JP2010116342A - Detergent composition for pet - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a detergent material for pets which improves residual properties of ceramides, thereby exhibits higher detergency, and yet can make the pet's skin healthy in the detergent composition for pets containing ceramides. <P>SOLUTION: The detergent composition for pets includes (A) 0.05-2 mass% ceramides represented by formula (1) and the like, (B) 10-50 mass% nonionic surface active agent, (C) 20-50 mass% at least one alcohol selected from a lower alcohol, an aromatic alcohol, a polyhydric alcohol, and a polyhydric alcohol derivative, (D) 0.1-5 mass% quaternary ammonium type cationic surface active agent, and (E) water. <P>COPYRIGHT: (C)2010,JPO&amp;INPIT

Description

  The present invention relates to a pet cleaning composition containing ceramide or a ceramide-like substance.

  Human and mammalian skin functions as a barrier film that protects against biological, chemical, or physical invasion by microorganisms, chemical substances, ultraviolet rays, etc. from the outside, and prevents loss of essential biological components such as moisture Is running. The stratum corneum having a thickness of about 20 μm located in the outermost layer of the epidermis functions as a barrier film. The stratum corneum forms a strong barrier film by intercellular lipids connecting keratinocytes stacked in a brick shape like mortar. Among the keratin intercellular lipids, ceramide is known to play an important role in constructing a lipid barrier as a key component and keeping the skin soft and fresh (see Non-Patent Documents 1 and 2).

  Because of these characteristics, ceramide has been applied to various cosmetics together with its similar substances, and patent applications have already been filed as shampoos for humans. For example, as a ceramide or a ceramide analog, a racemic mixture in which the ratio of erythro form to threo form is within a certain range (see Patent Document 1), ceramide or glycoceramide, an anionic surfactant, a zwitterionic surfactant And a cationic polymer, a detergent composition that unravels hair and gives good aesthetics and feel (see Patent Document 2), a cationic dispersant that combines ceramide or glycoceramide and a cationic surfactant (Patent Document) 3).

On the other hand, pets such as dogs and cats have long been connected as friends of human beings, but in recent years, as a companion animal, they have become daily living in the same environment as humans. For this reason, there are many cases where the skin condition becomes unhealthy due to house dust or harmful chemical substances. For the purpose of removing such house dust and harmful chemicals, veterinarians recommend washing the whole body, but in practice, the water retention capacity of the stratum corneum is reduced and the dry skin state is reduced. It has also been observed that the symptoms worsen when induced. A detergent composition in which a nonionic surfactant and a specific cationic polymer are combined with an anionic, amphoteric or semipolar surfactant for the purpose of suppressing reduction of the stratum corneum moisture content is disclosed (see Patent Document 4). ) However, for pets whose frequency of cleaning is usually once a month, at most once a week, even if they were washed with such a cleaning agent, satisfactory results could not be obtained. . In view of such circumstances, the present inventors used ceramide or a ceramide-like substance (hereinafter referred to as “ceramides”) applied to human stratum corneum as an anionic or nonionic surfactant, a cationic polymer or an amphoteric substance. A composition that coexists in water with a polymer and certain alcohols shows a high detergency for pets, and suppresses the transpiration of water from the skin after washing, resulting in a healthy pet skin. The whole body cleaning fee for pets which can be made is disclosed (refer patent documents 5 and 6). As a result, the pet has a high cleaning power twice a week and can keep the pet's skin healthy.
French Patent Application Publication No. 2,673,179 JP-A-8-59443 Japanese National Patent Publication No. 6-502660 JP 2004-35524 A JP 2005-289820 A JP 2008-127278 A Downing DT, et al., J. Lipid. Res., 24, 759 (1983) Downing DT, et al., J. Invest. Dermat., 84, 410 (1985)

  The present invention relates to a pet cleaning material that can further improve the persistence of ceramides than before, thereby exhibiting high cleaning power even with a frequency of cleaning once a week, and making pet skin healthy.

