JP2009058352A - Inspection apparatus - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a small inspection apparatus that facilitates a plurality of operations of inspection processing and makes the state of each part easy to recognize. <P>SOLUTION: This inspection apparatus having a plurality of inspection processing means comprises a controlling means for controlling the plurality of inspection processing means, and a touch panel for displaying the states of the plurality of inspection processing means and a plurality of operation buttons on one screen and detecting the input to an operation button. The controlling means controls the inspection processing means based on the input to the operation button detected by the touch panel. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to an inspection apparatus.

  In recent years, by making full use of micromachine technology and ultrafine processing technology, devices and means (for example, pumps, valves, flow paths, sensors, etc.) for performing conventional sample preparation, chemical analysis, chemical synthesis, etc. have been miniaturized. A system integrated on a chip has been developed (see, for example, Patent Document 1). This is also called μ-TAS (Micro total Analysis System), bioreactor, lab-on-chip, biochip, medical test / diagnosis field, environmental measurement field, Its application is expected in the field of agricultural production. In particular, as seen in genetic testing, when complicated processes, skilled techniques, and operation of equipment are required, the cost, required sample amount, and required time can be reduced by using μ-TAS.

  The present applicant encloses a reagent or the like in a microchannel of a microchip, injects a liquid into the microchannel by a pump, moves the reagent, and flows it to a reaction unit and then a detection unit, thereby allowing a sample such as blood to flow. Has been proposed (see, for example, Patent Document 2).

Opportunities to conduct inspections using such inspection devices are increasing, and there are many requests from inspection personnel, but installation locations in hospitals are limited, so installing multiple conventional inspection devices difficult. Therefore, a small inspection apparatus that includes a plurality of inspection processing means and can simultaneously inspect a plurality of microchips with one unit is desired.
JP 2004-28589 A JP 2006-149379 A

  However, if an operation button for operating the inspection processing means and a display means for displaying the state of each part are provided for each inspection processing means in the casing of such an inspection apparatus, the inspection apparatus becomes large. On the other hand, if the operation buttons and display contents are reduced, the operability of the inspection apparatus is impaired, and it is difficult to check the state of each part.

  The present invention has been made in view of the above-described problems, and an object of the present invention is to provide a small-sized inspection apparatus in which a plurality of inspection processes can be easily performed and the state of each part can be easily confirmed.

  The object of the present invention can be achieved by the following constitution.

1.
In an inspection apparatus having a plurality of inspection processing means,
Control means for controlling a plurality of the inspection processing means;
A plurality of operation buttons for individually operating the inspection processing means and a plurality of operation buttons for individually operating the inspection processing means, and a touch panel for detecting input to the operation buttons;
Have
The inspection device controls the inspection processing unit based on an input to the operation button detected by the touch panel.

2.
The touch panel has a selection unit for selecting the inspection processing means,
The control means includes
2. The inspection apparatus according to 1, wherein the state of the inspection processing unit and the operation buttons are displayed on the touch panel based on selection operation information of the selection unit from the touch panel.

3.
The control means includes
Screen data to be displayed on the touch panel is created in advance for each of the plurality of inspection processing means,
3. The inspection apparatus according to 2, wherein screen data of the inspection processing unit selected by the selection unit is displayed on the touch panel more than screen data of the inspection processing unit not selected by the selection unit.

  According to the present invention, the state and operation buttons of a plurality of inspection processing means are displayed on one touch panel, and the inspection processing means is controlled based on input operation information to the operation buttons. Is easy and the state of each part can be easily confirmed.

  Hereinafter, a first embodiment of the present invention will be described with reference to the drawings.

  FIG. 1 is an external view of an inspection apparatus 80 according to an embodiment of the present invention.

  The inspection device 80 is a device that automatically detects the reaction between the specimen previously injected into the microchip 1 and the reagent and displays the result on the touch panel 84.

  The housing 82 of the inspection apparatus 80 has two insertion ports 83a and 83b, and the microchips 1a and 1b are inserted into the insertion ports 83a and 83b and set inside the housing 82, respectively. In the present embodiment, the microchips 1a and 1b inserted into the two insertion openings 83a and 83b and the mechanisms for inspecting the microchips 1a and 1b inserted into the insertion openings 83a and 83b are distinguished by attaching a and b, respectively. To do. The inspection performed on the microchips 1a and 1b may be the same inspection or different inspections.

