JP2010158672A - Bubble generation method, bubble generation apparatus, and ozone water producing method - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To efficiently dispersively generate fine bubbles in an aqueous liquid flow using a low concentration chemical. <P>SOLUTION: In a bubble generation method by introducing gas into the aqueous liquid flow, and dispersing the introduced gas into the aqueous liquid flow as fine bubbles, the chemical assisting the dispersion of the fine bubbles into the aqueous liquid flow is charged into the aqueous liquid flow before introducing the gas, and a chemical containing an organic compound with a water/octanol distribution coefficient LogP of at least 0-2.3 is charged into the aqueous liquid flow from a chemical charge part upstream of a gas generation part to generate bubbles by introducing gas into the aqueous liquid flow, before the chemical uniformly dissolves into the aqueous liquid flow. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  The present invention relates to a bubble generation method and a bubble generation device for generating fine bubbles dispersed in an aqueous liquid flow, and an ozone water generation method for generating ozone water using such a bubble generation method or bubble generation device. .

  Conventionally, as a method of generating bubbles in an aqueous liquid flow such as water, a method of jetting a gas into an aqueous liquid flow from a minute hole such as a nozzle or a perforated plate, a method of entraining a gas on the liquid surface in a jet flow, or a high speed There is a method using a shearing force such as blowing a gas in a liquid flow. In addition to the mechanical bubble generation method, there is a method using a surfactant or the like as a chemical bubble generation method.

  For example, Patent Literature 1 listed below discloses a technique for obtaining fine bubbles using a surfactant and an antifoaming agent and facilitating extinction of the generated bubbles in a bubbly water flow generator that ejects a bubbly water flow into a water tank. It is disclosed.

  On the other hand, the following Patent Document 2 specifies a bubble generation device and a bubble generation method that include a bubble generation tank, water contained in the tank, and bubble generation means for generating bubbles in the water. By using water containing an organic carboxylic acid, a technique has been disclosed in which finer bubbles can be obtained and the bubbles floating on the liquid surface disappear immediately.

  On the other hand, Patent Document 3 below discloses a technique for releasing microbubbles while suppressing coalescence of a large number of microbubbles generated by the action of a surfactant.

  By the way, such a bubble generating method is applied, for example, when generating ozone water in which ozone is dissolved and dispersed in water. In this case, since ozone has a characteristic that it is difficult to dissolve in water, it is possible to dissolve more ozone in water by dispersing ozone gas in water as finer bubbles. That is, when generating ozone water, it is preferable to introduce ozone gas into water and to generate fine bubbles by dispersing the ozone gas in water.

  For this reason, a chemical that assists the dispersion of fine bubbles in water is also introduced. For example, Patent Document 4 below discloses that ozone water is generated while water in which a chemical is dissolved is poured into a tank and bubbles of ozone gas are blown using an air diffuser.

  However, in the conventional method, if the amount of the drug added is not increased, bubble miniaturization may not be promoted, or the drug may react with ozone and ozone may be used wastefully. In particular, there has been no consideration of efficiently generating fine bubbles by dispersing them in a liquid using a low-concentration drug.

JP-A-4-279163 JP 2004-283683 A Japanese Patent Laid-Open No. 2003-230824 International Publication No. 07/040260 pamphlet

The present invention has been proposed in view of such conventional circumstances, and it is possible to efficiently generate fine bubbles by dispersing them in an aqueous liquid flow using a low-concentration drug. The object is to provide a method and a bubble generator.
Another object of the present invention is to provide an ozone water generation method that can efficiently generate ozone water using such a bubble generation method or bubble generation device.

  In order to achieve the above object, the invention according to claim 1 is a bubble generation method in which a gas is introduced into an aqueous liquid stream and the introduced gas is dispersed as fine bubbles in the aqueous liquid stream and generated. Before introducing the gas into the aqueous liquid stream, the agent for assisting the dispersion of fine bubbles is introduced into the aqueous liquid stream, and before the agent is uniformly dissolved in the aqueous liquid stream, At least the water / octanol partition coefficient LogP is 0 or more and 2.3 in the aqueous liquid stream from the drug introduction part upstream of the gas generation part so that gas is introduced into the aqueous liquid stream to generate bubbles. A method for generating bubbles, characterized in that a chemical containing an organic compound as described below is introduced.

