JP2010111582A - リファンピシンを成分とする肝臓癌治療剤 - Google Patents

リファンピシンを成分とする肝臓癌治療剤 Download PDF

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Publication number
JP2010111582A
JP2010111582A JP2007034960A JP2007034960A JP2010111582A JP 2010111582 A JP2010111582 A JP 2010111582A JP 2007034960 A JP2007034960 A JP 2007034960A JP 2007034960 A JP2007034960 A JP 2007034960A JP 2010111582 A JP2010111582 A JP 2010111582A
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JP
Japan
Prior art keywords
cancer
rifampicin
liver
therapeutic agent
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2007034960A
Other languages
English (en)
Japanese (ja)
Inventor
Masayoshi Shichiri
眞義 七里
Yutaka Kono
裕 河野
Takeshi Hara
剛 原
Hiroshi Makino
弘 牧野
Yoshikazu Hirai
美和 平井
Takanobu Masuda
尊信 増田
Masanobu Sugimoto
正信 杉本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tokyo Medical and Dental University NUC
Genecare Research Institute Co Ltd
Original Assignee
Tokyo Medical and Dental University NUC
Genecare Research Institute Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tokyo Medical and Dental University NUC, Genecare Research Institute Co Ltd filed Critical Tokyo Medical and Dental University NUC
Priority to JP2007034960A priority Critical patent/JP2010111582A/ja
Priority to PCT/JP2008/052443 priority patent/WO2008099883A1/ja
Priority to CN2012102751684A priority patent/CN102793702A/zh
Priority to CNA200880005174XA priority patent/CN101610771A/zh
Publication of JP2010111582A publication Critical patent/JP2010111582A/ja
Pending legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08Bridged systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP2007034960A 2007-02-15 2007-02-15 リファンピシンを成分とする肝臓癌治療剤 Pending JP2010111582A (ja)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2007034960A JP2010111582A (ja) 2007-02-15 2007-02-15 リファンピシンを成分とする肝臓癌治療剤
PCT/JP2008/052443 WO2008099883A1 (ja) 2007-02-15 2008-02-14 肝臓癌治療剤
CN2012102751684A CN102793702A (zh) 2007-02-15 2008-02-14 肝癌治疗剂
CNA200880005174XA CN101610771A (zh) 2007-02-15 2008-02-14 肝癌治疗剂

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2007034960A JP2010111582A (ja) 2007-02-15 2007-02-15 リファンピシンを成分とする肝臓癌治療剤

Publications (1)

Publication Number Publication Date
JP2010111582A true JP2010111582A (ja) 2010-05-20

Family

ID=39690110

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2007034960A Pending JP2010111582A (ja) 2007-02-15 2007-02-15 リファンピシンを成分とする肝臓癌治療剤

Country Status (3)

Country Link
JP (1) JP2010111582A (zh)
CN (2) CN102793702A (zh)
WO (1) WO2008099883A1 (zh)

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4393098B2 (ja) * 2002-06-21 2010-01-06 独立行政法人科学技術振興機構 アンサマイシン系抗生物質の新規用途及び新規血管新生抑制物質のスクリーニング方法

Also Published As

Publication number Publication date
WO2008099883A1 (ja) 2008-08-21
CN101610771A (zh) 2009-12-23
CN102793702A (zh) 2012-11-28

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