JP2009545519A - 加齢黄斑変性症を治療するための光動力学的療法 - Google Patents
加齢黄斑変性症を治療するための光動力学的療法 Download PDFInfo
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- JP2009545519A JP2009545519A JP2009511610A JP2009511610A JP2009545519A JP 2009545519 A JP2009545519 A JP 2009545519A JP 2009511610 A JP2009511610 A JP 2009511610A JP 2009511610 A JP2009511610 A JP 2009511610A JP 2009545519 A JP2009545519 A JP 2009545519A
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- 206010064930 age-related macular degeneration Diseases 0.000 title claims abstract description 25
- 208000002780 macular degeneration Diseases 0.000 title claims abstract description 11
- 238000002428 photodynamic therapy Methods 0.000 title claims description 16
- 230000003287 optical effect Effects 0.000 claims abstract description 40
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 27
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims abstract description 16
- 229910052760 oxygen Inorganic materials 0.000 claims abstract description 16
- 239000001301 oxygen Substances 0.000 claims abstract description 16
- 238000005259 measurement Methods 0.000 claims abstract 3
- 230000002207 retinal effect Effects 0.000 claims description 30
- 238000003384 imaging method Methods 0.000 claims description 20
- 238000002372 labelling Methods 0.000 claims description 18
- 238000000034 method Methods 0.000 claims description 14
- 230000004044 response Effects 0.000 claims description 10
- 210000001525 retina Anatomy 0.000 claims description 10
- 229940079593 drug Drugs 0.000 claims description 5
- 239000003814 drug Substances 0.000 claims description 5
- 238000004891 communication Methods 0.000 claims description 4
- ZQFGRJWRSLZCSQ-ZSFNYQMMSA-N verteporfin Chemical compound C=1C([C@@]2([C@H](C(=O)OC)C(=CC=C22)C(=O)OC)C)=NC2=CC(C(=C2C=C)C)=NC2=CC(C(=C2CCC(O)=O)C)=NC2=CC2=NC=1C(C)=C2CCC(=O)OC ZQFGRJWRSLZCSQ-ZSFNYQMMSA-N 0.000 claims description 4
- 229960003895 verteporfin Drugs 0.000 claims description 4
- 208000000208 Wet Macular Degeneration Diseases 0.000 description 10
- 230000003044 adaptive effect Effects 0.000 description 10
- 230000005284 excitation Effects 0.000 description 6
- 238000010521 absorption reaction Methods 0.000 description 5
- 238000005286 illumination Methods 0.000 description 5
- 206010025421 Macule Diseases 0.000 description 4
- 230000000996 additive effect Effects 0.000 description 4
- 210000004087 cornea Anatomy 0.000 description 4
- 230000000694 effects Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 210000005166 vasculature Anatomy 0.000 description 3
- 239000000654 additive Substances 0.000 description 2
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- 230000002491 angiogenic effect Effects 0.000 description 2
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- 238000006243 chemical reaction Methods 0.000 description 2
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- 230000010363 phase shift Effects 0.000 description 2
- 230000000649 photocoagulation Effects 0.000 description 2
- 238000010186 staining Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000001356 surgical procedure Methods 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 238000009736 wetting Methods 0.000 description 2
- 208000017442 Retinal disease Diseases 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
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- 239000013043 chemical agent Substances 0.000 description 1
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- 230000003993 interaction Effects 0.000 description 1
- 238000002430 laser surgery Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000003278 mimic effect Effects 0.000 description 1
- 210000001328 optic nerve Anatomy 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00844—Feedback systems
- A61F2009/00848—Feedback systems based on wavefront
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
- A61F2009/00863—Retina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F9/00825—Methods or devices for eye surgery using laser for photodisruption
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Ophthalmology & Optometry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Radiology & Medical Imaging (AREA)
- Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Chemical & Material Sciences (AREA)
- Laser Surgery Devices (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Radiation-Therapy Devices (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/420,414 US20080009922A1 (en) | 2006-05-25 | 2006-05-25 | Photodynamic therapy for treating age-related macular degeneration |
| PCT/IB2007/003151 WO2007138490A2 (en) | 2006-05-25 | 2007-05-22 | Photodynamic therapy for treatng age-related macular degeneration |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009545519A true JP2009545519A (ja) | 2009-12-24 |
| JP2009545519A5 JP2009545519A5 (enExample) | 2010-03-25 |
Family
ID=38779057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009511610A Pending JP2009545519A (ja) | 2006-05-25 | 2007-05-22 | 加齢黄斑変性症を治療するための光動力学的療法 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20080009922A1 (enExample) |
| EP (1) | EP2021967A2 (enExample) |
