JP2008501632A - ガラニン受容体および脳障害 - Google Patents

ガラニン受容体および脳障害 Download PDF

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Publication number
JP2008501632A
JP2008501632A JP2006552676A JP2006552676A JP2008501632A JP 2008501632 A JP2008501632 A JP 2008501632A JP 2006552676 A JP2006552676 A JP 2006552676A JP 2006552676 A JP2006552676 A JP 2006552676A JP 2008501632 A JP2008501632 A JP 2008501632A
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Prior art keywords
galr2
pharmaceutical composition
brain
specific agonist
composition according
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Pending
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JP2006552676A
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English (en)
Japanese (ja)
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JP2008501632A5 (enExample
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ウィニック、デイビッド
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Neurotargets Ltd
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Neurotargets Ltd
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Publication of JP2008501632A publication Critical patent/JP2008501632A/ja
Publication of JP2008501632A5 publication Critical patent/JP2008501632A5/ja
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72Receptors; Cell surface antigens; Cell surface determinants for hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32Alcohol-abuse
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Toxicology (AREA)
  • Addiction (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Psychology (AREA)
  • Zoology (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
JP2006552676A 2004-02-17 2005-01-18 ガラニン受容体および脳障害 Pending JP2008501632A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0403509.3A GB0403509D0 (en) 2004-02-17 2004-02-17 Galanin receptors and brain injury
PCT/GB2005/000188 WO2005080427A1 (en) 2004-02-17 2005-01-18 Galanin receptors and brain injury

Publications (2)

Publication Number Publication Date
JP2008501632A true JP2008501632A (ja) 2008-01-24
JP2008501632A5 JP2008501632A5 (enExample) 2008-03-06

Family

ID=32039889

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2006552676A Pending JP2008501632A (ja) 2004-02-17 2005-01-18 ガラニン受容体および脳障害

Country Status (8)

Country Link
US (2) US20080020975A1 (enExample)
EP (1) EP1723175A1 (enExample)
JP (1) JP2008501632A (enExample)
CN (1) CN1922205A (enExample)
AU (1) AU2005214115B2 (enExample)
CA (1) CA2555550A1 (enExample)
GB (1) GB0403509D0 (enExample)
WO (1) WO2005080427A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017095132A1 (ko) * 2015-11-30 2017-06-08 고려대학교 산학협력단 스펙신 기반 갈라닌 2형 수용체의 효현제 및 이의 용도

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1809619A1 (en) 2004-10-21 2007-07-25 Transtech Pharma, Inc. Bissulfonamide compounds as agonists of galr1, compositions, and methods of use
GB0523550D0 (en) 2005-11-18 2005-12-28 Hunter Fleming Ltd Therapeutic uses of steroidal compounds
AU2008207287A1 (en) * 2007-01-19 2008-07-24 Howard Florey Institute Of Experimental Physiology And Medicine Use of galanin in a method of treating neurodegenerative diseases or conditions
WO2009079078A1 (en) 2007-12-14 2009-06-25 Labogroup S.A.S. Delivering aerosolizable food products
CN108404115A (zh) 2010-10-15 2018-08-17 纽约市哥伦比亚大学理事会 肥胖症-相关的基因和它们的蛋白和其用途
EP2821081A1 (en) * 2013-07-05 2015-01-07 ResuSciTec GmbH Protective solution for preventing or reducing reperfusion injury of the brain and the whole body
KR101514440B1 (ko) * 2013-12-13 2015-04-22 고려대학교 산학협력단 갈라닌 수용체 3형의 리간드로서 스펙신의 용도
US10314911B2 (en) * 2014-04-08 2019-06-11 Healthpartners Research & Education Methods for protecting and treating traumatic brain injury, concussion and brain inflammation with intranasal insulin
CN106880837A (zh) * 2015-12-15 2017-06-23 北京脑重大疾病研究院 一种甘丙肽在制备防止缺血性脑卒的试剂中的应用
ES2707210B2 (es) * 2017-10-02 2020-09-30 Univ Malaga GAL(1-15) y análogos de la misma para uso en la prevención y/o tratamiento de trastornos y efectos relacionados con el alcohol.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2216227A1 (en) * 1996-01-24 1997-07-31 Synaptic Pharmaceutical Corporation Dna encoding galanin galr2 receptors and uses thereof
US5972624A (en) * 1996-01-24 1999-10-26 Synaptic Pharmaceutical Corporation Method of identifying ligands which bind recombinant galanin receptor (GALR2)
EP0918455B1 (en) * 1996-07-24 2003-04-16 Neurotargets Limited Use of galanin to repair nerve damage
WO1998029440A1 (en) * 1996-12-27 1998-07-09 Merck & Co., Inc. Mouse galanin receptor galr2 and nucleotides encoding same
US6337206B1 (en) * 1997-12-18 2002-01-08 Merck & Co., Inc. Nucleic acid encoding mouse galanin receptor (GALR2)
WO2002096934A1 (en) * 2001-05-25 2002-12-05 Kemia, Inc. Non-natural galanin receptor ligands

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
JPN6010067879, HOLMES,F.E. et al, "The distribution of the second galanin receptor (GALR2) protein in mouse brain", Society for Neuroscience Abstracts, 2001, Abstract No.149.8 *
JPN6010067880, LIU,H.X. et al, "Receptor subtype−specific pronociceptive and analgesic actions of galanin in the spinal cord: select", Proc Natl Acad Sci U S A, 2001, Vol.98, No.17, p.9960−4 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017095132A1 (ko) * 2015-11-30 2017-06-08 고려대학교 산학협력단 스펙신 기반 갈라닌 2형 수용체의 효현제 및 이의 용도
JP2018537444A (ja) * 2015-11-30 2018-12-20 ニューラクル サイエンス カンパニー リミテッド スペキシン基盤のガラニン2型受容体のアゴニスト及びその用途
US10385098B2 (en) 2015-11-30 2019-08-20 Neuracle Science Co., Ltd. Agonist of spexin-based galanin type 2 receptor and use thereof
US11248023B2 (en) 2015-11-30 2022-02-15 Neuracle Science Co., Ltd Agonist of spexin-based galanin type 2 receptor and use thereof

Also Published As

Publication number Publication date
US20100184638A1 (en) 2010-07-22
CA2555550A1 (en) 2005-09-01
CN1922205A (zh) 2007-02-28
GB0403509D0 (en) 2004-03-24
US20080020975A1 (en) 2008-01-24
AU2005214115A1 (en) 2005-09-01
WO2005080427A1 (en) 2005-09-01
AU2005214115B2 (en) 2010-08-12
EP1723175A1 (en) 2006-11-22

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