JP2009020040A - Device for observing living body and medical microscope using the same - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a device for observing a living body capable of improving visibility of a transparent film and semitransparent thin film in a living body. <P>SOLUTION: The device 100 for observing a living body includes an image capturing section 70 for capturing captured image data of an objective locus to be observed; an image processing section 10 for processing the captured image data captured by the image capturing section 70; an image displaying section 80 for inputting the display image data processed by the image processing section 10 and forming a display image for a user; and a color converter 50 in the image processing section 10 for converting colors of color components using color conversion factors α, β, γ defined by 1≤α/β≤3 and 1≤α/γ≤3 at R2=αG1, G2=βB1 and B2=γB1, when the RGB components of the captured image data are (R1, G1, B1) and the RGB components of the display image data are (R2, G2, B2). <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to a living body observation apparatus that is used for surgery of a minute part, particularly in neurosurgery, and more specifically, in addition to microscopic optical observation, an image of a living tissue is captured and processed, and then displayed on a display device. The present invention relates to a living body observation apparatus capable of simultaneously observing different images and a medical microscope using such an apparatus.

  Conventionally, in the field of neurosurgery, many medical microscopes for observing a surgical part in a three-dimensional manner have been used in order to reliably perform finer surgery. Furthermore, in recent years, endoscopic observation is used in combination with conventional surgery, which has been performed only under medical microscope observation, in order to perform surgery reliably, and medical microscope observation images and endoscopic imaging are medically used. It is desired to be able to observe at the same time within the field of view of the microscope. In addition to endoscopic imaging, simultaneous observation of information such as preoperative CT and MR images and intraoperative nerve monitors is also desired.

For example, Patent Document 1 (Japanese Patent Laid-Open No. 2006-301523) discloses an optical system for optical observation, an illumination optical system that illuminates the subject, and at least one image sensor that captures an observation image of the subject. A light source of the illumination optical system is composed of an LED light source that emits light of at least two different wavelength ranges including a white light LED, and each of the LEDs has a light collecting optical axis center. A medical microscope is disclosed, which is arranged so as to be substantially coaxial, and the imaging element has sensitivity corresponding to at least one wavelength region of the LED.
JP 2006-301523 A

  By the way, the conventional medical microscope as described above has a problem that the visibility of a transparent film or a semi-transparent thin film in a living body is not good. This is presumed to be caused by the fact that the scattered light inside the living body has a strong red component, and therefore the green scattered light in its complementary color becomes inconspicuous. In view of this, it was considered that there is a film scattering to some extent and the green color, which has high eye sensitivity, is strengthened regardless of the complementary color relationship. For example, when a light source or light guide with a greenish color is used and the biological film of the site to be observed is irradiated with the irradiated light, relatively good visibility can be obtained. . However, even in such observation with irradiation light, there is a limit in improving the visibility of a transparent film or a translucent thin film, which has been a problem.

  The present invention is for solving the above-described problems, and for that purpose, the invention according to claim 1 is acquired by an image capturing unit that acquires captured image data of a site to be observed, and the image capturing unit. An image processing unit that processes captured image data into display image data, an image display unit that inputs display image data processed by the image processing unit to form a display image for a user, and the image processing unit When the RGB component of the image data is (R1, G1, B1) and the RGB component of the display image data is (R2, G2, B2), the color determined by 1 ≦ α / β ≦ 3 and 1 ≦ α / γ ≦ 3 And a color conversion unit that performs color component conversion processing using R2 = αG1, G2 = βB1, and B2 = γB1 using conversion coefficients α, β, and γ.

  According to a second aspect of the present invention, there is provided an image recording unit that records captured image data of a site to be observed, an image processing unit that processes captured image data recorded in the image recording unit into display image data, An image display unit that inputs display image data processed by the image processing unit to form a display image for a user, and the image processing unit includes RGB components (R1, G1, B1) of the captured image data. When the RGB components of the data are (R2, G2, B2), R2 = αG1, G2 using color conversion coefficients α, β, γ determined by 1 ≦ α / β ≦ 3 and 1 ≦ α / γ ≦ 3. And a color conversion unit that performs a color component conversion process with βB1 and B2 = γB1.

