JP2009291187A - Food composition for improving eating habit - Google Patents

Food composition for improving eating habit Download PDF

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JP2009291187A
JP2009291187A JP2008272707A JP2008272707A JP2009291187A JP 2009291187 A JP2009291187 A JP 2009291187A JP 2008272707 A JP2008272707 A JP 2008272707A JP 2008272707 A JP2008272707 A JP 2008272707A JP 2009291187 A JP2009291187 A JP 2009291187A
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rice bran
composition
defatted
eating habits
food composition
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Ren Kawase
漣 川瀬
Sumie Okamura
寿美恵 岡村
Shoji Asami
章治 阿左美
Nobuaki Maeda
宜昭 前田
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Sunstar Inc
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Abstract

<P>PROBLEM TO BE SOLVED: To provide a food composition for improving eating habits, which is made by mixing a defatted rice bran obtained by compressing rice bran with a purified rice bran oil in a specific ratio. <P>SOLUTION: The food composition for improving eating habits comprises a defatted rice bran obtained by compressing rice bran and a purified rice bran oil in a weight ratio of both the contents of 85:15 to 60:40. Preferably the composition for improving eating habits comprises a rice bran-like composition composed of a weight ratio of a defatted rice bran to a purified rice bran oil of 85:15 to 60:40. Consequently, since excellent effects such as suppression of the increase of and reduction of, visceral fat, suppression of the increase of and reduction of, triglyceride in blood, suppression of the increase of and reduction of, blood sugar level, the effect of reducing oxidative damage of the living body, magnesium the effect of retaining in the body are obtained, the composition is used as foods for improving eating habits for the purpose of preventing and ameliorating obesity, diabetes, lipid abnormal disease, hypertension, arteriosclerosis, liver disease and respiratory disease, ameliorating insulin resistance, preventing aging and preventing a reduction in the adiponectin secretion amount. <P>COPYRIGHT: (C)2010,JPO&INPIT

Description

本発明は、米糠を圧搾処理した脱脂米糠、及び精製米糠油を特定の重量比率で含有することを特徴とする食生活改善用食品組成物に関する。   The present invention relates to a food composition for improving eating habits characterized by containing defatted rice bran obtained by pressing rice bran and refined rice bran oil in a specific weight ratio.

生活習慣病である肥満、糖尿病,脂質異常症,高血圧、動脈硬化などを予防や治療するために、個々の疾患に対して個別に対処されている。しかし、これらの疾患を有する患者は、複数の生活習慣病を罹患している場合が殆どであり、またそれらの疾患は相互に複雑な関係を有していることが知られつつある。そのため、個々の疾患に対する個別の対処では十分な治療効果が得ることができていない。   Individual diseases are individually addressed to prevent and treat lifestyle-related diseases such as obesity, diabetes, dyslipidemia, hypertension, and arteriosclerosis. However, patients with these diseases are mostly suffering from multiple lifestyle-related diseases, and these diseases are becoming known to have a complex relationship with each other. Therefore, a sufficient therapeutic effect cannot be obtained by individual treatment for each disease.

近年、「内臓脂肪(以下、「腸間膜脂肪」ということがある。)」の増加と様々な生活習慣病と関係が明らかになりつつある。そこで、「内臓脂肪」に着眼し、様々な生活習慣病を包含したメタボリックシンドロームという新しい概念が提唱されている。   In recent years, the relationship between an increase in “visceral fat (hereinafter sometimes referred to as“ mesenteric fat ”)” and various lifestyle-related diseases is becoming clear. Therefore, a new concept called metabolic syndrome has been proposed that focuses on “visceral fat” and encompasses various lifestyle-related diseases.

メタボリックシンドロームとは、「内臓脂肪の蓄積」に加えて、内臓脂肪蓄積をリスク要因に有する「血糖」、「脂質代謝」や「血圧」の状態を把握し、動脈硬化のリスクが高い病態として定義するものである。この概念によれば「内臓脂肪」を低減することで様々な生活習慣病の予防や治療が可能となることから、日本において、2008年4月からメタボリックシンドロームの診断を目的とした特定検診が実施され、メタボリックシンドロームに罹患する可能性のある人や罹患している人を見出す試みがなされている。   Metabolic syndrome is defined as a pathological condition with a high risk of arteriosclerosis by grasping the status of "blood sugar", "lipid metabolism" and "blood pressure" that have visceral fat accumulation as a risk factor in addition to "visceral fat accumulation" To do. According to this concept, it is possible to prevent and treat various lifestyle-related diseases by reducing “visceral fat”. In April 2008, a specific screening for the diagnosis of metabolic syndrome has been conducted in Japan. Attempts have been made to find out who may or may be affected by metabolic syndrome.

上記特定検診で見出された人に対する対処としては、食事指導や運動指導などを行い、投薬治療をできる限り避けることとされている。しかし、従前の食事指導や運動指導を実生活において遵守することは困難なことが多い。そこで、日常生活で無理なく摂取でき、上記効果を有する食生活改善用食品の開発が進められているが、未だ十分な効果を有する食品は得られておらず、早期の開発が望まれている。   As a countermeasure for the person found by the specific examination, dietary guidance and exercise guidance are performed, and medication treatment is avoided as much as possible. However, it is often difficult to observe the conventional dietary guidance and exercise guidance in real life. Therefore, the development of foods for improving dietary habits that can be taken comfortably in daily life and has the above effects has been promoted, but foods having sufficient effects have not yet been obtained, and early development is desired. .

