JP2009520485A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2009520485A5 JP2009520485A5 JP2008546487A JP2008546487A JP2009520485A5 JP 2009520485 A5 JP2009520485 A5 JP 2009520485A5 JP 2008546487 A JP2008546487 A JP 2008546487A JP 2008546487 A JP2008546487 A JP 2008546487A JP 2009520485 A5 JP2009520485 A5 JP 2009520485A5
- Authority
- JP
- Japan
- Prior art keywords
- tango
- beta
- algorithm
- aggregation
- self
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000004169 proteins and genes Human genes 0.000 description 7
- 108090000623 proteins and genes Proteins 0.000 description 7
- 238000004422 calculation algorithm Methods 0.000 description 6
- 230000002776 aggregation Effects 0.000 description 5
- 238000004220 aggregation Methods 0.000 description 5
- 108090000765 processed proteins & peptides Proteins 0.000 description 5
- 238000005400 testing for adjacent nuclei with gyration operator Methods 0.000 description 4
- 238000012740 TANGO algorithm Methods 0.000 description 2
- 125000003275 alpha amino acid group Chemical group 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 102000004196 processed proteins & peptides Human genes 0.000 description 2
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 description 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 description 1
- 102000005431 Molecular Chaperones Human genes 0.000 description 1
- 108010006519 Molecular Chaperones Proteins 0.000 description 1
- 230000004931 aggregating effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 210000000805 cytoplasm Anatomy 0.000 description 1
- 230000009881 electrostatic interaction Effects 0.000 description 1
- 210000002744 extracellular matrix Anatomy 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 238000005192 partition Methods 0.000 description 1
- 238000007614 solvation Methods 0.000 description 1
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75324505P | 2005-12-22 | 2005-12-22 | |
| US60/753,245 | 2005-12-22 | ||
| EP05112761.1 | 2005-12-22 | ||
| EP05112761 | 2005-12-22 | ||
| EP06125189.8 | 2006-12-01 | ||
| EP06125189 | 2006-12-01 | ||
| PCT/EP2006/070184 WO2007071789A1 (en) | 2005-12-22 | 2006-12-22 | Means and methods for mediating protein interference |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014075577A Division JP2014144011A (ja) | 2005-12-22 | 2014-04-01 | タンパク質干渉を媒介する手段および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2009520485A JP2009520485A (ja) | 2009-05-28 |
| JP2009520485A5 true JP2009520485A5 (https=) | 2012-06-14 |
| JP5888832B2 JP5888832B2 (ja) | 2016-03-22 |
Family
ID=40785299
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008546487A Expired - Fee Related JP5888832B2 (ja) | 2005-12-22 | 2006-12-22 | タンパク質干渉を媒介する手段および方法 |
| JP2014075577A Withdrawn JP2014144011A (ja) | 2005-12-22 | 2014-04-01 | タンパク質干渉を媒介する手段および方法 |
| JP2016221100A Withdrawn JP2017074046A (ja) | 2005-12-22 | 2016-11-14 | タンパク質干渉を媒介する手段および方法 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014075577A Withdrawn JP2014144011A (ja) | 2005-12-22 | 2014-04-01 | タンパク質干渉を媒介する手段および方法 |
| JP2016221100A Withdrawn JP2017074046A (ja) | 2005-12-22 | 2016-11-14 | タンパク質干渉を媒介する手段および方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (3) | JP5888832B2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5888832B2 (ja) * | 2005-12-22 | 2016-03-22 | フラームス・インテルウニフェルシタイル・インステイチュート・フォール・ビオテヒノロヒー・ヴェーゼットウェー（ヴェーイーベー・ヴェーゼットウェー）Ｖｌａａｍｓ Ｉｎｔｅｒｕｎｉｖｅｒｓｉｔａｉｒ Ｉｎｓｔｉｔｕｕｔ Ｖｏｏｒ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅ Ｖｚｗ（Ｖｉｂ Ｖｚｗ） | タンパク質干渉を媒介する手段および方法 |
| EP3384939A1 (en) * | 2011-03-11 | 2018-10-10 | Vib Vzw | Molecules and methods for inhibition and detection of proteins |