  The inventor has developed a ceramide or a ceramide-like substance (hereinafter referred to as “ceramides”) applied to a human stratum corneum, a nonionic surfactant, a cationic surfactant having a specific structure, and a certain amount. It was found that a composition coexisting in water with the alcohols satisfies the above requirements.

That is, the present invention includes the following components (A) to (E):
(A) Ceramides represented by the general formula (1) or (2): 0.05 to 2% by mass

[Wherein, R ¹ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group or a hydrogen atom having 4 to 30 carbon atoms which may be substituted by a hydroxy group, an oxo group or an amino group; Represents a methylene group, a methine group or an oxygen atom, a broken line represents an unsaturated bond when Z is a methine group, Y ¹ represents a hydrogen atom, an acetyl group or a glyceryl group, or an oxo group together with an adjacent oxygen atom Each of Y ² , Y ³ and Y ⁴ independently represents a hydrogen atom, a hydroxy group or an acetoxy group (provided that when Z is a methine group, one of Y ² and Y ³ is a hydrogen atom) The other does not exist, and when —O—Y ¹ is an oxo group, Y ⁴ does not exist), R ² and R ³ each independently represent a hydrogen atom, a hydroxy group, a hydroxymethyl group or an acetoxymethyl group. , R ⁴ is a hydroxy group, A linear, branched or cyclic saturated or unsaturated carbon atom having 5 to 60 carbon atoms which may have an ether bond, ester bond or amide bond in the main chain, which may be substituted by a xo group or amino group A hydrogen group or an alkoxy group, R ⁵ represents a hydrogen atom, or a straight chain having 1 to 30 carbon atoms which may have a substituent selected from a hydroxy group, a hydroxyalkoxy group, an alkoxy group and an acetoxy group, or A branched saturated or unsaturated hydrocarbon group (provided that when R ¹ is a hydrogen atom and Z is an oxygen atom, R ⁵ is a substituent selected from a hydroxy group, a hydroxyalkoxy group, an alkoxy group and an acetoxy group) When R ¹ is a group other than a hydrogen atom, R ⁵ may be a hydrogen atom, a hydroxy group, a hydroxyalkoxy group, an alkoxy group. A hydrocarbon group having 1 to 30 carbon atoms which may have a substituent selected from a silyl group and an acetoxy group). ]

[Wherein R ⁶ represents a linear or branched hydrocarbon group having 1 to 12 carbon atoms which may be substituted by a hydroxyl group and / or an alkoxy group, and R ⁷ represents a linear or branched chain having 1 to 5 carbon atoms. A branched divalent hydrocarbon group is represented, and R ⁸ represents a linear or branched divalent hydrocarbon group having 1 to 22 carbon atoms. ]

(B) Nonionic surfactant: 10 to 50% by mass,
(C) At least one or more alcohols selected from lower alcohols, aromatic alcohols, polyhydric alcohols and polyhydric alcohol derivatives: 20 to 50% by mass,
(D) Cationic surfactant represented by formula (3) or (4): 0.1 to 5% by mass

[In the formula (3), R ¹ represents a linear or branched alkyl group having 8 to 28 carbon atoms, R ² represents a linear or branched alkyl group having 8 to 28 carbon atoms or a hydroxyalkyl group, or Represents a benzyl group, R ³ and R ⁴ represent an alkyl group having 1 to 3 carbon atoms or a hydroxyalkyl group, and X represents a halogen atom or an alkyl sulfate group having 1 to 2 carbon atoms. In the formula (4), R ⁵ represents a linear or branched alkyl group having 8 to 28 carbon atoms, and Y represents a halogen atom. ]
(E) A cleaning composition for pets containing water is provided.

  The pet cleansing composition of the present invention achieves higher ceramide persistence than before, so that the pet can be washed with high detergency even at a frequency of washing once a week, and from the skin after washing. Moisture transpiration can be suppressed, and therefore the pet's skin can be kept healthy even if the burden on the owner is small.

