JP2008526873A5 - - Google Patents
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- Publication number
- JP2008526873A5 JP2008526873A5 JP2007550477A JP2007550477A JP2008526873A5 JP 2008526873 A5 JP2008526873 A5 JP 2008526873A5 JP 2007550477 A JP2007550477 A JP 2007550477A JP 2007550477 A JP2007550477 A JP 2007550477A JP 2008526873 A5 JP2008526873 A5 JP 2008526873A5
- Authority
- JP
- Japan
- Prior art keywords
- organic acid
- palmar
- solution
- acid
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 231100000433 cytotoxic Toxicity 0.000 claims 6
- 230000001472 cytotoxic effect Effects 0.000 claims 6
- 229910052751 metal Inorganic materials 0.000 claims 6
- 239000002184 metal Substances 0.000 claims 6
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 claims 5
- 239000003937 drug carrier Substances 0.000 claims 3
- 210000004881 tumor cell Anatomy 0.000 claims 3
- 230000006907 apoptotic process Effects 0.000 claims 2
- 150000004696 coordination complex Chemical class 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 150000007522 mineralic acids Chemical class 0.000 claims 2
- 150000007524 organic acids Chemical class 0.000 claims 2
- 239000004094 surface-active agent Substances 0.000 claims 2
- 239000003021 water soluble solvent Substances 0.000 claims 2
- VEEGZPWAAPPXRB-BJMVGYQFSA-N (3e)-3-(1h-imidazol-5-ylmethylidene)-1h-indol-2-one Chemical compound O=C1NC2=CC=CC=C2\C1=C/C1=CN=CN1 VEEGZPWAAPPXRB-BJMVGYQFSA-N 0.000 claims 1
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims 1
- 239000012625 DNA intercalator Substances 0.000 claims 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 229940121369 angiogenesis inhibitor Drugs 0.000 claims 1
- 239000004037 angiogenesis inhibitor Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 239000004310 lactic acid Substances 0.000 claims 1
- 235000014655 lactic acid Nutrition 0.000 claims 1
- 239000001630 malic acid Substances 0.000 claims 1
- 235000011090 malic acid Nutrition 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 235000002906 tartaric acid Nutrition 0.000 claims 1
- 239000011975 tartaric acid Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64280505P | 2005-01-11 | 2005-01-11 | |
| US11/225,565 US8048870B2 (en) | 2005-01-11 | 2005-09-13 | Apoptosis-inducing antineoplastic silver (I) coordination complexes |
| PCT/US2006/000390 WO2006076216A2 (en) | 2005-01-11 | 2006-01-05 | Apoptosis-inducing antineoplastic silver (i) coordination complexes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2008526873A JP2008526873A (ja) | 2008-07-24 |
| JP2008526873A5 true JP2008526873A5 (https=) | 2009-02-19 |
Family
ID=36654047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2007550477A Pending JP2008526873A (ja) | 2005-01-11 | 2006-01-05 | アポトーシス誘発抗腫瘍性銀（ｉ）配位錯体 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8048870B2 (https=) |
| EP (1) | EP1845997A4 (https=) |
| JP (1) | JP2008526873A (https=) |
| CA (1) | CA2593321A1 (https=) |
| WO (1) | WO2006076216A2 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102006049108B4 (de) * | 2006-10-13 | 2019-05-02 | Agxx Intellectual Property Holding Gmbh | Bioaktive, rutheniumhaltige Beschichtungen, deren Verwendung und Verfahren zur Beschichtung einer Vorrichtung |
| EP2167097B1 (en) * | 2007-05-31 | 2014-07-16 | The University of Akron | Metal complexes incorporated within biodegradable nanoparticles and their use |
| WO2009015112A2 (en) * | 2007-07-23 | 2009-01-29 | The University Of Akron | Metal complexes incorporated within biodegradable nanoparticles and their use |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4708864A (en) * | 1984-12-14 | 1987-11-24 | National Research Laboratories | Method and compositions for treating dental structures |
| CH673225A5 (https=) * | 1986-04-22 | 1990-02-28 | Sanosil Ag | |
| CA2070497C (en) * | 1991-06-10 | 1999-05-25 | Go Hata | Novel platinum (ii) complex and antitumor agent |
| JP3595352B2 (ja) | 1993-02-01 | 2004-12-02 | 株式会社サンギ | 抗腫瘍剤及び抗菌剤 |
| US5504055A (en) * | 1994-03-15 | 1996-04-02 | J.H. Biotech, Inc. | Metal amino acid chelate |
| CA2285259A1 (en) * | 1997-03-28 | 1998-10-08 | The Scripps Research Institute | Sandramycin analogs |
| US6280959B1 (en) * | 1997-10-31 | 2001-08-28 | Smithkline Beecham Corporation | Metal complexes |
| BR9915174A (pt) * | 1998-11-09 | 2001-11-06 | Ira Jay Newman | Complexo de prata iÈnica |
| US6242009B1 (en) | 1999-04-20 | 2001-06-05 | Kareem I. Batarseh | Microbicidal formulations and methods to control microorganisms |
| EP1246629A4 (en) * | 2000-01-06 | 2007-04-18 | Marantech Holding Llc | METHODS USING ACTIVE ELECTRON COMPOUNDS FOR MANAGING CANCER CONDITIONS |
| US20040191329A1 (en) * | 2000-07-27 | 2004-09-30 | Burrell Robert E. | Compositions and methods of metal-containing materials |
| US6630172B2 (en) * | 2001-01-22 | 2003-10-07 | Kareem I. Batarseh | Microbicidal composition containing potassium sodium tartrate |
-
2005
- 2005-09-13 US US11/225,565 patent/US8048870B2/en active Active
-
2006
- 2006-01-05 JP JP2007550477A patent/JP2008526873A/ja active Pending
- 2006-01-05 WO PCT/US2006/000390 patent/WO2006076216A2/en not_active Ceased
- 2006-01-05 EP EP06717569A patent/EP1845997A4/en not_active Withdrawn
- 2006-01-05 CA CA002593321A patent/CA2593321A1/en not_active Abandoned
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