JP2009545593A5 - - Google Patents
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- Publication number
- JP2009545593A5 JP2009545593A5 JP2009522831A JP2009522831A JP2009545593A5 JP 2009545593 A5 JP2009545593 A5 JP 2009545593A5 JP 2009522831 A JP2009522831 A JP 2009522831A JP 2009522831 A JP2009522831 A JP 2009522831A JP 2009545593 A5 JP2009545593 A5 JP 2009545593A5
- Authority
- JP
- Japan
- Prior art keywords
- paroxetine
- pharmaceutical composition
- use according
- hormonal changes
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- AHOUBRCZNHFOSL-UHFFFAOYSA-N Paroxetine hydrochloride Natural products C1=CC(F)=CC=C1C1C(COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-UHFFFAOYSA-N 0.000 claims 22
- AHOUBRCZNHFOSL-YOEHRIQHSA-N (+)-Casbol Chemical compound C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 AHOUBRCZNHFOSL-YOEHRIQHSA-N 0.000 claims 18
- 229960002296 paroxetine Drugs 0.000 claims 18
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 230000003054 hormonal effect Effects 0.000 claims 8
- 230000004064 dysfunction Effects 0.000 claims 6
- 150000003839 salts Chemical class 0.000 claims 6
- 239000000203 mixture Substances 0.000 claims 5
- 206010060800 Hot flush Diseases 0.000 claims 4
- 230000009245 menopause Effects 0.000 claims 4
- 230000001331 thermoregulatory effect Effects 0.000 claims 4
- SHIJTGJXUHTGGZ-RVXRQPKJSA-N (3s,4r)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidin-1-ium;methanesulfonate Chemical compound CS(O)(=O)=O.C1=CC(F)=CC=C1[C@H]1[C@H](COC=2C=C3OCOC3=CC=2)CNCC1 SHIJTGJXUHTGGZ-RVXRQPKJSA-N 0.000 claims 2
- 208000033830 Hot Flashes Diseases 0.000 claims 2
- 230000036760 body temperature Effects 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000012458 free base Substances 0.000 claims 2
- 229940088597 hormone Drugs 0.000 claims 2
- 239000005556 hormone Substances 0.000 claims 2
- 206010029410 night sweats Diseases 0.000 claims 2
- 230000036565 night sweats Effects 0.000 claims 2
- 229960005183 paroxetine hydrochloride Drugs 0.000 claims 2
- 229960002567 paroxetine mesylate Drugs 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/499,586 | 2006-08-04 | ||
| US11/499,586 US20080033050A1 (en) | 2006-08-04 | 2006-08-04 | Method of treating thermoregulatory disfunction with paroxetine |
| PCT/US2007/017062 WO2008019010A2 (en) | 2006-08-04 | 2007-07-31 | Method of treating thermoregulatory disfunction with paroxetine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014021171A Division JP5895009B2 (ja) | 2006-08-04 | 2014-02-06 | パロキセチンによる体温調節機能障害の治療方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009545593A JP2009545593A (ja) | 2009-12-24 |
| JP2009545593A5 true JP2009545593A5 (cg-RX-API-DMAC7.html) | 2010-09-16 |
| JP5846717B2 JP5846717B2 (ja) | 2016-01-20 |
Family
ID=39030027
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009522831A Expired - Fee Related JP5846717B2 (ja) | 2006-08-04 | 2007-07-31 | パロキセチンによる体温調節機能障害の治療方法 |
| JP2014021171A Expired - Fee Related JP5895009B2 (ja) | 2006-08-04 | 2014-02-06 | パロキセチンによる体温調節機能障害の治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014021171A Expired - Fee Related JP5895009B2 (ja) | 2006-08-04 | 2014-02-06 | パロキセチンによる体温調節機能障害の治療方法 |
