JP2010131243A - Biological information measuring apparatus - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an biological information measuring apparatus which can accurately and in detail measure a status of the inside of a living body using biological information accompanying the metabolism of the living body by non-invasion and can be easily mounted. <P>SOLUTION: In a biological information measuring apparatus 1 which has a light-emitting section 2, which has at least two light sources and outgoes to the inside of a living body near infrared light having a different specified wavelength by making the light source emit light based on a predetermined driving signal, a light detection section 3 which detects by light-intercepting the near infrared light, which is outgone from the light-emitting section 2 and spreads over the inside of the living body, and outputs an electrical biological information signal relevant to the metabolism of the living body according to the volume of the detected near infrared light, and a control section 9 which controls the actuation of the light-emitting section 2 and the light detection section 3 in a generalization way, a light-emitting detector 10 which is formed of at least a pair of the light-emitting section 2 and the light detection section 3, is provided and the light-emitting section 2 and the light detection section 3 are arranged by maintaining a fixed distance chosen arbitrarily. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

  This invention depends on the wavelength of light that propagates light in the living body according to the density of the living body, water, blood oxygen concentration, oxygen saturation, glucose concentration, blood glucose level, pulse, and other various living body metabolism. The present invention relates to a biological information measuring apparatus including a light emission detector that measures information inside a living body by paying attention to the property of causing different changes.

  In recent years, as a device that can easily and non-invasively measure the inside of a living body, light is emitted from the light source disposed on the surface of the living body to the inside of the living body, and is reflected and scattered and absorbed inside the living body to reach the living body surface again. Devices that measure the information inside the living body by receiving light are actively proposed. For example, Patent Document 1 below discloses a biological information measuring apparatus that emits light using spread spectrum modulation and measures information in the living body by performing spectrum inverse diffusion demodulation on the light propagated inside the living body.

This biological information measuring apparatus includes a light emitting unit that emits near-infrared light that has been subjected to spread spectrum modulation using a pseudo-noise sequence, and an electrical signal corresponding to the received near-infrared light that has been subjected to spread spectrum modulation. And a light detection unit that outputs a detection signal by performing spread demodulation. And according to this biological information measuring device, biological information can be accurately measured in a state where a high S / N ratio is ensured.
JP 2002-248104 A

  By the way, when near-infrared light is used as the light emitted inside the living body as in the conventional living body information measuring device, for example, information representing blood flow changes inside the living body is accurate as the obtained biological information. Is obtained. That is, blood flowing inside the living body has hemoglobin combined with oxygen and hemoglobin not combined with oxygen, and each of these hemoglobins is known to absorb near-infrared light by different absorption speciations. Yes. For this reason, when near-infrared light is emitted inside the living body, after propagating through the inside of the living body according to the ratio of the amount (concentration) of hemoglobin combined with oxygen and the amount of hemoglobin not combined with oxygen (concentration) The amount of received near-infrared light changes. For this reason, the blood flow change in a measurement area | region can be measured by using the biometric information obtained corresponding to the light quantity of the near-infrared light received.

  It is desired that the light emitting part and the light detecting part, which are important parts thereof, be placed on a living body accurately and easily in order to capture the activation activity in the brain.

  The present invention has been made to solve the above-described problems, and its purpose is to be able to accurately and precisely measure the state of the inside of a living body by using living body information accompanying the metabolism of the living body without being invasive. It is providing the biological information measuring device which can be mounted | worn with.

  In order to solve the above-described problems and achieve the object, the present invention is configured as follows.

A feature of the present invention is that the light emitting unit has at least two light sources, emits the light sources based on a predetermined drive signal, and emits near infrared light having different specific wavelengths into the living body, and Receives and detects near-infrared light emitted from the light emitting part and propagated inside the living body, and outputs an electrical biological information signal related to the metabolism of the living body corresponding to the amount of the detected near-infrared light. A biological information measuring device comprising: an output light detection unit; and a control unit that comprehensively controls the operation of the light emission unit and the light detection unit,
A light emission detector composed of at least a pair of the light emission part and the light detection part;
The light emitting part and the light detecting part are arranged with a fixed distance arbitrarily selected.

