tooth fixing portion 703 are provided. The screw 6 fixed to the case part 2, the stopper 7, and the anesthetic gas supply means (anesthetic gas supply port 703e and the anesthetic gas supply path 703f) are provided. The O-rings (O-rings) S1, S2, S3, and S4 prevent the medium inside the case 702 from leaking.

  The case portion 702 is the same as the first embodiment except that a hole for installing the medium supply path 12 is formed at a position close to the bottom surface portion 2b. The screw 6 and the stopper 7 are the same as those in the first embodiment.

  The anterior tooth fixing part 703 and the head fixing part 704 are the same as those in the first embodiment except that anesthetic gas supply means (anesthetic gas supply port 703e and anesthetic gas supply path 703f) are different. Moreover, the pressure sensor 13 is installed in the contact part 704d of the nostril cover part 704c with which the head fixing | fixed part 704 is provided.

  The pressure applying unit 705 is realized by supplying a medium by a pressurizing device (medium pressurizing device) 11 that applies pressure to the medium. As the medium, air, water, oil, or the like may be used. The medium is supplied by the medium pressurizing device 11 through the medium supply path 12. Thereby, the pressure in the pressure applying unit 705 increases, and a force is generated to push the pressure applied unit 704a of the head fixing unit 704 in the direction of the opening 2a in an attempt to release the increased pressure. When the pressure applying unit 705 has such a configuration, the head of the animal 10 can be fixed with an appropriate pressure by adjusting the amount of medium flowing into the pressure applying unit 705.

  In addition, it is good also as a structure which installs the container made from an elastic material in the pressure provision part 705, for example, a container like a balloon, and inject | pours a medium in it.

  The pressure sensor 13 is installed on the contact surface between the head fixing portion 704 and the animal. Specifically, it is installed in the contact part 704d provided in the nostril cover part 704c of the head fixing part 704. Thereby, the pressure in the contact surface of the head fixing | fixed part 704 and an animal can be measured. And by measuring the pressure actually applied to the head of the animal 10 by installing the pressure applying unit 705 constituted by the medium pressurizing device 11 and the pressure sensor 13 in the same embodiment, Accordingly, it is possible to adjust the inflow amount of the medium of the pressure applying unit 705. When the pressure sensor 13 reaches a predetermined value, the supply of the medium to the pressure applying unit 705 may be stopped. Thereby, the head of the animal 10 can be fixed with a more appropriate pressure.

  However, the installation of the pressure sensor 13 does not necessarily have to be configured in the same embodiment as the pressure applying unit 705 configured by the medium pressurizing device 11. You may provide the pressure sensor 13 in the nostril cover part 4c of the head fixing | fixed part 4 of the animal fixture 1 which concerns on 1st Embodiment shown in FIG. In that case, it installs in the same position as the nostril cover part 4c of the head fixing | fixed part 704 of the animal fixing tool 701 which concerns on 2nd Embodiment.

  The anesthetic gas supply means (anesthetic gas supply port 703e and anesthetic gas supply path 703f) shown in FIG. 7 is another form of the anesthetic gas supply means (anesthetic gas supply ports 3e and 3f) of the first embodiment shown in FIG. . As shown in FIG. 7, the anesthetic gas supply port 703e is installed at a substantially middle point between the nostril cover portion 704c and the inner hole 704b, and the anesthetic gas supply passage 703f is installed so as to pass through the head fixing portion 704. Good.

(Fixing operation of the animal fixture according to the second embodiment)
With reference to FIG. 7, the fixing operation of the animal fixture 701 according to the second embodiment will be described.
When the animal fixing tool 701 is not touched, the front tooth latching portion 703a is housed in the head fixing portion 704. Therefore, in this state, the front teeth can be latched on the front tooth latching portion 703a. Can not. Therefore, it is necessary to move the head fixing | fixed part 704 to (alpha) 2 direction and to take out the front tooth latching | locking part 703a from the head fixing | fixed part 704. FIG. Therefore, the medium in the pressure applying unit 705 is sucked by the medium pressurizing device 11. Then, the pressure in the pressure application part 705 falls, and the head fixing | fixed part 704 moves so that it may adjoin to the bottom face part 2b direction by the effect | action of the lowered pressure. As a result, the front teeth can be hooked to the front tooth hooking portion 703a. In this state, the front tooth of the mouse 10 is hooked on the front tooth hooking portion 703a, but the head of the mouse 10 is not yet fixed.
Next, the medium is supplied into the pressure applying unit 705 by the medium pressurizing device 11 while the front teeth are hooked. Then, the pressure in the pressure applying unit 705 increases, and the head fixing unit 704 moves so as to be close to the opening 2a by the action of the increased pressure. Then, a part of the head of the mouse 10 and the contact portion 704d of the nostril cover portion 704c included in the head fixing portion 704 come into contact.
Thereby, the fixing operation of the animal fixture 701 according to the second embodiment is completed.

