JP2009537599A - 新規８，１０−ジアザ−ビシクロ［４．３．１］デカン誘導体及びそれらの医学的使用 - Google Patents
新規８，１０−ジアザ−ビシクロ［４．３．１］デカン誘導体及びそれらの医学的使用 Download PDFInfo
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- JP2009537599A JP2009537599A JP2009511493A JP2009511493A JP2009537599A JP 2009537599 A JP2009537599 A JP 2009537599A JP 2009511493 A JP2009511493 A JP 2009511493A JP 2009511493 A JP2009511493 A JP 2009511493A JP 2009537599 A JP2009537599 A JP 2009537599A
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- Prior art keywords
- diaza
- bicyclo
- alkyl
- decane
- pain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Classifications
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80252706P | 2006-05-23 | 2006-05-23 | |
| DKPA200600706 | 2006-05-23 | ||
| PCT/EP2007/054870 WO2007135121A1 (en) | 2006-05-23 | 2007-05-21 | Novel 8,10-diaza-bicyclo[4.3.1]decane derivatives and their medical use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009537599A true JP2009537599A (ja) | 2009-10-29 |
| JP2009537599A5 JP2009537599A5 (cg-RX-API-DMAC7.html) | 2010-04-15 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009511493A Abandoned JP2009537599A (ja) | 2006-05-23 | 2007-05-21 | 新規８，１０−ジアザ−ビシクロ［４．３．１］デカン誘導体及びそれらの医学的使用 |
Country Status (4)
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|---|---|
| US (1) | US7910578B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2029607A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2009537599A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2007135121A1 (cg-RX-API-DMAC7.html) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019500352A (ja) * | 2015-12-10 | 2019-01-10 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI558398B (zh) | 2009-09-22 | 2016-11-21 | 諾華公司 | 菸鹼乙醯膽鹼受體α７活化劑之用途 |
| WO2018226622A1 (en) | 2017-06-05 | 2018-12-13 | Ptc Therapeutics, Inc. | Compounds for treating huntington's disease |
| BR112019027717A2 (pt) | 2017-06-28 | 2020-07-28 | Ptc Therapeutics, Inc. | métodos para tratar a doença de huntington |
| EP3645121B8 (en) | 2017-06-28 | 2025-06-18 | PTC Therapeutics, Inc. | Methods for treating huntington's disease |
| CA3094703A1 (en) | 2018-03-27 | 2019-10-03 | Ptc Therapeutics, Inc. | Compounds for treating huntington's disease |
| CN112805280B (zh) | 2018-06-27 | 2024-12-06 | Ptc医疗公司 | 用于治疗亨廷顿氏病的杂芳基化合物 |
| JP7421507B2 (ja) | 2018-06-27 | 2024-01-24 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病を処置するためのヘテロ環式およびヘテロアリール化合物 |
| WO2020005882A1 (en) | 2018-06-27 | 2020-01-02 | Ptc Therapeutics, Inc. | Heteroaryl compounds for treating huntington's disease |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5478939A (en) * | 1994-07-20 | 1995-12-26 | American Cyanamid Company | (R,R) and (S,S) 2,5-diazabicyclo [2,2,1]heptane derivatives |
| US7265115B2 (en) * | 1999-01-29 | 2007-09-04 | Abbott Laboratories | Diazabicyclic CNS active agents |
| HUP0200332A3 (en) | 1999-01-29 | 2002-09-30 | Abbott Lab | Diazabicyclic derivatives as nicotinic acetylcholine receptor ligands pharmaceutical compositions comprising thereof and their use |
| AU774867B2 (en) | 1999-05-04 | 2004-07-08 | Neurosearch A/S | Heteroaryl diazabicycloalkanes, their preparation and use |
| DE60109924T2 (de) | 2000-05-25 | 2006-02-09 | Targacept, Inc. | Heteroaryldiazabicycloalkane als liganden für den nikotinischen acetylcholin-rezeptor |
| FR2809730B1 (fr) | 2000-05-31 | 2002-07-19 | Sanofi Synthelabo | Derives de 1,4-diazabicyclo[3.2.2] nonanebenzoxazole, -benzothiazole et -benzimidazole, leur preparation et leur application therapeutique |
| FR2809732B1 (fr) | 2000-05-31 | 2002-07-19 | Sanofi Synthelabo | DERIVES DE 4(-2-PHENYLTHIAZOL-5-yl)-1,4-DIAZABICYCLO-[3.2.2] NONANE, LEUR PREPARATION ET LEUR APPLICATION ENTHERAPEUTIQUE |
| FR2809731B1 (fr) | 2000-05-31 | 2002-07-19 | Sanofi Synthelabo | Derives de 1,4-diazabicyclo-[3.2.2] nonane-pheylisoxazole, leur preparation et leur application en therapeutique |
| MXPA03000053A (es) | 2000-07-04 | 2003-09-25 | Neurosearch As | Aril y heteroaril diazabicicloalcanos, su preparacion y uso. |
| DE60215172T2 (de) | 2001-07-06 | 2007-08-30 | Neurosearch A/S | Neue verbindungen, deren herstellung und verwendung |
| US7399765B2 (en) * | 2003-09-19 | 2008-07-15 | Abbott Laboratories | Substituted diazabicycloalkane derivatives |
| MX2007004269A (es) | 2004-10-20 | 2007-06-15 | Neurosearch As | Derivados de arilo diazabiciclico nuevos y su uso medico. |
| JP2008530172A (ja) | 2005-02-16 | 2008-08-07 | ノイロサーチ アクティーゼルスカブ | ジアザ二環系アリール誘導体及びそれらのニコチン様アセチルコリン受容体におけるコリン作動性リガンドとしての使用 |
| AU2006323986A1 (en) | 2005-12-06 | 2007-06-14 | Neurosearch A/S | Novel diazabicyclic aryl derivatives and their medical use |
-
2007
- 2007-05-21 EP EP07729314A patent/EP2029607A1/en not_active Withdrawn
- 2007-05-21 JP JP2009511493A patent/JP2009537599A/ja not_active Abandoned
- 2007-05-21 US US12/298,290 patent/US7910578B2/en not_active Expired - Fee Related
- 2007-05-21 WO PCT/EP2007/054870 patent/WO2007135121A1/en not_active Ceased
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2019500352A (ja) * | 2015-12-10 | 2019-01-10 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
| JP2021042211A (ja) * | 2015-12-10 | 2021-03-18 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
| JP7025508B2 (ja) | 2015-12-10 | 2022-02-24 | ピーティーシー セラピューティクス， インコーポレイテッド | ハンチントン病の治療方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| US20090099153A1 (en) | 2009-04-16 |
| WO2007135121A1 (en) | 2007-11-29 |
| EP2029607A1 (en) | 2009-03-04 |
| US7910578B2 (en) | 2011-03-22 |
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