JP2009515831A5 - - Google Patents
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- Publication number
- JP2009515831A5 JP2009515831A5 JP2008537233A JP2008537233A JP2009515831A5 JP 2009515831 A5 JP2009515831 A5 JP 2009515831A5 JP 2008537233 A JP2008537233 A JP 2008537233A JP 2008537233 A JP2008537233 A JP 2008537233A JP 2009515831 A5 JP2009515831 A5 JP 2009515831A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- antigens
- immunogenic composition
- combination
- pestis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000427 antigen Substances 0.000 claims 370
- 102000036639 antigens Human genes 0.000 claims 370
- 108091007433 antigens Proteins 0.000 claims 370
- 230000002163 immunogen Effects 0.000 claims 54
- 241000124008 Mammalia Species 0.000 claims 9
- 230000028993 immune response Effects 0.000 claims 9
- 239000003814 drug Substances 0.000 claims 8
- 238000004519 manufacturing process Methods 0.000 claims 8
- 101100421109 Yersinia pestis secM gene Proteins 0.000 claims 5
- 101100493693 Yersinia pestis bamC gene Proteins 0.000 claims 4
- 101100116909 Yersinia pestis djlA gene Proteins 0.000 claims 4
- 101100294224 Yersinia pestis nlpI gene Proteins 0.000 claims 4
- 238000002560 therapeutic procedure Methods 0.000 claims 4
- 101100381447 Yersinia pestis bamA gene Proteins 0.000 claims 3
- 101100440427 Yersinia pestis coaE gene Proteins 0.000 claims 3
- 101100281900 Yersinia pestis fyuA gene Proteins 0.000 claims 3
- 101100220525 Yersinia pestis groEL gene Proteins 0.000 claims 3
- 101100188657 Yersinia pestis ompA gene Proteins 0.000 claims 3
- 101100060882 Yersinia pestis pla gene Proteins 0.000 claims 3
- 101100475179 Yersinia pestis rpsC gene Proteins 0.000 claims 3
- 101100093726 Yersinia pestis rpsD gene Proteins 0.000 claims 3
- 101100256513 Yersinia pestis secB gene Proteins 0.000 claims 3
- 101100478915 Yersinia pestis surA gene Proteins 0.000 claims 3
- 101100118435 Yersinia pestis tufA gene Proteins 0.000 claims 3
- -1 YPO0501 Proteins 0.000 claims 2
- 101100170819 Yersinia pestis dnaK gene Proteins 0.000 claims 2
- 101100064180 Yersinia pestis dsbA gene Proteins 0.000 claims 2
- 101100393774 Yersinia pestis hemL gene Proteins 0.000 claims 2
- 101100126385 Yersinia pestis ispD gene Proteins 0.000 claims 2
- 101100472136 Yersinia pestis rplI gene Proteins 0.000 claims 2
- 101100365859 Yersinia pestis skp gene Proteins 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 241000894006 Bacteria Species 0.000 claims 1
- 241000607479 Yersinia pestis Species 0.000 claims 1
- 101100370051 Yersinia pestis tolB gene Proteins 0.000 claims 1
- 101100207359 Yersinia pestis tpx gene Proteins 0.000 claims 1
- 108020001507 fusion proteins Proteins 0.000 claims 1
- 102000037865 fusion proteins Human genes 0.000 claims 1
- 239000002955 immunomodulating agent Substances 0.000 claims 1
- 229940121354 immunomodulator Drugs 0.000 claims 1
- 229920001184 polypeptide Polymers 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73018205P | 2005-10-25 | 2005-10-25 | |
| US81783806P | 2006-06-30 | 2006-06-30 | |
| PCT/IB2006/003843 WO2007049155A2 (en) | 2005-10-25 | 2006-10-25 | Compositions comprising yersinia pestis antigens |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009515831A JP2009515831A (ja) | 2009-04-16 |
| JP2009515831A5 true JP2009515831A5 (https=) | 2010-11-11 |
Family
ID=37968196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008537233A Pending JP2009515831A (ja) | 2005-10-25 | 2006-10-25 | ペスト菌（Ｙｅｒｓｉｎｉａｐｅｓｔｉｓ）抗原を含む組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US7776336B2 (https=) |
| EP (1) | EP1954306A2 (https=) |
| JP (1) | JP2009515831A (https=) |
| AU (1) | AU2006307602A1 (https=) |
| CA (1) | CA2627302A1 (https=) |
| WO (1) | WO2007049155A2 (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7082569B2 (en) | 2001-01-17 | 2006-07-25 | Outlooksoft Corporation | Systems and methods providing dynamic spreadsheet functionality |
| GB0525213D0 (en) * | 2005-12-12 | 2006-01-18 | Secr Defence | Vaccine |
| US10174100B1 (en) * | 2006-11-06 | 2019-01-08 | Microvax, Llc | Multivalent DNA composition for Yersinia pestis |
| GB0717187D0 (en) * | 2007-09-04 | 2007-10-17 | Novartis Ag | Compositions comprising yersinia pestis antigens |