The ceramide and ceramide-like substance of component (A) constituting the pet cleaning composition of the present invention form a layered structure between keratinocytes and can contribute to hydration and adhesion of keratinocytes. It is a sex substance. Among the components (A), in the ceramides represented by the general formula (1), R ¹ in the general formula (1) is a linear or branched chain having 7 to 22 carbon atoms that may be substituted by a hydroxy group. Alternatively, a cyclic saturated or unsaturated hydrocarbon group or a hydrogen atom is preferable. Y ¹ is preferably a hydrogen atom or a glyceryl group. As Y ² , Y ³ and Y ⁴ , 0 to 1 thereof are preferably a hydroxy group, and the remainder is preferably a hydrogen atom. As R ² and R ³ , one is preferably a hydrogen atom or a hydroxymethyl group, and the other is preferably a hydrogen atom.

R ⁴ is a linear, branched or cyclic saturated or unsaturated hydrocarbon group which may be substituted with a hydroxy group or an amino group, or the ω position of the hydrocarbon group, Preferred are those in which a linear, branched or cyclic saturated or unsaturated fatty acid having 8 to 22 carbon atoms which may be substituted by a hydroxy group is an ester bond or an amide bond. As the fatty acid to be bonded, isostearic acid, 12-hydroxystearic acid or linoleic acid is preferable. R ⁵ is preferably a hydrogen atom or a hydrocarbon group having 1 to 8 carbon atoms in which 1 to 3 groups selected from a hydroxy group, a hydroxyalkoxy group and an alkoxy group may be substituted. Here, as a hydroxy alkoxy group and an alkoxy group, a C1-C7 thing is preferable.

  The ceramides represented by the general formula (1) include natural or natural ceramides and derivatives thereof (hereinafter referred to as “natural ceramides”), and ceramide-like substances.

  Specific examples of natural ceramides include ceramides Type 1 to 7 in which sphingosine, dihydrosphingosine, phytosphingosine, or sphingadienin is amidated (for example, J. Lipid Res., 24: 759 (1983) and FIG. 4 of J. Lipid. Res., 35: 2069 (1994).

  Furthermore, these N-alkyl bodies (for example, N-methyl body) are also mentioned. These may be any of natural extracts and synthetic products, and commercially available products can be used.

  In addition, preferred specific examples of the ceramide-like substance contained in the ceramides represented by the general formula (1) include the following.

Of the ceramides of component (A), the diamide compound represented by the general formula (2) is also a ceramide-like substance. R ⁶ in the general formula (2) is a linear or branched alkyl group having 1 to 12 carbon atoms which may be substituted with 1 to 3 groups selected from a hydroxyl group and an alkoxy group having 1 to 6 carbon atoms. Is preferred. Among them, an unsubstituted alkyl group having 1 to 12 carbon atoms, or 1 to 2 hydroxyl groups, one alkoxy group having 1 to 6 carbon atoms, or one hydroxyl group and one alkoxy group having 1 to 6 carbon atoms. A substituted alkyl group having 2 to 12 carbon atoms is more preferred. Specifically, methyl group, ethyl group, propyl group, butyl group, hexyl group, dodecyl group, 2-methylpropyl group, 2-ethylhexyl group, 2-hydroxyethyl group, 9-hydroxynonyl group, 2,3- Dihydroxypropyl group, 2-methoxyethyl group, 2-hydroxy-3-methoxypropyl group, 9-methoxynonyl group and the like are mentioned, among which 2-hydroxyethyl group, methyl group, dodecyl group, 2-methoxyethyl group are preferable.

In the general formula (2), R ⁷ is preferably a linear or branched alkylene group having 2 to 5 carbon atoms, particularly 2 to 3 carbon atoms. Specifically, ethylene group, trimethylene group, tetramethylene group, pentamethylene group, 1-methylethylene group, 2-methylethylene group, 1-methyltrimethylene group, 2-methyltrimethylene group, 1,1-dimethyl Examples thereof include an ethylene group and a 2-ethyltrimethylene group, and among them, an ethylene group and a trimethylene group are preferable.