The light emission detector is
An adhesive part for adhering to a living body;
When mounting a plurality of the light emission detectors adjacent to each other on a living body, at least one alignment portion so that the position can be accurately determined,
The plurality of light emission detectors are detachable.

  In addition, by arranging the alignment unit at a position that is at the activation center of the biological reaction, it is possible to accurately attach the light emission detector to the living body while aligning the alignment unit with the activation position.

  In addition, the arbitrarily selected fixed distance is 3 cm, and the distance between the alignment portions is 3 cm.

Further, the light emitting part is
An adapter detachably attached to the adhesive portion;
A light-emitting holder that is detachably attached to the adapter and has a light source disposed thereon;
A detachable holder cover for covering the light emitting holder is provided.

The light detection unit is
An adapter detachably attached to the adhesive portion;
A light receiving holder that is detachably attached to the adapter, and in which a sensor that outputs an electrical biological information signal related to the metabolism of the living body corresponding to the amount of near-infrared light detected by receiving light is disposed,
A detachable holder cover for covering the light receiving holder is provided.

With the above configuration, the present invention has the following effects.

  According to the present invention, when a plurality of light emitting units and light detection units are arranged on a living body, it can be accurately and easily adjusted to the activation center of the living body.

Hereinafter, embodiments of the biological information measuring device of the present invention will be described. The embodiment of the present invention shows the most preferable mode of the present invention, and the present invention is not limited to this.
[First Embodiment]
The configuration of the first embodiment of the present invention will be described below with reference to the drawings. 1A and 1B show a biological information measuring apparatus according to a first embodiment. FIG. 1A is a plan view, FIG. 1B is a cross-sectional view, and FIG. 1C is a side view.

  The biological information measuring apparatus 1 according to this embodiment includes a light emission detector 10 configured by at least a pair of a light emission unit 2 and a light detection unit 3.

  This light emission detector 10 is detachably attached to the adhesive part 4 for allowing the light emission part 2 and the light detection part 3 to adhere to the living body S. The adhesive portion 4 is formed in a sheet shape with a soft material such as rubber or resin, and may be provided with an adhesive on the mounting surface 4a, or may be used after being applied with an adhesive.

  The adhesive part 4 has at least one or more positioning parts 5 and 6 so that the position can be accurately determined when a plurality of light emission detectors are attached to a living body adjacent to each other. A plurality of light emission detectors 10 can be attached and detached by the units 5 and 6.

  In this embodiment, the adhesive part 4 is formed in a rectangular sheet shape, the long side length is D1, and the short side length is D2. The alignment part 5 formed on one side of the long side is convex, and the alignment part 6 formed on the other side of the long side is concave. The alignment part 5 and the alignment part 6 are accurate. It has a shape that engages.

  The light emitting unit 2 has at least two light sources, and emits near-infrared light having different specific wavelengths by emitting light from the light sources based on a predetermined drive signal. The light detection unit 3 receives and detects near-infrared light emitted from the light emission unit 2 and propagated inside the living body, and relates to metabolism of the living body S corresponding to the detected amount of near-infrared light. An electrical biological information signal is output.

  The biological information measuring apparatus 1 includes a control unit 9, which comprehensively controls the operations of the light emitting unit 2 and the light detection unit 3, and that uses a biological information signal obtained from the light detection unit 3 as a biological information. Measure internal information.

  The light emission part 2 and the light detection part 3 of the light emission detector 10 are arranged while maintaining an arbitrarily selected fixed distance. In this embodiment, as shown in FIG. 2, the arbitrarily selected fixed distance D11 between the light emitting section 2 and the light detecting section 3 is 3 cm, and the distance D22 between the alignment sections 5 and 6 is 3 cm.

