JP2009503072A - 退形成性神経膠腫に対する補助的化学療法 - Google Patents

退形成性神経膠腫に対する補助的化学療法 Download PDF

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Publication number
JP2009503072A
JP2009503072A JP2008525035A JP2008525035A JP2009503072A JP 2009503072 A JP2009503072 A JP 2009503072A JP 2008525035 A JP2008525035 A JP 2008525035A JP 2008525035 A JP2008525035 A JP 2008525035A JP 2009503072 A JP2009503072 A JP 2009503072A
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Japan
Prior art keywords
glioma
tert
pbn
butylnitrone
tumor
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JP2008525035A
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English (en)
Japanese (ja)
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JP2009503072A5 (https=
Inventor
レアル エー. タウナー
ヤシゲ コタケ
ロバート エー. フロイド
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Oklahoma Medical Research Foundation
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Oklahoma Medical Research Foundation
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Publication of JP2009503072A publication Critical patent/JP2009503072A/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7008Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
JP2008525035A 2005-08-04 2006-07-28 退形成性神経膠腫に対する補助的化学療法 Withdrawn JP2009503072A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US70572105P 2005-08-04 2005-08-04
PCT/US2006/029152 WO2007019065A2 (en) 2005-08-04 2006-07-28 Adjuvant chemotherapy for anaplastic gliomas

Publications (2)

Publication Number Publication Date
JP2009503072A true JP2009503072A (ja) 2009-01-29
JP2009503072A5 JP2009503072A5 (https=) 2009-09-10

Family

ID=37727837

Family Applications (1)

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JP2008525035A Withdrawn JP2009503072A (ja) 2005-08-04 2006-07-28 退形成性神経膠腫に対する補助的化学療法

Country Status (6)

Country Link
US (1) US20070032453A1 (https=)
EP (1) EP1922075A4 (https=)
JP (1) JP2009503072A (https=)
AU (1) AU2006278741A1 (https=)
CA (1) CA2617492A1 (https=)
WO (1) WO2007019065A2 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003262642B2 (en) 2002-08-14 2010-06-17 Vertex Pharmaceuticals Incorporated Protein kinase inhibitors and uses thereof
US7723301B2 (en) * 2007-08-29 2010-05-25 The Board Of Trustees Of The University Of Arkansas Pharmaceutical compositions comprising an anti-teratogenic compound and applications of the same
AU2009288057B2 (en) * 2008-09-02 2014-07-03 Oklahoma Medical Research Foundation 2, 4-disulfonyl pheny tert-butyl nitrone for the treatment of gliomas
JP5242651B2 (ja) * 2010-09-24 2013-07-24 株式会社東芝 レポーター遺伝子構築物、アッセイキットおよび検出方法
ES3063479T3 (en) 2017-09-20 2026-04-16 Oklahoma Med Res Found Treatment of drug resistant gliomas

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4928835A (en) * 1989-01-31 1990-05-29 Continental Pet Technologies, Inc. Injection molded preform, method of treating same and container formed therefrom
US5766909A (en) * 1992-02-04 1998-06-16 Merck & Co., Inc. DNA encoding inducible nitric oxide synthase
US5569902A (en) * 1995-01-17 1996-10-29 Welch Allyn, Inc. Contact two-dimensional bar code reader having pressure actuated switch
US5942385A (en) * 1996-03-21 1999-08-24 Sugen, Inc. Method for molecular diagnosis of tumor angiogenesis and metastasis
US6479481B1 (en) * 1999-06-04 2002-11-12 Ed. Geistlich Soehne Ag Fur Chemische Industrie Methods and compositions for treating primary and secondary tumors of the central nervous system (CNS)
JP2004500411A (ja) * 2000-03-30 2004-01-08 オクラホマ メディカル リサーチ ファウンデーション 癌の発達の阻害のための、ブチルニトロンを含む組成物
EP1525003A1 (en) * 2002-06-28 2005-04-27 Pharmacia Corporation Methods and contrast agents useful in quantifying nitric oxide

Also Published As

Publication number Publication date
WO2007019065A2 (en) 2007-02-15
WO2007019065A3 (en) 2007-11-15
EP1922075A4 (en) 2009-10-14
CA2617492A1 (en) 2007-02-15
EP1922075A2 (en) 2008-05-21
US20070032453A1 (en) 2007-02-08
AU2006278741A1 (en) 2007-02-15

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