In the general formula (2), R ⁸ is preferably a linear or branched divalent hydrocarbon group having 2 to 22 carbon atoms, particularly a linear or branched alkylene group having 11 to 22 carbon atoms, and 1 Alkenylene groups having ˜4 double bonds are preferred. Specifically, ethylene group, trimethylene group, tetramethylene group, hexamethylene group, heptamethylene group, octamethylene group, decamethylene group, undecamethylene group, dodecamethylene group, tridecamethylene group, tetradecamethylene group, hexa Decamethylene group, octadecamethylene group, 1-methylethylene group, 2-ethyltrimethylene group, 1-methylheptamethylene group, 2-methylheptamethylene group, 1-butylhexamethylene group, 2-methyl-5-ethyl Heptamethylene group, 2,3,6-trimethylheptamethylene group, 6-ethyldecamethylene group, 7-methyltetradecamethylene group, 7-ethylhexadecamethylene group, 7,12-dimethyloctadecamethylene group, 8, 11-dimethyloctadecamethylene group, 7,10-dimethyl-7-ethyl Sadecamethylene group, 1-octadecylethylene group, ethenylene group, 1-octadecenylethylene group, 7,11-octadecadiylene group, 7-ethenyl-9-hexadecamethylene group, 7,12-dimethyl-7, Examples include 11-octadecadienylene group, 8,11-dimethyl-7,11-octadecadienylene group, and the like. Among these, 7,12-dimethyloctadecamethylene group, 7,12-dimethyl-7,11-octadecadienylene group, octadecamethylene group, undecamethylene group, and tridecamethylene group are particularly preferable.

Particularly preferred ceramides (2) are compounds in which the above-mentioned preferred groups are combined as R ⁶ , R ⁷ and R ⁸ , and specific examples thereof include the following compounds.

  The ceramides represented by the general formula (1) or (2) can be used in combination of two or more as the component (A), and the content thereof is 0 in the pet cleaning composition of the present invention. Although it is 0.05-2 mass%, it is preferable that it is 0.1-1.5 mass% from the point which suppresses the water | moisture content from the skin after washing | cleaning, and the point of skin feel.

  Examples of the nonionic surfactant which is the component (B) constituting the pet cleaning composition of the present invention include sorbitan monooleate, sorbitan monoisostearate, sorbitan monolaurate, sorbitan monopalmitate, sorbitan Sorbitan fatty acid esters such as monostearate, sorbitan sesquioleate, sorbitan trioleate, diglycerol sorbitan penta-2-ethylhexylate, diglycerol sorbitan tetra-2-ethylhexylate; glyceryl monocaprylate, glyceryl monocaprate, mono Glycerin fatty acid esters such as glyceryl stearate, glycerin α, α'-oleic acid pyroglutamate, glyceryl monoisostearate; propylene glycol such as propylene glycol monostearate POE sorbitan fatty acid esters such as hydrogenated castor oil derivatives, glycerin alkyl ether, polyoxyethylene (hereinafter referred to as “POE”) sorbitan monooleate, POE sorbitan monostearate, POE sorbitan tetraoleate; POE sorbite fatty acid esters such as sorbite monolaurate, POE sorbite monooleate, POE sorbite monooleate, POE sorbite monostearate; POE glycerol monostearate, POE glycerol monoisostearate, POE glycerol triisostearate, etc. POE glycerin fatty acid esters; POE fatty acids such as POE monooleate, POE distearate, POE dioleate, ethylene glycol stearate Steal; POE lauryl ether, POE oleyl ether, POE stearyl ether, POE behenyl ether, POE 2-octyldodecyl ether, POE cholestanol ether, and other POE alkyl ethers; POE octyl phenyl ether, POE nonyl phenyl ether, POE dinonyl POE alkylphenyl ethers such as phenyl ether; POE • polyoxypropylene (hereinafter referred to as “POP”) cetyl ether, POE • POP 2-decyltetradecyl ether, POE • POP monobutyl ether, POE • POP hydrogenated lanolin, POE • POE / POP alkyl ethers such as POP glycerin ether; Tetra POE / tetra POP ethylenediamine condensates such as Tetronic; POE castor oil, POE castor oil such as OE hydrogenated castor oil, POE hydrogenated castor oil monoisostearate, POE hydrogenated castor oil triisostearate, POE hydrogenated castor oil monopyroglutamic acid monoisostearic acid, POE hydrogenated castor oil maleic acid, etc. Derivatives; POE beeswax lanolin derivatives such as POE sorbite beeswax; Alkanolamides such as coconut oil fatty acid diethanolamide, lauric acid monoethanolamide, fatty acid isopropanolamide; alkyl glucosides such as octyl glucoside, dodecyl glucoside, tetradecyl glucoside, hexadecyl glucoside POE propylene glycol fatty acid ester, POE alkylamine, POE fatty acid amide, sucrose fatty acid ester, POE nonylphenylformer Dehydrogenase condensates, alkyl ethoxy dimethylamine oxide, mention may be made of trioleyl phosphate. Of these nonionic surfactants, alkyl glucosides are preferred from the viewpoint of foamability.