(Third embodiment)
The animal fixture 801 of the third embodiment shown in FIG. 8 is different from the anterior tooth fixing part 3 in the first embodiment shown in FIG. 1 in the shape of the anterior tooth fixing part 803 shown in FIG. That is, the front tooth fixing part 803 of this embodiment is different from the first embodiment in that it is integrated with the case part 802. In the description, parts having similar functions are denoted by the same reference numerals.

  The animal fixture 801 according to the third embodiment includes an anterior case hooking portion 803a having a case portion 802 that forms an exterior and a protrusion 803b in which an opening 803c for hooking the front teeth of the mouse 10 is formed. A portion 803, a pressure applying unit 805 that applies pressure in the α1 direction, a head fixing unit 804 that is movable in the α1 direction by receiving the pressure of the pressure applying unit 805 in the pressure applied unit 804a, a stopper 7, and anesthesia Gas supply means (anesthetic gas supply port 803e and anesthetic gas supply path 803f).

  As for case part 802, front tooth fixing part 803 is formed in one. In addition, the case portion 802 includes a hole portion 2d for installing the front tooth fixing portion 3 on the bottom surface portion 2b of the case portion 2 shown in FIG. 1 and a hole for installing the screw 6 on the peripheral surface close to the bottom surface portion 2b. The point which the part 2f is not formed differs from the case part 2 of 1st Embodiment.

  A slit 804e is formed in the head fixing portion 804 so that the front tooth fixing portion 803 can be installed. The slit 804e is formed in consideration of the reciprocating movement of the head fixing portion 804. For example, as shown in FIG. 8, a notch is made in a direction parallel to the longitudinal direction of the case portion 802.

(Fixing operation of the animal fixture according to the third embodiment)
With reference to FIG. 8, the fixing operation of the animal fixture 801 according to the third embodiment will be described.
In the state where nothing is applied to the animal fixture 801, the front tooth latching portion 803a is housed in the head fixing portion 804. Therefore, in this state, the front tooth can be latched on the front tooth latching portion 803a. Can not. Therefore, it is necessary to move the head fixing portion 804 in the α2 direction so that the front tooth latching portion 803a is taken out from the head fixing portion 804. Therefore, the head fixing portion 804 is manually pressed from the opening 2a side, and the head fixing portion 804 is brought close to the bottom surface portion 2b of the case portion 802, thereby fixing the head fixing portion 803a in which the front tooth latching portion 803a is accommodated. The unit 804 is taken out. By pushing the head fixing portion 804, the front teeth can be hooked to the front tooth hooking portion 803a. In this state, the front teeth of the mouse 10 are hooked, but the head of the mouse 10 is not yet fixed.
Next, in the state where the front teeth of the mouse 10 are hooked on the front tooth hooking portion 803a, the hand is released from the head fixing portion 804 pressed by the hand. Then, the head fixing portion 804 is pushed back in the direction of the opening 2a by the elastic force due to the extension deformation of the compression coil spring 805. Then, a part of the head of the mouse 10 comes into contact with the contact portion 804d of the nostril cover portion 804c included in the head fixing portion 804.
Thereby, the fixing operation of the animal fixture 801 according to the third embodiment is completed.
The movement of the head fixing portion 804 in the α2 direction can be limited by the slit 804e. Accordingly, the stopper 802c may not be provided on the case portion 802.