一方、米糠は、米の果皮、種皮、外胚乳、糊粉層等であり、玄米に約10重量%含まれている。油分、タンパク質、無機質、ビタミンB群(特にB1)が豊富であることが知られており、飼料や農業分野での利用のほか、米糠油やフィチン酸やイノシトールなどの製造原料として活用されているが、機能性食品への応用としては、米糠の搾油後の残渣である脱脂米糠を粉末状に加工して栄養強化用の食品添加剤として利用する提案がなされているだけである。(例えば特許文献1参照)
特開2007−104962号公報
On the other hand, rice bran is rice pericarp, seed coat, outer endosperm, paste layer, etc., and is contained in brown rice by about 10% by weight. It is known to be rich in oils, proteins, minerals, and vitamin B groups (especially B 1 ). In addition to its use in feed and agriculture, it is used as a raw material for production of rice bran oil, phytic acid, inositol, etc. However, as an application to functional foods, only proposals have been made to process defatted rice bran, which is a residue after squeezing rice bran, into a powder form and use it as a food additive for enhancing nutrition. (For example, see Patent Document 1)
JP 2007-104962 A

本発明は、脱脂米糠及び精製米糠油を、特定比率で配合したことを特徴とする食生活改善用食品組成物の提供を目的とする。   An object of the present invention is to provide a food composition for improving eating habits, characterized by blending defatted rice bran and refined rice bran oil in a specific ratio.

本発明者は、米糠を圧搾法で搾油処理した脱脂米糠と、精製した米糠油とを重量比で85:15〜60:40を含有する食生活改善用食品組成物が、「体内の抗酸化効果」、「内臓脂肪の増加を抑制する効果」、「血清トリグリセリド値の低下効果」および「空腹時の血糖値の増加を抑制する効果」に優れることを見出し、本発明を完成させた。   The present inventor has proposed that a food composition for improving eating habits containing 85:15 to 60:40 in weight ratio of defatted rice bran obtained by squeezing rice bran by a pressing method and “refined rice bran oil” by weight ratio. The present inventors have found that it is excellent in “effect”, “effect of suppressing increase in visceral fat”, “effect of reducing serum triglyceride level” and “effect of suppressing increase in blood glucose level during fasting”, and completed the present invention.

すなわち、本発明は下記の食生活改善用食品組成物を提供するものである。
項1.米糠を圧搾処理した脱脂米糠及び精製米糠油を、それぞれの含量が重量比で85:15〜60:40となるように含有することを特徴とする食生活改善用食品組成物。
項2. メタボリックシンドロームの予防または改善のために使用するものであることを特徴とする項1に記載の食生活改善用食品組成物。
項3.脱脂米糠及び精製米糠油の重量比が85:15〜60:40となるように予め含有させた米糠様組成物を製造し、該米糠様組成物を配合することを特徴とする項1もしくは項2に記載の食生活改善用食品組成物。
That is, the present invention provides the following food composition for improving eating habits.
Item 1. A food composition for improving eating habits, comprising defatted rice bran obtained by pressing rice bran and refined rice bran oil so that each content is 85:15 to 60:40 by weight.
Item 2. The food composition for improving eating habits according to Item 1, which is used for prevention or improvement of metabolic syndrome.
Item 3. A rice bran-like composition containing a defatted rice bran and a refined rice bran oil in a weight ratio of 85:15 to 60:40 is produced, and the rice bran-like composition is blended. Item 3. A food composition for improving eating habits according to Item 1 or Item 2.

本発明に使用する脱脂米糠は、搗精後に得られた米糠(生米糠)をリパーゼ失活処理し、圧搾処理した後の、脂質含量が5〜12重量%の残渣である。有機溶媒を用いて脱脂された脱脂米糠は、有用成分が除去される可能性が高いため好ましくない。リパーゼ失活処理は、通常18〜20重量%程度の脂質を含有する米糠(生米糠)の酸化劣化を防ぐ目的で行われ、通常、生米糠を70〜130℃程度で加熱焙煎することにより行われる。圧搾処理は、公知の圧搾法、例えば加熱焙煎処理され100〜115℃程度になった米糠を低温連続圧搾機(例えば(株)テクノシグマ社より販売されているミラクルチャンバー)により圧搾することで行う。圧搾は、圧搾後の脱脂米糠中の脂質が5〜15重量%程度となるまで行う。また、リパーゼ失活処理前の米糠や搾油後の脱脂米糠の水分含量を低減させる乾燥処理を行っても良い。更に、脱脂米糠は、公知の方法により粉砕、分級し粉末状とすることが好ましい。この際、粉末の平均粒子径は、5〜200μmが好ましく、10〜150μmがより好ましく、40〜100μmが最も好ましい。なお、脱脂米糠中の脂質は、5〜20重量%が好ましく、7〜15重量%がより好ましい。   The defatted rice bran used in the present invention is a residue having a lipid content of 5 to 12% by weight after lipase deactivation treatment and pressing treatment of rice bran (raw rice bran) obtained after milling. A defatted rice bran defatted using an organic solvent is not preferred because it is highly likely that useful components will be removed. The lipase inactivation treatment is usually performed for the purpose of preventing oxidative degradation of rice bran (raw rice bran) containing about 18 to 20% by weight of lipid. Usually, the raw rice bran is heated and roasted at about 70 to 130 ° C. Done. The pressing process is performed by pressing a rice bran that has been heated and roasted to about 100 to 115 ° C. with a low-temperature continuous pressing machine (for example, a miracle chamber sold by Techno-Sigma Co., Ltd.). Do. The pressing is performed until the lipid in the defatted rice bran after pressing is about 5 to 15% by weight. Moreover, you may perform the drying process which reduces the water content of the rice bran before a lipase inactivation process, and the defatted rice bran after oil extraction. Furthermore, the defatted rice bran is preferably pulverized and classified by a known method to form a powder. At this time, the average particle size of the powder is preferably 5 to 200 μm, more preferably 10 to 150 μm, and most preferably 40 to 100 μm. In addition, 5-20 weight% is preferable and, as for the lipid in defatted rice bran, 7-15 weight% is more preferable.

