JP2009532019A - 膜ホーミングポリペプチドにより一過性にトランスフェクトされた樹状細胞およびそれらの使用 - Google Patents

膜ホーミングポリペプチドにより一過性にトランスフェクトされた樹状細胞およびそれらの使用 Download PDF

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JP2009532019A
JP2009532019A JP2008555751A JP2008555751A JP2009532019A JP 2009532019 A JP2009532019 A JP 2009532019A JP 2008555751 A JP2008555751 A JP 2008555751A JP 2008555751 A JP2008555751 A JP 2008555751A JP 2009532019 A JP2009532019 A JP 2009532019A
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cells
antigen
cell
selectin
rna
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JP2009532019A5 (https=
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ゲロルト、シュラー
ニールス、シャフト
ヤン、デリー
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アルゴス セラピューティクス,インコーポレイティド
キリンファーマ株式会社
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Priority claimed from EP20060110306 external-priority patent/EP1825859A1/en
Application filed by アルゴス セラピューティクス,インコーポレイティド, キリンファーマ株式会社 filed Critical アルゴス セラピューティクス,インコーポレイティド
Publication of JP2009532019A publication Critical patent/JP2009532019A/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/19Dendritic cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/20Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24Antigen-presenting cells [APC]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4254Adhesion molecules, e.g. NRCAM, EpCAM or cadherins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4271Melanoma antigens
    • A61K40/4272Melan-A/MART
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2239/00Indexing codes associated with cellular immunotherapy of group A61K40/00
    • A61K2239/31Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
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  • Epidemiology (AREA)
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  • Genetics & Genomics (AREA)
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  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Developmental Biology & Embryology (AREA)
  • Plant Pathology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Oncology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP2008555751A 2006-02-22 2007-02-14 膜ホーミングポリペプチドにより一過性にトランスフェクトされた樹状細胞およびそれらの使用 Pending JP2009532019A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US77573506P 2006-02-22 2006-02-22
EP20060110306 EP1825859A1 (en) 2006-02-22 2006-02-22 Dendritic cells transiently transfected with a membrane homing polypeptide and their use
PCT/EP2007/051417 WO2007096278A1 (en) 2006-02-22 2007-02-14 Dendritic cells transiently transfected with a membrane homing polypeptide and their use

Publications (2)

Publication Number Publication Date
JP2009532019A true JP2009532019A (ja) 2009-09-10
JP2009532019A5 JP2009532019A5 (https=) 2011-02-03

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ID=37944318

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JP2008555751A Pending JP2009532019A (ja) 2006-02-22 2007-02-14 膜ホーミングポリペプチドにより一過性にトランスフェクトされた樹状細胞およびそれらの使用

Country Status (7)

Country Link
US (1) US20090274669A1 (https=)
EP (1) EP1986667A1 (https=)
JP (1) JP2009532019A (https=)
KR (1) KR20080106193A (https=)
AU (1) AU2007217630A1 (https=)
CA (1) CA2642999A1 (https=)
WO (1) WO2007096278A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2072618A1 (en) * 2007-12-14 2009-06-24 Johannes Gutenberg-Universität Mainz Use of RNA for reprogramming somatic cells
EP2254998B1 (en) 2008-02-28 2015-12-23 Argos Therapeutics, Inc. Transient expression of immunomodulatory polypeptides for the prevention and treatment of autoimmune disease, allergy and transplant rejection
EP2281579A1 (en) 2009-08-05 2011-02-09 BioNTech AG Vaccine composition comprising 5'-Cap modified RNA
WO2015127190A1 (en) * 2014-02-21 2015-08-27 Argos Therapeutics, Inc. Tscm cells and methods for use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000060055A1 (en) * 1999-04-01 2000-10-12 The Brigham And Women's Hospital, Inc. Modified dendritic cells and uses therefor
US6929792B1 (en) * 1999-04-01 2005-08-16 The Brigham & Women's Hospital, Inc. Modified dendritic cells and use therefor
US7547551B2 (en) * 2001-06-21 2009-06-16 University Of Antwerp. Transfection of eukaryontic cells with linear polynucleotides by electroporation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6012025791; Gene Ther., 10[17](2003) p.1479-1486 *
JPN6012025793; J. Immunother., 25[6](2002) p.445-454 *
JPN6012025795; J. Immunol., 174[5](2005) p.3087-3097 *

Also Published As

Publication number Publication date
AU2007217630A1 (en) 2007-08-30
WO2007096278A1 (en) 2007-08-30
KR20080106193A (ko) 2008-12-04
EP1986667A1 (en) 2008-11-05
US20090274669A1 (en) 2009-11-05
CA2642999A1 (en) 2007-08-30
AU2007217630A8 (en) 2010-04-15

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