JP2008541745A5 - - Google Patents

Download PDF

Info

Publication number
JP2008541745A5
JP2008541745A5 JP2008514036A JP2008514036A JP2008541745A5 JP 2008541745 A5 JP2008541745 A5 JP 2008541745A5 JP 2008514036 A JP2008514036 A JP 2008514036A JP 2008514036 A JP2008514036 A JP 2008514036A JP 2008541745 A5 JP2008541745 A5 JP 2008541745A5
Authority
JP
Japan
Prior art keywords
formulation
dson
transfection
cells
transfection agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2008514036A
Other languages
English (en)
Japanese (ja)
Other versions
JP2008541745A (ja
JP5371424B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2006/006340 external-priority patent/WO2006128739A1/en
Publication of JP2008541745A publication Critical patent/JP2008541745A/ja
Publication of JP2008541745A5 publication Critical patent/JP2008541745A5/ja
Application granted granted Critical
Publication of JP5371424B2 publication Critical patent/JP5371424B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2008514036A 2005-06-01 2006-06-01 Ｒｎａ干渉のためのオリゴヌクレオチドおよびその生物学的適用 Expired - Fee Related JP5371424B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68601005P 2005-06-01 2005-06-01
US60/686,010 2005-06-01
PCT/EP2006/006340 WO2006128739A1 (en) 2005-06-01 2006-06-01 Oligonucleotides for rna interference and biological applications thereof

Publications (3)

Publication Number Publication Date
JP2008541745A JP2008541745A (ja) 2008-11-27
JP2008541745A5 true JP2008541745A5 (https=) 2009-07-09
JP5371424B2 JP5371424B2 (ja) 2013-12-18

Family

ID=37075816

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2008514036A Expired - Fee Related JP5371424B2 (ja) 2005-06-01 2006-06-01 Ｒｎａ干渉のためのオリゴヌクレオチドおよびその生物学的適用

Country Status (6)

Country Link
US (2) US8802640B2 (https=)
EP (1) EP1888749B1 (https=)
JP (1) JP5371424B2 (https=)
CN (1) CN101213300B (https=)
DK (1) DK1888749T3 (https=)
WO (1) WO2006128739A1 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5371424B2 (ja) 2005-06-01 2013-12-18 ポリプラス トランスフェクション エスアー Ｒｎａ干渉のためのオリゴヌクレオチドおよびその生物学的適用
ES2911034T3 (es) * 2006-08-08 2022-05-17 Univ Bonn Rheinische Friedrich Wilhelms Estructura y uso de oligonucleótidos 5' fosfato
CN101686939B (zh) 2007-04-17 2013-03-27 巴克斯特国际公司 用于肺部投送的核酸微粒
WO2009141146A1 (en) 2008-05-21 2009-11-26 Gunther Hartmann 5' triphosphate oligonucleotide with blunt end and uses thereof
EP2508530A1 (en) 2011-03-28 2012-10-10 Rheinische Friedrich-Wilhelms-Universität Bonn Purification of triphosphorylated oligonucleotides using capture tags
EP2712870A1 (en) 2012-09-27 2014-04-02 Rheinische Friedrich-Wilhelms-Universität Bonn Novel RIG-I ligands and methods for producing them
EP3119887B1 (en) * 2014-03-20 2019-02-20 Oommen Varghese Improved small interfering ribonucleic acid molecules
WO2016110691A1 (en) * 2015-01-06 2016-07-14 The University Court Of The University Of Aberdeen Enhanced rnai mediated gene regulation