  In the invention according to claim 2, the Reynolds number of the aqueous liquid stream is 3000 or more and less than 200,000, and the residence time until the medicine thrown into the aqueous liquid stream from the medicine throwing section reaches the bubble generating section is increased. The bubble generation method according to claim 1, wherein the bubble generation time is 1 second or less.

  The invention according to claim 3 is characterized in that water is introduced as an aqueous liquid and a gas containing any of ozone, nitrogen, oxygen, and air is introduced as a gas. It is the bubble generation method described.

  The invention according to claim 4 is the method for generating bubbles according to any one of claims 1 to 3, wherein the medicine is put into an aqueous fluid stream in the form of an aqueous solution.

  In the invention according to claim 5, the drug is at least one selected from triacetin, diacetoxypropane, butanediol diacetate, pentanediol diacetate, butyl acetate, propyl acetate, propanol, butanol, and pentanol. It is a bubble generation method as described in any one of Claims 1-4 including a seed | species or 2 or more types.

  The invention according to claim 6 is characterized in that the drug contains at least one or more selected from triacetin, diacetoxypropane, butanediol diacetate, and pentanediol diacetate. Item 5. The bubble generation method according to any one of Items 1 to 4.

  In the invention according to claim 7, the concentration of the drug contained in the aqueous solution when being introduced into the aqueous liquid stream is set to 100 by mass ratio with respect to the concentration of the drug contained in the aqueous liquid in which bubbles are generated. The bubble generation method according to any one of claims 1 to 6, wherein the bubble generation method is at least twice and at most 10,000 times.

  The invention according to claim 8 is a bubble generating device that introduces a gas into an aqueous liquid flow and generates the dispersed gas as fine bubbles dispersed in the liquid. A gas introduction path for introducing gas, a bubble generating section for introducing gas into an aqueous liquid stream to generate bubbles, a gas-liquid discharge path for discharging aqueous liquid containing bubbles, and dispersion of fine bubbles And a medicine introduction section for introducing a medicine for assisting the medicine, the medicine introduction section is connected to a liquid introduction path upstream of the bubble generation section, and the medicine has at least a water / octanol distribution coefficient LogP of 0 or more; It is a bubble generator characterized by including the organic compound which is 3 or less.

  The invention according to claim 9 is the bubble generation device according to claim 8, wherein the bubble generation unit generates bubbles using any means of an ejector, an air diffuser, and mechanical shearing. .

  In the invention according to claim 10, the Reynolds number in the liquid introduction path is 3000 or more and less than 200000, and the residence time until the medicine thrown into the aqueous liquid flow from the medicine throwing section reaches the bubble generating section. The bubble generating device according to claim 8 or 9, wherein is 1 second or less.

  The invention according to claim 11 is an ozone water generation method for generating ozone water by introducing ozone gas into water and dissolving and dispersing ozone in the water. An ozone water generating method characterized in that ozone water is generated using the bubble generating method or the bubble generating device described.

  As described above, in the present invention, before introducing the gas into the aqueous liquid stream, the drug for assisting the dispersion of fine bubbles is introduced into the aqueous liquid stream, and this drug is added to the aqueous liquid stream. By introducing gas into the aqueous liquid stream and generating bubbles before uniform dissolution, fine bubbles are efficiently dispersed in the liquid using a lower concentration of medicine than before. It is possible to make it. Therefore, by using the present invention and dispersing ozone gas in water as finer bubbles, it is possible to efficiently generate ozone water in which ozone is dissolved and dispersed in water.

FIG. 1 is a block diagram showing an example of an ozone water generator to which the present invention is applied. FIG. 2 is a schematic diagram showing a configuration of the bubble generation unit, where (a) is an ejector, (b) is an air diffuser, and (c) is a case where mechanical shearing is used. FIG. 3 is a block diagram showing a specific example of an ozone generator. FIG. 4 is a block diagram illustrating a specific example of the medicine input unit. FIG. 5 is a schematic diagram showing the experimental apparatus used in the first embodiment. FIG. 6 is a photograph of the inside of the water tank when the medicine is introduced from the position A in FIG. FIG. 7 is a photograph of the inside of the water tank when the medicine is introduced from the position B in FIG. FIG. 8 is a schematic diagram showing an experimental apparatus used in the third embodiment.

Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings.
In the present embodiment, a case where the bubble generation method or the bubble generation apparatus according to the present invention is applied to generation of ozone water will be described as an example.

