JP2009535373A5 - - Google Patents
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- Publication number
- JP2009535373A5 JP2009535373A5 JP2009508294A JP2009508294A JP2009535373A5 JP 2009535373 A5 JP2009535373 A5 JP 2009535373A5 JP 2009508294 A JP2009508294 A JP 2009508294A JP 2009508294 A JP2009508294 A JP 2009508294A JP 2009535373 A5 JP2009535373 A5 JP 2009535373A5
- Authority
- JP
- Japan
- Prior art keywords
- virus
- pharmaceutical composition
- composition according
- syndrome
- influenza
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 8
- 241000701022 Cytomegalovirus Species 0.000 claims 4
- 208000011580 syndromic disease Diseases 0.000 claims 4
- 241000711573 Coronaviridae Species 0.000 claims 2
- 108010078233 Thymalfasin Proteins 0.000 claims 2
- 102400000800 Thymosin alpha-1 Human genes 0.000 claims 2
- 241000700605 Viruses Species 0.000 claims 2
- NZVYCXVTEHPMHE-ZSUJOUNUSA-N thymalfasin Chemical compound CC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(O)=O NZVYCXVTEHPMHE-ZSUJOUNUSA-N 0.000 claims 2
- 229960004231 thymalfasin Drugs 0.000 claims 2
- 241001529453 unidentified herpesvirus Species 0.000 claims 2
- 241000712461 unidentified influenza virus Species 0.000 claims 2
- 230000003612 virological effect Effects 0.000 claims 2
- 208000030507 AIDS Diseases 0.000 claims 1
- 101001082142 Homo sapiens Pentraxin-related protein PTX3 Proteins 0.000 claims 1
- 241000725303 Human immunodeficiency virus Species 0.000 claims 1
- 241000712079 Measles morbillivirus Species 0.000 claims 1
- BFHAYPLBUQVNNJ-UHFFFAOYSA-N Pectenotoxin 3 Natural products OC1C(C)CCOC1(O)C1OC2C=CC(C)=CC(C)CC(C)(O3)CCC3C(O3)(O4)CCC3(C=O)CC4C(O3)C(=O)CC3(C)C(O)C(O3)CCC3(O3)CCCC3C(C)C(=O)OC2C1 BFHAYPLBUQVNNJ-UHFFFAOYSA-N 0.000 claims 1
- 102100027351 Pentraxin-related protein PTX3 Human genes 0.000 claims 1
- 241000725643 Respiratory syncytial virus Species 0.000 claims 1
- 241000702670 Rotavirus Species 0.000 claims 1
- 230000004913 activation Effects 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- IRSCQMHQWWYFCW-UHFFFAOYSA-N ganciclovir Chemical compound O=C1NC(N)=NC2=C1N=CN2COC(CO)CO IRSCQMHQWWYFCW-UHFFFAOYSA-N 0.000 claims 1
- 229960002963 ganciclovir Drugs 0.000 claims 1
- 208000006454 hepatitis Diseases 0.000 claims 1
- 231100000283 hepatitis Toxicity 0.000 claims 1
- 201000006747 infectious mononucleosis Diseases 0.000 claims 1
- 206010022000 influenza Diseases 0.000 claims 1
- 230000005764 inhibitory process Effects 0.000 claims 1
- 210000000056 organ Anatomy 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP06113401 | 2006-05-02 | ||
| EP06113401.1 | 2006-05-02 | ||
| PCT/EP2007/053574 WO2007128647A1 (en) | 2006-05-02 | 2007-04-12 | USE OF THYMOSIN α1, ALONE OR IN COMBINATION WITH PTX3 OR GANCICLOVIR, FOR THE TREATMENT OF CYTOMEGALOVIRUS INFECTION |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009535373A JP2009535373A (ja) | 2009-10-01 |
| JP2009535373A5 true JP2009535373A5 (enExample) | 2010-05-27 |
| JP5441685B2 JP5441685B2 (ja) | 2014-03-12 |
Family
ID=36658736
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009508294A Expired - Fee Related JP5441685B2 (ja) | 2006-05-02 | 2007-04-12 | チモシンα１の、単独またはＰＴＸ３またはガンシクロビルとの組合せにおける、サイトメガロウイルス感染の処置のための使用 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US8337828B2 (enExample) |
| EP (1) | EP2012816B1 (enExample) |
| JP (1) | JP5441685B2 (enExample) |
| KR (1) | KR101380360B1 (enExample) |
| CN (1) | CN101437535B (enExample) |
| AU (1) | AU2007247292B2 (enExample) |
| BR (1) | BRPI0711136A2 (enExample) |
| CA (1) | CA2649063C (enExample) |
| CY (1) | CY1113277T1 (enExample) |
| DK (1) | DK2012816T3 (enExample) |
| ES (1) | ES2389452T3 (enExample) |
| HR (1) | HRP20120676T1 (enExample) |
| MX (1) | MX2008013872A (enExample) |
| PL (1) | PL2012816T3 (enExample) |
| PT (1) | PT2012816E (enExample) |
| RS (1) | RS52377B (enExample) |
| SI (1) | SI2012816T1 (enExample) |
| WO (1) | WO2007128647A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1298487B1 (it) * | 1997-12-19 | 2000-01-10 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche comprendenti pentraxina lunga ptx3 per la terapia di patologie di tipo infettivo, infiammatorio o tumorale, |
| ITRM20040223A1 (it) * | 2004-05-07 | 2004-08-07 | Sigma Tau Ind Farmaceuti | Medicamento per il trattamento delle infezioni fungine, in particolare dell'aspergillosi. |