  Next, a use state of the first embodiment of the present invention will be described with reference to the drawings. 3 is a diagram for explaining the detection state, FIG. 4 is a diagram for explaining the alignment, and FIG. 5 is a diagram showing the alignment state.

  The light emission detector 10 is attached to the living body S by the adhesive portion 4 as shown in FIG. In the living body S, particularly in the head of a human adult, when the distance from the light emitting unit 2 to the light detecting unit 3 on the living body surface is 3 cm, the center of the straight line position connecting the light emitting unit 2 and the light detecting unit 3 It is widely known that an activation phenomenon associated with a biological phenomenon of D3 can be captured deeply from a nearby biological surface per 2 cm. It is also well known that the distance D3 is about 2.5 to 2.6 cm for newborn babies.

  Near-infrared light having a different specific wavelength is emitted from the light emitting unit 2 into the living body, and the near-infrared light passes through the activation center O of the site of interest of the biological reaction. The near-infrared light that has been emitted and propagated inside the living body is received and detected, and an electrical biological information signal related to the metabolism of the living body S is output in response to the detected amount of near-infrared light.

  For example, as shown in FIG. 4, when the first light emission detector 10 is mounted on the living body S, the center of the alignment unit 5 or the alignment unit 6 is to be measured. The adhesive part 4 is brought into close contact with the living body S by setting the center position X1 at an arbitrary position of the activation place. As a result, the position of the first light output detector 10 on the living body S is determined.

  Next, as shown in FIG. 5, the alignment unit 5 or the alignment unit 6 and the alignment unit 5 or the alignment unit 6 of the second light emission detector 10 are arranged in close contact with each other, so that a plurality of alignment units 5 or the alignment unit 6 are arranged. The position of the light emission detector 10 on the living body S is accurately determined.

In this way, by arranging the alignment unit 5 or the alignment unit 6 at a position that comes to the activation center O of the biological reaction, the light emission detector 10 while adjusting the alignment unit 5 or the alignment unit 6 to the activation position. Can be accurately attached to the living body S.
[Second Embodiment]
The configuration of the second embodiment of the present invention will be described below with reference to the drawings. FIG. 6 is a plan view showing a biological information measuring apparatus according to the second embodiment.

  In this embodiment, the same configurations as those of the first embodiment are denoted by the same reference numerals and description thereof is omitted. The light emission detector 10 of this embodiment has alignment portions 7 and 8 so that the position can be accurately determined when a plurality of light emission detectors are mounted on the living body S adjacent to the adhesive portion 4. The plurality of light emission detectors 4 can be attached and detached by the alignment portions 7 and 8. The alignment portion 7 formed on one side of the short side is convex, and the alignment portion 8 formed on the other side of the short side is concave. The alignment portion 7 and the alignment portion 8 are accurate. It has a shape that engages.

  Next, a use state of the second embodiment of the present invention will be described with reference to the drawings. FIG. 7 is a diagram showing an alignment state. In this embodiment, it goes without saying that the position can be determined freely in the two-dimensional direction by adding the alignment sections 7 and 8 to the light emission detector 10.

In addition, although the shape of the alignment part is shown as a semicircular shape in the first embodiment and the second embodiment, it is not limited to this, and may be a square, a rectangle, a triangle, or the like.
[Forms of the light emitting unit 2 and the light detecting unit 3]
Next, the form of the light emission part 2 and the light detection part 3 is demonstrated about FIG. 8 thru | or FIG. 8 is a diagram showing an adapter 20 that is used in common for the light emitting unit 2 and the light detecting unit 3, FIG. 9 is a diagram showing a light emitting holder 30 used for the light emitting unit 2, and FIG. 10 is used for the light detecting unit 3. FIG. 11 is a diagram showing a holder cover 50 used in common for the light emitting unit 2 and the light detecting unit 3.

