JP2008541745A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2008541745A5 JP2008541745A5 JP2008514036A JP2008514036A JP2008541745A5 JP 2008541745 A5 JP2008541745 A5 JP 2008541745A5 JP 2008514036 A JP2008514036 A JP 2008514036A JP 2008514036 A JP2008514036 A JP 2008514036A JP 2008541745 A5 JP2008541745 A5 JP 2008541745A5
- Authority
- JP
- Japan
- Prior art keywords
- formulation
- dson
- transfection
- cells
- transfection agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US68601005P | 2005-06-01 | 2005-06-01 | |
| US60/686,010 | 2005-06-01 | ||
| PCT/EP2006/006340 WO2006128739A1 (en) | 2005-06-01 | 2006-06-01 | Oligonucleotides for rna interference and biological applications thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2008541745A JP2008541745A (ja) | 2008-11-27 |
| JP2008541745A5 true JP2008541745A5 (https=) | 2009-07-09 |
| JP5371424B2 JP5371424B2 (ja) | 2013-12-18 |
Family
ID=37075816
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008514036A Expired - Fee Related JP5371424B2 (ja) | 2005-06-01 | 2006-06-01 | Ｒｎａ干渉のためのオリゴヌクレオチドおよびその生物学的適用 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8802640B2 (https=) |
| EP (1) | EP1888749B1 (https=) |
| JP (1) | JP5371424B2 (https=) |
| CN (1) | CN101213300B (https=) |
| DK (1) | DK1888749T3 (https=) |
| WO (1) | WO2006128739A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1888749T3 (en) | 2005-06-01 | 2015-01-05 | Polyplus Transfection | Oligonucleotides for RNA interference and their biological applications |
| EP3342415B1 (en) | 2006-08-08 | 2022-01-26 | Rheinische Friedrich-Wilhelms-Universität Bonn | Structure and use of 5' phosphate oligonucleotides |
| CN101686939B (zh) | 2007-04-17 | 2013-03-27 | 巴克斯特国际公司 | 用于肺部投送的核酸微粒 |
| EP2297323A1 (en) | 2008-05-21 | 2011-03-23 | Hartmann, Gunther | 5' triphosphate oligonucleotide with blunt end and uses thereof |
| EP2508530A1 (en) | 2011-03-28 | 2012-10-10 | Rheinische Friedrich-Wilhelms-Universität Bonn | Purification of triphosphorylated oligonucleotides using capture tags |
| EP2712870A1 (en) | 2012-09-27 | 2014-04-02 | Rheinische Friedrich-Wilhelms-Universität Bonn | Novel RIG-I ligands and methods for producing them |
| US20170137808A1 (en) * | 2014-03-20 | 2017-05-18 | Oommen Varghese | Improved small interfering ribonucleic acid molecules |
| WO2016110691A1 (en) * | 2015-01-06 | 2016-07-14 | The University Court Of The University Of Aberdeen | Enhanced rnai mediated gene regulation |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6506559B1 (en) * | 1997-12-23 | 2003-01-14 | Carnegie Institute Of Washington | Genetic inhibition by double-stranded RNA |
| WO2002081628A2 (en) * | 2001-04-05 | 2002-10-17 | Ribozyme Pharmaceuticals, Incorporated | Modulation of gene expression associated with inflammation proliferation and neurite outgrowth, using nucleic acid based technologies |
| US20030212022A1 (en) * | 2001-03-23 | 2003-11-13 | Jean-Marie Vogel | Compositions and methods for gene therapy |
| PT1309726E (pt) | 2000-03-30 | 2010-03-08 | Whitehead Biomedical Inst | Mediadores de interferência por rna específicos de sequência de rna |
| US20040259247A1 (en) | 2000-12-01 | 2004-12-23 | Thomas Tuschl | Rna interference mediating small rna molecules |