  The insertion ports 83a and 83b are sufficiently higher than the thickness of the microchips 1a and 1b so that the microchips 1a and 1b do not come into contact with the insertion port 83 when the microchips 1a and 1b are inserted. Reference numeral 85 denotes a memory card slot, 86 denotes a print output port, and 88 denotes an input / output terminal.

  The person inspecting inserts one or both of the microchips 1a and 1b in the direction of the arrow in FIG. 1 and operates the touch panel 84 to start the inspection. Inside the inspection device 80, the reaction in the microchips 1a and 1b is automatically inspected, and when the inspection is completed, the result is displayed on the touch panel 84 formed of a liquid crystal panel or the like. The test result can be output from the print output port 86 or stored in a memory card inserted in the memory card slot 85 by operating the touch panel 84. Further, data can be stored in the personal computer or the like from the external input / output terminal 88 using, for example, a LAN cable.

  The inspection person takes out the microchips 1a and 1b from the insertion openings 83a and 83b after the inspection is completed.

  Next, an example of the microchip 1 according to the embodiment of the present invention will be described with reference to FIG.

  2A and 2B are external views of the microchip 1. FIG. In FIG. 2A, an arrow indicates an insertion direction in which the microchip 1 is inserted into an inspection apparatus 80 described later, and FIG. 2A illustrates a surface that becomes the lower surface of the microchip 1 when inserted. FIG. 2B is a side view of the microchip 1.

  The window 111 in FIG. 2A is provided for optically detecting the reaction between the sample and the reagent performed by the detection unit 19 inside the microchip 1 and is made of a transparent member such as glass or resin. Yes. Reference numerals 110a, 110b, 110c, 110d, and 110e denote fluid injecting portions that communicate with internal fine flow paths, and inject fluid from each fluid injecting portion 110 to drive internal reagents and the like. Reference numeral 113 denotes a sample injection unit for injecting a sample into the microchip 1.

  In this embodiment, an example in which a liquid is injected as a fluid will be described. However, the fluid is not limited to a liquid, and may be a gas such as air.

  As shown in FIG. 2B, the microchip 1 includes a groove forming substrate 108 and a covering substrate 109 that covers the groove forming substrate 108.

  The materials used for the groove forming substrate 108 and the covering substrate 109 constituting the microchip 1 will be described.

  The microchip 1 is desired to be excellent in processability, non-water absorption, chemical resistance, weather resistance, cost and the like. In consideration of the structure, application, detection method, etc. of the microchip 1, The material of chip 1 is selected. Various known materials can be used as the material, and usually the substrate and the flow path element are formed by appropriately combining one or more materials in accordance with individual material characteristics.

  In particular, it is desirable that a chip intended for a large number of measurement specimens, particularly clinical specimens at risk of contamination and infection, be of a disposable type. Therefore, it is preferable to use a plastic resin that can be mass-produced, is lightweight, resistant to impact, and can be easily disposed of by incineration, for example, polystyrene that is excellent in transparency, mechanical properties, and moldability and is easy to be finely processed. For example, when it is necessary to heat the chip to near 100 ° C. in analysis, it is preferable to use a resin having excellent heat resistance (for example, polycarbonate). In addition, when protein adsorption becomes a problem, it is preferable to use polypropylene. Resin and glass have low thermal conductivity, and by using these materials in the locally heated region of the microchip 1, heat conduction in the surface direction is suppressed, and only the heating region is selectively heated. be able to.

  In this embodiment, since the detection unit 19 optically detects the reaction, at least the substrate at this part uses a light-transmitting material (for example, alkali glass, quartz glass, transparent plastics), and light is transmitted. It is necessary to do so. In the present embodiment, the window 111 of the detection unit is made of a light transmissive material so that light can pass through the window 111.

  In the microchip 1 according to the embodiment of the present invention, a minute groove-like flow path (fine flow path) and a functional component (flow path element) for performing inspection, sample processing, and the like correspond to applications. It is arranged in an appropriate manner. In the present embodiment, an example of a process for performing amplification and detection of a specific gene performed in the microchip 1 by using these microchannels and channel elements will be described with reference to FIG. The application of the present invention is not limited to the example of the microchip 1 described with reference to FIG. 2C, but can be applied to the microchip 1 for various uses.

  FIG. 2C is an explanatory diagram for explaining the functions of the fine flow path and flow path element inside the microchip 1.

