JP2010252922A - Catheter - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a catheter capable of easily and quickly changing the distribution of the administration amount of a medicine or the like. <P>SOLUTION: The catheter includes: an elongated tubular outer cylinder 2 having an internal space 4 and at least one side face hole 5 passing through between the internal space 4 and the outside; an internal moving member 7 movably disposed in the state of attaching a side face to the inner surface of the internal space 4 and forming a flow path 14 communicating at least one side face opening part 15 provided on a part of the side face and the proximal end side; and a moving operation member 8 for performing the moving operation of the internal moving member 7 within the internal space 4. By the movement of the internal moving member 7 within the internal space 4, the superposition state of the side face hole 5 and at least one side face opening 15 is changed and the medicine administration distribution is changed. <P>COPYRIGHT: (C)2011,JPO&INPIT

Description

  The present invention relates to a catheter having at least a distal end portion inserted into a living body and having an opening on a side surface.

  Conventionally, a medicine or the like may be administered to a living tissue using a catheter having an opening on a side surface. In this case, the distribution of doses of drugs and the like in the living tissue is affected by the position, size, and number of openings.

Special table 2003-504132 gazette

  By the way, the site | part which needs administration of the chemical | medical agent etc. in a biological tissue may change gradually with the administration result of a chemical | medical agent etc., or the change of a symptom. For example, if a drug is administered and the tumor size becomes smaller and the drug administration range becomes narrower, or if there is a lesion that has not penetrated the drug, it is necessary to administer the drug to this lesion. As a result, the drug administration range may be expanded.

  On the other hand, when the opening for drug administration is small, drug clogging may occur. In this case, it is desirable to increase the dose of the drug or the like from the opening adjacent to the opening clogged with the drug.

  However, even if a situation arises in which the distribution of the dosage of the above-mentioned medicine or the like is desired after the catheter is installed, conventionally, a surgery for exchanging or moving the catheter is required, and it is difficult to take a simple and quick countermeasure. Met.

  The present invention has been made in view of the above, and an object of the present invention is to provide a catheter capable of changing the dose distribution of a drug or the like simply and quickly.

  In order to solve the above-mentioned problems and achieve the object, a catheter according to the present invention has an elongated tubular outer cylinder having an internal channel and at least one side hole penetrating between the internal channel and the outside. And an internal movement in which a flow path is formed that is movably disposed in a state in which the side surface is in close contact with the inner surface of the internal channel, and that communicates at least one side surface opening portion provided at a part of the side surface with the base end side. And a movement operation member that performs a movement operation of the internal movement member in the internal channel, and the side hole and the at least one side surface opening portion by movement of the internal movement member in the internal channel The superposition state is changed.

  In the catheter according to the present invention as set forth in the invention described above, the internal movement member is formed with a communication flow path for communicating the distal end side and the proximal end side.

  The catheter according to the present invention is characterized in that, in the above invention, the movement operation member and the internal movement member are connected by a wire.

  The catheter according to the present invention is characterized in that, in the above-mentioned invention, the moving operation member and the internal moving member are connected by a tube material.

  In the catheter according to the present invention as set forth in the invention described above, the flow path communicating the at least one side opening portion and the proximal end is a groove provided on a side surface of the internal movement member. To do.

  In the catheter according to the present invention as set forth in the invention described above, the flow path that communicates the at least one side opening and the proximal end is a conduit provided inside the internal moving member. And

  In the catheter according to the present invention as set forth in the invention described above, the internal movement member has a cylindrical shape, and the flow path communicating the at least one side surface opening portion and the proximal end side is provided in the internal movement member. It includes the cylindrical internal space.

  In the catheter according to the present invention as set forth in the invention described above, the flow path communicating the at least one side opening portion and the proximal end side is a plurality of independent flow paths.

  In the catheter according to the present invention as set forth in the invention described above, the inner moving member can be moved in the axial direction of the outer cylinder and / or rotated around the axis of the outer cylinder by operating the moving operation member. It is characterized by being.