Country Status (27)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080033050A1 (en) | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
| US9211290B2 (en) * | 2012-12-31 | 2015-12-15 | Noven Therapeutics, Llc | Solid dispersions of amorphous paroxetine mesylate |
| SG11201708162UA (en) * | 2015-04-07 | 2017-11-29 | Meiji Co Ltd | Hot flash-suppressing agent |
| KR102817311B1 (ko) | 2016-09-29 | 2025-06-09 | (주)아모레퍼시픽 | 젖산을 유효성분으로 포함하는 열성홍조 개선용 건강식품 조성물 |
Family Cites Families (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| GB8520154D0 (en) * | 1985-08-10 | 1985-09-18 | Beecham Group Plc | Chemical process |
| DE3688827T2 (de) * | 1985-10-25 | 1994-03-31 | Beecham Group Plc | Piperidinderivat, seine Herstellung und seine Verwendung als Arzneimittel. |
| GB8714707D0 (en) * | 1987-06-23 | 1987-07-29 | Beecham Group Plc | Chemical process |
| GB9325644D0 (en) * | 1993-12-15 | 1994-02-16 | Smithkline Beecham Plc | Novel formulation |
| US5470846A (en) * | 1994-01-14 | 1995-11-28 | Sandyk; Reuven | Treatment of neurological and mental disorders |
| JPH0837567A (ja) | 1994-07-26 | 1996-02-06 | Olympus Optical Co Ltd | 情報記録媒体及び情報再生装置 |
| US5856493A (en) * | 1995-02-06 | 1999-01-05 | Smithkline Beecham Corporation | Process for making novel form of paroxeting hydrochloride anhydrate |
| SE9501567D0 (sv) * | 1995-04-27 | 1995-04-27 | Astra Ab | A new combination |
| US6548084B2 (en) * | 1995-07-20 | 2003-04-15 | Smithkline Beecham Plc | Controlled release compositions |
| JP3882224B2 (ja) * | 1996-05-31 | 2007-02-14 | 旭硝子株式会社 | パロキセチンの製造方法 |
| US5672612A (en) * | 1996-09-09 | 1997-09-30 | Pentech Pharmaceuticals, Inc. | Amorphous paroxetine composition |
| US6638948B1 (en) | 1996-09-09 | 2003-10-28 | Pentech Pharmaceuticals, Inc. | Amorphous paroxetine composition |
| CA2193939C (en) * | 1996-12-24 | 2002-02-12 | K.S. Keshava Murthy | Useful form of anhydrous paroxetine hydrochloride |
| GB9700690D0 (en) * | 1997-01-15 | 1997-03-05 | Smithkline Beecham Plc | Novel process |
| GB9710004D0 (en) * | 1997-05-17 | 1997-07-09 | Knoll Ag | Chemical process |
| US5910319A (en) * | 1997-05-29 | 1999-06-08 | Eli Lilly And Company | Fluoxetine enteric pellets and methods for their preparation and use |
| JP2002514222A (ja) * | 1997-05-29 | 2002-05-14 | スミスクライン・ビーチャム・コーポレイション | 新規方法 |
| SK283394B6 (sk) * | 1997-06-10 | 2003-07-01 | Synthon B. V. | Zlúčeniny 4-fenylpiperidínu a jej farmaceuticky prijateľné soli, spôsob ich prípravy, liečivo s ich obsahom a ich použitie |
| US5955475A (en) * | 1997-06-30 | 1999-09-21 | Endo Pharmaceuticals Inc. | Process for manufacturing paroxetine solid dispersions |
| SE9900190D0 (sv) * | 1999-01-22 | 1999-01-22 | Astra Ab | New compounds |
| SE9702799D0 (sv) * | 1997-07-25 | 1997-07-25 | Astra Ab | New compounds |
| US6133277A (en) * | 1997-12-05 | 2000-10-17 | Janssen Pharmaceutica N.V. | (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties |
| BR9908431A (pt) | 1998-03-02 | 2000-10-31 | Lilly Co Eli | Cloridrato de fluoxetina para diminuição de fogalhos |
| CA2323896A1 (en) | 1998-03-16 | 1999-09-23 | Andrew Simon Craig | Crystalline form of paroxetine |
| US6699882B2 (en) * | 1998-03-24 | 2004-03-02 | Smithkline Beecham P.L.C. | Paroxetine compositions |