First, a bubble generation method to which the present invention is applied will be described.
The bubble generation method to which the present invention is applied is a bubble generation method in which a gas is introduced into a liquid, a gas is introduced into an aqueous liquid flow, and the introduced gas is dispersed in the aqueous liquid flow as fine bubbles. Before introducing the gas into the aqueous liquid stream, before introducing the drug for assisting the dispersion of fine bubbles into the aqueous liquid stream, and before the drug is uniformly dissolved in the aqueous liquid stream 1. At least the water / octanol partition coefficient LogP is 0 or more in the aqueous liquid stream from the drug introduction part upstream of the gas generating part so that gas is introduced into the aqueous liquid stream to generate bubbles. A drug containing an organic compound that is 3 or less is introduced.

  Here, the aqueous liquid used in the present invention is not particularly limited as long as it is a liquid mainly composed of water, but preferably contains 95% by mass or more of water, and contains 99.5% by mass or more of water. Is more preferable, and water is still more preferable. Examples of water include tap water, ion exchange water, seawater, and ultrapure water.

  Further, as the aqueous liquid, in addition to the above-described water, a compound having a water / octanol partition coefficient LogP of less than 0, such as ethanol, glycerin, saccharides, salts, polyethylene glycol, and the like can be used within the range where the effects of the present invention are achieved. What is included can be used.

  It is preferable to use a drug containing an organic compound having a water / octanol partition coefficient LogP of 0 or more and 2.3 or less as an agent for assisting the dispersion of bubbles. Moreover, in order to obtain a more excellent bubble dispersion effect, it is preferable to use a drug having low solubility in water, and more specifically, a drug having a Log P of 0.2 or more is more preferably used. On the other hand, in order to exhibit the bubble dispersion effect, appropriate water solubility is required. Moreover, when using a chemical | medical agent as aqueous solution, in order not to isolate | separate an organic compound from this aqueous solution but to maintain a higher concentration aqueous solution, it is more preferable to use the chemical | medical agent whose LogP is less than 1.9.

  In addition, a small amount of surfactant may be added to the water-soluble liquid so that the foam is not stabilized for improving wettability. Examples of the surfactant include polyglycerin fatty acid ester, glycerin fatty acid ester, polyoxyethylene sorbitan fatty acid ester, sucrose fatty acid ester, alcohol ethoxylate, fatty acid and salt thereof, linear alkylbenzene sulfonic acid and salt thereof, and alkyl sulfate. Examples thereof include salts and polyoxyethylene alkyl sulfates. Among them, in particular, those having an alkyl chain having 10 or less carbon atoms can be suitably used because of their low stability as foam. For example, the addition of monocaprylin is very effective in improving wettability.

  Specific examples of the drug used include, for example, triacetin, monobutyrin, diacetoxypropane, butanediol diacetate, pentanediol diacetate, propyl formate, methyl acetate, butyl acetate, propyl acetate, pentyl acetate, and 3-methylbutyl acetate. Having an ester group such as propanol, butanol, pentanol, having a hydroxyl group such as 2-phenoxyethanol, having a carbonyl group such as 4-methyl-2-pentanone, 2-butanone, methyl ethyl ketone, methyl isobutyl ketone, Those having an ether group such as 1-ethoxy-2-propanol acetate, 2- (2-n-butoxyethoxy) ethyl acetate, butyl carbitol, butyl cellosolve, cellosolve acetate are excellent. In addition, since the reactivity with ozone is low, for example, esters such as triacetin, diacetoxypropane, butanediol diacetate, pentanediol diacetate, propyl formate, methyl acetate, butyl acetate, propyl acetate, pentyl acetate Are better. Furthermore, triacetin having two or more less volatile ester groups, diacetoxypropane, butanediol diacetate, pentanediol diacetate and the like are preferable, and among them, triacetin (boiling point 259 ° C.) having very low volatility is preferable. Most preferred. Although these chemical | medical agents can be used in the state of undiluted | stock solution or aqueous solution, it is preferable to use as aqueous solution at the point which is easy to introduce | transduce a smaller amount of chemical | medical agents quantitatively.

  In addition, although several calculation methods are known about water / octanol distribution coefficient LogP, the value calculated from the simulation by the computer was used as LogP in this invention. Specifically, LogP prediction software ACD / LogP DB manufactured by Advanced Chemistry Development (ACD / Labs) was used, and a value obtained by calculating LogP (water / octanol system partition coefficient) from the chemical structural formula was used.

  When applying the bubble generation method according to the present invention described above to the production of ozone water, before introducing the ozone gas into the water stream, the above-mentioned agent for assisting the dispersion of fine bubbles in the water stream is added, and Before this drug is uniformly dissolved in the water stream, ozone gas is introduced into the water stream to generate bubbles.