  According to a third aspect of the present invention, in the living body observation apparatus according to the first or second aspect, the color conversion unit performs color component conversion processing with α = 1, β = 1, and γ = 1. It is characterized by.

  According to a fourth aspect of the present invention, in the living body observation apparatus according to any one of the first to third aspects, the image capturing unit acquires captured image data of a moving image at a site to be observed. To do.

  According to a fifth aspect of the present invention, in the living body observation apparatus according to any one of the first to fourth aspects, the image processing unit includes R2 = R1, G2 = G1, B2 = B1, and color components. A non-color conversion unit that does not perform the conversion process, and whether captured image data to be input to the image display unit is generated by the color conversion unit or generated by the non-color conversion unit And a display mode switching unit that performs switching.

  According to a sixth aspect of the present invention, in the living body observation apparatus according to any one of the first to fifth aspects, the image processing unit includes R2 = R1, G2 = G1, and B2 = B1 as color components. A non-color conversion unit that does not perform the conversion process, a photographic image data generated by the color conversion unit, and a photographic image data generated by the non-color conversion unit are both input to the image display unit And a selection unit.

  The invention according to claim 7 is the living body observation apparatus according to any one of claims 1 to 6, further comprising an optical display unit that displays an optical image of the site to be observed.

  An invention according to claim 8 is a medical microscope characterized by using the living body observation apparatus according to any one of claims 1 to 6.

  According to the present invention, it is possible to improve the visibility of a transparent film or a translucent thin film in a living body without changing the hardware configuration such as a light source and a light guide, and such a living body. A medical microscope using an observation apparatus can be provided.

  Hereinafter, embodiments of the present invention will be described with reference to the drawings. FIG. 1 is a block diagram illustrating the principle of a biological observation apparatus according to an embodiment of the present invention, and FIG. 2 is a block diagram of a non-conversion processing unit in the image processing unit of the biological observation apparatus according to the embodiment of the present invention. FIG. 3 is a block diagram of a conversion processing unit in the image processing unit of the biological observation apparatus according to the embodiment of the present invention.

  1 to 3, 10 is an image processing unit, 20 is a display mode switching unit, 30 is a non-color conversion unit, 31 is captured image data, 32 is captured image data R component, 33 is captured image data G component, 34 Is the captured image data B component, 41 is the display image data, 42 is the display image data R component, 43 is the display image data G component, 44 is the display image data B component, 50 is the color converter, 51 is the captured image data, 52 Is the captured image data R component, 53 is the captured image data G component, 54 is the captured image data B component, 55 is a color component conversion processing unit, 56 is a color conversion coefficient α, 57 is a color conversion coefficient β, and 58 is a color conversion coefficient. γ, 61 is display image data, 62 is display image data R component, 63 is display image data G component, 64 is display image data B component, 70 is an image capturing unit, 80 is an image display unit, 90 is an image recording unit, 100 is It shows the body observation device respectively.

  The biological observation apparatus 100 has, as a main configuration, an image photographing unit 70 capable of photographing a moving image or a still image at a site to be observed such as the inside of a living body that a user intends to observe, and the image photographing unit 70. An image processing unit 10 that performs image processing on the captured image data, an image data recording unit 80 that records the captured image data acquired by the image capturing unit 70 and the like through the image processing unit 10, and the image An image display unit 80 that forms a display image for the user by inputting data processed from captured image data to display image data by the processing unit 10 is provided.

  The image processing unit 10 receives photographed image data and performs image processing to generate display image data. In more detail, at least the display mode switching unit 20, the non-color conversion unit 30, the color conversion unit There are 50 configurations.

  As shown in FIG. 2, the non-color conversion unit 30 assumes that the RGB components of the captured image data are (R1, G1, B1) and the RGB components of the display image data are (R2, G2, B2). , G2 = G1, B2 = B1, and the color component conversion process is not performed. When such display image data that is output from the non-color conversion unit 30 is input to the image display unit 80, the image display unit 80 reproduces an image having the same color tone as that of the original observation target region.