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6506559B1 (en) * 1997-12-23 2003-01-14 Carnegie Institute Of Washington Genetic inhibition by double-stranded RNA
US20030212022A1 (en) * 2001-03-23 2003-11-13 Jean-Marie Vogel Compositions and methods for gene therapy
ES2336887T5 (es) 2000-03-30 2019-03-06 Whitehead Inst Biomedical Res Mediadores de interferencia por ARN específicos de secuencias de ARN
CA2429814C (en) * 2000-12-01 2014-02-18 Thomas Tuschl Rna interference mediating small rna molecules
EP1386004A4 (en) * 2001-04-05 2005-02-16 Ribozyme Pharm Inc MODULATION OF GENE EXPRESSION ASSOCIATED WITH INFLAMMATORY PROLIFERATION AND GROWTH OF NEURITIES BY METHODS INVOLVING NUCLEIC ACID
JP5371424B2 (ja) 2005-06-01 2013-12-18 ポリプラス トランスフェクション エスアー Ｒｎａ干渉のためのオリゴヌクレオチドおよびその生物学的適用

Similar Documents

Publication Publication Date Title
EP2146632A4 (en) COMPOSITIONS AND METHODS FOR CELLULAR IMAGE PRESENTATION AND THERAPY
EP2379079A4 (en) PHARMACEUTICAL FORMULATIONS WITH VORICONAZOLE AND METHOD OF MANUFACTURING THEREOF
EP1865967A4 (en) COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS AND OTHER DISEASES
EP2279008A4 (en) PHARMACEUTICAL COMPOSITIONS OF PACLITAXEL, PACLITAXEL ANALOGUE OR PACLITAXEL CONJUGATES AND RELEVANT MANUFACTURING AND USE METHOD
WO2007095316A3 (en) Compositions and methods for oligonucleotide formulations
BRPI0806531A2 (pt) Composto, composição farmacêutica, agente terapêutico, e, uso do composto.
BRPI0913379A2 (pt) formulações farmacêuticas sólidas compreendendo bibw 2992
EP2251038A4 (en) SOLID DISPERSION, PHARMACEUTICAL COMPOSITIONS THEREFOR AND METHOD FOR THE PRODUCTION THEREOF
EP1976489A4 (en) MULTIPLE UNITS EXISTING ORAL FORMULATION WITH DELAYED RELEASE AND MANUFACTURING METHOD THEREFOR
BRPI0719594A2 (pt) Partícula de liberação contendo agente de benefício
EP2015740A4 (en) NEW LOW-DOSED PHARMACEUTICAL COMPOSITIONS WITH NIMESULID, PREPARATION AND USE
EP2364084A4 (en) PHARMACEUTICAL COMPOSITIONS WITH LIPONIC ACID IN LOW DOSAGE AND METHOD
EP2178549A4 (en) ANTIMICROBIAL PEPTIDE, COMPOSITIONS AND USE METHOD
WO2010017215A3 (en) Biodegradable microspheres and methods of use thereof
EP2327750A4 (en) LIABILITY AND LIABILITY THEREWITH
IL208982B (en) A preparation containing baclofen or a salt, derivative or delayed release formulation thereof for use in the treatment of Alzheimer's disease
BRPI0807285A2 (pt) "composição, método para preparar composição farmacêutica, forma unitária de dosagem, método para admnistrar um agente biologicamente ativo a um animal necessitando o agente, método para aumentar a biodisponibilidade de um agente biologicamente ativo, método para preparar uma composição e composto"
EP2124556A4 (en) PHARMACEUTICAL COMPOSITIONS
EP2061800A4 (en) COMPOSITIONS WITH HMW-MAA AND FRAGMENTS AND METHOD FOR THEIR USE
ZA200810166B (en) Phenylephrine pharmaceutical formulations and compositions for colonic absorption
EP3272337A3 (en) Tablets
WO2007122581A3 (en) Compositions and kits of phenylephrine
EP2320740A4 (en) PHARMACEUTICAL COMPOSITIONS AND METHOD FOR PRODUCING CONCENTRATIONS THEREOF OF LITTLE CONTAMINATION
EP2367808A4 (en) PROGESTATIVE 3- (6,6-ETHYLENE-17b-HYDROXY-3-OXO-17a-PREGNA-4-EN-17a-YL) PROPIONIC ACID g-LACTONE
EP1987825A4 (en) PHARMACEUTICAL COMPOSITION WITH OSELTAMIVIRPHOSPHATE