| US20030028027A1 (en) * | 1998-04-09 | 2003-02-06 | Smithkline Beecham Plc | Paroxetine maleate |
| JP3796351B2 (ja) * | 1998-04-13 | 2006-07-12 | 住友化学株式会社 | パロキセチン塩酸塩無水和物の乾燥方法 |
| US6168805B1 (en) * | 1998-05-07 | 2001-01-02 | Endo Pharmaceuticals, Inc. | Aqueous process for manufacturing paroxetine solid dispersions |
| CH689805A8 (fr) * | 1998-07-02 | 2000-02-29 | Smithkline Beecham Plc | Méthanesulfonate de paroxétine, procédé pour sa préparation et compositions pharmaceutiques le contenant. |
| ES2138937B1 (es) * | 1998-07-07 | 2000-10-01 | Medichem Sa | Polimorfo de maleato de paroxetina y formulaciones farmaceuticas que lo contienen. |
| ES2159260B1 (es) * | 1999-06-22 | 2002-05-01 | Smithkline Beechan Plc | Nueva composicion de metanosulfonato de paroxetina |
| US6369051B1 (en) * | 2000-07-06 | 2002-04-09 | American Home Products Corporation | Combinations of SSRI and estrogenic agents |
| US6660298B1 (en) * | 2000-07-27 | 2003-12-09 | Pentech Pharmaceuticals, Inc. | Paroxetine tablets and capsules |
| AU2001296084A1 (en) | 2000-08-28 | 2002-03-13 | Synthon B.V. | Paroxetine compositions and processes for making the same |
| US6498184B2 (en) * | 2000-12-05 | 2002-12-24 | Akzo Nobel N.V. | Serotonergic compound for a method of treatment of hot flushes in post-menopausal women |
| JP2004520333A (ja) * | 2001-01-04 | 2004-07-08 | フエルレル インターナショナル，ソシエダッド アノニマ | （±）−トランス−４−ｐ−フルオロフェニル−３−ヒドロキシメチル−１−メチルピペリジンの製造方法。 |
| DE20100529U1 (de) | 2001-01-11 | 2001-05-10 | Synthon Bv | Pharmazeutische Tablette umfassend Paroxetinmesylat |
| NL1017421C2 (nl) * | 2001-02-21 | 2002-01-15 | Synthon Bv | Werkwijze voor het vervaardigen van paroxetine. |
| EP1266659A1 (en) | 2001-06-11 | 2002-12-18 | Pantarhei Bioscience B.V. | Pyridoxal in combination with serotonin re-uptake inhibitor for the treatment of hot flushes |
| US6956121B2 (en) * | 2002-03-01 | 2005-10-18 | Teva Pharmaceutical Industries Ltd. | Preparation of paroxetine involving novel intermediates |
| KR20050049476A (ko) * | 2002-08-14 | 2005-05-25 | 파마시아 앤드 업존 캄파니 엘엘씨 | 홍조를 치료하기 위한 레복세틴의 용도 |
| US20040152710A1 (en) * | 2002-10-15 | 2004-08-05 | Deecher Darlene Coleman | Use of norepinephrine reuptake modulators for preventing and treating vasomotor symptoms |
| ITMI20022344A1 (it) * | 2002-11-05 | 2004-05-06 | Biofarm Srl | Prodotto in pellicola a rapida dissoluzione in acqua, per il trattamento del latte con batteri e/o enzimi. |
| TWI267838B (en) * | 2003-01-03 | 2006-12-01 | Lite On It Corp | Method to detect the type of optical disk |
| US20050130987A1 (en) | 2003-10-14 | 2005-06-16 | Wyeth | Methods of treating vasomotor symptoms |
| JP2008507552A (ja) * | 2004-07-22 | 2008-03-13 | ワイス | 神経系障害および状態の治療方法 |
| JP2008507550A (ja) * | 2004-07-22 | 2008-03-13 | ワイス | 神経系障害及び状態の処置方法 |
| US20060100263A1 (en) * | 2004-11-05 | 2006-05-11 | Anthony Basile | Antipyretic compositions and methods |
| KR100764679B1 (ko) | 2005-07-22 | 2007-10-09 | 익수제약 주식회사 | 파록세틴을 함유하는 경피투여용 패취제 |
| ATE544444T1 (de) * | 2005-10-11 | 2012-02-15 | Yissum Res Dev Co | Zusammensetzungen für die nasale abgabe |
| US20080033050A1 (en) | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
-
2006
