JP2009535373A5 - - Google Patents
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- Publication number
- JP2009535373A5 JP2009535373A5 JP2009508294A JP2009508294A JP2009535373A5 JP 2009535373 A5 JP2009535373 A5 JP 2009535373A5 JP 2009508294 A JP2009508294 A JP 2009508294A JP 2009508294 A JP2009508294 A JP 2009508294A JP 2009535373 A5 JP2009535373 A5 JP 2009535373A5
- Authority
- JP
- Japan
- Prior art keywords
- virus
- pharmaceutical composition
- composition according
- syndrome
- influenza
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 241000701022 Cytomegalovirus Species 0.000 claims 4
- 208000011580 syndromic disease Diseases 0.000 claims 4
- 241000711573 Coronaviridae Species 0.000 claims 2
- 108010078233 Thymalfasin Proteins 0.000 claims 2
- 102400000800 Thymosin alpha-1 Human genes 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 2
- NZVYCXVTEHPMHE-ZSUJOUNUSA-N thymalfasin Chemical compound CC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O NZVYCXVTEHPMHE-ZSUJOUNUSA-N 0.000 claims 2
- 229960004231 thymalfasin Drugs 0.000 claims 2
- 241001529453 unidentified herpesvirus Species 0.000 claims 2
- 241000712461 unidentified influenza virus Species 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 208000030507 AIDS Diseases 0.000 claims 1
- 101001082142 Homo sapiens Pentraxin-related protein PTX3 Proteins 0.000 claims 1
- 241000725303 Human immunodeficiency virus Species 0.000 claims 1
- 241000712079 Measles morbillivirus Species 0.000 claims 1
- BFHAYPLBUQVNNJ-UHFFFAOYSA-N Pectenotoxin 3 Natural products OC1C(C)CCOC1(O)C1OC2C=CC(C)=CC(C)CC(C)(O3)CCC3C(O3)(O4)CCC3(C=O)CC4C(O3)C(=O)CC3(C)C(O)C(O3)CCC3(O3)CCCC3C(C)C(=O)OC2C1 BFHAYPLBUQVNNJ-UHFFFAOYSA-N 0.000 claims 1
- 102100027351 Pentraxin-related protein PTX3 Human genes 0.000 claims 1
- 241000725643 Respiratory syncytial virus Species 0.000 claims 1
- 241000702670 Rotavirus Species 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- IRSCQMHQWWYFCW-UHFFFAOYSA-N ganciclovir Chemical compound O=C1NC(N)=NC2=C1N=CN2COC(CO)CO IRSCQMHQWWYFCW-UHFFFAOYSA-N 0.000 claims 1
- 229960002963 ganciclovir Drugs 0.000 claims 1
- 208000006454 hepatitis Diseases 0.000 claims 1
- 231100000283 hepatitis Toxicity 0.000 claims 1
- 201000006747 infectious mononucleosis Diseases 0.000 claims 1
- 206010022000 influenza Diseases 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06113401.1 | 2006-05-02 | ||
| EP06113401 | 2006-05-02 | ||
| PCT/EP2007/053574 WO2007128647A1 (en) | 2006-05-02 | 2007-04-12 | USE OF THYMOSIN α1, ALONE OR IN COMBINATION WITH PTX3 OR GANCICLOVIR, FOR THE TREATMENT OF CYTOMEGALOVIRUS INFECTION |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009535373A JP2009535373A (ja) | 2009-10-01 |
| JP2009535373A5 true JP2009535373A5 (https=) | 2010-05-27 |
| JP5441685B2 JP5441685B2 (ja) | 2014-03-12 |
Family
ID=36658736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009508294A Expired - Fee Related JP5441685B2 (ja) | 2006-05-02 | 2007-04-12 | チモシンα１の、単独またはＰＴＸ３またはガンシクロビルとの組合せにおける、サイトメガロウイルス感染の処置のための使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8337828B2 (https=) |
| EP (1) | EP2012816B1 (https=) |
| JP (1) | JP5441685B2 (https=) |
| KR (1) | KR101380360B1 (https=) |
| CN (1) | CN101437535B (https=) |
| AU (1) | AU2007247292B2 (https=) |
| BR (1) | BRPI0711136A2 (https=) |
| CA (1) | CA2649063C (https=) |
| CY (1) | CY1113277T1 (https=) |
| DK (1) | DK2012816T3 (https=) |
| ES (1) | ES2389452T3 (https=) |
| HR (1) | HRP20120676T1 (https=) |
| MX (1) | MX2008013872A (https=) |
| PL (1) | PL2012816T3 (https=) |
| PT (1) | PT2012816E (https=) |
| RS (1) | RS52377B (https=) |
| SI (1) | SI2012816T1 (https=) |
| WO (1) | WO2007128647A1 (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1298487B1 (it) * | 1997-12-19 | 2000-01-10 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche comprendenti pentraxina lunga ptx3 per la terapia di patologie di tipo infettivo, infiammatorio o tumorale, |
| ITRM20040223A1 (it) * | 2004-05-07 | 2004-08-07 | Sigma Tau Ind Farmaceuti | Medicamento per il trattamento delle infezioni fungine, in particolare dell'aspergillosi. |
| EP1832295A1 (en) * | 2006-03-10 | 2007-09-12 | Tecnogen S.P.A. | Use of PTX3 for the treatment of viral diseases |
