JP2009213632A - Syringe serving also as container - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a syringe serving also as a container which stores medicine solution for a long period of time without deterioration, allows the medicine solution or the blood flowing through a cylinder head to be observed clearly, and prevents the medicine solution from remaining within the syringe after injection. <P>SOLUTION: In the syringe 1 serving also as a container, the cylinder head 3 having a communication hole 12b on a luer tip 12 is fitted to the distal end side of a cylinder 2. The syringe 1 serving also as a container has a sealing plug 7c for blocking the communication hole 12b. The sealing plug 7c and a stopper 5 are made from an elastic material having corrosion resistance against the medicine solution m. In addition, at least a part of the cylinder head 3 that comes into contact with the medicine solution m is made of a synthetic resin having corrosion resistance against the medicine solution m. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a container-use syringe that can be filled and stored in advance and used immediately after being taken out of the package at the time of use.

  Since the container-use syringe is pre-filled with a chemical solution, it can be used immediately after being taken out of the package without complicated operations at a medical institution, so it is highly convenient and is used for medical operations such as doctors and nurses. It is very useful in reducing the work of the hospital, and is therefore adopted by many hospitals.

  As this container combined use syringe, it is fitted to the front end of the cylinder, the front stopper and the rear stopper which are fitted in the cylinder, the front and rear end sides in the cylinder, and seals the liquid medicine filled in the cylinder in a liquid-tight manner. , A bypass chamber into which the front stopper enters, a tube tip provided with a luer tip for attaching a syringe needle at the tip thereof, a finger grip fitted to the rear end of the cylinder, and inserted into the cylinder from the rear end portion of the cylinder And a plunger rod connected to a rear stopper is known (see, for example, Patent Document 1 and Patent Document 2).

  In use, when the rear stopper is pushed by the plunger rod and the front stopper is pushed forward together with the chemical solution, the front stopper is pushed out of the cylinder and enters the bypass chamber at the end of the cylinder. As a result, the chemical liquid sealed between the front and rear stoppers is released from the front end side and flows out from the cylinder into the bypass chamber, and this chemical liquid flows through the gap between the front stopper and the bypass chamber. It is guided to the inner surface of the luer tip along a bypass groove provided in the inner wall of the chamber and introduced into the injection needle.

  Further, when not in use, the chemical solution is filled and stored between the front and rear stoppers in the cylinder. Here, the cylinder is made of glass, and the front and rear stoppers are made of butyl rubber, and since these materials have been demonstrated to be chemically stable with respect to the chemical solution, as a container for storing the chemical solution Can be used with confidence. Therefore, the chemical solution is not deteriorated, and the container / syringe can be stored for a long time.

Further, in the conventional syringe for both containers, the cylinder and the front and rear stoppers are fitted in an airtight and liquid tight manner, so that the medicinal solution filled and sealed therein is not affected by oxygen in the air. .
In addition, the minimum and necessary amount of silicone oil is baked at a high temperature uniformly on the inner wall of the cylinder, so the front and rear stoppers slide smoothly in the cylinder even after storage for a long time. can do. When such silicone oil is baked, it can be heated at a high temperature of 250 ° C. or more at the same time, so the cylinder can be sterilized by dry heat to make pyrogen-free and endotoxin-free.
The above are the characteristics of a glass cylinder that cannot be achieved with a plastic cylinder.

On the other hand, when a glass tip is used, there are the following disadvantages.
That is, the luer tip to which the injection needle is attached must have an outer diameter of about 4 mm and an outlet having a diameter of 1.0 to 1.2 mm at the center of the shaft. It is very difficult to melt and mold the shape and dimensions according to the standards, and skilled techniques are required.
In addition, since the tube tip and luer tip formed of glass are thin with an outer diameter of 4 mm, they are easily broken even with a slight force or impact, and are difficult to manufacture. When handling at the time of injection, care must be taken in handling so that the tube tip does not break.
Furthermore, when an injection needle is attached, the glass tube tip is slippery due to the nature of the glass, and the injection needle may come off the tube tip together with the needle base during injection or the like. In particular, when silicone treatment is applied to the outer cylinder, if even a small amount of silicone oil adheres, it becomes slippery when the injection needle is attached, and the injection needle is easily removed.