  For example, a sample storage unit 121 that stores a sample liquid, a reagent storage unit 120 that stores reagents, a reagent storage unit 123, and the like are provided in the microchannel so that a rapid test can be performed regardless of location or time. The reagent storage units 120 and 123 store necessary reagents, a cleaning solution, a denaturing treatment solution, and the like in advance. In FIG. 2C, the reagent storage unit 120, the sample storage unit 121, and the flow path element are represented by squares, and the fine flow path therebetween is represented by a solid line and an arrow.

  The microchip 1 includes a groove forming substrate 108 in which a fine flow path is formed and a covering substrate 109 that covers the groove-shaped flow path. The fine channel is formed on the order of micrometers, for example, the width is several μm to several hundred μm, preferably 10 to 200 μm, and the depth is about 25 to 500 μm, preferably 25 to 250 μm.

  At least in the groove forming substrate 108 of the microchip 1, the fine flow path is formed. The coated substrate 109 needs to cover at least the fine flow path of the groove forming substrate in close contact, and may cover the entire surface of the groove forming substrate. Note that the microchannel 1 is provided with a part for controlling liquid feeding, such as a liquid feeding control unit (not shown), a backflow prevention unit (a check valve, an active valve, etc.), and the like. In this case, liquid feeding is performed according to a predetermined procedure.

  The sample injection unit 113 is an injection unit for injecting a sample into the microchip 1, and the fluid injection unit 110 is an injection unit for injecting a fluid into the microchip 1. Prior to performing the test using the microchip 1, the tester injects the sample from the sample injection unit 113 using a syringe or the like. As shown in FIG. 2C, the sample injected from the sample injection unit 113 is stored in the sample storage unit 121 through the communicating fine channel.

  Next, when fluid is injected from the fluid injection unit 110a, the fluid pushes the sample stored in the sample storage unit 121 through the communicating fine flow path, and sends the sample to the amplification unit 122.

  On the other hand, the fluid injected from the fluid injection part 110b pushes out the reagent stored in the reagent storage part 120a through the communicating fine channel. The reagent pushed out from the reagent storage unit 120a is sent to the amplification unit 122 by a fluid. Depending on the reaction conditions at this time, it is necessary to set the amplification unit 122 to a predetermined temperature, and as described later, the reaction is performed at a predetermined temperature by heating or absorbing heat inside the inspection device 80.

  Similarly, the fluids injected from the fluid injection units 110c, 110d, and 110e push the reagents stored in the reagent storage units 120b, 120c, and 120d through the communicating fine flow paths, respectively. The reagent pushed out from the reagent storage units 120b, 120c, and 120d is sent to the detection unit 19 by a fluid.

  After a predetermined reaction time, a solution containing the reacted specimen sent out from the amplification unit 122 by the fluid is injected into the detection unit 19. When the detection unit 19 is irradiated with light from the window 111, the reagent that has reacted with the specimen emits, for example, fluorescence. Therefore, the reaction result can be measured by measuring the amount of fluorescence. The solution after the reaction result is measured by the detection unit 19 is sent to the waste liquid storage unit 125.

  FIG. 3 is a perspective view showing an example of the internal configuration of the inspection apparatus 80 in the embodiment of the present invention, and FIG. 4 is a cross-sectional view showing an example of the internal configuration of the inspection apparatus 80 in the embodiment of the present invention.

  The inspection apparatus 80 shown in FIG. 3 has two inspection processing means including a temperature adjustment unit 152, a pump unit 92, a packing 96, a packing 97, a fluid tank 91, a driving member 303, and the like. Hereinafter, the two inspection processing units indicated by X and Y in FIG. 3 are referred to as a first inspection processing unit X and a second inspection processing unit Y, respectively.

  FIG. 3 shows a state in which the microchips 1a and 1b are in close contact with the temperature control units 152a and 152b and the packings 97a and 97b, respectively. In the microchips 1 a and 1 b shown in FIG. 3, one detection unit 19 that measures the reaction result of the reagent is provided inside the microchip 1. In this embodiment, the first inspection processing unit X and the second inspection processing unit Y that inspect the microchips 1a and 1b inserted from the insertion openings 83a and 83b have the same mechanism as shown in FIG. Will be described without distinguishing between a and b. 4 is a cross-sectional view of the mechanism shown in FIG. Hereinafter, the embodiment will be described with reference to FIGS. 3 and 4.