  As shown in FIG. 2, the color conversion unit 50 assumes that the RGB components of the captured image data are (R1, G1, B1) and the RGB components of the display image data are (R2, G2, B2). Using the color conversion coefficients α (56), β (57), γ (58) determined by β ≦ 3 and 1 ≦ α / γ ≦ 3, conversion of color components with R2 = αG1, G2 = βB1, and B2 = γB1 A color component conversion processing unit 55 that performs processing is provided. When the display image data output from the color conversion unit 50 is input to the image display unit 80, an image from which the red component is removed inside the living body is reproduced, and the hardware configuration such as the light source and the light guide is changed. Therefore, the visibility of a transparent film or a semi-transparent thin film in a living body can be improved.

  Here, specific color component conversion processing in the present invention will be described. FIG. 7 is a diagram showing original photographed image data acquired by the image photographing unit. FIG. 8 is a diagram showing image data obtained by extracting only the R component of the original photographed image data acquired by the image photographing unit. FIG. 9 shows only the G component of the original photographed image data obtained by the image photographing unit. FIG. 10 is a diagram showing extracted image data, and FIG. 10 is a diagram showing image data obtained by extracting only the B component of the original photographed image data acquired by the image photographing unit. 8 to 10, the extracted R component, G component, and B component are indicated by white.

  In the original photographed image of FIG. 7, the portion surrounded by a dotted line is a transparent film. In such an original photographed image, the transparent film is difficult to recognize due to red scattered light in the living body. Such visibility problems are divided into R component, G component, and B component, and are examined in FIGS. FIG. 7 shows an image obtained by extracting only the R component of the original photographed image and replacing it with white. As shown in this image, the presence of the portion corresponding to the previous transparent film cannot be confirmed at all. In view of the above, in the living body observation apparatus 100 of the present invention, data relating to the R component in the original photographed image is discarded, and display image data is generated based on the data of the G component and the B component.

  FIG. 11 is a diagram showing an image reproduced from the original photographed image data on the image display unit after color conversion processing by the method of the present invention. In FIG. 11, the display unit 80 reproduces the display image data obtained by performing the color component conversion processing with R2 = G1, G2 = B1, and B2 = B1 (that is, α = 1, β = 1, γ = 1). Is. According to the ecological observation apparatus of the present invention, as shown in FIG. 11, the red component in the living body is removed, and the visibility of the transparent film in the living body is improved.

  Note that it is preferable to set R2 = G1, G2 = B1, and B2 = B1 because the color conversion coefficients are all 1, so that the burden on hardware such as calculation processing can be reduced. However, the color conversion coefficients α, β, and γ can be determined in the range of 1 ≦ α / β ≦ 3 and 1 ≦ α / γ ≦ 3.

  The present invention uses color conversion coefficients α, β, and γ determined by 1 ≦ α / β ≦ 3 and 1 ≦ α / γ ≦ 3, and performs color component conversion processing with R2 = αG1, G2 = βB1, and B2 = γB1. As a result, the red component in the living body is removed and the visibility of the transparent film in the living body can be improved.

  The display mode switching unit 20 switches whether display image data input to the image display unit 80 is generated by the non-color conversion unit 30 or generated by the color conversion unit 50. By providing such a configuration, in the living body observation apparatus 100 of the present invention, the image display unit 80 reproduces an image having the same color tone as that of the original observation target site, or a transparent film or translucent body in the living body. It is possible to switch whether to reproduce an image having a color tone that emphasizes a thin film or the like.

  In the present invention, in addition to the captured image data acquired by the image capturing unit 70, the captured image data recorded in the image recording unit 90 is also effective for observing a biological membrane by performing the color conversion processing as described above. It is possible to reproduce the display image.

  Next, another embodiment of the present invention will be described. FIG. 4 is a block diagram for explaining the principle of a biological observation apparatus according to another embodiment of the present invention. In FIG. 4, 100 ′ is a biological observation apparatus, 10 is an image processing unit, 70 is an image capturing unit, 80 is an image display unit, 90 is an image recording unit, 210 is an objective lens, 220 is an optical display unit, and 230 is a first display unit. An optical system 240 indicates a second optical system.