| WO2010117455A2 (en) * | 2009-04-08 | 2010-10-14 | U.S. Army Medical Research Institute Of Infectious Diseases | Human monoclonal antibodies protective against bubonic plaque |
| ITMI20090946A1 (it) | 2009-05-28 | 2010-11-29 | Novartis Ag | Espressione di proteine ricombinanti |
| WO2011066454A1 (en) * | 2009-11-24 | 2011-06-03 | Inviragen, Inc. | Compositions, methods and uses for expression of enterobacterium-associated peptides |
| US9770463B2 (en) | 2010-07-06 | 2017-09-26 | Glaxosmithkline Biologicals Sa | Delivery of RNA to different cell types |
| MX342608B (es) | 2010-07-06 | 2016-10-06 | Novartis Ag * | Particulas de suministro similares a viriones para moleculas de arn de autorreplicacion. |
| ES2557382T3 (es) | 2010-07-06 | 2016-01-25 | Glaxosmithkline Biologicals Sa | Liposomas con lípidos que tienen un valor de pKa ventajoso para el suministro de ARN |
| EP2591114B1 (en) | 2010-07-06 | 2016-06-08 | GlaxoSmithKline Biologicals SA | Immunisation of large mammals with low doses of rna |
| ES2646669T3 (es) | 2010-07-06 | 2017-12-14 | Glaxosmithkline Biologicals Sa | Procedimientos de aumento de una respuesta inmunitaria mediante el suministro de ARN |
| LT4226941T (lt) | 2010-08-31 | 2025-01-10 | Glaxosmithkline Biologicals Sa | Pegilintos liposomos, skirtos imunogeną koduojančios rnr pristatymui |
| MX2013002332A (es) | 2010-08-31 | 2013-03-18 | Novartis Ag | Lipidos apropiados para suministro liposomal del arn que codifica la proteina. |
| WO2012051211A2 (en) | 2010-10-11 | 2012-04-19 | Novartis Ag | Antigen delivery platforms |
| EP2667852B1 (en) | 2011-01-27 | 2016-11-09 | GlaxoSmithKline Biologicals SA | Adjuvant nanoemulsions with crystallisation inhibitors |
| WO2012129483A1 (en) | 2011-03-24 | 2012-09-27 | Novartis Ag | Adjuvant nanoemulsions with phospholipids |
| EP2729165B1 (en) | 2011-07-06 | 2017-11-08 | GlaxoSmithKline Biologicals SA | Immunogenic combination compositions and uses thereof |
| EP4115875A1 (en) | 2011-07-06 | 2023-01-11 | GlaxoSmithKline Biologicals S.A. | Liposomes having useful n:p ratio for delivery of rna molecules |
| MX366055B (es) | 2011-08-31 | 2019-06-26 | Novartis Ag | Liposomas pegilados para admistracion de acido ribonucleico (arn) que codifica para inmunogeno. |
| JP6283674B2 (ja) | 2012-09-18 | 2018-02-21 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 外膜小胞 |
| CN107879960B (zh) | 2013-03-08 | 2021-06-22 | 诺华股份有限公司 | 用于传递活性成分的脂质和脂质组合物 |
| EP3083556B1 (en) | 2013-12-19 | 2019-12-25 | Novartis AG | Lipids and lipid compositions for the delivery of active agents |
| US10426737B2 (en) | 2013-12-19 | 2019-10-01 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
| CN106794141B (zh) | 2014-07-16 | 2021-05-28 | 诺华股份有限公司 | 将核酸包封在脂质纳米粒主体中的方法 |
| US10125092B2 (en) | 2014-09-05 | 2018-11-13 | Novartis Ag | Lipids and lipid compositions for the delivery of active agents |
| EP3061826A1 (en) | 2015-02-27 | 2016-08-31 | Novartis AG | Flavivirus replicons |
| EP4228658A4 (en) | 2020-10-14 | 2025-02-19 | George Mason Research Foundation, Inc. | IONIZABLE LIPIDS AND METHODS FOR THE PRODUCTION AND USE THEREOF |
| CN112609013A (zh) * | 2021-01-12 | 2021-04-06 | 深圳市赛格诺生物科技有限公司 | 一种用于检测鼠疫耶尔森菌的荧光pcr试剂及方法 |
| EP4387596A1 (en) | 2021-08-16 | 2024-06-26 | GlaxoSmithKline Biologicals SA | Low-dose lyophilized rna vaccines and methods for preparing and using the same |
| US20240350410A1 (en) | 2021-08-16 | 2024-10-24 | Glaxosmithkline Biologicals Sa | Freeze-drying of lipid nanoparticles (lnps) encapsulating rna and formulations thereof |
| GB202303019D0 (en) | 2023-03-01 | 2023-04-12 | Glaxosmithkline Biologicals Sa | Method of lyophilisation |
| GB202311382D0 (en) | 2023-07-25 | 2023-09-06 | Glaxosmithkline Biologicals Sa | Lyophilised compostion |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0525213D0 (en) | 2005-12-12 | 2006-01-18 | Secr Defence | Vaccine |
-
2006
- 2006-10-25 EP EP06831828A patent/EP1954306A2/en not_active Withdrawn
- 2006-10-25 WO PCT/IB2006/003843 patent/WO2007049155A2/en not_active Ceased
- 2006-10-25 US US12/091,604 patent/US7776336B2/en not_active Expired - Fee Related
- 2006-10-25 JP JP2008537233A patent/JP2009515831A/ja active Pending
- 2006-10-25 CA CA002627302A patent/CA2627302A1/en not_active Abandoned
- 2006-10-25 AU AU2006307602A patent/AU2006307602A1/en not_active Abandoned
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