JP2009501718A5 - - Google Patents
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- Publication number
- JP2009501718A5 JP2009501718A5 JP2008521632A JP2008521632A JP2009501718A5 JP 2009501718 A5 JP2009501718 A5 JP 2009501718A5 JP 2008521632 A JP2008521632 A JP 2008521632A JP 2008521632 A JP2008521632 A JP 2008521632A JP 2009501718 A5 JP2009501718 A5 JP 2009501718A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- composition according
- col
- antibacterial tetracycline
- clostridium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 23
- 230000000844 anti-bacterial effect Effects 0.000 claims 15
- 239000004098 Tetracycline Substances 0.000 claims 14
- 229960002180 tetracycline Drugs 0.000 claims 14
- 229930101283 tetracycline Natural products 0.000 claims 14
- 235000019364 tetracycline Nutrition 0.000 claims 14
- 150000003522 tetracyclines Chemical class 0.000 claims 12
- 241000894006 Bacteria Species 0.000 claims 4
- 241000124008 Mammalia Species 0.000 claims 3
- 210000004666 bacterial spore Anatomy 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 241000193830 Bacillus <bacterium> Species 0.000 claims 2
- 241000193403 Clostridium Species 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 230000002458 infectious effect Effects 0.000 claims 2
- -1 tetracycline compounds Chemical class 0.000 claims 2
- SGKRLCUYIXIAHR-AKNGSSGZSA-N (4s,4ar,5s,5ar,6r,12ar)-4-(dimethylamino)-1,5,10,11,12a-pentahydroxy-6-methyl-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical compound C1=CC=C2[C@H](C)[C@@H]([C@H](O)[C@@H]3[C@](C(O)=C(C(N)=O)C(=O)[C@H]3N(C)C)(O)C3=O)C3=C(O)C2=C1O SGKRLCUYIXIAHR-AKNGSSGZSA-N 0.000 claims 1
- FFTVPQUHLQBXQZ-KVUCHLLUSA-N (4s,4as,5ar,12ar)-4,7-bis(dimethylamino)-1,10,11,12a-tetrahydroxy-3,12-dioxo-4a,5,5a,6-tetrahydro-4h-tetracene-2-carboxamide Chemical group C1C2=C(N(C)C)C=CC(O)=C2C(O)=C2[C@@H]1C[C@H]1[C@H](N(C)C)C(=O)C(C(N)=O)=C(O)[C@@]1(O)C2=O FFTVPQUHLQBXQZ-KVUCHLLUSA-N 0.000 claims 1
- 241000193738 Bacillus anthracis Species 0.000 claims 1
- 241000193755 Bacillus cereus Species 0.000 claims 1
- 241000193163 Clostridioides difficile Species 0.000 claims 1
- 241000193155 Clostridium botulinum Species 0.000 claims 1
- 241000193468 Clostridium perfringens Species 0.000 claims 1
- 241000193449 Clostridium tetani Species 0.000 claims 1
- 241000193159 Hathewaya histolytica Species 0.000 claims 1
- 229940065181 bacillus anthracis Drugs 0.000 claims 1
- 230000001580 bacterial effect Effects 0.000 claims 1
- ZXFCRFYULUUSDW-OWXODZSWSA-N chembl2104970 Chemical group C([C@H]1C2)C3=CC=CC(O)=C3C(=O)C1=C(O)[C@@]1(O)[C@@H]2CC(O)=C(C(=O)N)C1=O ZXFCRFYULUUSDW-OWXODZSWSA-N 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 229960003722 doxycycline Drugs 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 229960004023 minocycline Drugs 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11/182,500 US20070015738A1 (en) | 2005-07-15 | 2005-07-15 | Use of non-antibacterial tetracycline formulations for inhibiting bacterial spores from becoming infectious vegetative cells |
| US11/317,635 US20070015739A1 (en) | 2005-07-15 | 2005-12-23 | Use of non-antibacterial tetracycline formulations for inhibiting bacterial spores |
| PCT/US2006/027313 WO2007011699A2 (en) | 2005-07-15 | 2006-07-14 | Use of non-antibacterial tetracycline formulations for inhibiting bacterial spores |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2009501718A JP2009501718A (ja) | 2009-01-22 |
| JP2009501718A5 true JP2009501718A5 (https=) | 2009-09-03 |
Family
ID=37662365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008521632A Pending JP2009501718A (ja) | 2005-07-15 | 2006-07-14 | 細菌胞子を抑制するための、非抗菌性のテトラサイクリン製剤の使用 |
Country Status (3)
| Country | Link |
|---|---|
| US (2) | US20070015738A1 (https=) |
| JP (1) | JP2009501718A (https=) |
| CN (1) | CN101460177A (https=) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL152486A0 (en) | 2002-10-25 | 2003-05-29 | Meir Eini | Alcohol-free cosmetic and pharmaceutical foam carrier |
| US9265725B2 (en) | 2002-10-25 | 2016-02-23 | Foamix Pharmaceuticals Ltd. | Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof |
| US7704518B2 (en) | 2003-08-04 | 2010-04-27 | Foamix, Ltd. | Foamable vehicle and pharmaceutical compositions thereof |