本発明に使用する精製米糠油は、米糠原油は圧搾法により得られた米糠原油を公知の方法で精製した後の、ロウ分が0.5重量%以下、遊離脂肪酸が5重量%以下の米糠油であり、好ましくは、ロウ分が0.1重量%以下、遊離脂肪酸が1重量%以下の精製米糠油である。圧搾により得られた米糠原油には、通常、ロウ分が約3重量%、遊離脂肪酸が約30重量%含まれるため、公知の方法を用いて精製を行う。精製法としてはスチームリファイニング工程を含むものが好ましい。   The refined rice bran oil used in the present invention is a rice bran having a wax content of 0.5% by weight or less and a free fatty acid of 5% by weight or less after refining a rice bran crude oil obtained by a compression method using a known method. Oil, preferably refined rice bran oil having a wax content of 0.1% by weight or less and a free fatty acid of 1% by weight or less. The rice bran crude oil obtained by pressing usually contains about 3% by weight of wax and about 30% by weight of free fatty acid, and thus is refined using a known method. A purification method including a steam refining step is preferable.

本発明の食生活改善用食品組成物は、前記の脱脂米糠と精製米糠油を特定の重量比率で配合し、公知の方法を用いて製造する。脱脂米糠と精製米糠油の含有重量比率は、85:15〜60:40(脱脂米糠:精製米糠油)であり、好ましくは80:20〜70:30である。好ましい食生活改善用食品組成物としては、水分2〜8重量%、脂質30〜40重量%、ロウ分0.6重量%以下、遊離脂肪酸0.5〜3.5重量%の成分含量を示す。また、該食品組成物への脱脂米糠および精製米糠油の含有量は、それぞれ4〜85重量%および1〜40重量%である。   The food composition for improving eating habits of the present invention is produced by blending the defatted rice bran and purified rice bran oil in a specific weight ratio and using a known method. The content weight ratio of defatted rice bran and refined rice bran oil is 85: 15-60: 40 (defatted rice bran: refined rice bran oil), preferably 80: 20-70: 30. A preferred food composition for improving eating habits has a component content of 2 to 8% by weight of water, 30 to 40% by weight of lipid, 0.6% by weight or less of wax, and 0.5 to 3.5% by weight of free fatty acids. . The contents of defatted rice bran and refined rice bran oil in the food composition are 4 to 85% by weight and 1 to 40% by weight, respectively.

さらに、脱脂米糠と精製米糠油は、予め混合物(以下、「米糠様組成物」という。)とした後に、食生活改善用食品組成物へ配合することが好ましい。米糠様組成物中の脱脂米糠及び精製米糠油の含有比率は、それぞれ85:15〜60:40、好ましくは80:20〜70:30である。さらに、米糠様組成物には、脱脂米糠や精製米糠油以外の成分も混合しても良い。また、食生活改善用食品組成物への米糠様組成物の含有量は、5〜100重量%である。   Furthermore, it is preferable that the defatted rice bran and the refined rice bran oil are mixed in advance (hereinafter referred to as “rice bran-like composition”) and then blended into the food composition for improving eating habits. The content ratio of defatted rice bran and refined rice bran oil in the rice bran-like composition is 85: 15-60: 40, preferably 80: 20-70: 30, respectively. Furthermore, components other than defatted rice bran and refined rice bran oil may be mixed in the rice bran-like composition. Moreover, content of the rice bran-like composition in the food composition for improving eating habits is 5 to 100% by weight.

本発明の食生活改善用食品組成物は、特に限定はされないが、一般食品、栄養補助食品、機能性食品、特定保健用食品、病者用食品などとして使用される。具体的には、使用目的等に応じて、錠剤、顆粒、細粒、粉体、タブレット、カプセル、液体、ペースト、ゲルなどの剤型とできる。具体的には、サプリメント、トローチ、飲料、飴、グミ、クッキー、米菓、ケーキ、パン、麺類、シリアル、シリアルバー、スープ、レトルト食品、ドレッシング、米飯用添加剤、料理用原料などが挙げられる。   The food composition for improving eating habits of the present invention is not particularly limited, but is used as a general food, a nutritional supplement, a functional food, a food for specified health use, a food for a sick person, and the like. Specifically, depending on the purpose of use, it can be made into dosage forms such as tablets, granules, fine granules, powders, tablets, capsules, liquids, pastes and gels. Specific examples include supplements, troches, beverages, rice cakes, gummi, cookies, rice cakes, cakes, bread, noodles, cereals, cereal bars, soups, retort foods, dressings, cooked rice additives, cooking ingredients, etc. .