  These nonionic surfactants can be used in combination of two or more as the component (B), and the content thereof is 10 to 50% by mass in the pet cleaning composition of the present invention. It is preferable that it is ˜40% by mass from the viewpoint of detergency, the component (A) is left on the skin, and the amount of moisture transpiration from the skin is effectively suppressed.

  The ratio of the ceramides of component (A) to the nonionic surfactant of component (B) has sufficient detergency and optimizes the residual amount of component (A) on the skin ( A) / (B) = 1/200 to 1/10, and particularly preferably a mass ratio of 1/167 to 1/20.

  Among the components (C) constituting the pet cleaning composition of the present invention, the lower alcohol is a linear or branched alcohol having 2 to 5 carbon atoms, specifically, ethanol, n-propyl alcohol, isopropyl alcohol. , N-butyl alcohol and the like. Examples of the aromatic alcohol include benzyl alcohol, 2-benzyloxyethanol, phenoxyethanol and the like. Examples of polyhydric alcohols or derivatives thereof include ethylene glycol, propylene glycol, trimethylene glycol, isoprene glycol, 1,2-butylene glycol, 1,3-butylene glycol, tetramethylene glycol, 2,3-butylene glycol, and pentamethylene glycol. Divalent alcohols such as 2-butene-1,4-diol, hexylene glycol and octylene glycol; trivalent alcohols such as glycerin, trimethylolpropane and 1,2,6-hexanetriol; and pentaerythritol Tetravalent alcohol; diethylene glycol, dipropylene glycol, triethylene glycol, polypropylene glycol, tetraethylene glycol, diglycerin, polyethylene glycol, triglycerin, tetra Polyhydric alcohol polymers such as lysine and polyglycerin; ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, ethylene glycol monophenyl ether, ethylene glycol monohexyl ether, ethylene glycol mono 2-methylhexyl ether, ethylene Ethylene glycol ethers such as glycol isoamyl ether, ethylene glycol benzyl ether, ethylene glycol isopropyl ether, ethylene glycol dimethyl ether, ethylene glycol diethyl ether, ethylene glycol dibutyl ether; diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol monobutyl ether , Ethylene glycol polymer alkyl ethers such as diethylene glycol dimethyl ether, diethylene glycol diethyl ether, diethylene glycol butyl ether, diethylene glycol methyl ethyl ether, triethylene glycol monomethyl ether, triethylene glycol monoethyl ether; propylene glycol monomethyl ether, propylene glycol monoethyl ether, propylene Propylene glycol alkyl ethers such as glycol monobutyl ether and propylene glycol isopropyl ether; dipropylene glycol alkyl ethers such as dipropylene glycol methyl ether, dipropylene glycol ethyl ether and dipropylene glycol butyl ether; ethylene glycol Monomethyl ether acetate, ethylene glycol monoethyl ether acetate, ethylene glycol monobutyl ether acetate, ethylene glycol monophenyl ether acetate, diethylene glycol monoethyl ether acetate, diethylene glycol monobutyl ether acetate, propylene glycol monomethyl ether acetate, propylene glycol monoethyl ether acetate, propylene glycol Dihydric alcohol ether esters such as monopropyl ether acetate and propylene glycol monophenyl ether acetate; Glycerin monoalkyl (or alkenyl) ethers such as xyl alcohol, ceralkyl alcohol and batyl alcohol; ethylene glycol diadipate and ethylene glycol Dihydric alcohol diesters such as aldisuccinate; sugars such as xylitol, sorbitol, maltitol, maltotriose, mannitol, sucrose, erythritol, glucose, fructose, starch-degrading sugar, maltose, xylitolose, amylolytic sugar-reducing alcohol, or Sugar alcohols; glycolide, tetrahydrofurfuryl alcohol and the like.