  Here, as a result of intensive studies to achieve the above object, the present inventors obtained the following knowledge (1) to (3), and at the same drug concentration, depending on the position at which the drug is introduced. It was found that the state of micronization of the bubbles changes greatly.

(1) Bubbles were refined when a drug was introduced at a position close to an aspirator (ejector) that introduces ozone gas into water, and bubbles were not refined when a drug was introduced at a distant position.
(2) When the drug was introduced as an aqueous solution and the drug was introduced as a stock solution (high concentration) even at a position far from the aspirator where the bubble was not refined, the bubble was refined.
(3) Compared with the method (Method A) in which the water in which the chemical is dissolved is poured into a tank and ozone gas bubbles are blown using an air diffuser, ozone gas is continuously blown into the water stream by an aspirator. In the method of generating ozone water (method B), bubbles could be refined with a lower concentration of chemical.

  Although the reason is not clear from the findings of (1) to (3) above, when the gas is introduced before the aqueous solution of the drug added to the water flow in the pipe is completely mixed and diluted, the bubbles become finer. It is thought to happen. In addition, when the drug is used in the state of a stock solution, it has been confirmed that bubbles are refined even if the drug is introduced from a position further away from the aspirator. This is considered to be because the drug could not be completely dissolved at the time when it was introduced into the aspirator because the drug dissolution rate was slow.

  From the above, in order to efficiently generate fine bubbles dispersed in an aqueous liquid stream using a low-concentration drug, before the drug is uniformly dissolved in the aqueous liquid stream, It was revealed that it was important to introduce gas into

  Therefore, in the bubble generation method to which the present invention is applied, before introducing the gas into the aqueous liquid stream, an agent for assisting the dispersion of fine bubbles is introduced into the aqueous liquid stream, and this agent is introduced into the aqueous liquid stream. Before being uniformly dissolved, for example, the concentration at the time of introducing the drug and the distance until it is introduced into the aspirator are adjusted so that the gas is introduced into the aqueous liquid flow.

  Specifically, the concentration of the drug contained in the aqueous drug solution when it is introduced into the aqueous liquid stream is 100 times or more in terms of mass ratio with respect to the concentration of the drug contained in the aqueous liquid in which bubbles are generated. It is preferable to make it less than twice. When the concentration of the drug contained in the drug aqueous solution is less than 100 times, the drug is easily dissolved uniformly before coming into contact with the gas, and the effect is remarkably reduced. On the other hand, when the concentration of the drug contained in the drug aqueous solution is more than 10,000 times, the amount to be charged becomes extremely small, and it may be difficult to control for supplying a certain amount into the aqueous fluid flow. Therefore, if it is the said numerical range, the refinement | miniaturization effect of the bubble by throwing in a chemical | medical agent can be acquired stably.

  As described above, in the bubble generation method to which the present invention is applied, before introducing the gas into the aqueous liquid stream, the agent for assisting the dispersion of fine bubbles is introduced into the aqueous liquid stream, and this agent is used. By introducing gas into the aqueous liquid stream and generating bubbles before it dissolves uniformly in the aqueous liquid stream, the fine bubbles can be efficiently liquefied with a lower concentration of medicine than before. It is possible to generate it by dispersing it inside.

Next, a bubble generator to which the present invention is applied will be described.
The bubble generating device to which the present invention is applied is, for example, applied to an ozone water generating device 10 as shown in FIG. 1, and this ozone water generating device 10 includes a liquid introduction path 11 for introducing water and ozone. A gas introduction path 12 for introducing air (hereinafter referred to as ozone gas), a bubble generation section 13 for introducing bubbles into water to generate bubbles, a gas-liquid discharge path 14 for discharging ozone water containing bubbles, And a drug loading unit 15 for loading a drug that assists in the dispersion of various bubbles.

  The liquid introduction path 11 is a pipe that guides water to the bubble generation unit 13, and is connected to, for example, a tap water faucet through a hose (not shown). Further, the liquid introduction path 11 is provided with a pressure reducing valve 16 so that the pressure of the supplied water can be adjusted within a predetermined range (for example, 0.15 to 0.3 MPa).