  Since the image processing unit 10, the image capturing unit 70, the image display unit 80, and the image recording unit 90 in the biological observation apparatus 100 ′ according to another embodiment shown in FIG. 4 have the same configuration as that of the previous embodiment, description will be given. Is omitted. In the present embodiment, an optical display unit 220 is provided in the vicinity of the image display unit 80, and the user refers to an optical image on the optical display unit 220 as well as electronic redevelopment by the image capturing unit 70. Is configured to be possible.

  In order to present the optical image as described above to the user, the living body observation apparatus 100 ′ according to the present embodiment is provided with an objective lens 210 that acquires an image of the observation target part. The objective lens 210 and the optical display unit A first optical system 230 is provided between 220 and 220. Further, a second optical system 240 for forming an optical image of the image of the observation target portion acquired by the objective lens 210 on a CCD or the like of the image capturing unit 70 is provided.

  According to such another embodiment of the present invention, the user appropriately refers to the three types of the original photographed image in the image display unit 80, the color conversion image that emphasizes the biological film subjected to the color conversion process, and the optical image. Thus, the state of the observation site can be grasped more accurately.

  In addition, the living body observation apparatus 100 ′ according to another embodiment of the present invention is easy to use when applied to a medical microscope. That is, the user usually performs a medical action such as surgery while referring to the optical image of the optical display unit 220, and may refer to the color conversion processing image on the image display unit 80 when the user wants to refer to the transparent film in detail. become able to. An optical system when such a biological observation apparatus 100 'is applied to a medical microscope will be described in detail later. Note that the description of the optical system later and the description of the first optical system 230 and the second optical system 240 do not necessarily coincide with each other.

  Next, another embodiment of the present invention will be described. FIG. 5 is a block diagram for explaining the principle of a biological observation apparatus according to another embodiment of the present invention. In FIG. 5, 100 ″ is a living body observation apparatus, 10 is an image processing unit, 20 is a display mode switching unit, 25 is a simultaneous display mode selection unit, 30 non-color conversion unit, 50 color conversion unit, 70 is an image photographing unit, Reference numeral 80 denotes an image display unit, and 90 denotes an image recording unit. In addition, about the structure to which the same reference number as the previous embodiment is attached | subjected, since it is the same as that of a previous thing, it abbreviate | omits description.

  In the present embodiment, when the user refers to electronic redevelopment in the image photographing unit 70, both the original photographed image and the color conversion image that emphasizes the biological film subjected to the color conversion process can be referred to at the same time. It has become. Therefore, in this embodiment, both the captured image data generated by the non-color conversion unit 30 and the captured image data generated by color conversion processing by the color conversion unit 50 are input to the image display unit 80, and the image is displayed. The display unit 80 can display two input image data. FIG. 6 is a diagram showing a display image on an image display unit in a living body observation apparatus according to another embodiment of the present invention.

  According to such a configuration of the present embodiment, the user can refer to both the original color tone image and the image in which the biological membrane is emphasized within the screen of one image display unit 80. There is an advantage that it is easy to grasp the state of the site to be observed.

  Next, an optical system of a medical microscope using the living body observation apparatus of the present invention will be described. As described in the above embodiments, in a medical microscope using the living body observation apparatus of the present invention, a user usually performs a medical action such as surgery while referring to an optical image of an optical display unit, and a transparent film. It is possible to refer to the color conversion processing image in the image display unit when it is desired to refer to the image in detail, and the observation site can be grasped more clearly.

  FIG. 12 is a diagram showing a main optical system of a medical microscope which is a living body observation apparatus according to another embodiment of the present invention, and FIG. 13 is a medical view which is a living body observation apparatus according to another embodiment of the present invention. It is a figure which shows perspectively the main optical system of the microscope for operation. 12 and 13, 501 is a light source, 502 is an illumination lens system, 503 and 504 are reflecting members (prisms), 505 is a wedge-shaped half mirror, 506 is an objective lens, 507 is an aperture stop, and 508 is a reflecting member (prism). ), 509 is an afocal zoom lens, 510 is a beam splitter, 511 is a reflecting member (prism), 512 is an imaging lens, 513 is a reflecting member (prism), 514 is an imaging point, 515 is a reflecting member (prism), 516 is a mirror, 517 and 518 are reflecting members (prisms), 519 is a relay collimator lens, 520 is a reflecting prism, 523 is a sub-observer, and 524 is an imaging system. The main optical system is configured in the body 701 of the main body of the medical microscope.