  Among these alcohols, ethanol is used as the lower alcohol, benzyl alcohol is used as the aromatic alcohol, glycerol and 1,3-butylene glycol are used as the polyhydric alcohol, and an alkyl ether of an ethylene glycol polymer is used as the polyhydric alcohol derivative. Are preferable from the viewpoint of storage stability.

  Two or more of these alcohols can be used in combination, and the content thereof is 20 to 50% by mass in the pet cleaning composition of the present invention, but it is 25 to 40% by mass. In terms of detergency, the component (A) is uniformly dispersed to improve the finish of the coat, and the component (A) is left on the skin, effectively suppressing the amount of moisture transpiration from the skin. It is preferable from the point.

  Examples of the cationic surfactant having a specific structure, which is the component (D) constituting the pet cleaning composition of the present invention, include those represented by general formulas (3) and (4).

[In the formula (3), R ¹ represents a linear or branched alkyl group having 8 to 28 carbon atoms, R ² represents a linear or branched alkyl group having 8 to 28 carbon atoms or a hydroxyalkyl group, or Represents a benzyl group, R ³ and R ⁴ represent an alkyl group having 1 to 3 carbon atoms or a hydroxyalkyl group, and X represents a halogen atom or an alkyl sulfate group having 1 to 2 carbon atoms. In the formula (4), R ⁵ represents a linear or branched alkyl group having 8 to 28 carbon atoms, and Y represents a halogen atom. ]

  Specifically, dialkyldimethylammonium chloride, dicetyldimethylammonium chloride, distearyldimethylammonium chloride, dicocoyldimethylammonium chloride, myristyldimethylbenzylammonium chloride, stearyldimethylbenzylammonium chloride, laurylpyridinium chloride, cetylpyridinium chloride, bromide Examples include cetylpyridinium and benzalkonium chloride, but distearyldimethylammonium chloride, dialkyldimethylammonium chloride, cetylpyridinium bromide, and benzalkonium chloride are preferred. It is more preferable.

  One or more kinds of the cationic surfactants of the component (D) can be used, and 0.1 to 5% by mass, particularly 0.1 to 3% by mass of the total composition is incorporated into the component (A ) Is improved from the standpoint of skin feel. The ratio of the ceramide of component (A) to the cationic surfactant of component (D) is such that the amount of component (A) remaining on the skin is optimized, and (A) / (D) = 1/4 to 1/1, and particularly preferably 1/3 to 2/3. The ratio of the nonionic surfactant of component (B) to the cationic surfactant of component (D) is determined from the point of balance between the amount of the component (A) remaining on the skin and the detergency. / (D) = 50/1 to 5/1, particularly 40/1 to 10/1. Furthermore, the ratio of the alcohol of component (C) to the cationic surfactant of component (D) is (C) / (D) = 50 / 1-5 from the viewpoint of the persistence of component (A). / 1, and preferably a mass ratio of 40/1 to 10/1.

  As the water of the component (E) constituting the pet cleaning composition of the present invention, water purified by a known method can be used. From the viewpoint of the stability of the composition, the water content is preferably 20 to 80% by mass, particularly preferably 30 to 60% by mass, in the pet cleaning composition of the present invention.

  The pet cleaning composition of the present invention preferably contains 0.1 to 5% by mass of polyether-modified silicone as the component (F), which further improves the persistence of the component (A) on the skin. Specific examples of the polyether-modified silicone include dimethylpolysiloxane modified with polyethylene glycol, dimethylpolysiloxane modified with polypropylene glycol, dimethylpolysiloxane partially modified with polypropylene glycol / polyethylene glycol block copolymer, or the following formula: Examples include polyoxyalkylene-modified organopolysiloxanes represented by (5) to (7).