  The temperature adjustment unit 152 and the microchip 1 are driven by a drive member 303 including a motor 302, a feed screw 301, a tray 300, and the like, and can move in the vertical direction on the paper surface. In the initial state, the temperature adjustment unit 152 is raised from the state of FIG. 3 by the thickness of the microchip 1 by the driving member 303. Then, the microchip 1 can be inserted / removed in the direction of arrow A in FIG. 3, and the person inspecting inserts the microchip 1 from the insertion port 83 until it abuts against a regulating member (not shown) of the tray 300. When the microchip 1 is inserted to a predetermined position, the chip detection unit 95 using a photo interrupter or the like detects the microchip 1 and is turned on.

  The temperature adjustment unit 152 includes a Peltier element, a power supply device, a temperature control device, a temperature sensor, and the like, and adjusts the surface of the microchip 1 to a predetermined temperature by generating heat or absorbing heat. The temperature sensor is provided at a position corresponding to each part such as the amplifying part 122 of the microchip 1 and detects the temperature of each part.

  Next, the temperature adjustment unit 152 and the tray 300 are lowered by the driving member 303, and the microchip 1 is brought into close contact with the temperature adjustment unit 152 and the packing 97.

  In the detection unit 19 of the microchip 1, the specimen and the reagent stored in the microchip 1 react to cause, for example, coloration, light emission, fluorescence, turbidity, and the like. In this embodiment, the groove forming substrate 108 and the covering substrate 109 that constitute the detection unit 19 of the microchip 1 that measures the reaction result of the reagent are made of a light-transmitting material. Analysis can be performed by photometrically or colorimetrically measuring light transmitted through the detection unit 19 of the chip 1.

  The light detection unit 163 includes a light emitting unit 160 and a light receiving unit 161 and is arranged so as to detect light transmitted through the detection unit 19 of the microchip 1. Note that the light detection unit 163 is not limited to the method of detecting the light transmitted through the detection unit 19 of the microchip 1, and the reflected light may be detected by irradiating the detection unit 19 with light. Although the light receiving unit 161b is not shown in FIG. 3, in the present embodiment, a light emitting unit 160a, a light detecting unit 163a including the light receiving unit 161a, a light emitting unit 160b, and a light detecting unit 163b including the light receiving unit 161b are provided. And

  As shown in FIG. 4, the pump unit 92 has at least one pump 62. A packing 96 is connected to the suction side of the pump 62 so that the fluid filled in the fluid tank 91 is sucked. On the other hand, a packing 97 is connected to the discharge side of the pump 62, and the sucked fluid is injected from the fluid injection part 110 of the microchip 1 into the microchannel formed in the microchip 1 via the packing 97. . The packing 97 is sandwiched between the pump unit 92 and the microchip 1, and the fluid outlet of the pump 62, the opening of the packing 97, and the fluid injection unit 110 communicate with each other. In this manner, the fluid is injected from the fluid injection unit 110 from the pump 62 through the packing 97 that communicates with the pump 62.

  Inside the fluid tanks 91a and 91b, tank state detectors 181a and 181b (not shown in FIGS. 3 and 4) are provided, respectively. The tank state detection units 181a and 181b include a temperature sensor that detects the temperature of the fluid and a remaining amount sensor that detects the remaining amount of the fluid.

  Further, an internal temperature sensor 182 (not shown in FIGS. 3 and 4) for detecting the internal temperature is provided inside the housing 82, and an internal illuminance sensor 183 (not shown in FIGS. 3 and 4) for detecting the internal illuminance. (Not shown) is arranged.

  Next, the pump unit 92 will be described with reference to FIG.

  FIG. 5 is an explanatory diagram showing an example of the configuration of the pump unit 92 according to the embodiment of the present invention.

  The pump unit 92 includes three substrates: a silicon substrate 67, a glass substrate 68 thereon, and a glass substrate 69 thereon. The substrate 67 and the substrate 68 are joined by anodic bonding, and the substrate 68 and the substrate 69 are joined by adhesion or fusion.

  A pump 62 (piezo pump) is constituted by an internal space between the silicon substrate 67 and the glass substrate 68 bonded thereto by anodic bonding. The drive source of the pump 62 is a piezoelectric element as an example, and the liquid is fed from the left to the right in FIG. 5 by changing the volume of the internal pressurizing chamber.

  The upstream side of the pump 62 communicates with the opening 64 provided on the glass substrate through the through hole 66 a of the substrate 68 from the flow path provided on the substrate 67. The opening 64 is connected to the fluid tank 91 through the packing 96 and sucks the fluid filled in the fluid tank 91.