  First, the illumination system in the main optical system will be described. Light emitted from the light source 501 is imaged near the prism 504 by the illumination lens system 502. The prism 503 is installed to bend the illumination optical system in order to avoid interference with the observation optical system. As this prism, a prism having an apex angle of 90 ° or more is used to totally reflect all the luminous fluxes having a large NA. The light beam that has passed through the reflecting member 504 passes through the wedge-shaped half mirror 505 to illuminate the object surface. The light source 501 may be the light guide exit end face.

  Next, the observation system in the main optical system will be described first. The light beam from the object is reflected by the wedge-shaped half prism 505 and enters one objective lens 506 that can change the working distance. The objective lens 506 can change the working distance by moving a part of the constituting lens group. The objective lens 506 turns the light beam from the object into an afocal light beam. After exiting the objective lens 506, it passes through the left and right aperture stops of the lens barrel divided into left and right light beams and the aperture stop 507 at the conjugate position at the maximum zoom. The aperture stop 507 blocks the outside of the light beam observed on the high magnification side of the zoom system. The light beam that has passed through the aperture stop 507 is reflected upward by the prism 508 and enters the afocal zoom lens 509. The afocal zoom lens 509 enables zooming while the afocal light beam is emitted by moving at least two of the constituent lens groups. The light beam emitted from the afocal zoom group 509 enters the beam splitter 510. The beam splitter 510 includes a main observation system on the reflection side and a sub-observer 523 and an imaging system 524 on the transmission side. A sub-observer optical system is disposed after the sub-observer 523, and a photographing optical system is disposed after the photographing system 524. The photographing optical system will be described in detail later.

The main observation system is reflected downward by the reflection member 511 after being emitted from the reflection side of the beam splitter 510. After exiting the reflecting member 511, the light enters the imaging lens 512 of the imaging relay system once and forms an image at the imaging point 514 by this lens 512. After exiting the relay imaging lens 512, the light is reflected by the prism 513 to the back side of FIG. 12, reflected upward by the prism 515, and reflected by the mirror 516 to the viewer side parallel to the objective optical axis. Thereafter, the optical axes are moved to a plane including the optical axes of the objective lens 506 and the afocal zoom lens 509 by the prisms 517 and 518. The prisms 511, 513, and 515 and the mirror 516 form an II-type Porro prism to correct image inversion caused by one-time image formation.
Further, if the reflecting member 508 is reflected at an angle larger than a right angle, the head can be prevented from hitting the mirror when the mirror is horizontally used. In the case of such a configuration, the configuration can be simplified and reduced in size by adjusting the reflection angle of the mirror 516 in order to make the optical path the same as when reflected by the prism 508 at a right angle.

  After exiting the prism 518, the relay system collimator lens 519 generates an afocal beam. If the focal lengths of the imaging lens 512 and the collimator lens 519 of the one-time imaging relay system are made equal to each other and the magnification is made the afocal relay magnification to be 1, the difference in the beam diameter is reduced and the size is easily reduced. After exiting the relay collimator lens 519, the optical axis is lowered 45 ° by the twice reflecting prism 520 and is raised 45 ° by the prism 521. After the emission of the prism 521, a lens barrel 700 is attached which includes a pair of left and right imaging lenses, an upright prism that rotates the left and right images by 180 °, and a pair of eyepieces.

  The observer optical system 700 can be rotated so that the emission optical axis of the prism 521 can be rotated about the rotation axis, and can be adjusted so that the observer can observe even when the neck is tilted. In addition, if the lens barrel can be tilted in the vertical direction, the observer can adjust the observation so as to observe in a more comfortable posture.