Therefore, the conventional container-use syringe avoids the use of the glass tube tip having the disadvantages described above, and adopts a plastic tube tip.
When the tube tip is molded from plastic, the degree of freedom of design is high, and even if it is a complicated and difficult shape such as a luer lock, it is possible to mold it if it is possible to mold. In addition, the selection of the material makes it possible to produce a durable and impact-resistant tube tip.
In addition, since the material is somewhat elastic, even when an injection needle is attached, there is a sense of material stability at the junction with the needle base of the injection needle, and the injection needle can be easily removed during injection. There is no. At this time, if the tube tip is provided with a luer lock portion, the sense of unity can be further enhanced, and the degree of security is high.

As described above, in the conventional container-use syringe, a safe and easy-to-use container-use syringe is realized by combining the goodness of the material made of glass and plastic according to the purpose of use.
Japanese Examined Patent Publication No. 62-58745 Japanese Patent Laid-Open No. 8-148101

By the way, in general, in the injection which is a medical act of directly injecting a drug solution into a necessary site in the body by a syringe, a puncture site is determined depending on the type and effect of the drug or the purpose of use, for example, intravenous injection, It is divided into types such as arterial injection, subcutaneous injection, and intradermal injection.
Therefore, if a puncture site is mistaken, it is clear that a serious medical accident can be caused, and in order to prevent such danger, a medical solution is immediately applied after puncturing an injection needle. Without injecting, lightly pull the plunger rod toward the hand once to make negative pressure in the syringe. This ensures that if the needle tip is inside the blood vessel, blood will flow slightly into the syringe (flashback), confirming that the blade tip is inside the blood vessel. It is said.
In order to perform this procedure, when negative pressure is applied to the injection needle, the presence or absence of backflow of blood, etc. in the syringe and its color must be immediately confirmed visually. It is necessary that the presence / absence of inflow, color, etc. can be easily confirmed at the tip of the syringe.
In addition to such nurse aspiration, infusion of medicinal solution can be confirmed at the tip of the syringe even when a mixture of two or more types of medicine is injected by sucking another medicine into the syringe. Is desired.

  However, in the conventional container-use syringe as described above, the presence of the front stopper almost eliminates the space margin for visually confirming the presence and color of blood and drug solution during nurse aspiration and mixed injection. For this reason, improvements were necessary for safe injection.

  On the other hand, even if the plunger rod is completely pushed in and the chemical solution in the cylinder is introduced to the injection needle side, the bypass groove in the bypass chamber or the like allows the chemical solution to remain. There was a problem that it would occur.

  The present invention has been made in view of such a problem, and is safe and easy to use as in the case of conventional syringes for both containers and can be stored for a long time without deteriorating the drug solution. Another object of the present invention is to provide a container / syringe that can well observe a drug solution and blood flowing into a tube tip and can prevent a drug solution from remaining after injection.

In order to solve the above problems, the present invention proposes the following means.
That is, the container-use syringe according to the present invention is provided at the rear end of the cylinder made of glass and filled with a chemical solution, a stopper fitted in a liquid-tight manner on the rear end side of the cylinder, and the cylinder. And a plunger rod that is inserted into the cylinder from the rear end side of the cylinder and connected to the stopper, and a communication hole is formed on the tip side of the cylinder at a luer tip to which the injection needle is attached. In the container combined syringe in which the provided tube tip is fitted, a hermetic plug member that closes the communication hole is provided, and the hermetic plug member and the stopper are formed of an elastic body that is corrosion resistant to the chemical solution, It is characterized in that at least a contact portion of the tube tip with the chemical solution is formed of a synthetic resin having corrosion resistance to the chemical solution.