In the above formulas (5) to (7), R is a methyl group or a part thereof is a phenyl group, R ′ is hydrogen or an alkyl group having 1 to 12 carbon atoms, q is 1 to 5, p is a number of 2 to 3, x, m, and n are average numbers, the polyoxyalkylene-modified organopolysiloxane contains 2 to 90% by mass of polyoxyalkylene groups in the molecule, and the viscosity of the polyoxyalkylene-modified organopolysiloxane is 25 ° C. The numerical value is expressed as 5 to 5000 mm ² / s. Examples of commercially available products include KF-6011, KF-6012, KF-615A manufactured by Shin-Etsu Chemical Co., Ltd., SH3771M and SH3775M manufactured by Toray Dow Corning, and L-7002 manufactured by Nippon Unica.

  Two or more kinds of the above-mentioned polyether-modified silicones can be used in combination, and the content thereof is 0.1 to 5% by mass in the pet cleaning composition of the present invention. The content of 3% by mass is preferable from the standpoint of skin feel while allowing the component (A) to remain sufficiently on the skin even at sites with little hair.

  In addition to the above components (A) to (F), the pet cleaning composition of the present invention includes other components used in ordinary cleaning agents, such as powder components, liquid fats and oils, solid fats and oils, waxes, Hydrocarbons, higher alcohols, esters, silicones other than component (F), amphoteric surfactants, cationic polymers, amphoteric polymers, anionic polymers, humectants, water-soluble polymer compounds, thickeners, coating agents , UV absorbers, sequestering agents, sugars, amino acids, organic amines, synthetic resin emulsions, pH adjusters, skin nutrients, vitamins, antioxidants, antioxidant aids, fragrances, etc. as required Can be appropriately blended.

  The pet cleaning composition of the present invention can be used for pets in the same manner as ordinary shampoos. Washing a pet with this detergent composition can wash the pet with high cleaning power even at a frequency of once a week, and can suppress the transpiration of moisture from the skin after washing, and therefore the burden on the owner. Even if there is little, pet's skin can be kept healthy.

Examples 1-4 and Comparative Examples 1-4
A pet cleaning composition containing the components shown in Table 1 was prepared, and the following evaluation was performed. The results are shown in Table 1.

〔Evaluation methods〕
(1) Measurement of residual amount of ceramides The whole body of a beagle is washed in the same manner as a normal shampoo in Examples 1 to 4 and Comparative Examples 1 to 4 shown in Table 1. After drying, the fur of the shank is shaved to 2 cm × 2 cm, and the shaved portion is extracted with acetone / ether (2/1) for 15 seconds × 3 times. The solvent is removed with dry nitrogen gas and dissolved in 1 mL of methanol. Residual bis (methoxypropylamide) octane is quantified by liquid chromatography from this ethanol solution, and the quantified value is converted per 1 cm ² of skin.

(2) Evaluation of skin symptoms 25 dogs suffering from atopic dermatitis were divided into 5 groups of 5 dogs, each of Examples 1-4 and Comparative Examples 1-4, once a week for 3 months each. After washing at a frequency, the effect of improving “itchiness”, “dandruff”, “dryness of skin” and “erythema” at the skin after 3 months was compared with that before the start of the test. The evaluation criteria are as follows.

-Itching: The itch scale of 11 stages (0: not itched at all, 10: constantly scratching) was handed to the owner before and after the start of the test, and the degree of itching of the dog was evaluated. Table 2 shows the results of determination according to the following criteria from the average value of the itch change before and after the test.

◎: Improvement of itch on average exceeds 3 ○: Improvement of itch on average exceeding 2 and below 3 △: Improvement on average of itch exceeding 0 and below 2 ×: Itching is unchanged or deteriorated on average

-Dandruff, dryness, erythema: The specialist evaluated in 5 stages (1: No symptoms ~ 5: Strong symptoms) before and after the start of the test. Table 2 shows the results of determination according to the following criteria from the average value of symptom change before and after the test.