  A flow path 70 is patterned on the substrate 69. As an example, the size and shape of the flow path 70 is a rectangular cross section having a width of about 150 μm and a depth of about 300 μm. An opening 65 is provided on the downstream side of the flow path 70, and the liquid is fed through the flow path 70 by the pump 62. An opening is provided in the packing 97 according to the position of the opening when the packing 97 and the pump unit 92 are in close contact. In addition, since the opening of the packing 97 is provided in accordance with the position of the fluid injection unit 110 when the packing 97 is in close contact with the microchip 1, the fluid can be injected into the fluid injection unit 110 by each pump 62. .

  FIG. 6 is a circuit block diagram of the inspection apparatus 80 according to the first embodiment of the present invention.

  The control unit 99 includes a CPU 98 (central processing unit), a RAM 97 (Random Access Memory), a ROM 96 (Read Only Memory), and the like, and reads a program stored in the ROM 96 which is a nonvolatile storage unit to the RAM 97. Each part of the inspection apparatus 80 is centrally controlled according to the program.

  Hereinafter, functional blocks having the same functions as those described so far are denoted by the same reference numerals, and description thereof is omitted.

  The CPU 98 of the control unit 99 detects the state of the inspection apparatus 80 including the first inspection processing unit X and the second inspection processing unit Y and displays it on the touch panel 84. For example, the temperature and remaining amount of the fluid are displayed based on the information detected by the tank state detection units 181a and 181b, and the temperature of each part of the microchips 1a and 1b is displayed based on the information detected by the temperature adjustment units 152a and 152b. To do.

  Further, the CPU 98 of the control unit 99 displays the internal illuminance information detected by the internal illuminance sensor 183, the temperature information detected by the internal temperature sensor 183, and the opening / closing information of the housing detected by the opening / closing sensor 184 as common information. To display.

  The chip detector 95 transmits a detection signal to the CPU 98 when the microchip 1 comes into contact with the regulating member. When the position control unit 411 receives the detection signal, the position control unit 411 instructs the mechanism driving unit 32 to drive the driving member 303, and lowers or raises the microchip 1 and the temperature adjustment unit 152 in a predetermined procedure, thereby causing the fluid injection unit 110 and the pump 62 to move. Is fixed at a predetermined position where it communicates. The first embodiment includes two chip detection units 95a and 95b, two position control units 411a and 411b, and mechanism drive units 32a and 32b, which function independently of each other.

  The pump drive unit 500 is a drive unit that drives the piezoelectric element of each pump 62. The pump drive control unit 412 controls the pump drive unit 500 to inject or suck a predetermined amount of fluid based on the program. The pump drive unit 500 receives the command from the pump drive control unit 412 and drives the piezoelectric element. In this embodiment, two pump drive control units 412a and 412b and two pump drive units 500a and 500b are provided and function independently.

  The CPU 98 performs inspections in a predetermined sequence and stores the inspection results in the RAM 97. The light emitting unit 160 irradiates the detection unit 19 with light, and the light amount calculating unit 410 calculates the light amount from the electrical signal output from the light receiving unit 161 and uses it as an inspection result. In the present embodiment, a case where the light detection unit 163a and the light detection unit 163b are arranged at positions corresponding to the detection units 19a and 19b as shown in FIG. 3 will be described. Thus, the measurement may be performed by moving to a position corresponding to the detectors 19a and 19b.

  The inspection result can be stored in the memory card 501 by operating the touch panel 84 or printed by the printer 503.

  As described above, the inspection apparatus 80 stores a plurality of microchips 1 and includes inspection processing means necessary for reacting the reagents and samples in each microchip 1, so that a plurality of samples can be efficiently inspected. Can do.

  Note that the chip detection unit 95 is not essential. For example, after the microchip 1 is inserted, an inspection person may operate to start the inspection.

  7 and 8 show a first embodiment of a GUI (Graphical User Interface) 60 displayed on the touch panel 84. FIG. FIG. 7 shows an example in which detailed data of the first inspection processing unit X is displayed by operating the tab 40 a displayed on the touch panel 84. FIG. 8 is an example in which the detailed data of the second inspection processing unit Y is displayed by operating the tab 40 b displayed on the touch panel 84.

  Hereinafter, the function of each part of the GUI 60 will be described with reference to FIG. In addition, the same number is attached | subjected to the data of the same function, and a and b are attached after a number, and the data of the 1st test process part X and the data of the 2nd test process part Y are distinguished.