  The catheter according to the present invention is characterized in that, in the above-mentioned invention, the outer cylinder and / or the movement operation member is provided with an index indicating a movement amount and / or a rotation amount of the inner movement member. To do.

  According to the present invention, the drug administration distribution is changed by changing the overlapping state of the side hole and the at least one side opening by the movement of the internal movement member in the internal channel. Even if it does not perform etc., distribution of dosages, such as a chemical | medical agent, can be changed simply and rapidly.

FIG. 1 is a schematic diagram showing a configuration of a catheter according to Embodiment 1 of the present invention. FIG. 2 is a perspective view showing the configuration of the internal movement member of the catheter according to the first modification of the first embodiment of the present invention. FIG. 3 is a perspective view showing the configuration of the internal movement member of the catheter according to the second modification of the first embodiment of the present invention. FIG. 4 is a perspective view showing the configuration of the internal movement member of the catheter according to the third modification of the first embodiment of the present invention. FIG. 5 is a perspective view showing the configuration of the internal movement member of the catheter according to Modification 4 of Embodiment 1 of the present invention. FIG. 6 is a perspective view showing the configuration of the internal movement member of the catheter according to the fifth modification of the first embodiment of the present invention. FIG. 7 is a perspective view showing the configuration of the internal movement member of the catheter according to the sixth modification of the first embodiment of the present invention. FIG. 8 is a schematic diagram showing the configuration of the catheter according to the second embodiment of the present invention. FIG. 9 is a schematic diagram showing the configuration of the slide member of the catheter according to the third embodiment of the present invention. FIG. 10 is a schematic diagram showing a configuration of a catheter according to Embodiment 4 of the present invention. FIG. 11 is an explanatory diagram showing an example of a change in drug administration distribution.

  Hereinafter, with reference to drawings, the catheter which is a form for carrying out this invention is explained.

(Embodiment 1)
FIG. 1 is a schematic diagram showing a configuration of a catheter according to Embodiment 1 of the present invention. The catheter 1 has an outer cylinder 2 and a slide member 3. As shown in FIG. 1, the outer cylinder 2 has an inner channel 4 and at least one side hole 5 that penetrates the inner channel 4 and the outside. In the first embodiment, a plurality of side holes 5 are provided. A flange portion 6 is provided at the base end portion of the outer cylinder 2.

  The slide member 3 has an internal movement member 7, and the internal movement member 7 is disposed so as to be movable in a state in which the side surface is in close contact with the internal channel 4. The movement of the internal movement member 7 includes movement including forward movement and backward movement of the outer cylinder 2 in the axial direction and rotation around the axis of the outer cylinder 2. The internal moving member 7 is connected to the moving operation member 8 by a wire 12 such as a rod or a wire. In addition, in FIG. 1, although the wire 12 is one, a several wire may be sufficient.

  The movement operation member 8 is used for the movement operation of the internal movement member 7 in the internal channel 4. The moving operation member 8 includes a stopper portion 9, an operation knob 10, and a medicine injection portion 11. The plug portion 9 is partly or wholly inserted into the internal channel 4, and moves in the internal channel 4 while being connected to the internal moving member 7 in a state where the side surface is in close contact with the internal channel 4. The operation knob 10 is a part to be gripped when the operator moves the slide member 3 with the intention of moving the internal moving member 7. The drug injection part 11 has a cylindrical shape protruding from the operation knob 10 toward the proximal end, and a drug passage 13 penetrating from the proximal end surface of the drug injection part 11 to the distal end surface of the plug part 9 is provided. Yes.

  The internal movement member 7 is provided with a flow path 14 that communicates at least one side surface opening portion 15 provided on only a part of the side surface with the base side opening portion 16. This flow path 14 is a groove provided on a side surface. Further, the internal movement member 7 is also provided with a flow path 17 that allows the distal end side and the proximal end side to communicate with each other. The flow path 17 is in the internal channel 4 and has a function of keeping the pressure on the distal end side and the proximal end side of the internal moving member 7 substantially constant.