◎: Improvement of symptom exceeding 2 on average ○: Improvement of symptom on average exceeding 1 and 2 or less △: Improvement of symptom on average exceeding 0 and 1 ×: Symptom is unchanged or worsened on average

  In Examples 1 to 4, by using for 3 months, remarkable improvement in “itchiness”, “dandruff”, “dryness of skin” and “erythema” was observed even with a frequency of washing once a week. In Comparative Example 1, a remarkable effect was not observed by washing once a week. In Comparative Examples 2 to 4, itching and dandruff worsened with dry skin.

Claims (2)

Next ingredient (A)-(E)
(A) Ceramides represented by the general formula (1) or (2): 0.05 to 2% by mass

[Wherein, R ¹ represents a linear, branched or cyclic saturated or unsaturated hydrocarbon group or a hydrogen atom having 4 to 30 carbon atoms which may be substituted by a hydroxy group, an oxo group or an amino group; Represents a methylene group, a methine group or an oxygen atom, a broken line represents an unsaturated bond when Z is a methine group, Y ¹ represents a hydrogen atom, an acetyl group or a glyceryl group, or an oxo group together with an adjacent oxygen atom Each of Y ² , Y ³ and Y ⁴ independently represents a hydrogen atom, a hydroxy group or an acetoxy group (provided that when Z is a methine group, one of Y ² and Y ³ is a hydrogen atom) The other does not exist, and when —O—Y ¹ is an oxo group, Y ⁴ does not exist), R ² and R ³ each independently represent a hydrogen atom, a hydroxy group, a hydroxymethyl group or an acetoxymethyl group. , R ⁴ is a hydroxy group, A linear, branched or cyclic saturated or unsaturated carbon atom having 5 to 60 carbon atoms which may have an ether bond, ester bond or amide bond in the main chain, which may be substituted by a xo group or amino group A hydrogen group or an alkoxy group, R ⁵ represents a hydrogen atom, or a straight chain having 1 to 30 carbon atoms which may have a substituent selected from a hydroxy group, a hydroxyalkoxy group, an alkoxy group and an acetoxy group, or A branched saturated or unsaturated hydrocarbon group (provided that when R ¹ is a hydrogen atom and Z is an oxygen atom, R ⁵ is a substituent selected from a hydroxy group, a hydroxyalkoxy group, an alkoxy group and an acetoxy group) When R ¹ is a group other than a hydrogen atom, R ⁵ may be a hydrogen atom, a hydroxy group, a hydroxyalkoxy group, an alkoxy group. A hydrocarbon group having 1 to 30 carbon atoms which may have a substituent selected from a silyl group and an acetoxy group). ]

[Wherein R ⁶ represents a linear or branched hydrocarbon group having 1 to 12 carbon atoms which may be substituted by a hydroxyl group and / or an alkoxy group, and R ⁷ represents a linear or branched chain having 1 to 5 carbon atoms. A branched divalent hydrocarbon group is represented, and R ⁸ represents a linear or branched divalent hydrocarbon group having 1 to 22 carbon atoms. ]
(B) Nonionic surfactant: 10 to 50% by mass,
(C) At least one or more alcohols selected from lower alcohols, aromatic alcohols, polyhydric alcohols and polyhydric alcohol derivatives: 20 to 50% by mass,
(D) Cationic surfactant represented by formula (3) or (4): 0.1 to 5% by mass

[In the formula (3), R ¹ represents a linear or branched alkyl group having 8 to 28 carbon atoms, R ² represents a linear or branched alkyl group having 8 to 28 carbon atoms or a hydroxyalkyl group, or Represents a benzyl group, R ³ and R ⁴ represent an alkyl group having 1 to 3 carbon atoms or a hydroxyalkyl group, and X represents a halogen atom or an alkyl sulfate group having 1 to 2 carbon atoms. In the formula (4), R ⁵ represents a linear or branched alkyl group having 8 to 28 carbon atoms, and Y represents a halogen atom. ]
(E) A cleaning composition for pets containing water.   Furthermore, the cleaning composition for pets of Claim 1 which contains polyether modified silicone 0.1-5 mass% as (F) component.