  40 is a tab, 41 is a test name, 42 is a specimen identification number, 43 is a test result storage file name, 44 is a test elapsed time and required test time, and a bar graph shown in FIG. 7 indicates the test elapsed time. Reference numeral 45 denotes a status display, which displays whether each part of the inspection processing unit is operating normally by changing the color. For example, the corresponding part is displayed in blue when the fluid tank 91, the pump 62, and the microchip 1 are in normal operation, and the corresponding part is displayed in orange when the inspection processing unit is unlocked.

  Reference numeral 38 denotes a start button, and 39 denotes a stop button. The inspection is started by touching the touch panel 84 in the portion of the start button 38, and the inspection is ended by touching the touch panel 84 in the portion of the stop button 39. Only one of the start button 38 and the stop button 39 is active, the start button 38 is active when the inspection is not performed, and the stop button 39 is active during the inspection. The start button 38 and the stop button 39 are operation buttons of the present invention, and the tab 40 is a selection unit of the present invention.

  Test name 41, specimen identification number 42, test result storage file name 43, test elapsed time and test required time 44, status display 45, start button 38, stop button 39 are the first test processing unit X and the second test processing unit. This is the main data and operation buttons for the inspection in Y. In FIG. 7, main data and operation buttons of the first inspection processing unit X are displayed on the left side of the GUI 60, and main data and operation buttons of the second inspection processing unit Y are displayed on the right side of the GUI 60.

  Further, detailed data of the first inspection processing unit X is displayed in the middle column of the GUI 60. 46 is a display of the detailed state of the fluid tank 91, and displays the temperature and remaining amount data of the fluid. 47 is a display of the detailed state of the pump 62, and displays the pressure of the selected pump 62. 48 is a display of the detailed state of the microchip 1, and displays the temperature of each part. 49 indicates the number of times each inspection processing unit is used.

  The above is an example of detailed data.

  Data indicating a state common to the inspection apparatus 80 and operation buttons are displayed below the GUI 60. Reference numeral 50 denotes internal temperature data of the inspection apparatus 80, and reference numeral 51 denotes internal illuminance data of the inspection apparatus 80. Reference numeral 52 denotes a power source, 53 denotes a motor, 54 denotes a network, and 55 denotes whether or not the printer is operating normally by changing colors. Reference numeral 56 denotes a maintenance button. When the maintenance button 56 is touched, the inspection apparatus 80 shifts to the maintenance mode. 57 is a date display, and 58 is a time display.

  The above is an example of common data.

  FIG. 8 shows a case where detailed data of the second inspection processing unit Y is displayed. When the tab 40b is touched, as shown in FIG. 8, main data and operation buttons of the second inspection processing unit Y are displayed in the middle column of the GUI 60, and detailed data is displayed in the right column. Touching the tab 40a returns to the display of FIG.

  As described above, the state of each part of the first inspection processing unit X and the second inspection processing unit Y, the start button 38, and the stop button 39 are displayed on the GUI 60 on the touch panel 84 of a limited size. By touching the start button 38 and the stop button 39, the inspection by the first inspection processing unit X or the second inspection processing unit Y can be easily started or ended. Further, main data of each part of the first inspection processing part X and the second inspection processing part Y are always displayed, and detailed data can be displayed as necessary, so that the state of each part can be easily confirmed.

  FIGS. 9 and 10 show a second embodiment of the GUI 60 when displaying on the touch panel 84 smaller than FIGS. 7 and 8. FIG. 9 shows an example in which main data and operation buttons of the first inspection processing unit X and the second inspection processing unit Y are displayed. FIG. 10 is an example in which main data, operation buttons, and detailed data of the first inspection processing unit X are displayed by operating the tab 40 a displayed on the touch panel 84.

  Reference numeral 40c denotes a tab for returning to the display of FIG. 9. When the tab 40c of FIG. 10 is touched, main data and operation buttons of the first inspection processing unit X and the second inspection processing unit Y are displayed as shown in FIG. . Similarly, when the tab 40b is touched, main data, operation buttons, and detailed data of the second inspection processing unit Y can be displayed.

  Thus, the main data and operation buttons of the first inspection processing unit X and the second inspection processing unit Y can be displayed even on the small touch panel 84, and detailed data can be displayed as necessary.

  In the present embodiment, the example in which the inspection processing unit is two has been described. However, even when there are three or more, the same display can be performed.

  Next, a procedure for creating data to be displayed on the GUI 60 will be described.

  FIG. 11 is a flowchart illustrating a procedure for the control unit 99 to detect the state of the inspection apparatus 80 in the embodiment of the present invention.