  Here, when the slide member 3 is inserted into the inner channel 4 of the outer cylinder 2, the slide member 3 is combined with the outer cylinder 2 in a state where it can be advanced, retracted, and rotated about its axis. In the movement range, at least a part of the internal movement member 7 in the internal channel 4 is included in a range located in a region where the side hole 5 is provided.

  In addition, as a material of the outer cylinder 2, the internal moving member 7, and the moving operation member 8, polyurethane, elastic silicon, Teflon (registered trademark), polyvinyl chloride, polyethylene, or the like can be used. Moreover, as a material of the wire 12, stainless steel etc. can be used.

  Next, the operation of the catheter 1 will be described. First, the operator connects a drug pump or the like to the drug injection unit 11 and injects the drug into the catheter 1. The injected medicine enters the space of the inner channel 4 of the outer cylinder 2 that spreads around the wire 12 through the medicine passage 13, and further flows from the opening 16 on the proximal end side of the inner moving member 7 to the flow path 14. It passes through the side opening 5, reaches the side opening 15, and overlaps with the side opening 15, and is administered into the living tissue.

  Here, when the operator wants to change the distribution of the dose of the medicine, the movement operation member 8 of the slide member 3 is operated. Specifically, the operation knob 10 is held and the moving operation member 8 is moved forward / backward or turned. By this operation, since the movement operation member 8 is connected to the internal movement member 7 by the wire rod 12, the internal movement member 7 also moves forward / backward and rotates. In addition, since the flow path 17 mentioned above makes the pressure of the front end side and the base end side substantially the same, the force required for the movement of the internal movement member 7 in the internal space 4 can be reduced. Further, when the medicine is discharged, the fluid 17 does not cause the internal space 4 on the distal end side to be in a negative pressure state due to the movement of the internal moving member 7, so that the body fluid enters the catheter 1. Can be prevented.

  The side opening portion 15 of the internal movement member 7 is provided only in a part of the side surface, and the side hole 5 of the outer cylinder 2 has a predetermined position and size. Thus, the overlapping state of the side opening 15 and the side hole 5 changes. Here, since the medicine is discharged from the side opening 15 to the living tissue through the side hole 5, the overlapping region of the side opening 15 and the side hole 5 becomes a cross section of the medicine passage. Therefore, since the change in the size of the overlapping region is a change in the cross-sectional area of the medicine passage, the amount of medicine discharged changes. That is, when the internal movement member 7 is moved to change the overlapping state of the side surface opening portion 15 and the side surface hole 5, the discharge amount of the medicine changes accordingly.

  The change state of the overlapping state of the side opening 15 and the side hole 5 includes a case where the size of the overlapping region is enlarged, a case where the size of the overlapping region is reduced, or a case where the overlapping state is changed to a non-overlapping state. (Discharge of medicine stops at this time) or changes from a non-superimposed state to a superposed state (discharge of medicine is started at this time).

  In the first embodiment, there are a plurality of side holes 5 at various positions of the side end portion of the outer cylinder 2, and there are a plurality of side opening portions 15 on the side surface of the internal moving member 7. For this reason, by the movement of the internal movement member 7, the overlapping state of the plurality of side holes 5 and the plurality of side surface opening portions 15 can be changed variously, and thereby the discharge state of the medicine can be changed variously. .

  At least one of the outer cylinder 2 and the movement operation member 8 is provided with an index indicating the movement amount of the inner movement member 7. For example, the outer cylinder 2 is provided with an index MC indicating the amount of movement in the rotational direction around the axis, and the movement operation member 8 includes an index MA indicating the amount of movement in the axial direction and an index indicating the amount of movement around the axis. MB is provided. The operator can remotely grasp the relative movement between the outer cylinder 2 and the moving operation member 8, that is, the relative movement relationship between the outer cylinder 2 and the inner movement member 7 by using these indicators MA, MB, and MC. be able to.

