JP2008545653A5 - - Google Patents
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- Publication number
- JP2008545653A5 JP2008545653A5 JP2008512428A JP2008512428A JP2008545653A5 JP 2008545653 A5 JP2008545653 A5 JP 2008545653A5 JP 2008512428 A JP2008512428 A JP 2008512428A JP 2008512428 A JP2008512428 A JP 2008512428A JP 2008545653 A5 JP2008545653 A5 JP 2008545653A5
- Authority
- JP
- Japan
- Prior art keywords
- mammalian cell
- adenine phosphoribosyltransferase
- inhibiting
- substrate
- ase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 210000004962 mammalian cell Anatomy 0.000 claims 5
- 102100029457 Adenine phosphoribosyltransferase Human genes 0.000 claims 4
- 108010024223 Adenine phosphoribosyltransferase Proteins 0.000 claims 4
- 230000002401 inhibitory effect Effects 0.000 claims 2
- 239000000758 substrate Substances 0.000 claims 2
- 230000004913 activation Effects 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 231100000331 toxic Toxicity 0.000 claims 1
- 230000002588 toxic effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68130505P | 2005-05-16 | 2005-05-16 | |
| PCT/US2006/018844 WO2006124847A2 (en) | 2005-05-16 | 2006-05-16 | Anti-tumoral compositions and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008545653A JP2008545653A (ja) | 2008-12-18 |
| JP2008545653A5 true JP2008545653A5 (enExample) | 2009-07-02 |
Family
ID=37432012
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008512428A Abandoned JP2008545653A (ja) | 2005-05-16 | 2006-05-16 | 抗腫瘍組成物及び方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20100151572A1 (enExample) |
| EP (1) | EP1898956A4 (enExample) |
| JP (1) | JP2008545653A (enExample) |
| CA (1) | CA2614608A1 (enExample) |
| WO (1) | WO2006124847A2 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8414910B2 (en) | 2006-11-20 | 2013-04-09 | Lutonix, Inc. | Drug releasing coatings for medical devices |
| WO2012112984A2 (en) | 2011-02-18 | 2012-08-23 | The Uab Research Foundation | Enhanced therapeutic usage of a purine nucleoside phosphorylase or nucleoside hydrolase prodrug related applications |
| CN111925997B (zh) * | 2020-06-05 | 2023-04-14 | 浙江理工大学绍兴生物医药研究院有限公司 | 表达白介素33的重组溶瘤腺病毒的构建及其应用方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6491905B1 (en) * | 1993-09-14 | 2002-12-10 | The Uab Research Foundation | Recombinant bacterial cells for delivery of PNP to tumor cells |
| AU2003297318A1 (en) * | 2002-12-20 | 2004-07-22 | Millennium Pharmaceuticals, Inc. | Methods and compositions for treating cancer using 15986, 2188, 20743, 9148, 9151, 9791, 44252, 14184, 42461, 8204, 7970, 25552, 21657, 26492, 2411, 15088, 1905, 28899, 63380, 33935, 10480, 12686, 25501, 17694, 15701, 53062, 49908, 21612, 38949, 6216, 46863, 9235, 2201, 6985, 9883, 12238, 18057, 21617, 39228, 49928, 54476. |
-
2006
- 2006-05-16 US US11/914,563 patent/US20100151572A1/en not_active Abandoned
- 2006-05-16 JP JP2008512428A patent/JP2008545653A/ja not_active Abandoned
- 2006-05-16 EP EP06770406A patent/EP1898956A4/en not_active Withdrawn
- 2006-05-16 CA CA002614608A patent/CA2614608A1/en not_active Abandoned
- 2006-05-16 WO PCT/US2006/018844 patent/WO2006124847A2/en not_active Ceased
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