- 2006-08-04 US US11/499,586 patent/US20080033050A1/en not_active Abandoned
-
2007
- 2007-07-31 JP JP2009522831A patent/JP5846717B2/ja not_active Expired - Fee Related
- 2007-07-31 EP EP13190594.5A patent/EP2719385B1/en active Active
- 2007-07-31 HU HUE07810919A patent/HUE040481T2/hu unknown
- 2007-07-31 KR KR1020157032729A patent/KR20150132888A/ko not_active Ceased
- 2007-07-31 PT PT13190594T patent/PT2719385T/pt unknown
- 2007-07-31 AU AU2007282065A patent/AU2007282065B2/en not_active Ceased
- 2007-07-31 WO PCT/US2007/017062 patent/WO2008019010A2/en not_active Ceased
- 2007-07-31 PL PL07810919T patent/PL2068881T3/pl unknown
- 2007-07-31 SG SG2011081056A patent/SG176452A1/en unknown
- 2007-07-31 HR HRP20181893TT patent/HRP20181893T1/hr unknown
- 2007-07-31 PT PT07810919T patent/PT2068881T/pt unknown
- 2007-07-31 ES ES07810919T patent/ES2698207T3/es active Active
- 2007-07-31 DK DK13190594.5T patent/DK2719385T3/en active
- 2007-07-31 ES ES13190594T patent/ES2699298T3/es active Active
- 2007-07-31 KR KR1020147020772A patent/KR20140098865A/ko not_active Ceased
- 2007-07-31 KR KR1020097004195A patent/KR20090040453A/ko not_active Ceased
- 2007-07-31 SI SI200732079T patent/SI2719385T1/sl unknown
- 2007-07-31 RS RS20181386A patent/RS58046B1/sr unknown
- 2007-07-31 RS RS20181413A patent/RS57980B1/sr unknown
- 2007-07-31 DK DK07810919.6T patent/DK2068881T3/en active
- 2007-07-31 ME MEP-2009-37A patent/ME00592B/me unknown
- 2007-07-31 PL PL13190594T patent/PL2719385T3/pl unknown
- 2007-07-31 CN CNA2007800289306A patent/CN101505759A/zh active Pending
- 2007-07-31 UA UAA200901871A patent/UA96770C2/uk unknown
- 2007-07-31 NZ NZ574735A patent/NZ574735A/en not_active IP Right Cessation
- 2007-07-31 EP EP07810919.6A patent/EP2068881B1/en active Active
- 2007-07-31 MX MX2009001275A patent/MX2009001275A/es unknown
- 2007-07-31 LT LTEP07810919.6T patent/LT2068881T/lt unknown
- 2007-07-31 CA CA2659577A patent/CA2659577C/en active Active
- 2007-07-31 BR BRPI0715087-3A2A patent/BRPI0715087A2/pt not_active Application Discontinuation
- 2007-07-31 HU HUE13190594A patent/HUE040099T2/hu unknown
- 2007-07-31 SI SI200732071T patent/SI2068881T1/sl unknown
- 2007-07-31 RU RU2009107739/15A patent/RU2478379C2/ru not_active IP Right Cessation
- 2007-07-31 LT LTEP13190594.5T patent/LT2719385T/lt unknown
-
2008
- 2008-12-01 US US12/292,960 patent/US8658663B2/en active Active
-
2009
- 2009-02-02 IL IL196844A patent/IL196844A/en active IP Right Grant
- 2009-02-10 NO NO20090639A patent/NO343176B1/no not_active IP Right Cessation
-
2014
- 2014-01-17 US US14/157,992 patent/US8946251B2/en active Active
- 2014-02-06 JP JP2014021171A patent/JP5895009B2/ja not_active Expired - Fee Related
- 2014-05-13 US US14/276,494 patent/US8859576B2/en active Active
- 2014-12-19 US US14/577,227 patent/US9393237B2/en active Active
-
2016
- 2016-07-15 US US15/211,074 patent/US20170165251A1/en not_active Abandoned
-
2017
- 2017-10-17 US US15/785,769 patent/US20200268733A9/en not_active Abandoned
-
2018
- 2018-11-19 CY CY181101219T patent/CY1120867T1/el unknown
- 2018-11-19 HR HRP20181925TT patent/HRP20181925T1/hr unknown
- 2018-11-23 CY CY181101241T patent/CY1120902T1/el unknown
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