(Modification 1 of Embodiment 1)
Next, Modification 1 of Embodiment 1 will be described. In the first modification, as shown in FIG. 2, a side opening portion 25 is provided in which the side opening portion 15 of the internal moving member 7 is widened. Since the side surface opening portion 25 has a larger contact area with the inner surface of the internal channel 4 on the side surface than the side surface opening portion 15, the discharge state of the medicine is greatly changed by the forward / backward movement of the internal movement member 7. Can be made.

(Modification 2 of Embodiment 1)
Next, a second modification of the first embodiment will be described. In the second modification, as shown in FIG. 3, two side surface opening portions 35 a and 35 b in which the side surface opening portion 15 of the internal movement member 7 is widened are provided, and the side surface opening portions 35 a and 35 b do not overlap in the axial direction. They are provided at different positions and are provided at different positions that do not overlap with respect to the axis. For this reason, the discharge state of the medicine can be greatly changed by the rotation of the internal moving member 7.

(Modification 3 of Embodiment 1)
Next, a third modification of the first embodiment will be described. In the third modification, as shown in FIG. 4, instead of the channel 14 and the channel 17 having a groove structure provided in the internal moving member 7, a channel 44 and a channel 40 having a pipe structure are used. Also with the flow path 44 having this pipe line structure, the side surface opening portion 45 corresponding to the side surface opening portion 15 and the opening portion 46 corresponding to the base side opening portion 16 can be communicated with each other. Further, the proximal end side and the distal end side can be communicated with each other also by the flow path 40.

(Modification 4 of Embodiment 1)
Next, a fourth modification of the first embodiment will be described. In the fourth modification, as shown in FIG. 5, instead of the linear flow path 14 provided in the internal moving member 7, a flow path 50 having a groove structure formed in a spiral shape on the side surface is used. The spiral channel 50 can realize the functions of the plurality of channels 14 and the channel 17 in the first embodiment with one channel. Of course, a plurality of flow paths 50 may be provided, or a flow path 14 that does not communicate with the distal end side may be further provided. Furthermore, the pipe line 50 may not be spiral, and may be a flow path in which both the axial direction and the axial direction change sequentially.

(Modification 5 of Embodiment 1)
Next, a fifth modification of the first embodiment is described. In this modified example 5, as shown in FIG. 6, the internal moving member 7 is formed in a cylindrical shape, and the internal space of this cylinder is used as a flow path 60. The cylinder is provided with a side opening 65, and on the base end face, a support 61 that supports the wire 12 and an opening corresponding to the opening 16 in the other end surface region of the support 61. A portion 66 is formed. On the other hand, the end surface on the front end side is in an open state, and an open portion 62 that realizes a function corresponding to the flow path 17 is formed. The flow path 60 has a plurality of flow paths as a common flow path and realizes the functions of the flow paths 14 and 17.

(Modification 6 of Embodiment 1)
Next, a sixth modification of the first embodiment will be described. In this modified example 6, as shown in FIG. 7, instead of the side surface opening part 65 of the modified example 5, a side surface opening part 75 that gradually spreads from the base end side of the flow channel 60 toward the distal end side is formed. In this case, the opening portion 72 on the distal end side of the flow path 60 has an arc shape.

(Embodiment 2)
Next, a second embodiment of the present invention will be described. In Embodiment 1 mentioned above, between the internal movement member 7 and the movement operation member 8 was connected with the wire 12, but in this Embodiment 2, it replaced with the wire 12 as shown in FIG. A tube material 112 is used. When the wire 12 is used, a flow path is formed between the inner space 4 and the wire 12, but in the second embodiment, the outer diameter of the tube is substantially the same as the inner diameter of the inner space 4, and the sliding is performed. An internal passage 114 in the pipe material 112 formed as a flow path is used as a flow path. By using such a pipe material 112, the transmission of force between the internal movement member 47 on the distal end side corresponding to the internal movement member 7 and the movement operation member 8 on the proximal end side is further ensured, and the movement operation member Since it is not necessary to always insert 8 into the internal space 4, the axial movement range of the internal moving member 4 can be greatly expanded. The outer diameter of the tube material 114 may be smaller than the inner diameter ratio of the inner space 4 in the middle thereof.