| CA3177489A1 (en) * | 2020-02-19 | 2021-08-26 | Aelin Therapeutics | Molecules targeting proteins |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5854204A (en) * | 1995-03-14 | 1998-12-29 | Praecis Pharmaceuticals, Inc. | Aβ peptides that modulate β-amyloid aggregation |
| US20030064384A1 (en) * | 2001-04-02 | 2003-04-03 | Mien-Chie Hung | Beta-catenin is a strong and independent prognostic factor for cancer |
| EP1325930A1 (en) * | 2002-01-08 | 2003-07-09 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Mammal prolactin variants |
| JP5888832B2 (ja) * | 2005-12-22 | 2016-03-22 | フラームス・インテルウニフェルシタイル・インステイチュート・フォール・ビオテヒノロヒー・ヴェーゼットウェー（ヴェーイーベー・ヴェーゼットウェー）Ｖｌａａｍｓ Ｉｎｔｅｒｕｎｉｖｅｒｓｉｔａｉｒ Ｉｎｓｔｉｔｕｕｔ Ｖｏｏｒ Ｂｉｏｔｅｃｈｎｏｌｏｇｉｅ Ｖｚｗ（Ｖｉｂ Ｖｚｗ） | タンパク質干渉を媒介する手段および方法 |
-
2006
- 2006-12-22 JP JP2008546487A patent/JP5888832B2/ja not_active Expired - Fee Related
-
2014
- 2014-04-01 JP JP2014075577A patent/JP2014144011A/ja not_active Withdrawn
-
2016
- 2016-11-14 JP JP2016221100A patent/JP2017074046A/ja not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Nicolas et al. | Becker muscular dystrophy severity is linked to the structure of dystrophin | |
| Fukunaga et al. | CapR: revealing structural specificities of RNA-binding protein target recognition using CLIP-seq data | |
| Prabakaran et al. | Protein aggregation: in silico algorithms and applications | |
| Kerpedjiev et al. | Predicting RNA 3D structure using a coarse-grain helix-centered model | |
| Li et al. | RNAJP: enhanced RNA 3D structure predictions with non-canonical interactions and global topology sampling | |
| Jacak et al. | Computational protein design with explicit consideration of surface hydrophobic patches | |
| Gong et al. | Local secondary structure content predicts folding rates for simple, two-state proteins | |
| Vieth et al. | Prediction of the folding pathways and structure of the GCN4 leucine zipper | |
| Feig et al. | Evaluating CASP4 predictions with physical energy functions | |
| Chen et al. | Discriminating cirRNAs from other lncRNAs using a hierarchical extreme learning machine (H-ELM) algorithm with feature selection | |
| Wang et al. | Scoring functions for prediction of protein-ligand interactions | |
| Adhikari et al. | Simplified Protein Models: Predicting Folding Pathways and Structure<? format?> Using Amino Acid Sequences | |
| Xu et al. | VfoldLA: a web server for loop assembly-based prediction of putative 3D RNA structures | |
| Panwar et al. | Identification of protein-interacting nucleotides in a RNA sequence using composition profile of tri-nucleotides | |
| Bao et al. | Molecular dynamics simulation of the binding process of ligands to the add adenine riboswitch aptamer | |
| JP2009520485A5 (https=) | ||
| Ma et al. | What determines protein folding type? An investigation of intrinsic structural properties and its implications for understanding folding mechanisms | |
| Eriksson et al. | De novo tertiary structure prediction using RNA123—Benchmarking and application to Macugen | |
| Xu et al. | A method to predict the 3D structure of an RNA scaffold | |
| Gardner et al. | Statistical potentials for hairpin and internal loops improve the accuracy of the predicted RNA structure | |
| Gaye et al. | Chameleonicity and folding of the C-fragment of TOP7 | |
| Halder et al. | Subpopulations of soluble, misfolded proteins commonly bypass chaperones: How it happens at the molecular level | |
| Vinogradov | Large scale of human duplicate genes divergence | |
| Liu et al. | Predicting scheme of RNA folding structure including pseudoknots | |
| Kircher et al. | Running spell-check to identify regulatory variants |