| US10117812B2 (en) | 2002-10-25 | 2018-11-06 | Foamix Pharmaceuticals Ltd. | Foamable composition combining a polar solvent and a hydrophobic carrier |
| ES2532906T5 (es) | 2002-10-25 | 2022-03-23 | Foamix Pharmaceuticals Ltd | Espuma cosmética y farmacéutica |
| US7700076B2 (en) | 2002-10-25 | 2010-04-20 | Foamix, Ltd. | Penetrating pharmaceutical foam |
| US20080138296A1 (en) | 2002-10-25 | 2008-06-12 | Foamix Ltd. | Foam prepared from nanoemulsions and uses |
| US9668972B2 (en) | 2002-10-25 | 2017-06-06 | Foamix Pharmaceuticals Ltd. | Nonsteroidal immunomodulating kit and composition and uses thereof |
| US20080260655A1 (en) | 2006-11-14 | 2008-10-23 | Dov Tamarkin | Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses |
| PL2109602T3 (pl) * | 2006-12-21 | 2014-09-30 | Paratek Pharm Innc | Pochodne tetracyliny do leczenia zakażeń bakteryjnych, wirusowych i pasożytniczych |
| US8636982B2 (en) | 2007-08-07 | 2014-01-28 | Foamix Ltd. | Wax foamable vehicle and pharmaceutical compositions thereof |
| US9439857B2 (en) | 2007-11-30 | 2016-09-13 | Foamix Pharmaceuticals Ltd. | Foam containing benzoyl peroxide |
| WO2009072007A2 (en) | 2007-12-07 | 2009-06-11 | Foamix Ltd. | Carriers, formulations, methods for formulating unstable active agents for external application and uses thereof |
| WO2010125470A2 (en) | 2009-04-28 | 2010-11-04 | Foamix Ltd. | Foamable vehicle and pharmaceutical compositions comprising aprotic polar solvents and uses thereof |
| CA2769677A1 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surface active agent non polymeric agent hydro-alcoholic foamable compositions, breakable foams and their uses |
| WO2011013009A2 (en) | 2009-07-29 | 2011-02-03 | Foamix Ltd. | Non surfactant hydro-alcoholic foamable compositions, breakable foams and their uses |
| WO2011064631A1 (en) | 2009-10-02 | 2011-06-03 | Foamix Ltd. | Surfactant-free, water-free, foamable compositions and breakable foams and their uses |
| US9849142B2 (en) | 2009-10-02 | 2017-12-26 | Foamix Pharmaceuticals Ltd. | Methods for accelerated return of skin integrity and for the treatment of impetigo |
| EP4108248B1 (en) * | 2013-03-29 | 2025-09-17 | Biomed Valley Discoveries, Inc. | C. novyi for the treatment of solid tumors in humans |
| US10363182B2 (en) * | 2014-07-14 | 2019-07-30 | Hill-Rom Services, Inc. | Patient control arm with phone dock and head of bed lockout |
| JP6491457B2 (ja) * | 2014-10-29 | 2019-03-27 | 株式会社ミルボン | エアゾール型毛髪処理組成物およびエアゾール製品 |
| WO2016145160A1 (en) * | 2015-03-10 | 2016-09-15 | Pride Mobility Products Corp. | Lift chair control device |
| CN105412076B (zh) * | 2015-11-10 | 2016-08-31 | 陈艳 | 化合物在制备治疗小儿腹泻的药物中的用途 |
| US10398641B2 (en) | 2016-09-08 | 2019-09-03 | Foamix Pharmaceuticals Ltd. | Compositions and methods for treating rosacea and acne |
| US20220175803A1 (en) * | 2019-04-04 | 2022-06-09 | Cmtx Biotech Inc. | Methods of treating charcot-marie-tooth disease |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6506740B1 (en) * | 1998-11-18 | 2003-01-14 | Robert A. Ashley | 4-dedimethylaminotetracycline derivatives |
| US6635676B2 (en) * | 1999-04-28 | 2003-10-21 | Regents Of The University Of Michigan | Non-toxic antimicrobial compositions and methods of use |
| US6506803B1 (en) * | 1999-04-28 | 2003-01-14 | Regents Of The University Of Michigan | Methods of preventing and treating microbial infections |
| US6559189B2 (en) * | 1999-04-28 | 2003-05-06 | Regents Of The University Of Michigan | Non-toxic antimicrobial compositions and methods of use |
| US6589771B1 (en) * | 1999-10-28 | 2003-07-08 | Immunom Technologies, Inc. | Methods for arousing dormant bacteria |
| WO2003082011A1 (en) * | 2002-03-29 | 2003-10-09 | The Research Foundation Of State University Of New York | Use of non-antibacterial tetracycline analogs and formulations thereof for the treatment of bacterial exotoxins |
-
2005
- 2005-07-15 US US11/182,500 patent/US20070015738A1/en not_active Abandoned
- 2005-12-23 US US11/317,635 patent/US20070015739A1/en not_active Abandoned
-
2006
- 2006-07-14 JP JP2008521632A patent/JP2009501718A/ja active Pending
- 2006-07-14 CN CNA2006800256100A patent/CN101460177A/zh active Pending
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