(Embodiment 3)
Next, a third embodiment of the present invention will be described. In the first and second embodiments described above, the wire 12 or the tube material 112 forms a common flow path between the internal moving member 7 and the moving operation member 8, but in this third embodiment, The flow paths of the internal movement member 7 are independently connected to the movement operation member 8 side.

  That is, as shown in FIG. 9, the third embodiment includes a slide member 203 that extends from the proximal end side of the internal moving member 7 to the proximal end side of the moving operation member 8. The slide member 203 has a distal end side corresponding to the internal movement member 7 and a proximal end side corresponding to the movement operation member 8. However, in the part corresponding to the movement operation member 8, each flow path forms a plurality of open portions 146a to 146c, 140a that are independent on the base end side. For example, the flow paths 144a to 144c corresponding to the flow path 44 in FIG. 4 are independently opened from the side surface opening portions 145a to 145c corresponding to the side surface opening section 45 in FIG. 146a to 146c are formed, and the flow path 140 corresponding to the flow path 40 in FIG. 4 is formed to extend from the distal end side to the open end 140a on the proximal end side.

  When the slide member 203 forms such an independent flow path, the function of each flow path can be made independent. For example, the ejection of the medicine and the suction of the body fluid can be performed independently and simultaneously.

(Embodiment 4)
Next, a fourth embodiment of the present invention will be described. In the fourth embodiment, a drug injection part 311 corresponding to the drug injection part 11 is provided on the side surface of the outer cylinder 2. That is, in the first embodiment, the flow path is formed between the wire 12 and the inner space 4 of the outer cylinder 2, but the movement of the outer cylinder 2 is not performed with respect to the flow path without the movement operation member 8. They are connected directly from the side.

  In the fourth embodiment, since the operation by the moving operation member 8 and the drug injection portion are separated, the operability with respect to the movement operation member 8 can be improved, and the drug injection portion 311 is provided in the outer cylinder 2 that does not move. Since they are connected, the connection between the external drug injection tube and the drug injection part 311 can be stabilized.

(An example of changing the drug administration distribution)
Here, an example of changing a specific drug administration distribution will be described. Here, the outer cylinder 2 and the internal moving member 67 shown in FIG. 6 will be described as examples. 11 (a) shows the axial position of the side hole 5 provided in the outer cylinder 2, and FIG. 11 (b) is a circumferential development view of the outer cylinder 2, and FIGS. e) is a development view in the circumferential direction of the internal movement member 67 in which the position in the axial direction is changed.

  As shown in FIG. 11 (b), side holes 5 having the same diameter are respectively provided at positions # 1, # 2, # 3, # 4, and # 5 of the outer cylinder 2 in the axial direction shown in FIG. 11 (a). Two, two, four, two and two are provided in the radial direction of the outer cylinder. On the other hand, the inner moving member 67 is formed with side opening portions 65 which are the same as the arrangement positions of the side holes 5 of the outer cylinder, but are shifted in the axial positions of the positions # 1 to # 5. That is, the internal moving member 67 has the same circumferential angle and the same inner diameter as the two side holes 5 at the positions # 2 and # 4, starting from the position # 3, and shifted by a distance d1 to the tip side. Two side opening portions 65 are formed. Further, the internal movement member 67 has the same circumferential angle and the same inner diameter as the two side holes 5 at the positions # 1 and # 5 starting from the position # 3 in the axial direction, and has a distance d2 on the tip side. Two shifted side surface openings 65 are formed.