  The gas introduction path 12 is a pipe that guides ozone gas to the bubble generation unit 13, and sucks air from the outside via the air pump 17. Further, an ozone generator 18 that generates ozone is connected between the air pump 17 and the bubble generation unit 13 of the gas introduction path 12. Thereby, it is possible to supply ozone from the ozone generator 18 to the bubble generation unit 13 through the gas introduction path 12.

  Here, as a method for generating ozone, for example, there are a method using ultraviolet rays, a method using electrolysis of water, a method using discharge, and the like. Among them, it is preferable to use a method by discharge with good maintainability and a wide control range of ozone concentration. Moreover, when generating ozone by discharge, it is known that a lower dew point of the raw material gas is preferable for generating ozone, and a higher oxygen concentration is preferable.

  Specifically, as the ozone generator 18, for example, a configuration as shown in FIGS. In addition, about the structure of each part of the ozone generator 18 shown in FIG.3 (a)-(e), it is as having shown to (1)-(7) in FIG. That is, as the ozone generator 18, for example, a method of introducing pressurized air or pressurized oxygen using an oxygen cylinder or an air cylinder, a method of pumping air with a compressor or a pump, an oxygen concentrator (PSA), or the like. There are methods to improve the efficiency of ozone generation by concentrating oxygen, methods to dehumidify with an adsorbent such as silica gel and zeolite, and methods to use a membrane-type air dryer using a water vapor permeable membrane. What combined suitably can be used.

  In addition, when the ozone concentration is high, the amount of ozone generated while controlling the voltage of the discharge part and the number of discharges, the method of diluting with a gas inert to ozone such as air, oxygen, nitrogen and carbon dioxide There is a method to suppress it. Moreover, as a gas to dilute, the one where a dew point is low is preferable from the stability of ozone.

  The bubble generating unit 13 is constituted by a T-shaped tube, and the liquid inlet 11 is connected to the inlet of the T-shaped tube, the gas-liquid outlet 14 is connected to the outlet, and the gas inlet 12 is connected to the inlet. . In addition, the bubble generation unit 13 is configured by an aspirator (ejector) 13A as shown in FIG. 2A, for example, to introduce ozone gas into water and disperse the introduced ozone gas as fine bubbles in water. Yes. In other words, the aspirator 13A has a configuration in which the throttle portion 13a is provided in the above-described T-shaped tube, generates a pressure difference in the direction in which water containing ozone gas flows, and generates a large number of microbubbles by a shock wave generated at that time. It is possible.

  The bubble generating unit 13 is not necessarily limited to such a configuration of the aspirator 13A. For example, a configuration in which an air diffuser 13B that generates micro bubbles in a T-shaped tube as shown in FIG. 2B is arranged. Alternatively, it is also possible to arrange the propeller 13C in a T-shaped tube as shown in FIG. 2C and generate a microbubble by mechanical shearing by the rotation of the propeller 13C.

  The drug introduction unit 15 is connected to the liquid introduction path 11 upstream of the bubble generation unit 13 and introduces an aqueous solution (or stock solution) containing the drug into the water flowing through the liquid introduction path 11. Specifically, as shown in FIG. 4 (a), for example, the drug input unit 15 is connected to a T-tube (cheese) 20 disposed in the liquid introduction path 11 by connecting a pump 19 such as a tube pump, The medicine pumped by the pump 19 via the T-tube 20 can be introduced into the water flowing through the liquid introduction path 11. As shown in FIG. 4 (b), the drug introduction unit 15 has an aspirator (ejector) 21 disposed in the liquid introduction path 11, and the drug is introduced into the water flowing through the liquid introduction path 11 via the aspirator 21. It can also be set as the structure to introduce. Further, as shown in FIG. 4 (c), the medicine injection section 15 is provided with a branch path 11a branched from the liquid introduction path 11, and the structure shown in FIG. (The configuration shown in FIG. 4B may be used.) May be arranged, and the medicine may be introduced into the water flowing through the branch path 11a.

  In the ozone water generating apparatus 10, ozone water is dispersed in water as fine bubbles to generate ozone water in which ozone is dissolved and dispersed in water. The ozone water is discharged to the outside through the gas / liquid discharge path 14. In the case of the configuration shown in FIG. 4C, ozone water is introduced from the gas-liquid discharge passage 14 through the valve 22 into the liquid introduction passage 11 whose water amount is adjusted.

  By the way, in the ozone water generating apparatus 10 to which the present invention is applied, as shown in FIG. 1, the medicine charging unit 15 is connected to the liquid introduction path 11 upstream of the bubble generating unit 13. That is, in the ozone water generating apparatus 10, a chemical is introduced before the ozone gas is introduced into the water flow, and the chemical is introduced into the bubble generating unit 13 before the chemical is uniformly dissolved in the water flow. .