| JP (1) | JP2009545519A (enExample) |
| WO (1) | WO2007138490A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014042671A (ja) * | 2012-08-27 | 2014-03-13 | Fukuoka Univ | 第二次高調波光を用いた新規コラーゲン線維化評価モデル |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080269730A1 (en) * | 2005-04-14 | 2008-10-30 | Dotson Robert S | Ophthalmic Phototherapy Device and Associated Treatment Method |
| US20130079759A1 (en) * | 2005-04-14 | 2013-03-28 | Robert S. Dotson | Ophthalmic Phototherapy Device and Associated Treatment Method |
| WO2009023774A1 (en) * | 2007-08-15 | 2009-02-19 | The Cleveland Clinic Foundation | Precise disruption of tissue in retinal and preretinal structures |
| US7703923B2 (en) * | 2008-09-05 | 2010-04-27 | Heidelberg Engineering Gmbh | System and method for imaging retinal tissue with tissue generated light |
| RU2408335C1 (ru) * | 2009-11-03 | 2011-01-10 | Государственное образовательное учреждение высшего профессионального образования "Российский государственный медицинский университет Федерального агентства по здравоохранению и социальному развитию" (ГОУ ВПО РГМУ Росздрава) | Способ лечения возрастной макулярной дегенерации сетчатки |
| KR101118146B1 (ko) | 2009-12-04 | 2012-03-12 | 한국표준과학연구원 | 레이저를 이용한 안구 질환 치료 장치 및 레이저를 이용한 안구 질환 진단 장치 |
| EP2583719A1 (en) * | 2011-10-20 | 2013-04-24 | Heidelberg Engineering GmbH | Diagnostic imaging for age-related macular degeneration (AMD) using second harmonic generation (SHG) techniques |
| US20130103015A1 (en) * | 2011-10-21 | 2013-04-25 | Robert Edward Grant | OCT-Guided Femtosecond Laser to Measure a Retinal Surface for Use in Performing an Intra-Retinal Ablation |
| US9629750B2 (en) | 2012-04-18 | 2017-04-25 | Technolas Perfect Vision Gmbh | Surgical laser unit with variable modes of operation |
| US10589120B1 (en) | 2012-12-31 | 2020-03-17 | Gary John Bellinger | High-intensity laser therapy method and apparatus |
| AU2015315113B2 (en) | 2014-09-09 | 2020-03-05 | LumiThera, Inc. | Multi-wavelength phototherapy devices, systems, and methods for the non-invasive treatment of damaged or diseased tissue |
| WO2016090590A1 (en) * | 2014-12-11 | 2016-06-16 | Bayer Healthcare Llc | Treatment of age related macular degeneration with a small active choroidalneovascularizationlesion |
| JP7083821B2 (ja) * | 2016-06-17 | 2022-06-13 | ソルボンヌ・ユニヴェルシテ | 制御された光強度で対象物を照明するための装置および関連する方法 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002517419A (ja) * | 1998-06-12 | 2002-06-18 | フォトゲン インク | 治療薬剤の多光子光活性化のための改善された方法及び装置 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4754328A (en) * | 1984-01-03 | 1988-06-28 | Medical Dynamics, Inc. | Laser endoscope |
| US4638800A (en) * | 1985-02-08 | 1987-01-27 | Research Physics, Inc | Laser beam surgical system |
| US4998930A (en) * | 1988-08-03 | 1991-03-12 | Phototherapeutic Systems | Intracavity laser phototherapy method |
| DE69221806T2 (de) * | 1991-10-10 | 1998-03-26 | Coherent Inc | Vorrichtung zum Abgeben eines defokussierten Laserstrahls mit scharfkantigem Querschnitt |
| US5413555A (en) * | 1993-04-30 | 1995-05-09 | Mcmahan; William H. | Laser delivery system |
| AU5895998A (en) * | 1996-12-04 | 1998-06-29 | Research Foundation Of City College Of New York, The | A system and method for performing selected optical measurements |
| JP2000060893A (ja) * | 1998-08-20 | 2000-02-29 | Kowa Co | 眼科治療装置 |
| US6494878B1 (en) * | 2000-05-12 | 2002-12-17 | Ceramoptec Industries, Inc. | System and method for accurate optical treatment of an eye's fundus |
| US6942655B2 (en) * | 2001-11-13 | 2005-09-13 | Minu, Llc | Method to treat age-related macular degeneration |
| DE10323422B4 (de) * | 2002-08-23 | 2022-05-05 | Carl Zeiss Meditec Ag | Vorrichtung und Verfahren zur Messung eines optischen Durchbruchs in einem Gewebe |
| IL156626A (en) * | 2003-06-24 | 2009-12-24 | Yeda Res & Dev | System for selective cell destruction |
| US7510283B2 (en) * | 2003-11-20 | 2009-03-31 | Heidelberg Engineering Optische Messsysteme Gmbh | High resolution imaging for diagnostic evaluation of the fundus of the human eye |
-
2006
- 2006-05-25 US US11/420,414 patent/US20080009922A1/en not_active Abandoned
-
2007
- 2007-05-22 EP EP07815044A patent/EP2021967A2/en not_active Ceased
- 2007-05-22 WO PCT/IB2007/003151 patent/WO2007138490A2/en not_active Ceased
- 2007-05-22 JP JP2009511610A patent/JP2009545519A/ja active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002517419A (ja) * | 1998-06-12 | 2002-06-18 | フォトゲン インク | 治療薬剤の多光子光活性化のための改善された方法及び装置 |
Non-Patent Citations (2)
| Title |
|---|
| JPN6012019228; KAROTKI, A. et al.: Photochemistry and Photobiology Vol.82, 200603, pp.443-452 * |
| JPN6012019231; SAMKOE, K.S. et al.: Journal of Biomedical Optics Vol.8, No.3, 2003, pp.410-417 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2014042671A (ja) * | 2012-08-27 | 2014-03-13 | Fukuoka Univ | 第二次高調波光を用いた新規コラーゲン線維化評価モデル |
Also Published As
| Publication number | Publication date |
|---|---|
| US20080009922A1 (en) | 2008-01-10 |
| WO2007138490A3 (en) | 2009-10-29 |
| WO2007138490A2 (en) | 2007-12-06 |
| EP2021967A2 (en) | 2009-02-11 |
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