  The state detection routine will be described according to the flowchart. The state detection routine is executed at regular intervals by timer interruption.

  S101: This is a step of detecting the state of the common part.

  The control unit 99 acquires the internal temperature data 50 and the internal illumination data 51 from the internal illumination sensor 183 and the internal temperature sensor 182. The control unit 99 detects the states of the power supply, the motor 300, the network, and the printer 503.

  S102: This is a step of detecting the state of the first inspection processing unit X.

  The control unit 99 acquires fluid temperature and remaining amount data from the tank state detection unit 181a, and temperature data of each part of the microchip 1a from the temperature adjustment unit 152a. Further, the pressure data of each pump 62 set in the pump driving unit 500a is acquired.

  S103: This is a step of detecting the state of the second inspection processing unit Y.

  The control unit 99 acquires fluid temperature and remaining amount data from the tank state detection unit 181b and temperature data of each part of the microchip 1b from the temperature adjustment unit 152b. Moreover, the data of the pressure of each pump 62 set in the pump drive unit 500b is acquired.

  S104: This is a step of creating common part data.

  The control unit 99 determines whether the power source, the motor 300, the network, and the printer 503 are operating normally based on the result detected in step S101, and stores them in a predetermined area of the RAM 97. Internal temperature data 50, internal illuminance data 51, date, time are also stored in a predetermined area of the RAM 97.

  S105: This is a step of creating data of the first inspection processing unit X.

  The control unit 99 compares the temperature and remaining amount data of the fluid acquired in step S102, the temperature data of each part of the microchip 1a, and the pressure data of each pump 62 with a predetermined level, respectively. It is determined whether or not. The determination result is stored in the display data area of the RAM 97 together with the original data. Further, the control unit 99 reads the data of the test elapsed time and the required test time from the internal timer of the CPU 98 and the data of the test name, specimen identification number, and test result storage file name stored in the RAM 97, and displays the display data area of the RAM 97. To remember.

  S106: A step of creating data of the second inspection processing unit Y.

  The control unit 99 compares the temperature and remaining amount data of the fluid acquired in step S102, the temperature data of each part of the microchip 1b, and the pressure data of each pump 62 with predetermined levels, respectively, and is operating normally. It is determined whether or not. The determination result is stored in the display data area of the RAM 97 together with the original data. Further, the control unit 99 reads the data of the test elapsed time and the required test time from the internal timer of the CPU 98 and the data of the test name, specimen identification number, and test result storage file name stored in the RAM 97, and displays the display data area of the RAM 97. To remember.

  This is the end of the state detection routine.

  FIG. 12 is a flowchart for explaining a procedure for creating display data to be displayed on the touch panel 84 by the control unit 99 in the first embodiment of the present invention.

  The display routine will be described with reference to the flowchart of FIG. The display routine is executed at regular intervals by a timer interrupt.

  S202: A step of determining which detail display of the first inspection processing unit X and the second inspection processing unit Y is selected.

  The control unit 99 detects an input to the tab 40a or the tab 40b of the touch panel 84. If neither is touched, follow the previous results.

  When the tab 40a is selected, it is determined that the detailed display of the first inspection processing unit X is selected, and the process proceeds to step S203.

  When the tab 40b is selected, it is determined that the detailed display of the second inspection processing unit Y is selected, and the process proceeds to step S204.

  S203: This is a step of creating screen data for display.

  The control unit 99 creates and temporarily stores display screen data including main data and detailed data of the first inspection processing unit X and main data of the second inspection processing unit Y.

  S204: This is a step of creating display screen data.

  The control unit 99 creates and temporarily stores display screen data including main data of the first inspection processing unit X, main data of the second inspection processing unit Y, and detailed data.

  S205: This is a step of displaying display screen data on the touch panel 84.

  The control unit 99 transmits the display screen data to the touch panel 84 to display it.

  This is the end of the display routine.

  Next, an input processing routine for processing input using the operation buttons of the GUI 60 will be described. FIG. 13 is a flowchart for explaining a procedure by which the control unit 99 processes input by the operation button of the GUI 60 in the first embodiment of the present invention.

  The input processing routine will be described with reference to the flowchart of FIG. The input processing routine is executed at regular intervals by a timer interrupt.

  S303: This is a step of determining whether or not the maintenance button 56 has been selected.

  The control unit 99 detects an input to the maintenance button 56 of the touch panel 84.

  When the maintenance button 56 is selected, the process proceeds to step S310.