(Fourth embodiment)
The animal fixture 901 according to the fourth embodiment shown in FIG. 9 is configured except that a stopper 907 is provided instead of the stopper 7 as compared with the animal fixture 1 of the first embodiment (see FIG. 1). Are the same. The stopper 907 prevents the head fixing portion 4 from moving in the α1 direction beyond the opening 2a of the case portion 2 when pressure is applied from the pressure applying portion 5 to the pressure applied portion 4a. In addition, about the site | part of the function similar to 1st Embodiment, the same code | symbol is attached | subjected and demonstrated.

The stopper 907 has a ring shape and is installed in the vicinity of the opening 2 a inside the case portion 2. The stopper 907 is only required to be bonded to a predetermined position of the case portion 2 and is bonded by, for example, an adhesive. However, the stopper 907 may not be ring-shaped.
Further, without using the stopper 7 or the stopper 907, the case portion 2 and the pressure applying portion 5 are the pressure applying portion 5a portion, and the pressure applying portion 5 and the head fixing portion 4 are the pressure applying portion 5b portion, and the adhesive. You may join by etc.

(Fixing operation of the animal fixture according to the fourth embodiment)
The animal fixing operation of the animal fixture 901 according to the fourth embodiment shown in FIG. 9 has the same outline as that of the animal fixture 1 according to the first embodiment shown in FIGS.

(Fifth embodiment)
The animal fixture 1001 according to the fifth embodiment will be described with reference to FIG. In addition, about the site | part of the function similar to 4th Embodiment, the same code | symbol is attached | subjected and demonstrated.
An animal fixture 1001 according to the fifth embodiment is provided with a base part 1002 having an animal insertion part 1002a at one end and a reciprocating motion within the base part 1002 (in directions α1 and α2 in FIG. 10), and an animal (mouse) 10 ( The front tooth latching portion 3a for latching and fixing the front teeth of FIG. 3) and the front tooth latching portion 3a in a direction away from the animal insertion portion 1002 so as to be away from the animal insertion portion 1002a (see FIG. 10). (α2 direction) has a pressure applying portion 5 for applying pressure, and the base portion 1002 can accommodate the front tooth catching portion 3a and has a predetermined volume so as not to block the nasal cavity and oral cavity of the animal (mouse) 10. The nostril cover portion 4c having the contact portion 4d that contacts a part of the head is provided on the animal insertion portion 1002a side.

The base portion 1002 has a cylindrical shape having an animal insertion portion 1002a at one end and a concave pressing portion installation portion 1002b at the other end, but is not limited thereto. The base 1002 may be created from one member, or may be created by combining a plurality of members.
The base portion 1002 has, on the animal insertion portion 1002a side, an inner hole 4b through which the front tooth catching portion 3a is inserted, and a substantially conical nose mouth cover portion 4c having a shape along the frontal portion of the mouse 10.
In addition, the shape of the nose mouth cover part 4c is the same as the nose mouth cover part 4c of 1st Embodiment.

The anterior tooth fixing part 3 includes an anterior tooth locking part 3a having a projection 3b in which a rectangular opening 3c is formed and an anesthetic gas supply port 3e, and an anterior tooth fixing member 3d having an anesthetic gas supply path 3f.
Further, the front tooth fixing member 3d includes a pressure applied portion 1003g that receives pressure from the pressure applying portion 5 and a pressing portion 1003h that is pushed in the α1 direction by the operator during the fixing operation.
In addition, it is the same as that of 1st Embodiment that the shape of the front tooth latch part 3a is not limited to what is shown in FIG.

  The pressure application unit 5 applies pressure in the α2 direction to the front tooth fixing unit 3. In the present embodiment, the pressure applying unit 5 uses a compression coil spring as an elastic body. However, the present invention is not limited to this, as in the first embodiment.