| EP1832295A1 (en) * | 2006-03-10 | 2007-09-12 | Tecnogen S.P.A. | Use of PTX3 for the treatment of viral diseases |
| US8829173B2 (en) * | 2008-09-26 | 2014-09-09 | Tocagen Inc. | Recombinant vectors |
| CN102458470B (zh) * | 2009-05-08 | 2016-01-20 | 赛生制药有限公司 | 作为疫苗增强剂的α胸腺素肽 |
| EP2675272A4 (en) * | 2011-02-09 | 2015-03-11 | Sciclone Pharmaceuticals Inc | THYMOSINE ALPHA PEPTIDE FOR THE PREVENTION, TREATMENT AND TREATMENT OF INFECTIONS |
| JP6419706B2 (ja) | 2012-10-25 | 2018-11-07 | トカジェン インコーポレーテッド | ミニプロモーターカセットを含むレトロウイルスベクター |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6106868A (en) | 1990-08-24 | 2000-08-22 | The Board Of Governors Of Wayne State University | Method for the treatment of hepatitis |
| TW224053B (enExample) * | 1991-09-13 | 1994-05-21 | Paul B Chretien | |
| CN1072961C (zh) * | 1993-03-05 | 2001-10-17 | 施塞克龙药品公司 | 治疗对干扰素治疗无反应者的丙型肝炎的方法 |
| US6200952B1 (en) * | 1993-06-02 | 2001-03-13 | Sciclone Pharmaceuticals, Inc. | Combination therapy method for treating chronic hepatitis B |
| US5632983A (en) * | 1994-11-17 | 1997-05-27 | University Of South Florida | Method for treating secondary immunodeficiency |
| WO1998018491A1 (en) * | 1996-10-28 | 1998-05-07 | BURGSTINER, Jacqueline, Cook | Methods and compositions for dietary supplementation |
| US5939423A (en) | 1997-04-16 | 1999-08-17 | Sciclone Pharmaceuticals, Inc. | Treatment of hepatitis B infection with thymosin alpha 1 and famciclovir |
| IT1298487B1 (it) * | 1997-12-19 | 2000-01-10 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche comprendenti pentraxina lunga ptx3 per la terapia di patologie di tipo infettivo, infiammatorio o tumorale, |
| US6288033B1 (en) | 1998-09-25 | 2001-09-11 | Sciclone Pharmaceuticals, Inc. | Treatment of hepatitis B infection with thymosin alpha 1 in combination with lamivudine or in combination with lamivudine and famciclovir |
| IT1317927B1 (it) | 2000-11-03 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patologie autoimmuni. |
| IT1317930B1 (it) | 2000-11-08 | 2003-07-15 | Sigma Tau Ind Farmaceuti | Uso della pentraxina lunga ptx3 per la preparazione di un medicamentoper il trattamento di patalogie associate ad una alterata attivazione |
| PT1411971E (pt) | 2001-08-03 | 2006-07-31 | Sigma Tau Ind Farmaceuti | Utilizacao de pentraxina longa ptx3 para o tratamento de infertilidade feminina |
| WO2003035111A1 (en) | 2001-10-24 | 2003-05-01 | Sciclone Pharmaceuticals, Inc. | Antiretroviral compositions comprising thymosin alpha peptides and protease inhibitors |
| US20070036744A1 (en) * | 2003-04-23 | 2007-02-15 | Sciclone Pharmaceuticals, Inc. | Treatment or prevention of respiratory viral infections with alpha thymosin peptides |
| ITRM20030596A1 (it) | 2003-12-23 | 2005-06-24 | Sigma Tau Ind Farmaceuti | Uso di inibitori della pentraxina lunga ptx3, per la preparazione di un medicamento per la prevenzione e cura di patologie che rispondono all'inibizione dell'attivita' biologica di detta ptx3. |
| EP1832295A1 (en) * | 2006-03-10 | 2007-09-12 | Tecnogen S.P.A. | Use of PTX3 for the treatment of viral diseases |
-
2007
- 2007-04-12 CN CN2007800159035A patent/CN101437535B/zh not_active Expired - Fee Related
- 2007-04-12 SI SI200730976T patent/SI2012816T1/sl unknown
- 2007-04-12 US US12/298,643 patent/US8337828B2/en not_active Expired - Fee Related
- 2007-04-12 RS RS20120363A patent/RS52377B/sr unknown
- 2007-04-12 WO PCT/EP2007/053574 patent/WO2007128647A1/en not_active Ceased
- 2007-04-12 KR KR1020087029405A patent/KR101380360B1/ko not_active Expired - Fee Related
- 2007-04-12 DK DK07728041.0T patent/DK2012816T3/da active
- 2007-04-12 ES ES07728041T patent/ES2389452T3/es active Active
- 2007-04-12 AU AU2007247292A patent/AU2007247292B2/en not_active Ceased
- 2007-04-12 EP EP07728041A patent/EP2012816B1/en active Active
- 2007-04-12 HR HRP20120676TT patent/HRP20120676T1/hr unknown
- 2007-04-12 PT PT07728041T patent/PT2012816E/pt unknown
- 2007-04-12 CA CA2649063A patent/CA2649063C/en not_active Expired - Fee Related
- 2007-04-12 PL PL07728041T patent/PL2012816T3/pl unknown
- 2007-04-12 MX MX2008013872A patent/MX2008013872A/es active IP Right Grant
- 2007-04-12 BR BRPI0711136-3A patent/BRPI0711136A2/pt not_active IP Right Cessation
- 2007-04-12 JP JP2009508294A patent/JP5441685B2/ja not_active Expired - Fee Related
-
2012
- 2012-08-23 CY CY20121100756T patent/CY1113277T1/el unknown
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