JP2008298481A - Inspection sheet - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide an inspection sheet for widely and accurately inspecting a state of the skin. <P>SOLUTION: The inspection sheet is equipped with a plurality of reagent holding parts containing the same reagent which changes in color by the contact with the secretion produced from the skin and respectively having difference in the change state of a color with respect to the same amount of the secretion. A plurality of the reagent holding parts may be different in the change quantity of the color per a unit time with respect to the same amount of the secretion. Further, a plurality of the reagent holding parts may be respectively different in the change start timing of the color with respect to the same amount of the secretion. <P>COPYRIGHT: (C)2009,JPO&INPIT

Description

  The present invention relates to an inspection sheet. In particular, the present invention relates to an inspection sheet for inspecting the skin condition of a subject.

Patent Document 1 describes a multi-item urine test paper in which a plurality of reagents are each provided with a water-soluble polymer layer, and the time of contact with a specimen is different. Further, Patent Document 2 describes a chemical timer that has an enzyme-containing reagent and reacts with glucose to change the color of the indicator when hydrated.
JP-A-9-96635 Japanese Patent Laid-Open No. 10-142225

  In Patent Document 1 and Patent Document 2, all subjects are tested using the same amount of urine, and the correct color tone is observed at the optimal timing. However, when testing with secretions secreted from the skin of a subject, the amount of secretion per unit time varies from subject to subject, so setting a water-soluble polymer layer for each subject, or testing for each subject It is necessary to set time. For this reason, when all subjects use the same inspection sheet, it is difficult to observe the correct color tone at the optimal timing, and the skin of all subjects having various textures can be observed on the same inspection sheet. It is difficult to observe in detail.

  Then, an object of this invention is to provide the inspection sheet which can solve said subject. This object is achieved by a combination of features described in the independent claims. The dependent claims define further advantageous specific examples of the present invention.

  In order to solve the above-described problem, in the first embodiment of the present invention, the test sheet includes the same reagent whose color changes by contact with the secretion generated from the skin, and the same amount of the secretion. On the other hand, a plurality of reagent holding parts having different color changes are provided.

  The plurality of reagent holding units may have different color changes per unit time for the same amount of secretion. Moreover, the timing at which the color change starts for the plurality of reagent holding units may be different for the same amount of the secretion.

  The above summary of the invention does not enumerate all the necessary features of the present invention, and sub-combinations of these feature groups can also be the invention.

  As is clear from the above description, according to the present invention, the test results can be more accurately shown by the reaction states of the plurality of reagent holders being different from each other.

  Hereinafter, the present invention will be described through embodiments of the invention. However, the following embodiments do not limit the invention according to the scope of claims, and all combinations of features described in the embodiments are included. It is not necessarily essential for the solution of the invention.

  FIG. 1 shows a front view of the inspection sheet 1. The inspection sheet 1 includes a color sample 5, a front sheet 6, a transparent sheet 11, a first reagent holding unit 12, a second reagent holding unit 13, and a third reagent holding unit 14 covered with the transparent sheet 11, respectively. In this embodiment, the case where the test sheet 1 includes three reagent holding units is shown, but the number is not limited as long as a plurality of the test sheet 1 are provided.

  The first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 are provided on the surface of the test sheet 1 that contacts the skin. The transparent sheet 11 has a surface that covers each of the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 and that is in contact with the skin. The front sheet 6 is provided on a surface facing the skin of the transparent sheet 11 with a predetermined color. Further, the front sheet 6 has a through hole at a position where each of the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 can be visually recognized through the transparent sheet 11. The color sample 5 is provided at an arbitrary position on the face of the front sheet 6 that is in contact with the transparent sheet 11. Note that the inspection sheet 1 includes a release sheet on the surface to be adhered to the skin before the inspection is performed. Furthermore, the inspection sheet 1 includes an adhesive layer between the release sheet and the transparent sheet 11.

  The 1st reagent holding part 12, the 2nd reagent holding part 13, and the 3rd reagent holding part 14 contain the same reagent from which a color changes by contacting with the secretions which generate | occur | produce from a subject's skin, respectively. The first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 have different color change states with respect to the same amount of secretion. Each reagent changes color due to the presence of moisture or sebum on the surface of the skin contained in a part of the region where the test sheet 1 is affixed. Specifically, when measuring the moisture of the subject, the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 contain anhydrous cobalt chloride salt as a reagent, and anhydrous cobalt chloride salt The blue color changes to red for cobalt chloride hexahydrate by reacting to the water evaporated from the subject. The reagent may be a pH indicator or the like.