According to the container-combined syringe having such characteristics, when not in use, the chemical solution is made of a glass cylinder, a stopper and a sealing member that are elastic bodies having corrosion resistance to the chemical solution, and a synthetic resin having corrosion resistance at the tip of the tube. It will be enclosed by the place formed by.
Therefore, since all chemical solutions are chemically stable with respect to the chemical solution and are surrounded only by members that do not affect the eluate, even if the container-use syringe is stored for a long period of time, The quality of the chemical will not deteriorate.
In addition, the drug solution in the container-use syringe is held in a liquid-tight state only by the tube tip and the sealing plug member in this way. Since it can be introduced, the chemical solution can be held and introduced with a simple configuration.
Therefore, there is no need to provide a special component such as a bypass chamber or a front stopper in the conventional syringe that can be used as a container. .

In the above-mentioned syringe for both containers, the synthetic resin having corrosion resistance to the drug solution is any one of polypropylene, cyclic polyolefin, and cyclic polyolefin copolymer.
Since these synthetic resins are chemically stable and highly resistant to chemicals, it is possible to suppress deterioration of the chemicals.

  In the syringe for both containers according to the present invention, the tube tip is fitted on the luer tip member in which the luer tip is formed in the center of the flange covering the tip opening of the cylinder, and on the outer periphery of the tip of the cylinder and the outer periphery of the flange. The luer tip member is formed of a synthetic resin having a corrosion resistance against a chemical solution, and the fitting member has high transparency. It may be formed of a synthetic resin having

According to the container-use syringe having such a feature, the tube tip is composed of two members, a luer tip member and a fitting member, and the luer tip member covers the tip opening of the cylinder and seals the liquid medicine, and the fitting member The luer tip member and the cylinder are fixed and integrated.
Here, since the luer tip member is made of a synthetic resin having corrosion resistance to the chemical solution, the lure tip member does not affect the chemical solution. In addition, since the fitting member does not come into contact with the chemical solution and it is not necessary to select a material in consideration of corrosion resistance, the fitting member is formed of a material with the highest priority on transparency, so that the fitting member is attached. In addition, transparency at the outer periphery of the cylinder tip is ensured.
Therefore, it is possible to further improve the visibility of the drug solution and blood flowing into the cylinder tip and the cylinder while allowing the drug solution to be stored for a long time without deteriorating.

Further, in the container-use syringe in which the tube tip is composed of a luer tip member and a fitting member, the tube tip projects inward from the tip of the fitting member, and comes into contact with a surface facing the tip side of the flange. A locking portion for fixing the tip member in the axial direction is provided.
Thereby, since a luer tip member can be firmly integrated with a cylinder, the airtight liquid tightness of the chemical | medical solution in a cylinder can be improved.

Further, in the container-use syringe in which the tube tip is composed of a luer tip member and a fitting member, the drug solution is inserted between the tip of the cylinder and a surface facing the rear end side of the flange, and the drug solution is placed in the cylinder. It is characterized in that a rubber packing for holding the gas-tight and liquid-tight is provided.
Thereby, the airtightness of the chemical liquid in the cylinder can be further enhanced, and the leakage of the chemical liquid and the intrusion of outside air can be prevented.

The rubber packing is preferably made of butyl rubber.
Rubber packing also comes into contact with chemicals, but butyl rubber has been proven to have good stability against chemicals and high corrosion resistance, so by molding the rubber packing with butyl rubber, chemicals can be used over a long period of time. Even if it contacts with, it does not have a bad influence on a chemical | medical solution and can maintain the quality of a chemical | medical solution.

In the syringe for both a container in which the tube tip includes a luer tip member and a fitting member, the synthetic resin having the transparency is preferably polypropylene.
Since polypropylene has transparency and excellent mechanical properties, the luer tip member can be firmly fixed to the cylinder while maintaining high visibility of the chemical solution flowing into the tip. In addition, since the polypropylene has a certain degree of elasticity, it is possible to integrate the cylinder and the cylinder tip while increasing the degree of adhesion.