  As a result, it is possible to efficiently generate fine bubbles of ozone gas in water by using a medicine having a lower concentration than in the past. And in this ozone water generating apparatus 10, it is possible to dissolve more ozone in water by dispersing ozone gas in water as finer bubbles.

  Here, in the residence time until the medicine introduced from the medicine introduction section 15 is uniformly dispersed in the liquid introduction path 11, the solubility of the medicine to be added in water, specifically, the water / octanol distribution coefficient LogP. In addition, since it depends on the concentration of the drug in the case of charging with an aqueous solution, in order to obtain the effect of the present invention, it is possible to appropriately select the charging position and conditions according to the drug to be used and the drug concentration. .

  Specifically, in the ozone water generating apparatus 10, in order to stably obtain the bubble dispersion effect of the present invention, in the laminar flow region where the Reynolds number in the liquid introduction path 11 is less than 3000, the liquid introduction from the drug introduction unit 15 is performed. It is preferable that the residence time until the chemical | medical agent thrown in into the water flow in the path | route 11 arrives at the bubble generation part 13 shall be 1 second or less. In addition, in the turbulent flow region having a Reynolds number of 3000 or more in the liquid introduction path 11, uniform dispersion of the injected drug is likely to occur. In this case, in order to obtain the bubble dispersion effect of the present invention more stably, the residence time is preferably 0.15 seconds or less, and more preferably 0.1 seconds or less. On the other hand, setting the Reynolds number in the liquid introduction path 11 to 200,000 or more is not preferable because uniform dispersion of the charged drug is extremely likely to occur, and the effects of the present invention are hardly obtained.

  As described above, in the ozone water generation apparatus 10 to which the present invention is applied, ozone gas can be dispersed in water as finer bubbles, and therefore ozone water in which ozone is dissolved and dispersed is efficiently generated. Is possible.

In addition, this invention is not necessarily limited to the thing of the said embodiment, A various change can be added in the range which does not deviate from the meaning of this invention.
For example, the present invention is not limited to the case where the above-described ozone water is generated. For example, the present invention can also be applied to a case where a gas such as nitrogen, oxygen, air, or the like is generated as fine bubbles dispersed in a liquid.

  Hereinafter, the effects of the present invention will be made clearer by examples. In addition, this invention is not limited to a following example, In the range which does not change the summary, it can change suitably and can implement.

(First embodiment)
In the first example, for example, an experimental apparatus as shown in FIG. 5 was used to measure the generation state of bubbles when ozone gas was introduced into water depending on the position at which the medicine was introduced.

  Specifically, in this experimental apparatus, a pipe 32 having an inner diameter of 6 mm is connected to the inlet of an ejector (manufactured by ASONE, polytetrafluoroethylene (PTFE)) 31, and a spiral pump (manufactured by Elepon Chemical Co., Ltd.) is connected through the pipe 32. , SL-5SN) 33, water was introduced at 3 L / min. Further, a pipe 34 having an inner diameter of 4 mm was connected to the suction port of the ejector 31, and ozone-containing air (ozone gas) was introduced at 100 ml / min through the pipe 34 by an air pump (SSPP-2S, manufactured by Mizusaku Co., Ltd.). Further, one end of a pipe 36 having an inner diameter of 6 mm was connected to the outlet of the ejector 31, and the other end was placed in a water tank (3L acrylic water tank) 37 filled with water. And the water in the water tank 37 is discharged | emitted through the piping 38 outside.

  The injection position of the medicine was a position (A) 5 cm before the ejector 31 (10 cm from the centrifugal pump 33) and a position (B) 20 cm before the centrifugal pump 33. As the drug, a 6% by weight triacetin aqueous solution was used. This medicine was introduced at 1 mL / min from each position through a pipe having an inner diameter of 1 mm connected to a quantitative liquid feeding pump (manufactured by Tokyo Rika Co., Ltd., microtube pump MP-3).

  And the photograph which image | photographed the inside of the water tank 37 when a chemical | medical agent is thrown in from the position of A shown in FIG. 5 is shown in FIG.

  As shown in FIG. 6, it can be seen that when the drug is introduced from the position A, fine bubbles are dispersed and generated in water. It was also found that when the drug was introduced from the position A, the concentration of the drug was about 10 to 100 ppm and fine bubbles were dispersed and generated in water (by visual observation). The Re number at the position A was about 10,000, and the residence time to the ejector 31 was about 0.028 seconds.

