JP2009539353A - Hiv−1クレイドaのコンセンサス配列、抗原及びトランス遺伝子 - Google Patents

Hiv−1クレイドaのコンセンサス配列、抗原及びトランス遺伝子 Download PDF

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JP2009539353A
JP2009539353A JP2009513483A JP2009513483A JP2009539353A JP 2009539353 A JP2009539353 A JP 2009539353A JP 2009513483 A JP2009513483 A JP 2009513483A JP 2009513483 A JP2009513483 A JP 2009513483A JP 2009539353 A JP2009539353 A JP 2009539353A
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hiv
clade
sequence
antigen
consensus
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カルパナ グプタ
ニコラス ジャクソン
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インターナショナル エイズ バクシーン イニシアティブ
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    • C12Q1/703Viruses associated with AIDS
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    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
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    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
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    • C12N2710/10011Adenoviridae
    • C12N2710/10311Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341Use of virus, viral particle or viral elements as a vector
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    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16111Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16311Human Immunodeficiency Virus, HIV concerning HIV regulatory proteins
    • C12N2740/16322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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JP2009513483A 2006-06-02 2007-06-04 Hiv−1クレイドaのコンセンサス配列、抗原及びトランス遺伝子 Withdrawn JP2009539353A (ja)

Applications Claiming Priority (2)

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US81081606P 2006-06-02 2006-06-02
PCT/US2007/070321 WO2007143606A2 (en) 2006-06-02 2007-06-04 Hiv-1 clade a consensus sequences, antigens, and transgenes

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JP2009539353A true JP2009539353A (ja) 2009-11-19
JP2009539353A5 JP2009539353A5 (https=) 2011-07-28

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US (2) US8119144B2 (https=)
EP (2) EP2399602B1 (https=)
JP (1) JP2009539353A (https=)
AU (1) AU2007256717B2 (https=)
CA (1) CA2654324A1 (https=)
DK (2) DK2029168T3 (https=)
ES (2) ES2396915T3 (https=)
WO (1) WO2007143606A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015530410A (ja) * 2012-09-19 2015-10-15 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア B型肝炎ウイルスコアタンパク質および表面抗原タンパク質をコードする核酸分子ならびにそれを含むワクチン

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160256539A1 (en) * 2013-11-14 2016-09-08 The Trustees Of The University Of Pennsylvania HIV-1 ENV DNA Vaccine Plus Protein Boost Delivered by EP Expands B- and T-Cell Response and Neutralizing
KR20240137107A (ko) 2019-07-16 2024-09-19 길리애드 사이언시즈, 인코포레이티드 Hiv 백신, 및 이의 제조 및 사용 방법
US12053517B2 (en) 2021-01-14 2024-08-06 Gilead Sciences, Inc. HIV vaccines and methods of using