  The first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 have different amounts of color change per unit time for the same amount of secretion. That is, the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 are colored by reacting with secretions at different reaction rates or different reaction start timings from the start of the test. Shows the reaction. Here, the secretion generated from the skin of the subject may be liquid, moisture, oil, sweat, sebum, or the like. The first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14, which have changed color, are compared with the color sample 5 in which a combination of colors exhibited by each color is shown after a certain period of time. The condition of the person's skin is determined. The first reagent holding unit 12, the second reagent holding unit 13, and the third reagent are arranged on the surface where the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 are in contact with the skin. In order to avoid direct contact between the reagent held by the holding unit 14 and the skin, a layer such as a non-woven fabric that transmits moisture or sebum but does not transmit the reagent may be provided.

  The transparent sheet 11 is preferably a resin film having flexibility, excellent transparency, and excellent toughness. Specifically, it may be a polymer resin film, such as polyvinyl chloride, polyvinylidene chloride, polyvinyl alcohol, polyester, polyethylene, polypropylene, polyurethane, polyolefin, and polyamide-based synthetic fiber. The degree of polymerization, the average molecular weight, and the like of the polymer resin film may be appropriately determined according to the usage state of the inspection sheet 1 and the flexibility and durability required for the inspection sheet 1.

  The color sample 5 indicates a combination of colors exhibited by the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 after a predetermined time has elapsed from the start of the test. Further, the color sample 5 indicates an index of the skin state corresponding to the combination of colors exhibited by the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14.

  Further, the inspection system may include an inspection sheet 1, an imaging device 30 that images the inspection sheet 1, and an analysis device 40. The inspection system images the inspection sheet 1 attached to the skin with the imaging device 30 to inspect the skin state.

  First, the test sheet 1 is affixed to the human skin. The reagents held by the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 are moisture or sebum on the surface of the skin included in a part of the region to which the test sheet 1 is attached. Discolors due to existence. The imaging device 30 captures the light transmitted through each of the transparent sheets 11 and transmits captured image data indicating the captured image to the analysis device 40 via the network 50. The analysis device 40 analyzes the skin state from the captured image indicated by the captured image data.

  The imaging device 30 images the inspection sheet 1. The captured image data indicating the captured image captured by the imaging device 30 is transmitted to the analysis device 40 that analyzes the captured image and determines the state of the skin via a network 50 such as a LAN and the Internet. Further, the imaging device 30 may be held in a cradle that can connect the imaging device 30 in an electric communication manner. The cradle is communicably connected to the analysis device 40 via the network 50. In such a case, the imaging device 30 may transmit the captured image data to the analysis device 40 via a cradle.

  The analysis device 40 analyzes the state of the skin from the captured image of the inspection sheet 1 captured by the imaging device 30. The analysis device 40 may be a PC or a server. Specifically, the analysis device 40 acquires the colors exhibited by the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14, respectively, and the combination of these colors and the analysis device 40 The skin state is analyzed from color sample data indicating the skin state corresponding to the combination of colors.

  FIG. 2 shows a front view of the color sample 5. The color swatch 5 indicates the color difference indicated by each of the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 in the column direction after the inspection. Moreover, the color sample 5 shows the color combination which each of the 1st reagent holding | maintenance part 12, the 2nd reagent holding | maintenance part 13, and the 3rd reagent holding | maintenance part 14 shows after a test | inspection in a row direction. Furthermore, the color sample 5 is a combination of the colors indicated by the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14, that is, the state of the subject's skin according to the row direction. The indicator of The color exhibited by each of the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14, and the first reagent holding unit 12, the second reagent holding unit 13, and the third color sample 5 indicate. The state of the skin is determined from the color combination of the reagent holding unit 14.

  FIG. 3 shows a first embodiment of a side sectional view of the inspection sheet 1. The inspection sheet 1 includes a color sample 5, a front sheet 6, a first transmission part 7, a second transmission part 8, a third transmission part 9, an adhesive layer 10, a transparent sheet 11, a first reagent holding part 12, and a second reagent holding. Unit 13 and third reagent holding unit 14.

  The first transmission part 7, the second transmission part 8, and the third transmission part 9 are provided at positions that contact the skin of the test sheet 1, respectively. And the 1st permeation | transmission part 7, the 2nd permeation | transmission part 8, and the 3rd permeation | transmission part 9 are adjacent to the surface facing the skin of the 1st reagent holding part 12, the 2nd reagent holding part 13, and the 3rd reagent holding part 14. Are provided, and pass through the secretions. The first reagent holding unit 12 is disposed in contact with the upper surface of the first transmission unit 7, that is, the surface opposite to the surface of the first transmission unit 7 that contacts the skin. The second reagent holding unit 13 is arranged in contact with the upper surface of the second transmission unit 8, that is, the surface opposite to the surface of the second transmission unit 8 that contacts the skin. The third reagent holding unit 14 is disposed in contact with the upper surface of the third transmission unit 9, that is, the surface opposite to the surface of the third transmission unit 9 that contacts the skin. In addition, the 1st permeation | transmission part 7, the 2nd permeation | transmission part 8, and the 3rd permeation | transmission part 9 are formed with porous materials, such as acetylcellulose, a polysulfone, a nitrocellulose, and a polyvinylidene chloride.