  Next, the photographing optical system in the present embodiment will be described. FIGS. 14A to 14C are views showing a photographing optical system of a medical microscope which is a living body observation apparatus according to another embodiment of the present invention when viewed from three directions. In FIG. 14, reference numeral 601 denotes an imaging lens, 602 and 603 are reflecting members, 604 is an intermediate imaging point, 605 and 606 are reflecting members, 607 is a relay optical system, and 608 is an image sensor.

  The afocal beam transmitted through the beam splitter 510 enters the imaging lens 601 and forms an image at the intermediate imaging point 604. The imaging lens 601 has a reflecting member 602 in between, and the optical axis is bent in a right angle direction. Reflecting members 603, 605, and 606 are disposed near the image forming point, and the optical axis is bent into an M shape. Thereby, the optical path length can be increased in a small space. A relay optical system 607 that relays the imaging point 604 is disposed on the exit side of the reflecting member 606. An image of the intermediate image forming point 604 formed by the relay optical system is taken by the image sensor 608. The relay optical system 607 can be replaced, and the relay magnification can be changed in accordance with the imaging size of the image sensor 608. The image sensor 608 constitutes a part of the image imaging unit 70.

  Next, the observer optical system in the present embodiment will be described. FIG. 15 is a diagram showing an observer's optical system (binocular eyepiece tube) of a medical microscope which is a living body observation apparatus according to another embodiment of the present invention. FIG. 16 is a top view of the observer optical system (binocular eyepiece tube) in FIG. 15 and 16, reference numeral 701 denotes a mirror body, 704a and 704b are eye width adjustment housings, 705a and 705b are eyepiece housings, 707 is a fixed housing, 708 is a connection part, 709a and 709b are imaging lenses, and 710a and 710b. Is a mirror, 711a and 711b are image rotator prisms, 712a and 712b are prisms, 713a and 713b are triangular prisms, 714 is a movable housing, 715a and 715b are parallel prisms, 716a and 716b are incident reflection surfaces, and 717a and 717b are outgoing reflections Surfaces, 718a and 718b are eyepiece optical systems, 720a and 720b are second eyepiece housings, 721a and 721b are small LCD monitors, 722a and 722b are relay optical systems, 723a and 723b are prisms, 724a and 724b are prisms, and 725 , 725b denotes a second ocular optical system, respectively.

  The configuration of the observer optical system (binocular eyepiece tube) will be described with reference to FIGS. Reference numeral 707 denotes a fixed housing that is integrally attached to the mirror body portion 701 via a connection portion 708, and a pair of left and right imaging lenses 709a and 709b are disposed therein. The imaging lenses 709a and 709b are optically connected to an observation optical system (not shown) of the mirror unit 701 so that the right and left observation light beams emitted from the mirror unit 701 are incident.

  Reference numerals 710a and 710b are mirrors that respectively reflect the light beams that have passed through the imaging lenses 709a and 709b by 90 ° outward, and image rotator prisms 711a and 711b are arranged on the outgoing optical axis. Behind the image rotator prisms 711a and 711b are arranged prisms 712a and 712b that invert both observation light beams by 180 °. Further, behind this, triangular prisms 713a and 713b for reflecting the optical axes emitted from the prisms 712a and 712b in a direction parallel to the observation optical axes OL and OR by the first eyepiece optical system to be described later are optically arranged and fixed. The prisms 712a and 712b and the triangular prisms 713a and 713b are built in the movable housing 714.

  The movable housing 714 can rotate around the axis O, that is, the optical axis incident on the prisms 712a and 712b via the connection portion 715. The image rotator prisms 711a and 711b can be rotated about the axis O by a half angle with respect to the rotation of the movable housing 714 relative to the fixed housing 707 by a cam mechanism or the like (not shown).

  Reference numerals 715a and 715b are incident reflection surfaces 716a and 716b and emission reflection surfaces 717a and 717b, and are parallel prisms built in the eye width adjustment housings 704a and 704b. Light beams from the emission reflection surfaces 717a and 717b are respectively provided. They are guided to a pair of left and right first eyepiece optical systems 718a and 718b built in the eyepiece housings 705a and 705b, and constitute observation optical axes OL and OR as microscope optical observation images.