Further, in the above-mentioned syringe for both containers in which the tube tip is composed of a luer tip member and a fitting member, it is preferable that the synthetic resin having corrosion resistance to the chemical solution is either a cyclic polyolefin or a cyclic polyolefin copolymer.
Since these synthetic resins are chemically stable and highly resistant to chemicals, it is possible to suppress deterioration of the chemicals.

Furthermore, in the syringe for both containers according to the present invention, the sealing plug member may cover the entire outer peripheral surface of the tube tip.
As a result, the air tightness and liquid tightness at the tip of the tube tip can be further improved, and it is possible to completely prevent leakage of chemicals and intrusion of outside air during storage.

Moreover, in the said syringe used as a container, it is preferable that the said sealing plug member and the said stopper are the products made from butyl rubber.
Butyl rubber has been proven to have good chemical resistance and high corrosion resistance, so even if it comes into contact with the chemical over a long period of time, it does not adversely affect the chemical and can maintain the quality of the chemical. it can.

According to the container and syringe of the present invention, since the chemical solution can be sealed only with a member having corrosion resistance, the chemical solution can be stored for a long period of time without deteriorating.
In addition, since there is no member that obstructs the visual recognition of the inside of the tube tip, it is easy to observe the inflow of the drug solution and blood flowing into the tube tip, and nurse aspiration and co-infusion can be performed smoothly, and the remaining of the drug solution after use is prevented. It becomes possible to do.

Hereinafter, the container combined syringe according to the first embodiment of the present invention will be described in detail with reference to the drawings.
FIG. 1 is a side sectional view of the container-use syringe according to the first embodiment, and FIG. 2 is a partially enlarged view of the vicinity of the tip in FIG.

  As shown in FIG. 1, the container-use syringe 1 includes a cylinder 2, a cylinder tip 3 fitted on the outer periphery of the front end (left side in FIG. 1) of the cylinder 2, and a rear end (right side in FIG. 1). ) And a stopper 5 for sealing the chemical liquid m filled in the cylinder 2 from the rear end side, and inserted into the cylinder 2 from the rear end side. A distal end portion is connected to a stopper 5, a plunger rod 6 for reciprocating the stopper 5 in the axial direction of the cylinder 2, a rubber cap 7 attached to the distal end side of the cylinder tip 3, and an airtight liquid of the cylinder 2 in the cylinder tip 3. A rubber packing 8 is provided to maintain the tightness.

  The cylinder 2 has a cylindrical shape made of transparent glass, and a stopper 5 is inserted into the cylinder 2 so that the drug solution m is filled therein and the drug solution m is sealed from the rear end side.

  The stopper 5 has a cylindrical shape having an outer diameter that is slightly larger than the inner diameter of the cylinder 2, and is formed of an elastic body that is resistant to chemicals, such as rubber for medical drugs (butyl rubber in the present embodiment), A plunger rod 6 is connected to the rear end side.

  Further, a ring-shaped protrusion 2 c is provided on the outer peripheral portion of the rear end of the cylinder 2, and the protrusion 2 c is fitted into a ring-shaped groove 4 b formed in the cylindrical hole 4 a of the finger grip 4. The finger grip 4 is firmly attached to the cylinder 2. In addition, the finger grip 4 may be formed integrally with the cylinder 2 in addition to a structure separately attached to the cylinder 2.

  In this embodiment, the tube tip 3 is composed of two members, a luer tip member 10 and a fitting member 20, as shown in detail in FIG.

The luer tip member 10 is a member made of a synthetic resin that is chemically stable and corrosion resistant to a chemical solution m such as a cyclic polyolefin resin or a cyclic polyolefin copolymer, and seals the chemical solution m from the front end side of the cylinder 2, It has the role which introduce | transduces the said chemical | medical solution m into the injection needle which is not illustrated at the time of injection.
The luer tip member 10 includes a disc-shaped flange 11 having substantially the same diameter as the cylinder 2, a relatively small-diameter luer tip 12 coupled to the front side of the flange, and a gap radially outward of the luer tip 12. And a luer lock portion 13 coupled to the front side of the flange 11 with a gap therebetween.