わが国においては、「過剰な内臓脂肪の蓄積」に加えて、「空腹時血糖値」、「血清中のトリグセリド値またはHDLコレステロール値」、「血圧値」の3項目のうち2項目以上が規定値を外れた場合、メタボリックシンドロームと診断している。本発明の食品組成物は、「内臓脂肪の増加を抑制する効果」に加え、「空腹時の血糖値の増加を抑制する効果」、「血清トリグリセリド値の低下効果」および「体内の抗酸化効果」に優れていることから、肥満、糖尿病,脂質異常症,高血圧、動脈硬化、肝疾患、呼吸器疾患の予防や改善、インスリン抵抗性の改善、老化防止、アディポネクチン分泌量の低減防止の目的で食生活改善用食品として使用できる。特に、体内の抗酸化効果に優れていることから、メタボリックシンドロームや動脈硬化の予防または改善用としての使用が期待できる。   In Japan, in addition to “excessive visceral fat accumulation”, two or more of the three items of “fasting blood glucose level”, “serum triglyceride level or HDL cholesterol level”, and “blood pressure level” are specified values. If it is outside the range, it is diagnosed as metabolic syndrome. The food composition of the present invention includes, in addition to the “inhibitory effect on the increase in visceral fat”, the “inhibition effect on the increase in fasting blood glucose level”, the “lowering effect on serum triglyceride level”, and the “antioxidant effect in the body” For the purpose of obesity, diabetes, dyslipidemia, high blood pressure, arteriosclerosis, liver disease, respiratory disease, improvement of insulin resistance, prevention of aging, reduction of adiponectin secretion It can be used as a food for improving eating habits. In particular, since it has an excellent antioxidant effect in the body, it can be expected to be used for prevention or improvement of metabolic syndrome and arteriosclerosis.

本発明の食生活改善用食品組成物は、血中の中性脂肪が気になる人、血中コレステロールが気になる人、血糖値が気になる人、動脈硬化が気になる人、肝機能が気になる人、心疾患が気になる人、腹部肥満が気になる人、喫煙する人、脂肪の多い食事をとりがちな人、外食の多い人、肉類及び乳製品を多く食べる人、加工食品を多く食べる人などを対象とした食品や、糖尿病、高血圧、動脈硬化、脂質異常症、肥満を有する人やそれらの境界域に属する人のための食生活改善用食品などとすることができる。   The food composition for improving dietary habits of the present invention includes a person concerned about blood neutral fat, a person concerned about blood cholesterol, a person concerned about blood glucose level, a person concerned about arteriosclerosis, liver Person who is worried about function, person who is worried about heart disease, person who is worried about abdominal obesity, person who smokes, person who tends to eat fat meal, person who eats a lot, person who eats many meat and dairy products Foods intended for people who eat a lot of processed foods, foods for improving eating habits for people with diabetes, hypertension, arteriosclerosis, dyslipidemia, obesity and those who are in their borders Can do.

以下、試験例、実施例により本発明をより詳細に説明するが、本発明はこれらに限定されるものではない。   EXAMPLES Hereinafter, although this invention is demonstrated in detail by a test example and an Example, this invention is not limited to these.

<試験例1;高脂肪食を摂食させたラットの体内脂肪量、血中のトリグリセリド量>
高脂肪食の摂取が及ぼす影響とその影響に対する本発明の食生活改善用食品組成物の作用をラットにより試験した。
4週齢のSD系雄ラットを、1試験群6匹に群分けし、試験に供した。
飼育環境は、ステンレス製6連ゲージを使用し、気温24±1℃、湿度55±5%、8時から20時までの12時間の照明点灯条件とした。
飼料は下記表1に示された組成の標準食(Cont.)、高脂肪精白米食(WR)(以下、「精白米食」ともいう。)、高脂肪玄米食(BR)(以下、「玄米食」ともいう。)、高脂肪試験食(高脂肪精白米及び図1のプロセスにより製造した米糠様組成物(脱脂米糠及び精製米糠油の重量比75:25))(以下、「試験食」とも言う。)(WR+RP)とした。
なお、標準食以外の飼料は、標準食の大豆油の代わりにラード(豚背脂)を配合し、αコーンスターチの代わりに、α精白米粉末、α玄米粉末、α精白米粉末及び米糠様組成物(精白米及び米糠様組成物の重量比9:1)に代えた高脂肪食である。
<Test Example 1; body fat content and blood triglyceride content of rats fed a high fat diet>
The effect of the intake of a high fat diet and the effect of the food composition for improving dietary habits of the present invention on the effect were tested in rats.
Four-week-old SD male rats were grouped into 6 test groups and subjected to the test.
The breeding environment was a stainless steel 6 gauge, temperature 24 ± 1 ° C., humidity 55 ± 5%, and lighting conditions for 12 hours from 8:00 to 20:00.
The feed is a standard diet (Cont.), High-fat polished rice (WR) (hereinafter also referred to as “refined rice”), high-fat brown rice (BR) (hereinafter referred to as “brown rice”). ), High-fat test meal (high-fat polished rice and rice bran-like composition produced by the process of FIG. 1 (weight ratio of defatted rice bran and refined rice bran oil 75:25)) (hereinafter also referred to as “test meal”) Say) (WR + RP).
In addition, feed other than the standard meal contains lard (pig back fat) instead of soybean oil of the standard meal, and instead of α corn starch, α refined rice powder, α brown rice powder, α refined rice powder and rice bran-like composition It is a high-fat meal in place of the product (weight ratio of polished rice and rice bran-like composition 9: 1).