  On the other hand, 720a and 720b (only 720a in the figure) are second eyepiece housings that house the second observation optical system, and the second observation optical system is configured as follows. Although only the left side optical path in the figure, the right side has the same configuration. Reference numerals 721a and 721b are small LCD monitors that display an image of an endoscope or the like as an electronic image under the control of a controller (not shown), and are arranged and fixed between the movable housing 714 below the eye width adjustment housings 704a and 704b. ing. The small LCD monitors 721 a and 721 b constitute a part of the image display unit 80.

  Reference numerals 722a and 722b are relay optical systems disposed on the optical axes OMa and OMb emitted from the LCD monitors 721a and 721b, and the prisms 723a and 723b reflect the optical axes OMa and OMb at approximately 90 degrees. Has been placed.

  Reference numerals 724a and 724b denote prisms that deflect the optical axes reflected by the prisms 723a and 723b toward the observation optical axes OL and OR. On the outgoing optical axes O2L and O2R, a second eyepiece is provided. Optical systems 725a and 725b are optically arranged and connected, and the observation optical axes OL and O2L and OR and O2R intersect each other in the vicinity of the exit pupil position.

  As described above, according to the present invention, it is possible to improve the visibility of a transparent film or a translucent thin film in a living body without changing the hardware configuration such as a light source and a light guide, and the like. A medical microscope using a simple biological observation apparatus can be provided.

  Note that although various embodiments have been described in this specification, embodiments configured by appropriately combining the configurations of the respective embodiments are also included in the scope of the present invention.

It is a block diagram explaining the principle of the biological observation apparatus which concerns on embodiment of this invention. It is a figure which shows the block configuration of the non-conversion process part in the image process part of the biological observation apparatus which concerns on embodiment of this invention. It is a figure which shows the block configuration of the conversion process part in the image process part of the biological observation apparatus which concerns on embodiment of this invention. It is a block diagram explaining the principle of the biological observation apparatus which concerns on other embodiment of this invention. It is a block diagram explaining the principle of the biological observation apparatus which concerns on other embodiment of this invention. It is a figure which shows the display image in the image display part in the biological observation apparatus which concerns on other embodiment of this invention. It is a figure which shows the original picked-up image data acquired by the image pick-up part. It is a figure which shows the image data which extracted only the R component of the original picked-up image data acquired by the image pick-up part. It is a figure which shows the image data which extracted only the G component of the original picked-up image data acquired by the image pick-up part. It is a figure which shows the image data which extracted only B component of the original picked-up image data acquired by the image pick-up part. It is a figure which shows the image which color-converted original picked-up image data and reproduced on the image display part. It is a figure which shows the main optical systems of the medical microscope which is a biological observation apparatus which concerns on other embodiment of this invention. It is a figure which shows perspectively the main optical system of the medical microscope which is a biological observation apparatus concerning other embodiment of this invention. It is a figure which shows the imaging optical system of the medical microscope which is a biological observation apparatus which concerns on other embodiment of this invention. It is the figure which looked at the optical system for observers of a medical microscope which is a living body observation device concerning other embodiments of the present invention from the side. It is a figure which shows the optical system for observers of the medical microscope which is a biological observation apparatus which concerns on other embodiment of this invention.