  First, the configuration of the adapter 20 will be described. As shown in FIG. 8, a cylindrical part is integrally formed of resin and attached to the adhesive part 4, and a collar that contacts the surface of the adhesive part 4 when attached. And a support portion 23 provided on the collar portion 22. The attachment portion 21 has a circular shape that can be attached to the adhesive portion 4, and the length thereof is shorter than the thickness of the adhesive portion 4. The collar portion 22 is formed in a circular shape so as to contact the surface of the adhesive portion 4. The support portion 23 has a cylindrical shape, and an insertion recess 23a and an engagement hole portion 23b are formed in the support portion 23, and is used for engaging and holding the light emitting holder 30 or the light receiving holder 40.

  Next, the structure of the light-emitting holder 30 will be described. As shown in FIG. 9, the light-emitting holder 30 is integrally formed of resin in a cylindrical shape, and has a bottom 31 having a circular opening 31a that transmits light, and a lower 3. It has a protrusion 32 formed at a location, an engagement portion 33 formed at two locations on the top, a plurality of grooves 34 formed on the outer periphery in the axial direction, and a notch opening 35 formed at the upper end.

  A light source is arranged inside the light emitting holder 30, and a drive signal wiring of the light source is taken out from the notch opening 35 and connected to the control unit 6. By inserting the protrusion 32 of the light emitting holder 30 into the insertion recess 23a of the adapter 20 and picking and rotating the groove 34 with a finger, the protrusion 32 enters the engaging hole 23b, and the light emitting holder 30 is engaged with the adapter 20. Held together.

  Next, the structure of the light receiving holder 40 will be described. As shown in FIG. 10, the light receiving holder 40 is integrally formed of a resin in a cylindrical shape and has a bottom 41 having a circular opening 41a that transmits light, and a lower 3. It has a protrusion 42 formed at a location, an engagement portion 43 formed at two locations on the top, a plurality of grooves 44 formed in the axial direction on the outer periphery, and a notch opening 45 formed at the upper end.

  The near-infrared light propagating through the living body is received and detected inside the light receiving holder 40, and an electrical biological information signal related to the metabolism of the living body S is output corresponding to the detected light quantity of the near-infrared light. The sensor for the biological information signal of the sensor is taken out from the cutout opening 45 and connected to the control unit 6. By inserting the protrusion 42 of the light receiving holder 40 into the insertion recess 23a of the other adapter 20 and picking and rotating the groove 44 with a finger, the protrusion 42 enters the engaging hole 23b, and the light receiving holder 40 is moved to another portion. The adapter 20 is engaged and held.

  Next, the structure of the holder cover 50 will be described. As shown in FIG. 11, the holder cover 50 is integrally formed of resin in a cylindrical shape, and includes an insertion portion 51 having a pair of claw portions 51a and a notch opening 51b. And a lid portion 52 that covers the insertion portion 51.

  In order to attach the holder cover 50 to the light emitting holder 30, the insertion part 51 is inserted into the upper part of the light emitting holder 30, the pair of claw parts 51a are engaged with the engaging part 33, and the notch opening 51b is opened by this engagement. 35 is positioned so as to overlap with 35, and the wiring of the driving signal of the light source passes therethrough.

  In order to attach the holder cover 50 to the light receiving holder 40, the insertion part 51 is inserted into the upper part of the light receiving holder 40, the pair of claw parts 51a are engaged with the engaging part 43, and the notch opening 51b is thereby engaged. It is positioned so as to overlap with the cutout opening 45, and the wiring of the biological information signal of the sensor passes therethrough.

  As described above, the light emitting unit 2 includes the adapter 20 that is detachably attached to the adhesive unit 4, the light emitting holder 30 that is detachably attached to the adapter 20, and in which the light source is disposed, and the attachment / detachment that covers the light emitting holder 30. When the light source is exchanged in accordance with the use of the ecological information measuring apparatus 1, the holder cover 50 can be easily detached from the adapter 20 by picking and rotating the light emitting holder 30 with a finger.