Figure 2009291187
Figure 2009291187

また、これらの栄養成分の分析値(水分含量、粗たんぱく質含量、粗脂肪含量、炭水化物含量、粗灰分含量)を下記表2に示す。   The analytical values (water content, crude protein content, crude fat content, carbohydrate content, crude ash content) of these nutritional components are shown in Table 2 below.

Figure 2009291187
Figure 2009291187

測定結果を図2〜5に示す。初体重(図2左上)、終体重(図2右上)、飼料摂取量(図2左下)、総脂肪率(図2右下)体内脂肪量(腸間膜(図3左)、後腹壁(図3右))血中のトリグリセリド量(図4)CM(カイロミクロン)分画におけるトリグリセリド量(図5左上)、VLDL分画におけるトリグリセリド量(図5右上)、LDL分画におけるトリグリセリド量(図5左下)、HDL分画におけるトリグリセリド量(図5右下)。   The measurement results are shown in FIGS. Initial body weight (upper left of FIG. 2), final body weight (upper right of FIG. 2), feed intake (lower left of FIG. 2), total fat percentage (lower right of FIG. 2) body fat mass (mesentery (left of FIG. 3), retroabdominal wall ( Fig. 3 right)) Triglyceride level in blood (Fig. 4) Triglyceride level in CM (chylomicron) fraction (upper left in Fig. 5), Triglyceride level in VLDL fraction (upper right in Fig. 5), Triglyceride level in LDL fraction (Fig. 5 lower left), the amount of triglycerides in the HDL fraction (lower right of FIG. 5).

<体内脂肪量>
試験食群(WR+RP)は、精白米食群(WR)と比較して腸間膜脂肪量が著しく少なかった。その程度は、玄米食群(BR)より明らかに大きく、標準食群(Cont.)と同程度であった。
<Body fat content>
The test meal group (WR + RP) had significantly less mesenteric fat than the polished rice meal group (WR). The degree was clearly larger than that of the brown rice group (BR) and the same level as that of the standard group (Cont.).

<血中トリグリセリド量>
高脂肪試験食群(WR+RP)は、標準食群(Cont.)や高脂肪精白米食群(WR)と比較して約2分の1であり、高脂肪玄米食群(BR)と比較しても大幅に低くかった。
<Blood triglyceride level>
The high-fat test meal group (WR + RP) is about a half of the standard meal group (Cont.) And the high-fat polished rice meal group (WR), compared with the high-fat brown rice meal group (BR). But it was much lower.

<各分画における中性脂肪量>
CM分画とVLDL分画において血中のトリグリセリド量と同じ傾向であり、試験食群(WR+RP)はいずれの画分においても玄米食(BR)よりも低かった。
<Amount of neutral fat in each fraction>
The CM fraction and the VLDL fraction had the same tendency as the blood triglyceride amount, and the test meal group (WR + RP) was lower than the brown rice meal (BR) in any fraction.

<試験例2;高脂肪食を摂食させたラットのマグネシウムの吸収・排泄動態>
試験例1における高脂肪精白米食(WR)、高脂肪玄米食(BR)、高脂肪試験食(WR+RP)の各群におけるマグネシウムの吸収・排泄動態を試験した。マグネシウムの定量方法は公知の方法を使用した。ラットの個体ごとに、摂食した餌の量を精確に計量することでマグネシウム摂取総量(M1)を求め、排泄物を全て回収し、尿と糞に含まれるマグネシウムを定量することでマグネシウム排泄総量(M2)を求め、これらの結果より下記の数式1に従って体内保留率(M3)を算出し、各群を比較した。結果を表3に示す。
<Test Example 2: Absorption and excretion dynamics of magnesium in rats fed a high fat diet>
The absorption and excretion kinetics of magnesium in each group of high-fat refined rice meal (WR), high-fat brown rice meal (BR), and high-fat test meal (WR + RP) in Test Example 1 were tested. A known method was used for the determination of magnesium. For each rat, accurately measure the amount of food consumed to determine the total amount of magnesium intake (M1), collect all excreta, and determine the amount of magnesium contained in urine and feces to determine the total amount of magnesium excreted. (M2) was calculated, and the in-vivo retention rate (M3) was calculated from these results according to the following formula 1, and each group was compared. The results are shown in Table 3.

Figure 2009291187
Figure 2009291187

Figure 2009291187
Figure 2009291187

表3に示したとおり、同じマグネシウムを含有する高脂肪試験食と高脂肪玄米食を比較すると、高脂肪試験食のほうが優れたマグネシウムの体内保留率を示した。   As shown in Table 3, when the high-fat test meal containing the same magnesium and the high-fat brown rice meal were compared, the high-fat test meal showed a superior magnesium retention rate.

