JP2008531730A - I型真性糖尿病及び他の症状を治療するための方法及び薬学的組成物 - Google Patents
I型真性糖尿病及び他の症状を治療するための方法及び薬学的組成物 Download PDFInfo
- Publication number
- JP2008531730A JP2008531730A JP2007558291A JP2007558291A JP2008531730A JP 2008531730 A JP2008531730 A JP 2008531730A JP 2007558291 A JP2007558291 A JP 2007558291A JP 2007558291 A JP2007558291 A JP 2007558291A JP 2008531730 A JP2008531730 A JP 2008531730A
- Authority
- JP
- Japan
- Prior art keywords
- cells
- islet
- diabetes
- insulin
- pancreatic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2278—Vasoactive intestinal peptide [VIP]; Related peptides (e.g. Exendin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
- C07K16/2809—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Marine Sciences & Fisheries (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Emergency Medicine (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US65896505P | 2005-03-04 | 2005-03-04 | |
| US68208705P | 2005-05-18 | 2005-05-18 | |
| US68481905P | 2005-05-25 | 2005-05-25 | |
| PCT/US2006/007750 WO2006096565A2 (en) | 2005-03-04 | 2006-03-03 | Methods and pharmaceutical compositions for treating type 1 diabetes mellitus and other conditions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008531730A true JP2008531730A (ja) | 2008-08-14 |
| JP2008531730A5 JP2008531730A5 (https=) | 2009-04-23 |
Family
ID=36570401
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007558291A Pending JP2008531730A (ja) | 2005-03-04 | 2006-03-03 | I型真性糖尿病及び他の症状を治療するための方法及び薬学的組成物 |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US8211430B2 (https=) |
| EP (1) | EP1858545A2 (https=) |
| JP (1) | JP2008531730A (https=) |
| WO (1) | WO2006096565A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018528970A (ja) * | 2015-09-16 | 2018-10-04 | サントル、ナショナール、ド、ラ、ルシェルシュ、シアンティフィク、(セーエヌエルエス) | 悪性腫瘍を治療および/または腫瘍再発を予防するためのゲル化組成物 |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040037826A1 (en) * | 2002-06-14 | 2004-02-26 | Michelsen Birgitte Koch | Combined use of a modulator of CD3 and a GLP-1 compound |
| US20090142338A1 (en) * | 2005-03-04 | 2009-06-04 | Curedm, Inc. | Methods and Compositions for Treating Type 1 and Type 2 Diabetes Mellitus and Related Conditions |
| EP1883417A2 (en) | 2005-05-25 | 2008-02-06 | Curedm Inc. | Peptides, derivatives and analogs thereof, and methods of using same |
| US20090318392A1 (en) * | 2006-09-14 | 2009-12-24 | Zora Biosciences Oy | Biofluid metabolite profiling as a tool for early prediction of autoimmunity and type 1 diabetes risk |
| WO2008064306A2 (en) * | 2006-11-22 | 2008-05-29 | Curedm, Inc. | Methods and compositions relating to islet cell neogenesis |
| TW200826088A (en) * | 2006-12-08 | 2008-06-16 | Lite On It Corp | Optical disk drive with defocus-prohibited device |
| EA201000399A1 (ru) * | 2007-08-30 | 2011-02-28 | Кьюрдм, Инк. | Композиции и способы использования проостровковых пептидов и их аналогов |
| CA2699073A1 (en) * | 2007-09-11 | 2009-04-02 | Mondobiotech Laboratories Ag | Use of a peptide as a therapeutic agent |
| US20110082080A1 (en) * | 2007-10-12 | 2011-04-07 | Curedm Group Holdings, Llc | Compositions and methods of using the human proislet peptide receptor |
| EP2242513A2 (en) | 2008-01-18 | 2010-10-27 | Hadasit Medical Research Services & Development Ltd. | Combination therapy of beta-glycolipids and antibodies for the treatment of immune-related disorders |
| WO2010025555A1 (en) | 2008-09-08 | 2010-03-11 | Ottawa Hospital Research Institute | Periostin-induced pancreatic regeneration |
| WO2010052144A2 (en) * | 2008-11-05 | 2010-05-14 | F. Hoffmann-La Roche Ag | Neuropeptide-2-receptor (y-2r) agonists and uses thereof |
| WO2011050104A2 (en) * | 2009-10-20 | 2011-04-28 | Tolerx, Inc. | Methods of using anti-cd3 antibodies to prevent weight gain |
| CN104203263A (zh) * | 2012-03-01 | 2014-12-10 | 耶达研究与发展有限公司 | 利用HSP60衍生肽再生胰岛β细胞 |