(Fixing operation of the animal fixture according to the fifth embodiment)
Next, the fixing operation of the mouse 10 (see FIG. 3) in the animal fixture 1001 according to the fifth embodiment will be described with reference to FIG. Note that the animal fixture 1001 shown in FIG. 10 is a state in which the front teeth of the mouse 10 can be hooked.
When no operation is performed on the animal fixture 1001, the front tooth latching portion 3a is housed in the base 1002, so that the front tooth cannot be latched on the front tooth latching portion 3a in this state (not shown). ) Therefore, it is necessary to move the front tooth fixing portion 3 in the α1 direction so that the front tooth latching portion 3a is taken out from the base portion 1002. Therefore, the pressing portion 1003h is pushed by hand in the α1 direction to bring the front tooth latching portion 3a close to the animal insertion portion 1002a, thereby removing the front tooth latching portion 3a from the base 1002 in which it is housed. By pushing the front tooth fixing part 3, it becomes possible to hook the front tooth to the front tooth hooking part 3a (the state shown in FIG. 10). In this state, the front teeth of the mouse 10 are hooked, but the head of the mouse 10 is not yet fixed.
Next, in the state where the front teeth of the mouse 10 are hooked on the front tooth hooking portion 3a, the hand is released from the pressing portion 1003h pressed by the hand. Then, the front tooth fixing portion 3 is moved in the α2 direction by the elastic force due to the extension deformation of the compression coil spring 5, and the mouse 10 that is hooked on the front tooth hooking portion 3a is pulled in the α2 direction. Then, the mouse 10 is drawn into the nostril cover portion 4c of the base portion 1002, and a part of the head of the mouse 10 and the abutting portion 4d abut against each other and are suppressed.
Thereby, the fixing operation of the animal fixture 1001 according to the fifth embodiment is completed.

(Application example of fifth embodiment)
An animal fixture 1101 according to an application example of the fifth embodiment will be described with reference to FIG. In addition, about the site | part of the function similar to 5th Embodiment, the same code | symbol is attached | subjected and demonstrated.
The animal fixture 1101 according to the application example of the fifth embodiment is different from the animal fixture 1001 (see FIG. 10) of the fifth embodiment in that the base portion 1002, the pressure applied portion 1003g, and the front tooth fixing portion 3 The configuration is the same except that a stop portion 1109 (1109a, 1109b) is provided in between.

  The restraining part 1109 fixes the front tooth fixing part 3 to the elastic force of the pressure applying part 5 after the front tooth fixing part 3 moves in the α1 direction and reaches the position where the front tooth of the animal (mouse) 10 can be hooked. Against the movement in the α2 direction. In the present embodiment, the restraining portion 1109 includes a movable portion 1109 a that is fixed to the front tooth fixing portion 3 and a fixing portion 1109 b that is fixed to the base portion 1002. The restraining portion 1109 in the present embodiment is a heart cam mechanism (an apparatus that realizes a ballpoint pen knock mechanism), but is not limited thereto. That is, it is only necessary that the operation of the front tooth fixing portion 3 can be stopped. For example, a member penetrating inside may be installed on the side surface of the base portion 1002, and this member may be projected into the base portion 1002 by pressing from the outside, or the pressing portion installing portion 1002b of the base portion 1002 After the lid is installed and the front tooth fixing portion 3 is moved in the α1 direction, the front tooth fixing portion may be confined in the base portion 1002 by a closing operation.

(Fixing operation of animal fixture according to application example of fifth embodiment)
Next, the fixing operation of the mouse 10 (see FIG. 3) in the animal fixture 1101 according to the application example of the fifth embodiment will be described with reference to FIGS.
As shown in FIG. 11, when nothing is applied to the animal fixture 1101, the front tooth latching portion 3a is housed in the base 1002, and in this state, the front teeth are latched to the front tooth latching portion 3a. Can not do it. Therefore, it is necessary to move the front tooth fixing portion 3 in the α1 direction so that the front tooth latching portion 3a is taken out from the base portion 1002. Therefore, the pressing portion 1003h is pushed by hand in the α1 direction to bring the front tooth latching portion 3a close to the animal insertion portion 1002a, thereby removing the front tooth latching portion 3a from the base 1002 in which it is housed. By pushing the front tooth fixing part 3, it becomes possible to hook the front tooth to the front tooth hooking part 3a. Here, when the front tooth fixing portion 3 moves a predetermined distance, the front tooth fixing portion 3 is fixed at a predetermined position by the heart cam mechanism 1109 (state shown in FIG. 12). In this state, the front teeth of the mouse 10 are hooked, but the head of the mouse 10 is not yet fixed.
Next, while the front teeth of the mouse 10 are hooked on the front tooth hooking portion 3a, the pressing portion 1003h is pushed again in the α1 direction by hand to release the fixed state of the heart cam mechanism 1109. Then, the front tooth fixing portion 3 is moved in the α2 direction by the elastic force due to the extension deformation of the compression coil spring 5, and the mouse 10 that is hooked on the front tooth hooking portion 3a is pulled in the α2 direction. Then, the mouse 10 is drawn into the nostril cover portion 4c of the base portion 1002, and a part of the head of the mouse 10 and the abutting portion 4d abut against each other and are suppressed.
Thereby, the fixing operation of the animal fixture 1101 according to the application of the fifth embodiment is completed.