<試験例3;自然発症糖尿病マウスにおける血糖値、血中の抗酸化指標値>
自然発症糖尿病マウスに対する本発明の食生活改善用食品組成物の抗糖尿病
作用を試験した。
試験は、標準食にて自然発症糖尿病マウス(KKAt/TA)を1週間予備飼育した後、各飼料により4週間の本飼育を行った。なお、飼料は自由摂取とし、給水も蒸留水を自由摂取とした。空腹時の血糖値については、試験開始時、2週間飼育時、飼育終了時(4週間飼育時)の3回測定し、血中の抗酸化指標としての8―OHdGとイソプロスタンについては、試験開始時と飼育終了時(4週間飼育時)の2回測定し、その他の項目については、本飼育終了時(4週間飼育時)のみ測定した。
飼料は下記表4に示された組成の標準食(Cont.)、通常精白米食(WR2)、通常玄米食(BR2)、通常試験食(精白米及び図1のプロセスにより製造した米糠様組成物(脱脂米糠及び精製米糠油の重量比75:25))(WR2+RP)とした。
<Test Example 3; blood glucose level and blood antioxidant index value in spontaneously diabetic mice>
The antidiabetic action of the food composition for improving dietary habits of the present invention on spontaneously diabetic mice was tested.
In the test, spontaneously diabetic mice (KKAt / TA) were preliminarily bred for 1 week on a standard diet, and then main bred for 4 weeks with each feed. In addition, feed was freely ingested and distilled water was freely ingested. The fasting blood glucose level was measured three times at the start of the test, at the time of breeding for 2 weeks, and at the end of the breeding (at the time of breeding for 4 weeks). For 8-OHdG and isoprostane as blood antioxidant indicators, The measurement was made twice at the start and at the end of breeding (at the time of breeding for 4 weeks), and other items were measured only at the end of the breeding (at the time of breeding for 4 weeks).
The feed is a standard diet (Cont.), A regular polished rice diet (WR2), a regular brown rice diet (BR2), a normal test diet (milled rice and a rice bran-like composition produced by the process of FIG. (Weight ratio of defatted rice bran and refined rice bran oil 75:25)) (WR2 + RP).

Figure 2009291187
Figure 2009291187

<空腹時の血糖値>
飼育期間の終了時(4週間飼育時)において、通常試験食群(WR2+RP)は、標準食群(Cont.)および通常精白米食群(WR2)と比較して大幅に低く、試験開始時とほぼ同水準であった。
<Fast blood glucose level>
At the end of the breeding period (4 weeks of breeding), the normal test food group (WR2 + RP) was significantly lower than the standard food group (Cont.) And the normal polished rice food group (WR2), at the start of the test. And almost the same level.

<血中の抗酸化指標値>
脂質過酸化状態の指標であるイソプロスタン、DNAの酸化障害の指標である8―OHdGともに、通常試験食群(WR2+RB)は、標準食群(Cont.)、通常精白米食群(WR2)、通常玄米食群(BR2)の何れと比較しても大幅に低く、試験開始時と同水準であった。
<Antioxidation index value in blood>
The normal test food group (WR2 + RB) is the standard food group (Cont.) And the normal polished rice food group (WR2), both of which are isoprostan, which is an index of lipid peroxidation status, and 8-OHdG, which is an index of DNA oxidative damage. Compared with any of the normal brown rice group (BR2), the level was much lower than that at the start of the test.

測定結果を図6〜8に示す。初体重(図6左上)、終体重(図6右上)、飼料摂取量(図6左下)、空腹時の血糖値(図7)血中の8−OHdG量(図8右)血中のイソプロプタン量(図8左)   The measurement results are shown in FIGS. Initial body weight (upper left of FIG. 6), final body weight (upper right of FIG. 6), feed intake (lower left of FIG. 6), fasting blood glucose level (FIG. 7) 8-OHdG level in blood (right side of FIG. 8) isoproptan in blood Amount (Figure 8 left)

以上の試験により、試験食は他の群と比較して優れた「内臓脂肪の増加を抑制する効果」、「血中のトリグリセリド値の低下効果」及び「マグネシウム体内保留率」が確認できた。また、通常試験食は通常食、精白米食および玄米食と比較して、優れた「体内の抗酸化効果」および「空腹時の血糖値の増加を抑制する効果」があることが確認できた。玄米は、精白米と米糠から構成されていることから、試験食に用いた本発明の食生活改善用食品組成物は、米糠と比較して優れた上記の効果を有すると考えられる。従って、肥満、糖尿病,脂質異常症,高血圧、動脈硬化、肝疾患、呼吸器疾患の予防や改善、インスリン抵抗性の改善、老化防止、アジポネクチン分泌量の低減防止を目的とする食生活改善用食品としての使用が期待できる。   From the above tests, the test food was able to confirm superior “effect of suppressing increase in visceral fat”, “effect of reducing blood triglyceride level”, and “magnesium retention rate” in comparison with other groups. In addition, it was confirmed that the normal test meal had an excellent “antioxidant effect in the body” and “an effect of suppressing an increase in fasting blood glucose level” compared to the normal meal, polished rice meal and brown rice meal. Since brown rice is comprised of polished rice and rice bran, it is considered that the food composition for improving dietary habits of the present invention used for the test meal has the above-described effects superior to rice bran. Therefore, dietary foods for the purpose of preventing or improving obesity, diabetes, dyslipidemia, hypertension, arteriosclerosis, liver disease, respiratory diseases, improving insulin resistance, preventing aging, and reducing adiponectin secretion Can be used as

下記原料を使用して常法により食生活改善用食品組成物を製造した。なお、「%」は「重量%」を意味する。   A food composition for improving eating habits was produced by the conventional method using the following raw materials. “%” Means “% by weight”.