  On the other hand, the photograph which image | photographed the inside of the water tank 27 when a chemical | medical agent is thrown in from the position of B shown in FIG. 5 is shown in FIG.

  As shown in FIG. 7, it can be seen that when the drug is introduced from the position B, the bubbles are rough and the dispersion of the bubbles is small. In addition, when the drug was introduced from the position B, it was found that the concentration of the drug was about 50 to 5000 ppm (by visual observation) in order to generate fine bubbles dispersed in water. The Re number at the position B was about 10,000, and the residence time until the ejector 31 was about 0.20 seconds.

(Second embodiment)
In the second example, 0.5% by weight aqueous solutions of various drugs of Examples 1 to 19 and Comparative Examples 1 to 14 having different water / octanol partition coefficients LogP were used, and the same as in the first example. Tests were conducted to evaluate “fineness of foam” and “separation of concentrate”. The evaluation results are shown in Tables 1 and 2.

  In Tables 1 and 2, “fineness of foam” is defined as “O” when the fineness is confirmed by visual observation, and “X” when the others are confirmed. On the other hand, “separation of concentrated liquid” was determined as ○ when the 0.5 wt% aqueous solution was prepared at 25 ° C., uniformly dissolved, △ when cloudy, and × when immediately separated. .

  As shown in Tables 1 and 2, in Examples 1 to 19, where the water / octanol partition coefficient LogP is within the numerical range of the present invention (0 ≦ LogP ≦ 2.3), the comparison is outside the numerical range of the present invention. It turns out that all show the favorable result compared with Examples 1-14. In Examples 14 and 15, although white turbidity was observed, good results were shown for making the bubbles finer, and therefore it was possible to disperse ozone gas as finer bubbles in water. .

(Third embodiment)
In the third example, for example, an experimental apparatus as shown in FIG. 8 was used to measure the bubble generation state and ozone concentration when the scale was expanded as compared with the experimental apparatus shown in FIG.

  Specifically, in this experimental apparatus, one end of a pipe 42 having an inner diameter of 28 mm is connected to the inlet of a magnet pump (Nikkiso Eiko Co., Ltd. CP-70) 41 and one end of a pipe 43 having an inner diameter of 28 mm is connected to the outlet. The other ends of the pipes 42 and 43 are placed in a water tank (160L polypropylene water tank) 44 filled with water. The water in the water tank 44 was circulated at 100 L / min by the magnet pump 41 through these pipes 42 and 43. In addition, one end of a pipe 46 having an inner diameter of 20 mm is connected to an inlet of an ejector (IBS, manufactured by polyvinylidene fluoride) 45, and one end of a pipe 47 having an inner diameter of 6 mm is connected to the outlet. By connecting the other end to the pipe 43, water branched from the pipe 43 through these pipes 46 and 47 was introduced into the ejector 45 at 30 L / min. Further, a pipe 48 having an inner diameter of 6 mm was connected to the suction port of the ejector 45, and ozone-containing air (ozone gas) supplied from the ozone generator 49 through this pipe 48 was introduced into the ejector 45 at 3 L / min.

  The injection position of the medicine was a position (A) 15 cm in front of the ejector 45 (30 cm from the magnet pump 41) and a position (B) 30 cm in front of the magnet pump 41. As the drug, a 5% by weight triacetin aqueous solution was used. This medicine was introduced at 16 mL / min from each position through a pipe having an inner diameter of 3.7 mm connected to a quantitative liquid feeding pump (manufactured by Tokyo Rika Co., Ltd., microtube pump MP-3). Furthermore, an experiment was also conducted when 160 mL of the drug was first uniformly dissolved in the water tank 44 (referred to as position (C)). At the position C, an amount of drug corresponding to 10 minutes after the start at the positions A and B was introduced.

  Then, the evaluation was made with respect to “fineness of bubbles” and “ozone concentration” when the drug was introduced from positions A, B, and C shown in FIG. The evaluation results are shown in Table 3.