  In addition, the light detection unit 3 includes an adapter 20 that is detachably attached to the adhesive unit 4 and a detachable attachment of the living body S corresponding to the amount of near infrared light that is detachably attached to the adapter 20 and received and detected. The light receiving holder 30 is provided with a sensor that outputs an electrical biological information signal related to metabolism, and a detachable holder cover 50 that covers the light receiving holder 30. When exchanging the light source, the light emitting holder 30 can be easily detached from the adapter 20 by picking and rotating the light emitting holder 30 with a finger.

  This invention depends on the wavelength of light that propagates light in the living body according to the density of the living body, water, blood oxygen concentration, oxygen saturation, glucose concentration, blood glucose level, pulse, and other various living body metabolism. It can be applied to a biological information measuring device equipped with a light emission detector that measures information inside the living body by paying attention to the property of causing different changes, and the state inside the living body is accurately and precisely determined using biological information associated with the metabolism of the living body. Can be easily measured and installed easily.

It is a figure showing the living body information measuring device of a 1st embodiment. It is a top view of a light emission detector. It is a figure explaining a detection state. It is a figure explaining alignment. It is a figure which shows the alignment state. It is a figure which shows the biological information measuring device of 2nd Embodiment. It is a figure which shows the alignment state. It is a figure which shows the adapter used in common with a light-projection part and a light detection part. It is a figure which shows the light emission holder used for a light-projection part. It is a figure which shows the light reception holder used for a photon detection part. It is a figure which shows the holder cover used in common with a light-projection part and a light detection part.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Biological information measuring device 2 Light emission part 3 Light detection part 4 Adhesion part 5,6 Positioning part 7,8 Positioning part 9 Control part 10 Light emission detector S Living body 20 Adapter 21 Attachment part 22 Collar part 23 Support part 30 Light emitting holder 31 Bottom portion 32 Protruding portion 33 Engaging portion 34 Groove portion 35 Notch opening 40 Light receiving holder 41 Bottom portion 42 Protruding portion 43 Engaging portion 44 Groove portion 45 Notch opening 50 Holder cover 51 Inserting portion 52 Lid portion

Claims (6)

A light emitting unit that has at least two light sources, emits the light sources based on a predetermined drive signal, and emits near-infrared light having different specific wavelengths into the living body;
Receives and detects near-infrared light emitted from the light emitting unit and propagated inside the living body and detects an electrical biological information signal related to metabolism of the living body corresponding to the amount of the detected near-infrared light. A light detection unit that outputs
A biological information measuring device comprising: a control unit that comprehensively controls the operation of the light emitting unit and the light detecting unit;
A light emission detector composed of at least a pair of the light emission part and the light detection part;
The biological information measuring device, wherein the light emitting unit and the light detecting unit are arranged with a fixed distance arbitrarily selected. The light emission detector is
An adhesive part for adhering to a living body;
When mounting a plurality of the light emission detectors adjacent to each other on a living body, at least one alignment portion so that the position can be accurately determined,
The biological information measuring apparatus, wherein the plurality of light emission detectors are detachable.   By disposing the alignment unit at a position at which the biological reaction is activated, the light emission detector can be accurately attached to the living body while aligning the alignment unit with the activation position. The biological information measuring device according to claim 2.   The ecological information measuring apparatus according to claim 2, wherein the arbitrarily selected fixed distance is 3 cm, and the distance between the alignment portions is 3 cm. The light emitting part is
An adapter detachably attached to the adhesive portion;
A light-emitting holder that is detachably attached to the adapter and has a light source disposed thereon;
The biological information measuring apparatus according to claim 1, further comprising a detachable holder cover that covers the light emitting holder. The light detection unit is
An adapter detachably attached to the adhesive portion;
A light receiving holder that is detachably attached to the adapter, and in which a sensor that outputs an electrical biological information signal related to the metabolism of the living body corresponding to the amount of near-infrared light detected by receiving light is disposed,
The biological information measuring device according to any one of claims 1 to 4, further comprising a detachable holder cover that covers the light receiving holder.