実施例1
顆粒状食品を下記にしたがって製造した。
1.脱脂米糠
米糠(生米糠)を70〜130℃程度で加熱してリパーゼ失活処理を行った。その後、ミラクルチャンバーを用いて、脱脂米糠の脂質含量が約10重量%程度になるまで低温圧搾処理を行ない、得られた脱脂米糠を、粉砕・分級し、平均粒径が約100μmの粉末状脱脂米糠とした。
2.精製米糠油
上記で得られた米糠原油をろ過した後に、脱ガム、脱ロウ、脱酸、脱色、脱臭の処理を加えて精製し、ロウ含量0.1重量%及び遊離脂肪酸含量0.9重量%の精製米糠油とした。
3. 食生活改善用食品組成物の製造
上記の粉末状脱脂米糠45重量%、精製米糠油15重量%、粉末マルチトール20重量%、難消化性デキストリン10重量%、ココアパウダー9重量%、粉末香料1重量%を混合し、常法により造粒加工することで顆粒状の生活改善用用食品組成物を製造した。
Example 1
Granular food was produced according to the following.
1. A lipase deactivation treatment was performed by heating a defatted rice bran rice bran (raw rice bran) at about 70 to 130 ° C. Then, using a miracle chamber, low-temperature pressing treatment is performed until the lipid content of the defatted rice bran reaches about 10% by weight, and the obtained defatted rice bran is pulverized and classified to a powdery defatted powder having an average particle size of about 100 μm. Rice bran.
2. Refined rice bran oil After filtering the rice bran crude oil obtained above, it is refined by adding degumming, dewaxing, deoxidation, decolorization, and deodorizing treatment to a wax content of 0.1% by weight and a free fatty acid content of 0.9% by weight. % Refined rice bran oil.
3. Production of food composition for improving eating habits Powdered defatted rice bran 45% by weight, refined rice bran oil 15% by weight, powdered maltitol 20% by weight, indigestible dextrin 10% by weight, cocoa powder 9% by weight, powder A granular food composition for life improvement was produced by mixing 1% by weight of a fragrance and granulating it by a conventional method.

実施例2
常法に従い、下記の玄米ふりかけを製造した。
成分 (重量%)
米糠様組成物(顆粒) 60%
(脱脂米糠 48%)
(精製米糠油 12%)
赤紫蘇 25%
黒ごまペースト(脂質60%) 10%
グルタミン酸ソーダ 5%
合計 100%
Example 2
According to a conventional method, the following brown rice sprinkles were produced.
Ingredient (wt%)
Rice bran-like composition (granule) 60%
(48% defatted rice bran)
(Refined rice bran oil 12%)
Red purple 25%
Black sesame paste (lipid 60%) 10%
Sodium glutamate 5%
Total 100%

実施例3
常法に従い、下記の粉末玄米飲料を製造した。
成分 (重量%)
米糠様組成物(顆粒) 30%
(脱脂米糠 21%)
(精製米糠油 9%)
黒ごまペースト(脂質60%) 15%
大豆パウダー 47%
粉末黒糖 8%
合計 100%
Example 3
In accordance with a conventional method, the following powdered brown rice beverage was produced.
Ingredient (wt%)
Rice bran-like composition (granule) 30%
(21% defatted rice bran)
(Refined rice bran oil 9%)
Black sesame paste (60% fat) 15%
Soy powder 47%
Powdered brown sugar 8%
Total 100%

実施例4
常法に従い、下記のタブレットを製造した。
成分 (重量%)
米糠様組成物(粉体) 20%
(脱脂米糠 17%)
(精製米糠油 3%)
マルチトール 38%
乳糖 30%
ショ糖脂肪酸エステル 5%
ステアリン酸カルシウム 4%
二酸化ケイ素 2%
粉末香料 1%
合計 100%
Example 4
The following tablets were produced according to a conventional method.
Ingredient (wt%)
Rice bran-like composition (powder) 20%
(17% defatted rice bran)
(Refined rice bran oil 3%)
Maltitol 38%
Lactose 30%
Sucrose fatty acid ester 5%
Calcium stearate 4%
Silicon dioxide 2%
Powder flavor 1%
Total 100%

実施例5
常法に従い、下記の玄米麺を製造した。
成分 (重量%)
脱脂米糠 10%
精製米糠油 3%
小麦粉 60%
米粉 20%
食塩 7%
合計 100%
Example 5
The following brown rice noodles were produced according to a conventional method.
Ingredient (wt%)
Degreased rice bran 10%
Refined rice bran oil 3%
60% flour
20% rice flour
7% salt
Total 100%