In the luer tip member 10, the outer peripheral surface of the luer tip 12 is a tapered outer peripheral surface 12 a that is reduced in diameter toward the tip side, and the inside of the luer tip 12 penetrates back and forth along the axis line to the flange 11. A communication hole 12b communicating with the surface 11a facing the rear end side is formed.
Further, the luer lock portion 13 is formed with a lock screw 13a for locking a needle base of an injection needle (not shown).

The fitting member 20 is a substantially cylindrical member made of a synthetic resin having transparency, impact resistance, and elasticity such as polypropylene, and has a role of fixing and integrating the cylinder 2 and the luer tip member 12. is doing.
The inner peripheral surface of the fitting member 20 is a fitting hole 21 having an inner diameter substantially the same as the outer diameter of the cylinder 2 and the flange 11, and projects radially inward from the front end of the fitting member 20. A locking portion 22 is formed.

  When the cylinder tip 3 comprising the luer tip member 10 and the fitting member 20 as described above is attached to the cylinder 2, first, the flange 11 of the luer tip member 10 is in a state of covering the tip opening of the cylinder 2. A surface 11a facing the rear end side of the flange 11 and the front end portion 2a of the cylinder 2 are brought into contact with each other with a rubber packing 8 interposed therebetween.

  The rubber packing 8 is formed of, for example, rubber for ethical drugs (butyl rubber in the present embodiment), and has a disk shape having the same diameter as the cylinder 2. In addition, an opening 8a is formed at the center thereof, thereby ensuring a communication state between the communication hole 12b and the inside of the cylinder 2 when the luer tip member 10 is fixed to the cylinder.

In the state where the front end portion 2a of the cylinder 2 and the flange 11 are in contact with each other via the rubber packing 8 as described above, the fitting member 20 is moved from the front end side of the cylinder 2 toward the rear end side. And it is made to fit on the flange 11 of the luer tip member 10.
At this time, the luer tip member 10 is pulled toward the rear end side by the fitting member 20 by the locking portion 22 of the fitting member 20 coming into contact with the surface 11 b facing the front end side of the flange 11. As a result, the front end portion 2a of the cylinder 2, the rubber packing 8 and the flange 11 are brought into close contact with each other, and the rubber packing 8 is elastically deformed so as to be crushed, ensuring airtight and liquid tightness in the cylinder 2, and a luer tip member. 10 and the fitting member 20 are integrated by making the joint part airtight and liquidtight.
A ring-shaped protrusion 2b is provided on the outer periphery of the tip of the cylinder 2, and the protrusion 2b is fitted into a ring-shaped groove 23 formed on the front end side of the fitting hole 21 of the fitting member 20. The As a result, the fitting member 20 is firmly fitted to the outer periphery of the tip of the cylinder 2.

The rubber cap 7 is made of rubber for ethical drugs (butyl rubber in the present embodiment), is formed to be recessed from the rear end side thereof, and the outer peripheral surface of the luer lock portion 13 of the luer tip member 10 is fitted therein. One recess 7a and a second recess 7b formed so as to be further recessed from the center of the bottom of the first recess 7a and into which the tapered outer peripheral surface 12a of the luer tip member 10 is fitted. Then, the rubber cap 7 is attached to the tip of the tube tip 3 (the luer tip member 10) by closely fitting the first recess 7a and the second recess 7b with the luer lock portion 13 and the luer tip 12. It has become.
Further, a sealing plug portion 7c formed so as to protrude in a tapered shape toward the opening of the second concave portion 7b is formed at the bottom of the second concave portion 7b. When the rubber cap 7 is attached to the tube tip 3 (the luer tip member 10), the hermetic plug portion 7c has a role of sealing the drug solution m by closing the communication hole 12b in an airtight and liquid tight manner.