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5833975A (en) 1989-03-08 1998-11-10 Virogenetics Corporation Canarypox virus expressing cytokine and/or tumor-associated antigen DNA sequence
IL73534A (en) 1983-11-18 1990-12-23 Riker Laboratories Inc 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds
US5057540A (en) 1987-05-29 1991-10-15 Cambridge Biotech Corporation Saponin adjuvant
US5238944A (en) 1988-12-15 1993-08-24 Riker Laboratories, Inc. Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine
US6780407B1 (en) 1989-03-08 2004-08-24 Aventis Pasteur Pox virus comprising DNA sequences encoding CEA and B7 antigen
US6309647B1 (en) 1999-07-15 2001-10-30 Aventis Pasteur Poxvirus—canine dispemper virus (CDV) or measles virus recombinants and compositions and methods employing the recombinants
US6277558B1 (en) 1990-11-30 2001-08-21 Kansas University Medical Center α-3 chain type IV collagen polynucleotides
US5650398A (en) 1992-07-02 1997-07-22 Cambridge Biotech Corporation Drug delivery enhancement via modified saponins
PT799058E (pt) 1994-12-24 2003-11-28 Univ Cambridge Tech Melhoramentos na funcao endometrica ou com ela relacionados
US6156567A (en) 1996-07-03 2000-12-05 Merial Truncated transcriptionally active cytomegalovirus promoters
US6090393A (en) 1996-07-03 2000-07-18 Merial Recombinant canine adenoviruses, method for making and uses thereof
US6231859B1 (en) 1996-12-02 2001-05-15 Aquila Biopharmaceuticals, Inc. Saponin adjuvant compositions
US20020136722A1 (en) 1997-06-18 2002-09-26 Heath Andrew William Vaccination method
CA2302522C (en) 1997-08-29 2010-08-17 Antigenics Llc Compositions comprising the adjuvant qs-21 and polysorbate or cyclodextrin as excipient
US6693086B1 (en) 1998-06-25 2004-02-17 National Jewish Medical And Research Center Systemic immune activation method using nucleic acid-lipid complexes
US6913922B1 (en) 1999-05-18 2005-07-05 Crucell Holland B.V. Serotype of adenovirus and uses thereof
US6492169B1 (en) 1999-05-18 2002-12-10 Crucell Holland, B.V. Complementing cell lines
AU784679B2 (en) 1999-12-23 2006-05-25 International Aids Vaccine Initiative Improvements in or relating to immune responses to HIV
JP2004507231A (ja) 2000-06-15 2004-03-11 アメリカ合衆国 免疫応答を向上させるための、gm−csfを発現する組換え非−複製性ウィルスおよびその使用
IT1318103B1 (it) 2000-07-03 2003-07-23 Nuovo Pignone Spa Sistema di connessione tra un ugello di bassa pressione ed untransition duct in una turbina a gas
BRPI0414443A (pt) * 2003-09-17 2006-11-21 Univ Duke imunógenos consensuais/ancestrais
WO2005047483A2 (en) * 2003-11-12 2005-05-26 Medical Research Council Renta: an hiv immunogen and uses thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015530410A (ja) * 2012-09-19 2015-10-15 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア B型肝炎ウイルスコアタンパク質および表面抗原タンパク質をコードする核酸分子ならびにそれを含むワクチン
JP2019163286A (ja) * 2012-09-19 2019-09-26 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア B型肝炎ウイルスコアタンパク質および表面抗原タンパク質をコードする核酸分子ならびにそれを含むワクチン
JP7050310B2 (ja) 2012-09-19 2022-04-08 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア B型肝炎ウイルスコアタンパク質および表面抗原タンパク質をコードする核酸分子ならびにそれを含むワクチン
JP2022084800A (ja) * 2012-09-19 2022-06-07 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア B型肝炎ウイルスコアタンパク質および表面抗原タンパク質をコードする核酸分子ならびにそれを含むワクチン
JP7636804B2 (ja) 2012-09-19 2025-02-27 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルバニア B型肝炎ウイルスコアタンパク質および表面抗原タンパク質をコードする核酸分子ならびにそれを含むワクチン

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Publication number Publication date
EP2029168B1 (en) 2012-10-03
AU2007256717B2 (en) 2013-06-20
WO2007143606A2 (en) 2007-12-13
US20080089909A1 (en) 2008-04-17
EP2399602B1 (en) 2014-11-26
EP2029168A2 (en) 2009-03-04
AU2007256717A1 (en) 2007-12-13
CA2654324A1 (en) 2007-12-13
WO2007143606A9 (en) 2008-02-14
EP2399602A1 (en) 2011-12-28
EP2029168A4 (en) 2010-10-27
ES2528951T3 (es) 2015-02-13
US8119144B2 (en) 2012-02-21
DK2029168T3 (da) 2013-01-14
DK2399602T3 (en) 2015-02-23
US8735542B2 (en) 2014-05-27
US20120219577A1 (en) 2012-08-30
WO2007143606A3 (en) 2008-11-13
ES2396915T3 (es) 2013-03-01

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