実施例6
常法に従い、下記のシリアルを製造した。
成分 (重量%)
米糠様組成物(フレーク) 60%
(脱脂米糠 36%)
(精製米糠油 24%)
乾燥フルーツ 30%
ミックスナッツ 10%
合計 100%
Example 6
According to a conventional method, the following cereals were produced.
Ingredient (wt%)
Rice bran-like composition (flakes) 60%
(36% defatted rice bran)
(Refined rice bran oil 24%)
30% dried fruit
10% mixed nuts
Total 100%

実施例7
常法に従い、下記の米飯用添加剤を製造した。
成分 (重量%)
米糠様組成物(顆粒) 80%
(脱脂米糠 60%)
(精製米糠油 20%)
アップルファイバー 20%
合計 100%
Example 7
In accordance with a conventional method, the following cooked rice additives were produced.
Ingredient (wt%)
Rice bran-like composition (granule) 80%
(60% defatted rice bran)
(Refined rice bran oil 20%)
Apple fiber 20%
Total 100%

実施例8
常法に従い、下記のクッキーを製造した。
成分 (重量%)
脱脂米糠 15%
精製米糠油 5%
薄力粉 20%
有塩バター 25%
砂糖 15%
鶏卵(全卵) 15%
紅茶リーフ 5%
合計 100%
Example 8
According to a conventional method, the following cookies were produced.
Ingredient (wt%)
15% defatted rice bran
Refined rice bran oil 5%
20% flour
Salted butter 25%
15% sugar
Chicken egg (whole egg) 15%
Tea leaf 5%
Total 100%

実施例9
常法に従い、下記の顆粒状食品を製造した。
成分 (重量%)
米糠様組成物(顆粒) 50%
(脱脂米糠 38%)
(精製米糠油 12%)
粉末トレハロース 20%
難消化性デキストリン 10%
粉末茶 9%
粉末香料 1%
合計 100%
Example 9
According to a conventional method, the following granular food was produced.
Ingredient (wt%)
Rice bran-like composition (granule) 50%
(38% defatted rice bran)
(Refined rice bran oil 12%)
Powdered trehalose 20%
Indigestible dextrin 10%
Powdered tea 9%
Powder flavor 1%
Total 100%

本発明の米糠様組成物における脱脂米糠及び精製米糠油の製造プロセスの一態様を示すフローチャートを示す。The flowchart which shows the one aspect | mode of the manufacturing process of the defatted rice bran and refined rice bran oil in the rice bran-like composition of this invention is shown. 試験例1にて測定されたラット初体重(左上)、ラット終体重(右上)、飼料摂取量(左下)及び総脂肪率(右下)を示す図である。It is a figure which shows the rat initial weight (upper left), rat final weight (upper right), feed intake (lower left), and total fat percentage (lower right) measured in Test Example 1. 試験例1にて測定された腸間膜脂肪量(左)、後腹壁脂肪量(右)を示す図である。It is a figure which shows the mesenteric fat mass (left) and the retroabdominal wall fat mass (right) measured in Test Example 1. 試験例1にて測定された血中のトリグリセリド量を示す図である。FIG. 3 is a diagram showing the amount of triglyceride in blood measured in Test Example 1. 試験例1にて測定された各分画におけるトリグリセリド量を示す図である。各分画は次のとおりである。CM(カイロミクロン)分画(左上)、VLDL分画(右上)、LDL分画(左下)、HDL分画(右下)。FIG. 4 is a diagram showing the amount of triglyceride in each fraction measured in Test Example 1. Each fraction is as follows. CM (chylomicron) fraction (upper left), VLDL fraction (upper right), LDL fraction (lower left), HDL fraction (lower right). 試験例3にて測定されたマウス初体重(左上)、マウス終体重(右上)及び飼料摂取量(左下)を示す図である。It is a figure which shows the mouse | mouth initial body weight (upper left), mouse | mouth final body weight (upper right), and feed intake (lower left) measured in Test Example 3. FIG. 試験例1にて測定された空腹時の血糖値を示す図である。FIG. 3 is a diagram showing fasting blood glucose levels measured in Test Example 1. 試験例1にて測定された血中の8−OHdG量(右)血中のイソプロプタン量(左)を示す図である。It is a figure which shows the amount of 8-OHdG in blood (right) and the amount of isopropane in blood (left) measured in Test Example 1.

Claims (3)

米糠を圧搾処理した脱脂米糠及び精製米糠油を、それぞれの含量が重量比で85:15〜60:40となるように含有することを特徴とする食生活改善用食品組成物。   A food composition for improving eating habits, comprising defatted rice bran obtained by pressing rice bran and refined rice bran oil so that each content is 85:15 to 60:40 by weight. メタボリックシンドロームの予防または改善のために使用するものであることを特徴とする請求項1に記載の食生活改善用食品組成物。   The food composition for improving eating habits according to claim 1, which is used for prevention or improvement of metabolic syndrome. 脱脂米糠及び精製米糠油の重量比が85:15〜60:40となるように予め含有させた米糠様組成物を製造し、該米糠様組成物を配合することを特徴とする請求項1もしくは2に記載の食生活改善用食品組成物。   2. A rice bran-like composition that is previously contained so that the weight ratio of defatted rice bran and refined rice bran oil is 85:15 to 60:40, and the rice bran-like composition is blended. 2. A food composition for improving eating habits according to 2.
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JP2020080850A (en) * 2018-11-30 2020-06-04 台湾中油股▲ふん▼有限公司CPC Corporation,Taiwan Edible composition and preparation method thereof
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