  S310: This is a step of calling a maintenance mode processing routine.

  The control unit 99 calls the maintenance mode processing routine and ends the input processing routine. Predetermined maintenance is performed by the processing routine of the maintenance mode.

  When the maintenance button 56 is not selected, the process proceeds to step S304.

  S304: This is a step of determining whether or not the start button 38a or the stop button 39a is selected.

  The control unit 99 detects an input to the start button 38a or the stop button 39a.

  When the start button 38a is selected, the process proceeds to step S306.

  S306: This is a step of calling the first inspection processing routine.

  The control unit 99 calls a first inspection processing routine for performing the inspection processing of the first inspection processing unit X, and proceeds to step S307.

  When the stop button 39a is selected, the process proceeds to step S305.

  S305: This is a step of calling the first inspection process stop routine.

  The control unit 99 calls a first inspection stop routine that performs processing for stopping the inspection of the first inspection processing unit X, and proceeds to step S307.

  When neither the start button 38 nor the stop button 39 is selected, the process proceeds to step S307.

  S307: A step of determining whether or not the start button 38b or the stop button 39b is selected.

  The control unit 99 detects an input to the start button 38b or the stop button 39b.

  When the start button 38b is selected, the process proceeds to step S309.

  S309: This is a step of calling the second inspection processing routine.

  The control unit 99 calls a second inspection processing routine for performing the inspection processing of the second inspection processing unit Y, and ends the input processing.

  When the stop button 39b is selected, the process proceeds to step S308.

  S308: This is a step of calling a second inspection process stop routine.

  The control unit 99 calls a second inspection stop routine that performs processing for stopping the inspection of the second inspection processing unit Y, and ends the input processing.

  When neither the start button 38 nor the stop button 39 is selected, the input process is terminated.

  Thus, a plurality of inspection processing operations can be easily performed by the GUI 60 displayed on the touch panel 84.

  This completes the description of the input processing routine.

  As described above, according to the present invention, it is possible to provide a small inspection apparatus in which a plurality of inspection processes can be easily performed and the state of each part can be easily confirmed.

It is an external view of the test | inspection apparatus 80 in the 1st Embodiment of this invention. It is explanatory drawing of the microchip 1 concerning embodiment of this invention. It is a perspective view which shows an example of the internal structure of the test | inspection apparatus 80 in the 1st Embodiment of this invention. It is sectional drawing which shows an example of the internal structure of the test | inspection apparatus 80 concerning embodiment of this invention. It is explanatory drawing which shows an example of the internal structure of the pump unit 92 concerning embodiment of this invention. It is a circuit block diagram of the inspection apparatus 80 in the 1st Embodiment of this invention. 3 is a first embodiment of a GUI 60 displayed on a touch panel 84. FIG. 3 is a first embodiment of a GUI 60 displayed on a touch panel 84. FIG. 3 is a second embodiment of a GUI 60 displayed on the touch panel 84. FIG. 3 is a second embodiment of a GUI 60 displayed on the touch panel 84. FIG. It is a flowchart explaining a state detection routine. It is a flowchart explaining a display routine. It is a flowchart explaining an input processing routine.

Explanation of symbols

1 microchip 19 detector 60 GUI
62 Pump 80 Inspection Device 82 Case 83 Insertion Port 84 Touch Panel 91 Fluid Tank 92 Pump Unit 96 Packing 97 Packing 110 Fluid Injection Unit 152 Temperature Control Unit 160 Light Emitting Unit 161 Light Receiving Unit 300 Tray 301 Feed Screw 302 Motor 303 Driving Member

Claims (3)

In an inspection apparatus having a plurality of inspection processing means,
Control means for controlling a plurality of the inspection processing means;
A plurality of operation buttons for individually operating the inspection processing means and a plurality of operation buttons for individually operating the inspection processing means, and a touch panel for detecting input to the operation buttons;
Have
The inspection device controls the inspection processing unit based on an input to the operation button detected by the touch panel. The touch panel has a selection unit for selecting the inspection processing means,
The control means includes
The inspection apparatus according to claim 1, wherein the state of the inspection processing unit and the operation buttons are displayed on the touch panel based on selection operation information of the selection unit from the touch panel. The control means includes
Screen data to be displayed on the touch panel is created in advance for each of the plurality of inspection processing means,
3. The inspection according to claim 2, wherein more screen data of the inspection processing unit selected by the selection unit is displayed on the touch panel than screen data of the inspection processing unit not selected by the selection unit. apparatus.

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