1,701,801 Animal fixture 2,702,802 Case part (guide part)
2a Opening part 2b Bottom face part 3a, 703a, 803a Front tooth latching part 613a, 623a, 633a, 643a, 653a, 663a Front tooth latching part 3e, 703e, 803e Anesthetic gas supply port 4, 704, 804 Head fixing part 4c, 704c, 804c Nostril cover part 4d, 704d, 804d Contact part 5, 705, 805 Pressure application part 10 Mouse (animal)
DESCRIPTION OF SYMBOLS 11 Medium pressurization apparatus 12 Medium supply path 13 Pressure sensor 1002 Base part 1002a Animal insertion part 1109 Stop part

Claims (10)

An animal fixture for fixing the animal head,
A case portion having an opening at one end;
An anterior locking part that is fixed at an arbitrary position in the case part and holds and fixes the front teeth of the animal;
A nose mouth cover portion that can accommodate the front tooth latching portion and has a predetermined volume so as not to block the nasal cavity and oral cavity of the animal, and has a contact portion that comes into contact with a part of the head; A head fixing portion provided on the opening side and provided so as to reciprocate within the case portion; and
A pressure applying part that applies pressure in the direction of the opening so that the head fixing part is close to the opening;
The abutment portion of the head fixing portion presses and fixes the animal having the front teeth hooked on the front teeth hooking portion in the direction of the opening by the pressure of the pressure applying portion. Animal fixture.   The animal fixture according to claim 1, wherein the case part is formed in a bottomed cylindrical shape, or two or more support members are arranged in parallel. When the case portion is the bottomed cylindrical case portion,
The animal fixture according to claim 2, wherein the pressure applying unit is a pressurizing device that applies pressure to an elastic body or a medium. When the case part is a case part in which the two or more support members are arranged in parallel,
The animal fixture according to claim 2, wherein the pressure applying part is an elastic body.   The animal fixture according to any one of claims 1 to 4, wherein the front tooth latching portion is U-shaped, V-shaped, T-shaped or L-shaped.   2. An anesthetic gas supply port for supplying anesthetic gas is provided at a position in the vicinity of the nasal cavity and the oral cavity of at least one of the front tooth latching portion and the head fixing portion. The animal fixture of any one of 1-5.   The animal head fixture according to any one of claims 1 to 6, wherein the head fixing portion is provided with a pressure sensor on a contact surface with the animal.   The animal fixture according to any one of claims 1 to 7, wherein the animal fixture is made of a nonmagnetic material. An animal fixture for fixing the animal head,
A base having an animal insertion part for inserting the animal at one end;
An anterior hooking portion that is reciprocally movable in the base, and hooks and fixes the front teeth of the animal;
A pressure applying portion that applies pressure in a direction away from the animal insertion portion so that the front tooth latching portion moves away from the animal insertion portion;
The base portion can accommodate the front tooth latching portion and is formed with a predetermined volume so as not to block the nasal cavity and the oral cavity of the animal, and has a contact portion that contacts a part of the head. A cover part is provided on the animal insertion part side,
By pulling the animal with the front teeth hooked on the front tooth hooking portion in a direction away from the animal insertion portion by the pressure of the pressure applying portion, the animal is suppressed to the contact portion of the nostril cover portion. Animal fixture characterized by fixing.   The animal fixing tool according to claim 9, wherein the front tooth latching portion is reciprocated by a restraining portion at a predetermined position and released from a state of being restrained at the predetermined position.

Images