| DK1888749T3 (en) | 2005-06-01 | 2015-01-05 | Polyplus Transfection | Oligonucleotides for RNA interference and their biological applications |
-
2006
- 2006-06-01 DK DK06754634.1T patent/DK1888749T3/en active
- 2006-06-01 US US11/921,089 patent/US8802640B2/en active Active
- 2006-06-01 WO PCT/EP2006/006340 patent/WO2006128739A1/en not_active Ceased
- 2006-06-01 JP JP2008514036A patent/JP5371424B2/ja not_active Expired - Fee Related
- 2006-06-01 EP EP06754634.1A patent/EP1888749B1/en active Active
- 2006-06-01 CN CN2006800237824A patent/CN101213300B/zh active Active
-
2014
- 2014-07-01 US US14/321,086 patent/US9243248B2/en active Active
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP2146632A4 (en) | COMPOSITIONS AND METHODS FOR CELLULAR IMAGE PRESENTATION AND THERAPY | |
| EP2379079A4 (en) | PHARMACEUTICAL FORMULATIONS WITH VORICONAZOLE AND METHOD OF MANUFACTURING THEREOF | |
| EP1865967A4 (en) | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS AND OTHER DISEASES | |
| WO2007095316A3 (en) | Compositions and methods for oligonucleotide formulations | |
| BRPI0806531A2 (pt) | Composto, composição farmacêutica, agente terapêutico, e, uso do composto. | |
| BRPI0913379A2 (pt) | formulações farmacêuticas sólidas compreendendo bibw 2992 | |
| EP2251038A4 (en) | SOLID DISPERSION, PHARMACEUTICAL COMPOSITIONS THEREFOR AND METHOD FOR THE PRODUCTION THEREOF | |
| EP1976489A4 (en) | MULTIPLE UNITS EXISTING ORAL FORMULATION WITH DELAYED RELEASE AND MANUFACTURING METHOD THEREFOR | |
| BRPI0719594A2 (pt) | Partícula de liberação contendo agente de benefício | |
| EP2015740A4 (en) | NEW LOW-DOSED PHARMACEUTICAL COMPOSITIONS WITH NIMESULID, PREPARATION AND USE | |
| EP2364084A4 (en) | PHARMACEUTICAL COMPOSITIONS WITH LIPONIC ACID IN LOW DOSAGE AND METHOD | |
| EP2178549A4 (en) | ANTIMICROBIAL PEPTIDE, COMPOSITIONS AND USE METHOD | |
| WO2010017215A3 (en) | Biodegradable microspheres and methods of use thereof | |
| IL208982B (en) | A preparation containing baclofen or a salt, derivative or delayed release formulation thereof for use in the treatment of Alzheimer's disease | |
| BRPI0807285A2 (pt) | "composição, método para preparar composição farmacêutica, forma unitária de dosagem, método para admnistrar um agente biologicamente ativo a um animal necessitando o agente, método para aumentar a biodisponibilidade de um agente biologicamente ativo, método para preparar uma composição e composto" | |
| EP2124556A4 (en) | PHARMACEUTICAL COMPOSITIONS | |
| EP2061800A4 (en) | COMPOSITIONS WITH HMW-MAA AND FRAGMENTS AND METHOD FOR THEIR USE | |
| EP3272337A3 (en) | Tablets | |
| WO2007122581A3 (en) | Compositions and kits of phenylephrine | |
| EP2320740A4 (en) | PHARMACEUTICAL COMPOSITIONS AND METHOD FOR PRODUCING CONCENTRATIONS THEREOF OF LITTLE CONTAMINATION | |
| DE602008000786D1 (de) | 1,2,4,5-Tetrahydro-3H-Benzazepinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen | |
| EP1987825A4 (en) | PHARMACEUTICAL COMPOSITION WITH OSELTAMIVIRPHOSPHATE | |
| WO2008063768A3 (en) | Compositions and methods for treating metabolic diseases | |
| WO2009117401A3 (en) | Compositions for site-specific delivery of imatinib and methods of use | |
| EP2473051A4 (en) | NEW COMPOSITIONS AND METHODS OF PREPARING 5-AMINO OR SUBSTITUTED AMINO-1,2,3-TRIAZOLES AND TRIAZOOL OROTATE FORMULATIONS |