Explanation of symbols

DESCRIPTION OF SYMBOLS 10 ... Image processing part, 20 ... Display mode switching part, 25 ... Simultaneous display mode selection part, 30 ... Non-color conversion part, 31 ... Shooting image data, 32 ... Shooting image Data R component, 33 ... shooting image data G component, 34 ... shooting image data B component, 41 ... display image data, 42 ... display image data R component, 43 ... display image data G Component 44... Display image data B component 50... Color conversion unit 51 .. shot image data 52 .. shot image data R component 53 .. shot image data G component 54. ..Photographed image data B component, 55... Color component conversion processing unit, 56... Color conversion coefficient .alpha., 57... Color conversion coefficient .beta. Image data, 62... Display image data R component, 63. G component, 64... Display image data B component, 70... Image capturing unit, 80... Image display unit, 90. Objective lens, 220 ... optical display unit, 230 ... first optical system, 240 ... second optical system, 501 ... light source, 502 ... illumination lens system, 503, 504 ... reflection Member (prism), 505... Wedge type, mirror, 506... Objective lens, 507... Aperture stop, 508 .. Reflecting member (prism), 509. ... Beam splitter, 511 ... Reflective member (prism), 512 ... Imaging lens, 513 ... Reflective member (prism), 514 ... Imaging point, 515 ... Reflective member (prism) ) 516 ... Mirror, 5 7, 518: Reflecting member (prism), 519: Relay system collimator lens, 520: Reflecting prism, 523: Sub-observer, 524: Imaging system, 601: Imaging lens , 602, 603... Reflective member, 604... Intermediate imaging point, 605, 606... Reflective member, 607 .. relay optical system, 608. System, 701 ... Mirror body part, 704a, 704b ... Eye width adjustment housing, 705a, 705b ... Eyepiece housing, 707 ... Fixed housing, 708 ... Connection part, 709a, 709b ... Imaging lens, 710a, 710b ... mirror, 711a, 711b ... image rotator prism, 712a, 712b ... prism, 713a, 713b ... triangular prism , 714 ... Movable ... Using, 715a, 715b ... Parallel prism, 716a, 716b ... Incident reflecting surface, 717a, 717b ... Outgoing reflecting surface, 718a, 718b ... Eyepiece optical system, 720a, 720b, second eyepiece housing, 721a, 721b, small LCD monitor, 722a, 722b, relay optical system, 723a, 723b, prism, 724a, 724b, prism, 725a, 725b ... second eyepiece optical system

Claims (8)

An image capturing unit for acquiring captured image data of an observation target part;
An image processing unit that processes captured image data acquired by the image capturing unit into display image data;
An image display unit that receives the display image data processed by the image processing unit and forms a display image for the user;
When the RGB components of the captured image data are (R1, G1, B1) and the RGB components of the display image data are (R2, G2, B2), the image processing unit 1 ≦ α / β ≦ 3 and 1 ≦ Using color conversion coefficients α, β, and γ determined by α / γ ≦ 3,
R2 = αG1, G2 = βB1, B2 = γB1
And a color conversion unit that performs color component conversion processing. An image recording unit for recording captured image data of the observation target part;
An image processing unit that processes captured image data recorded in the image recording unit into display image data;
An image display unit that receives the display image data processed by the image processing unit and forms a display image for the user;
When the RGB components of the captured image data are (R1, G1, B1) and the RGB components of the display image data are (R2, G2, B2), the image processing unit 1 ≦ α / β ≦ 3 and 1 ≦ Using color conversion coefficients α, β, and γ determined by α / γ ≦ 3,
R2 = αG1, G2 = βB1, B2 = γB1
And a color conversion unit that performs color component conversion processing. The living body observation apparatus according to claim 1, wherein the color conversion unit performs color component conversion processing according to α = 1, β = 1, and γ = 1. The living body observation apparatus according to any one of claims 1 to 3, wherein the image capturing unit acquires captured image data of a moving image at a site to be observed. In the image processing unit, R2 = R1, G2 = G1, B2 = B1, and a non-color conversion unit that does not perform color component conversion processing;
A display mode switching unit that performs switching according to whether captured image data to be input to the image display unit is generated by the color conversion unit or generated by the non-color conversion unit. The living body observation apparatus according to any one of claims 1 to 4, wherein the living body observation apparatus is characterized. The image processing unit includes a non-color conversion unit that performs R2 = R1, G2 = G1, B2 = B1, and does not perform color component conversion processing;
The simultaneous display mode selection unit that inputs both the captured image data generated by the color conversion unit and the captured image data generated by the non-color conversion unit to the image display unit. The living body observation apparatus according to any one of claims 1 to 5. The living body observation apparatus according to any one of claims 1 to 6, further comprising an optical display unit that displays an optical image of the observation target region. A medical microscope using the biological observation apparatus according to any one of claims 1 to 6.