  For “fineness of bubbles” in Table 3, the same evaluation method as in the second example was used. On the other hand, regarding the “ozone concentration”, the dissolved ozone monitor ELP-100 manufactured by Sugawara Jitsugyo was used while circulating water in the water tank 44 at 1 L / min using a liquid feed pump 7520-40 manufactured by Yamato Scientific Co., Ltd. The concentration of ozone dissolved in water was measured. The dissolved ozone concentration measured at this time is a value after 5 minutes from the operation. The ozone concentration in the ozone-containing gas supplied from the ozone generator 49 was adjusted to be constant at 0.5% by volume using EG-600 manufactured by Sugawara Jitsugyo Co., Ltd. The gas flow rate was adjusted to be constant at 3 L / min using a MODEL5100 mass flow controller manufactured by Cofrock.

  As shown in Table 3, when the drug was introduced from the positions B and C, the bubbles were not refined. When the drug was introduced from the position A, the bubbles were refined immediately after the introduction. The Re number at the position A was about 30000, and the residence time to the ejector 45 was about 0.09 seconds.

  DESCRIPTION OF SYMBOLS 10 ... Ozone water production | generation apparatus (bubble generator) 11 ... Liquid introduction path 12 ... Gas introduction path 13 ... Bubble generation part 14 ... Gas-liquid discharge path 15 ... Drug injection | pouring part

Claims (11)

A bubble generation method for introducing a gas into an aqueous liquid stream and dispersing the introduced gas as fine bubbles in the aqueous liquid stream to generate the gas,
Before introducing a gas into the aqueous liquid stream, a drug that assists the dispersion of fine bubbles is introduced into the aqueous liquid stream, and before the drug is uniformly dissolved in the aqueous liquid stream. In order to generate the bubbles by introducing the gas into the aqueous liquid stream, at least the water / octanol distribution coefficient LogP is 0 in the aqueous liquid stream from the drug introduction part upstream of the gas generating part. A method for generating bubbles, characterized in that a drug containing an organic compound that is 2.3 or less is charged.   The Reynolds number of the aqueous liquid stream is not less than 3000 and less than 200000, and the residence time until the medicine introduced into the aqueous liquid stream from the medicine introduction part reaches the bubble generation part is 1 second or less. The method for generating bubbles according to claim 1. Water is introduced as the aqueous liquid,
The bubble generation method according to claim 1 or 2, wherein a gas containing any of ozone, nitrogen, oxygen, and air is introduced as the gas.   The method for generating bubbles according to any one of claims 1 to 3, wherein the medicine is introduced into the aqueous fluid stream in the form of an aqueous solution.   The drug contains at least one or two or more selected from triacetin, diacetoxypropane, butanediol diacetate, pentanediol diacetate, butyl acetate, propyl acetate, propanol, butanol, and pentanol. The method for generating bubbles according to any one of claims 1 to 4, characterized in that:   The said chemical | medical agent contains at least 1 sort (s) or 2 or more types chosen from triacetin, diacetoxypropane, butanediol diacetate, and pentanediol diacetate, The any one of Claims 1-4 characterized by the above-mentioned. The method for generating bubbles as described in 1.   The concentration of the drug contained in the aqueous solution when charged into the aqueous liquid stream is 100 times or more and 10,000 times or less in terms of mass ratio with respect to the concentration of the drug contained in the aqueous liquid in which the bubbles are generated. The method for generating bubbles according to any one of claims 1 to 6, wherein: A bubble generating device that introduces a gas into an aqueous liquid flow and generates the dispersed gas as fine bubbles dispersed in the liquid,
A liquid introduction path for introducing the aqueous liquid;
A gas introduction path for introducing the gas;
A bubble generating part for introducing the gas into the aqueous liquid stream to generate the bubbles;
A gas-liquid discharge path for discharging the aqueous liquid containing the bubbles;
A drug charging unit for charging a drug that assists the dispersion of the fine bubbles,
The medicine injection section is connected to a liquid introduction path upstream of the bubble generation section;
The bubble generating apparatus, wherein the chemical contains at least an organic compound having a water / octanol partition coefficient LogP of 0 or more and 2.3 or less.   The bubble generating apparatus according to claim 8, wherein the bubble generating unit generates bubbles using any means of an ejector, an air diffuser, and mechanical shearing.   The Reynolds number in the liquid introduction path is not less than 3000 and less than 200000, and the residence time until the medicine introduced into the aqueous liquid flow from the medicine introduction part reaches the bubble generation part is 1 second or less. The bubble generating device according to claim 8 or 9, characterized in that. An ozone water generating method for generating ozone water by introducing ozone gas into water and dissolving and dispersing ozone in water,
The ozone water generation method characterized by producing | generating ozone water using the bubble generation method or bubble generation apparatus as described in any one of Claims 1-10.