In the container / syringe 1 configured as described above, the drug solution m is filled in the cylinder 2, and the drug solution m is sealed at the rear end side by the stopper 5, and the tip end side is the cylinder tip 3 and the rubber cap 7. Is sealed. Therefore, in this state, only the cylinder 2, the stopper 5, the sealing plug portion 7c, the rubber packing 8, and the luer tip member 12 are in direct contact with the chemical solution m.
Here, the cylinder 2 is made of glass, and the stopper 2, the sealing plug portion 7c, and the rubber packing 8 are made of rubber for medical drugs, that is, butyl rubber, all of which are chemically with respect to the chemical solution m. Stable and corrosion resistant. Furthermore, synthetic resins such as polypropylene, cyclic polyolefin resin, and cyclic polyolefin copolymer constituting the luer tip member 12 have also been demonstrated to exhibit good corrosion resistance against the chemical solution m. Therefore, even if these members are in contact with the chemical solution m for a long period of time, the chemical solution m is not affected by the eluate or the like.
Therefore, in the syringe 1 for both containers according to the present embodiment, since the drug solution m is sealed only by a corrosion-resistant member, the container-used syringe 1 is stored for a long period of time without deteriorating the quality of the drug solution m. It becomes possible to do.

Further, as described above, the chemical solution m is sealed at the tip end side of the cylinder 2 by the luer tip member 10, the rubber packing 8, and the sealing plug portion 7c as described above, and when used, the rubber cap 7 is removed and the sealing plug portion 7c is used. Since the chemical solution m can be introduced to the tip side only by releasing the blockage of the communication hole 12b, the chemical solution m can be held and introduced with a simple configuration.
Therefore, for example, there is no need to provide a special component such as a bypass chamber or a front stopper, so that visual recognition in the tube tip 3 is not hindered.
Therefore, when nurse aspiration or mixed injection is performed, it is easy to visually confirm the presence or absence of the backflow of blood and drug solution, and the color, etc., so that the preparation for injection can be performed more smoothly. .

  Furthermore, since there is no bypass chamber or front stopper as described above, there is no room to allow the drug solution to remain after injection, and when the plunger rod 6 is pushed in and the stopper 5 is moved to the tip of the cylinder 2, Since the stopper 5 abuts on the rubber packing 8 and comes into close contact with each other while being elastically deformed, it is possible to introduce the chemical solution m into the cylinder 2 without leaving any residue in the cylinder 2.

In the present embodiment, the tube tip 3 is composed of two members, the luer tip member 10 and the fitting member 20, and the luer tip member 10 and the cylinder 2 are fixed and integrated by the fitting member 20.
As described above, since the luer tip member 10 is made of a synthetic resin having corrosion resistance to the chemical solution m, it does not affect the chemical solution. On the other hand, the fitting member 20 does not come into contact with the chemical solution m, and it is not necessary to select a material in consideration of corrosion resistance. Therefore, a material that has transparency as a top priority while having transparency (in this embodiment, polypropylene). ). Therefore, high airtightness can be ensured while ensuring transparency at the outer periphery of the tip of the cylinder 2 to which the fitting member 20 is attached.
Therefore, the tube tip 3 is composed of the luer tip member 10 and the fitting member 20, and each is formed of a synthetic resin having properties suitable for the role, so that the chemical solution m can be stored for a long time without deterioration. In addition, it is possible to provide the container-use syringe 1 with improved visibility of the drug solution and blood flowing into the cylinder tip 3 and the cylinder 2.
Further, when polypropylene is used as the material of the fitting member 20, since it has a certain degree of elasticity, the degree of adhesion with the cylinder 2 can be increased, and the cylinder tip 3 and the cylinder 2 can be more firmly connected. It can be integrated.

  Further, since the fitting member 20 is provided with the locking portion 22, the luer tip member 10 and the cylinder 2 are firmly fixed and integrated when the fitting member 20 is attached to the outer periphery of the tip of the cylinder 2. In addition, it is possible to improve the airtightness of the chemical solution m in the cylinder 2.