  Here, as shown in FIG. 11C, the four side holes 5 at the position # 3 of the outer cylinder 2 and the four side surface opening portions 65 corresponding to the position # 3 of the internal movement member 67 coincide with each other. Since the positions of the other side holes 5 and the side opening portions 65 do not coincide with each other, the drug is administered only from the four side holes 5 at the position # 3 of the outer cylinder 2.

  Next, as shown in FIG. 11 (d), when the internal moving member 67 is shifted by the distance d1 toward the proximal end side, the medicine can be administered only from the side holes 5 at the positions # 2 and # 4 of the outer cylinder 2. become. Furthermore, as shown in FIG. 11 (e), when the internal moving member 67 is shifted by the distance d2 toward the proximal end side, the medicine can be administered only from the side holes 5 at the positions # 1 and # 5 of the outer cylinder 2. Become.

  That is, in the example shown in FIG. 11, by distributing the internal movement member 67 in three stages in the axial direction of the outer cylinder 2, the distribution of drug administration through the side hole 5 of the outer cylinder 2 is centered on the position # 3. Shift in both axial directions. In addition, in this case, when the discharge pressure is the same, the number of side holes 5 to which the drug can be administered is always four, so that the drug dose is constant regardless of the shift.

  In the first to fourth embodiments described above, it is preferable to provide a lock mechanism between the flange member 6 and the operation knob 10 so that the movement of the internal movement member 67 relative to the outer cylinder 2 can be locked.

DESCRIPTION OF SYMBOLS 1 Catheter 2 Outer cylinder 3,203 Slide member 4 Internal channel 5 Side hole 6 Flange part 7,67 Internal movement member 8 Movement operation member 9 Plug part 10 Operation knob 11,311 Drug injection part 12 Wire material 13 Drug channel 14,17, 40, 44, 50, 60, 140, 144a to 144c Flow path 15, 25, 35a, 35b, 45, 65, 75, 145a to 145c Side opening portion 16, 46, 62, 66, 72, 140a, 146a to 146c Open part 61 Support part 12 Pipe 114 Internal passage MA, MB, MC Index

Claims (10)

An elongate tubular outer tube having an internal channel and at least one side hole extending between the internal channel and the exterior;
An internal moving member that is disposed so as to be movable in a state in which the side surface is in close contact with the inner surface of the internal channel, and in which a flow path that connects at least one side surface opening portion provided on a part of the side surface and the base end side is formed; ,
A movement operation member for performing a movement operation of the internal movement member in the internal channel;
With
The catheter is characterized in that the overlapping state of the side hole and the at least one side opening is changed by the movement of the internal moving member in the internal channel.   The catheter according to claim 1, wherein the internal movement member is formed with a communication channel that communicates a distal end side and a proximal end side.   The catheter according to claim 1, wherein the moving operation member and the internal moving member are connected by a wire.   The catheter according to claim 1, wherein the moving operation member and the internal moving member are connected by a tube material.   2. The catheter according to claim 1, wherein the flow path communicating the at least one side opening portion and the proximal end side is a groove provided on a side surface of the internal movement member.   2. The catheter according to claim 1, wherein the flow path that communicates the at least one side opening portion and the proximal end side is a conduit provided inside the internal moving member.   The internal movement member has a cylindrical shape, and the flow path that communicates the at least one side opening portion and the proximal end side includes the cylindrical internal space in the internal movement member. Item 10. The catheter according to Item 1.   2. The catheter according to claim 1, wherein the flow path connecting the at least one side opening portion and the proximal end side is a plurality of independent flow paths.   2. The catheter according to claim 1, wherein the inner moving member is capable of moving in the axial direction of the outer cylinder and / or rotating around the axis of the outer cylinder by operation of the moving operation member. .   The catheter according to claim 1, wherein the outer cylinder and / or the movement operation member is provided with an index indicating a movement amount and / or a rotation amount of the inner movement member.

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