| US8829173B2 (en) * | 2008-09-26 | 2014-09-09 | Tocagen Inc. | Recombinant vectors |
| WO2010129947A2 (en) * | 2009-05-08 | 2010-11-11 | Sciclone Pharmaceuticals, Inc. | Alpha thymosin peptides as vaccine enhancers |
| US20140213506A1 (en) * | 2011-02-09 | 2014-07-31 | Cynthia W. TUTHILL | Thymosin alpha peptide for preventing, reducing the severity of, and treating infection |
| ES2786051T3 (es) | 2012-10-25 | 2020-10-08 | Tocagen Inc | Vector retroviral con casete de mini-promotor |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6106868A (en) * | 1990-08-24 | 2000-08-22 | The Board Of Governors Of Wayne State University | Method for the treatment of hepatitis |
| TW224053B (https=) * | 1991-09-13 | 1994-05-21 | Paul B Chretien | |
| CN1072961C (zh) * | 1993-03-05 | 2001-10-17 | 施塞克龙药品公司 | 治疗对干扰素治疗无反应者的丙型肝炎的方法 |
| US6200952B1 (en) * | 1993-06-02 | 2001-03-13 | Sciclone Pharmaceuticals, Inc. | Combination therapy method for treating chronic hepatitis B |
| US5632983A (en) * | 1994-11-17 | 1997-05-27 | University Of South Florida | Method for treating secondary immunodeficiency |
| WO1998018491A1 (en) * | 1996-10-28 | 1998-05-07 | BURGSTINER, Jacqueline, Cook | Methods and compositions for dietary supplementation |
| US5939423A (en) * | 1997-04-16 | 1999-08-17 | Sciclone Pharmaceuticals, Inc. | Treatment of hepatitis B infection with thymosin alpha 1 and famciclovir |
| IT1298487B1 (it) * | 1997-12-19 | 2000-01-10 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche comprendenti pentraxina lunga ptx3 per la terapia di patologie di tipo infettivo, infiammatorio o tumorale, |
| US6288033B1 (en) * | 1998-09-25 | 2001-09-11 | Sciclone Pharmaceuticals, Inc. | Treatment of hepatitis B infection with thymosin alpha 1 in combination with lamivudine or in combination with lamivudine and famciclovir |
| IT1317927B1 (it) | 2000-11-03 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patologie autoimmuni. |
| IT1317930B1 (it) | 2000-11-08 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patalogie associate ad una alterata attivazione |
| US20040198655A1 (en) | 2001-08-03 | 2004-10-07 | Alberto Mantovani | Use of long pentraxin ptx3 for treating female infertility |
| WO2003035111A1 (en) * | 2001-10-24 | 2003-05-01 | Sciclone Pharmaceuticals, Inc. | Antiretroviral compositions comprising thymosin alpha peptides and protease inhibitors |
| JP2006524704A (ja) * | 2003-04-23 | 2006-11-02 | サイクローン・ファーマシューティカルズ・インコーポレイテッド | アルファチモシンペプチドによる呼吸器ウイルス感染の治療または予防 |
| ITRM20030596A1 (it) | 2003-12-23 | 2005-06-24 | Sigma Tau Ind Farmaceuti | Uso di inibitori della pentraxina lunga ptx3, per la preparazione di un medicamento per la prevenzione e cura di patologie che rispondono all'inibizione dell'attivita' biologica di detta ptx3. |
| EP1832295A1 (en) * | 2006-03-10 | 2007-09-12 | Tecnogen S.P.A. | Use of PTX3 for the treatment of viral diseases |
-
2007
- 2007-04-12 RS RS20120363A patent/RS52377B/sr unknown
- 2007-04-12 EP EP07728041A patent/EP2012816B1/en active Active
- 2007-04-12 KR KR1020087029405A patent/KR101380360B1/ko not_active Expired - Fee Related
- 2007-04-12 DK DK07728041.0T patent/DK2012816T3/da active
- 2007-04-12 PT PT07728041T patent/PT2012816E/pt unknown
- 2007-04-12 WO PCT/EP2007/053574 patent/WO2007128647A1/en not_active Ceased
- 2007-04-12 HR HRP20120676TT patent/HRP20120676T1/hr unknown
- 2007-04-12 SI SI200730976T patent/SI2012816T1/sl unknown
- 2007-04-12 ES ES07728041T patent/ES2389452T3/es active Active
- 2007-04-12 CA CA2649063A patent/CA2649063C/en not_active Expired - Fee Related
- 2007-04-12 BR BRPI0711136-3A patent/BRPI0711136A2/pt not_active IP Right Cessation
- 2007-04-12 US US12/298,643 patent/US8337828B2/en not_active Expired - Fee Related
- 2007-04-12 AU AU2007247292A patent/AU2007247292B2/en not_active Ceased
- 2007-04-12 JP JP2009508294A patent/JP5441685B2/ja not_active Expired - Fee Related
- 2007-04-12 MX MX2008013872A patent/MX2008013872A/es active IP Right Grant
- 2007-04-12 PL PL07728041T patent/PL2012816T3/pl unknown
- 2007-04-12 CN CN2007800159035A patent/CN101437535B/zh not_active Expired - Fee Related
-
2012
- 2012-08-23 CY CY20121100756T patent/CY1113277T1/el unknown
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