  Further, since the rubber packing 8 is interposed between the front end portion 2a of the cylinder 2 and the flange 11 of the luer tip member 10, the air-tight liquid tightness of the chemical liquid m in the cylinder 2 can be further improved. m leakage and intrusion of outside air can be prevented.

  Further, when the rubber cap 7 is attached, the rubber cap 7 covers the luer tip 12 and the luer lock portion 13 of the luer tip member 10, so that leakage of chemicals from the tip of the luer tip 12 and intrusion of outside air can be prevented. It becomes possible to prevent more effectively.

Next, a container combined syringe 30 according to a second embodiment of the present invention will be described with reference to FIG. In the container / use syringe 30 of the present embodiment, the tube tip 3 of the container / use syringe 1 of the first embodiment is composed of the luer tip member 10 and the fitting member 20, but these members are molded integrally. It is different in that it is the integrated tube tip 31, and is otherwise configured in the same manner as in the first embodiment.
In FIG. 3, the same components as those in FIG. 2 are denoted by the same reference numerals, and detailed description thereof is omitted.

  The integrated cylinder tip 31 has a cylindrical shape with an outer diameter made of a synthetic resin that is chemically stable and resistant to chemicals such as polypropylene, cyclic polyolefin resin, and cyclic polyolefin copolymer. Fitting portion 31b, a relatively small-diameter luer tip 31a coupled to the front side of the fitting portion 31b, and a lure tip 31a coupled to the front side of the fitting portion 31b with a space therebetween in the radial direction. And a luer lock portion 31c.

A bottomed fitting hole 31d is formed inside the fitting portion 31b. By fitting the fitting hole 31d to the outer periphery of the tip of the cylinder 2, the cylinder tip 31 is formed at the front end of the cylinder. Airtight and liquid tight. A ring-shaped groove 31i is formed on the front end side of the fitting hole 31d, and this is fitted to the ring-shaped protrusion 2b at the tip of the cylinder 2, so that the integrated tube tip 31 is at the tip of the cylinder 2. It is fitted airtight and liquid tight.
The outer surface of the luer tip 31a is a tapered outer peripheral surface 31j whose diameter decreases toward the tip side, and penetrates the lure tip 31a back and forth along the axis to communicate with the bottom 31e of 31d. A communication hole 31f is formed.
Further, the luer lock portion 31c is formed with a lock screw 31g for locking a needle base of an injection needle (not shown).

The container-use syringe 30 provided with such an integrated tube tip 31 is in a state in which the drug solution m is filled in the cylinder 2 and the rubber cap 8 is attached to the tip of the integrated tube tip 31 when not in use. . In this state, the chemical m directly contacts only the cylinder 2, the stopper 5, the sealing plug portion 7 c, and the integrated cylinder tip 31.
Therefore, as in the first embodiment, since the chemical solution m can be sealed only by a chemically stable and corrosion-resistant member with respect to the chemical solution m, the container / use syringe 30 should be stored for a long period of time. Can do.
In addition, since the integrated tube tip 31 is employed, the container-use syringe 30 can be configured with fewer components than in the first embodiment, and productivity can be improved and production cost can be reduced. It becomes.
In addition, as in the first embodiment, it is possible to ensure the visibility in the integrated cylinder tip 31 and the cylinder 2, and it is possible to prevent the drug solution m from remaining in the cylinder 2 after the injection is completed. Become.

  As described above, the first and second embodiments of the container-combined syringe according to the present invention have been described in detail. However, the present invention is not limited to these without departing from the technical idea of the present invention, and there are some design changes and the like. Is possible.