| CA2864655A1 (en) * | 2012-03-01 | 2013-09-06 | Yeda Research And Development Co. Ltd. | Hsp60 derived peptides and peptide analogs for suppression and treatment of non-autoimmune diabetes |
| US20170081375A1 (en) * | 2012-10-26 | 2017-03-23 | Claresa Levetan | Generation of brain and spinal cord neurons, cardiac myocytes, renal nephrons and hepatocytes using reg peptides, peptidomimetics, small molecules and stimulatory antibodies to reg receptor |
| FR3004354A1 (fr) * | 2013-04-10 | 2014-10-17 | Alfact Innovation | Composition comprenant la proteine hip/pap ou l'un de ses derives pour le traitement de la resistance a l'insuline |
| US20160039876A1 (en) * | 2014-03-28 | 2016-02-11 | Claresa Levetan | Insulin independence among patients with diabetes utilizing an optimized hamster reg3 gamma peptide |
| US10378055B2 (en) * | 2015-04-08 | 2019-08-13 | City Of Hope | Methods and compositions for measuring beta cell death |
| WO2020210697A1 (en) * | 2019-04-12 | 2020-10-15 | Sdg, Inc. | Lipid-based nanoparticles and use of same in optimized insulin dosing regimens |
| IL322315A (en) | 2019-05-14 | 2025-09-01 | Provention Bio Inc | Methods and preparations for preventing type 1 diabetes |
| US12153056B2 (en) | 2019-07-15 | 2024-11-26 | Washington University | Compositions for and methods of diagnosing, prognosing, and treating diabetes |
| AU2021287998B2 (en) | 2020-06-11 | 2026-03-12 | Benaroya Research Institute At Virginia Mason | Methods and compositions for preventing type 1 diabetes |
| US12565529B2 (en) | 2021-05-24 | 2026-03-03 | Provention Bio, Inc. | Methods for treating type 1 diabetes |
| CN115850486B (zh) * | 2022-11-16 | 2023-05-30 | 艾可泰科(浙江)控股有限公司 | 胰岛干细胞在治疗糖尿病中的用途 |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003094958A1 (en) * | 2002-05-09 | 2003-11-20 | Medtronic Minimed, Inc. | Immunoprotective methods for beta cell neogenesis |
| WO2003105897A1 (en) * | 2002-06-14 | 2003-12-24 | Novo Nordisk A/S | Combined use of a modulator of cd3 and a glp-1 compound |
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| US20090142338A1 (en) * | 2005-03-04 | 2009-06-04 | Curedm, Inc. | Methods and Compositions for Treating Type 1 and Type 2 Diabetes Mellitus and Related Conditions |
| EP1883417A2 (en) * | 2005-05-25 | 2008-02-06 | Curedm Inc. | Peptides, derivatives and analogs thereof, and methods of using same |
| WO2008064306A2 (en) * | 2006-11-22 | 2008-05-29 | Curedm, Inc. | Methods and compositions relating to islet cell neogenesis |
| EA201000399A1 (ru) * | 2007-08-30 | 2011-02-28 | Кьюрдм, Инк. | Композиции и способы использования проостровковых пептидов и их аналогов |
-
2006
- 2006-03-03 US US11/367,682 patent/US8211430B2/en not_active Expired - Fee Related
- 2006-03-03 EP EP06721151A patent/EP1858545A2/en not_active Withdrawn
- 2006-03-03 WO PCT/US2006/007750 patent/WO2006096565A2/en not_active Ceased
- 2006-03-03 JP JP2007558291A patent/JP2008531730A/ja active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003094958A1 (en) * | 2002-05-09 | 2003-11-20 | Medtronic Minimed, Inc. | Immunoprotective methods for beta cell neogenesis |
| WO2003105897A1 (en) * | 2002-06-14 | 2003-12-24 | Novo Nordisk A/S | Combined use of a modulator of cd3 and a glp-1 compound |
Non-Patent Citations (4)
| Title |
|---|
| JPN6011043985; Diabetes Vol.53, No.7, 2004, p.1700-1705 * |
| JPN6011043988; 内分泌・糖尿病科 第20巻,第1号, 20050128, p.69-74 * |
| JPN6011043990; Annals of Surgery Vol.240, No.5, 2004, p.875-884 * |
| JPN6011043992; Lancet Vol.358, No.9295, 2001, p.1749-1753 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018528970A (ja) * | 2015-09-16 | 2018-10-04 | サントル、ナショナール、ド、ラ、ルシェルシュ、シアンティフィク、(セーエヌエルエス) | 悪性腫瘍を治療および/または腫瘍再発を予防するためのゲル化組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1858545A2 (en) | 2007-11-28 |
| WO2006096565A3 (en) | 2006-12-14 |
| US20060198839A1 (en) | 2006-09-07 |
| WO2006096565A2 (en) | 2006-09-14 |
| US8211430B2 (en) | 2012-07-03 |
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