For example, as a modification of the first embodiment, the rubber cap 7 may cover the entire tube tip 3 as shown in FIG.
That is, in the rubber cap 7 in this modification, a large-diameter concave portion 7d is formed which is one step larger in diameter than the first concave portion 7a and into which the outer periphery of the fitting member 20 in the tube tip 3 is fitted.
As a result, when the rubber cap 7 is attached, the entire outer periphery of the tube tip 3 is covered, so that the leakage of the chemical solution m and the intrusion of outside air at the tip of the luer tip 12 can be prevented more reliably. It becomes possible to further improve the airtight and liquid tightness at the joint between the tip member 10 and the fitting member 20.

  Furthermore, as a modified example of the second embodiment, as shown in FIG. 5, a rubber cap 7 that covers the entire integrated cylinder tip 31 may be adopted as in the modified example of the first embodiment. Also by this, it is possible to more reliably prevent the leakage of the chemical solution m and the intrusion of outside air at the tip of the luer tip 31a.

It is a sectional side view of the container combined syringe which concerns on 1st embodiment of this invention. Of the first variation. It is a figure which shows the principal part of the syringe with a container which concerns on 2nd embodiment of this invention. It is a figure which shows the principal part of the modification of 1st embodiment. It is a figure which shows the principal part of the modification of 2nd embodiment.

Explanation of symbols

1 Syringe and syringe 2 Cylinder 3 Tube tip 4 Finger grip 5 Stopper 6 Plunger rod 7 Rubber cap (sealing member)
7c Seal plug 10 Luer tip member 11 Flange 12 Luer tip 12b Communication hole 30 Syringe for combined use with container 31 Integrated tube tip 31a Luer tip 31f Communication hole

Claims (10)

A cylindrical glass cylinder filled with a chemical solution, a stopper fitted in a liquid-tight manner on the rear end side of the cylinder, a finger grip provided at the rear end of the cylinder, and a rear end of the cylinder And a plunger rod that is inserted into the cylinder from the side and connected to the stopper, and a cylinder tip having a communication hole drilled in a luer tip to which an injection needle is attached is fitted on the tip side of the cylinder In the combination syringe,
A sealing member for closing the communication hole is provided,
The sealing member and the stopper are formed of an elastic body that is corrosion resistant to the chemical solution, and at least a contact portion with the chemical solution at the tube tip is formed of a synthetic resin that is corrosion resistant to the chemical solution. A syringe that is also used as a container.   2. The container-use syringe according to claim 1, wherein the synthetic resin having corrosion resistance to the chemical solution is any one of polypropylene, cyclic polyolefin, and cyclic polyolefin copolymer. The tube tip is
A luer tip member in which the luer tip is formed at the center of a flange covering the tip opening of the cylinder;
The outer periphery of the tip of the cylinder and the outer periphery of the flange are formed into a cylindrical shape, and includes a fitting member that fixes the luer tip member to the cylinder.
2. The container-use syringe according to claim 1, wherein the luer tip member is made of a synthetic resin having corrosion resistance against a chemical solution, and the fitting member is made of a synthetic resin having high transparency.   The engagement part which protrudes toward the inner side from the tip of the fitting member, contacts the surface facing the tip side of the flange, and fixes the luer tip member in the axial direction is provided. 3. The container combined syringe according to 3.   The rubber packing which hold | maintains the said chemical | medical solution airtightly and liquid-tightly in the said cylinder is provided between the front-end | tip of the said cylinder, and the surface which faces the rear-end side of the said flange, It is characterized by the above-mentioned. 4. The container-use syringe according to 4.   The container-use syringe according to claim 5, wherein the rubber packing is made of butyl rubber.   The syringe as a container according to any one of claims 3 to 6, wherein the synthetic resin having high transparency is polypropylene.   8. The container-use syringe according to claim 3, wherein the synthetic resin having corrosion resistance to the drug solution is any one of cyclic polyolefin and cyclic polyolefin copolymer.   The container-use syringe according to any one of claims 1 to 8, wherein the sealing plug member covers the entire outer peripheral surface of the tube tip. The container-use syringe according to any one of claims 1 to 9, wherein the sealing member and the stopper are made of butyl rubber.

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