  The transparent sheet 11 is arranged in contact with the upper surfaces of the first transmission part 7, the second transmission part 8, and the third transmission part 9. The transparent sheet 11 covers the first transmission part 7, the second transmission part 8, and the third transmission part 9, as well as the first reagent holding part 12, the second reagent holding part 13, and the third reagent holding part 14. The adhesive layer 10 is provided on the lower surface of the transparent sheet 11, that is, the surface of the transparent sheet 11 that faces the skin. In addition, the adhesion layer 10 may be an acrylic adhesive, for example.

  The front sheet 6 is disposed in contact with the upper surface of the transparent sheet 11, that is, the surface opposite to the surface in contact with the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14. The front sheet 6 has through holes at positions where the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 can be visually recognized through the transparent sheet 11. The color sample 5 is provided on the surface of the front sheet 6 opposite to the surface that contacts the transparent sheet 11.

  The first permeation unit 7 has a plurality of through holes that penetrate from the skin to the first reagent holding unit 12. The 2nd permeation | transmission part 8 has a some through-hole penetrated to the 2nd reagent holding | maintenance part 13 from skin. The third permeable part 9 has a plurality of through holes that penetrate from the skin to the third reagent holding part 14. The plurality of through holes included in each of the first transmission unit 7, the second transmission unit 8, and the third transmission unit 9 have different sizes for each transmission unit. For example, the 1st permeation | transmission part 7, the 2nd permeation | transmission part 8, and the 3rd permeation | transmission part 9 shall have a through-hole of a large, medium, and small magnitude | size, respectively. That is, the first permeation unit 7 permeates a large amount of secretions to the first reagent holding unit 12 with respect to the transpiration amount of the secretion secreted from a certain skin. Further, the second permeation unit 8 permeates the medium secretion to the second reagent holding unit 13. Further, the third permeation part permeates a small amount of secretions to the third reagent holding part 14.

  Each of the first transmission part 7, the second transmission part 8, and the third transmission part 9 includes through-holes having different sizes for each transmission part. The amounts of secretions that reach the reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 are different. In addition, each of the 1st permeation | transmission part 7, the 2nd permeation | transmission part 8, and the 3rd permeation | transmission part 9 may have the through-hole of the same magnitude | size from which the number per unit area differs for every permeation | transmission part. . After a lapse of a certain time from the start of the test, the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 are different from each other in the amount of secretion that permeates from the permeation unit in contact with each other. Each shows a different amount of color change.

  FIG. 4 shows changes in the color of the reagent holding unit according to the first embodiment of the present invention. In FIG. 4, the vertical axis represents the amount of change in color of each reagent holding portion, and the horizontal axis represents the transpiration amount of the secretion secreted from the skin. A change amount of the color of the first reagent holding unit 12 with respect to the transpiration amount of the secretion from the skin is shown in a. The amount of change in the color of the second reagent holding unit 13 with respect to the amount of transpiration from the skin is shown in b. The amount of change in the color of the third reagent holding unit 14 with respect to the amount of transpiration of the secretion from the skin is shown in c. The color change amount includes, in addition to the hue change amount, an amount that the color becomes darker and an amount that the color becomes lighter. Further, the speed at which the color of each reagent holder changes with respect to the amount of transpiration is represented by the slopes of a, b, and c.

  When the transpiration amount of the secretion from the skin after a lapse of a certain time from the start of the test is k, the first reagent holding unit 12 shows a state where the color has already sufficiently changed due to the reaction of many reagents. The second reagent holding unit 13 shows a state in which more than half of the reagent has changed while the color change is in progress. The third reagent holding unit 14 shows a state in which about half of the reagent has changed while the color change is in progress. As described above, the reagents included in each of the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 change in color at different reaction rates.

  By differentiating the reaction rates of the reagents included in each of the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14, it is possible to accurately match the case where there is one reagent holding unit. Can examine skin condition. Furthermore, various skin conditions can be examined more widely. For example, even when the skin is dry and the skin where the amount of transpiration of the secretion is extremely small is examined, the color of the reagent included in the first reagent holding unit 12 changes greatly. Therefore, the amount of transpiration of dry skin can be accurately inspected. Further, even when the skin is well moistened and the skin where the amount of transpiration of the secretion is extremely large is examined, the color of the reagent included in the third reagent holding unit 14 continues to change without being saturated. Therefore, the amount of transpiration of well moistened skin can be accurately inspected. Therefore, various skin conditions can be inspected with one inspection sheet 1.

  FIG. 5 shows a second embodiment of a side sectional view of the inspection sheet 1. The test sheet 1 includes a color sample 5, a front sheet 6, an adhesive layer 10, a transparent sheet 11, a first reagent holding unit 12, a second reagent holding unit 13, a third reagent holding unit 14, a first permeation unit 24, and a second. A transmission part 25 and a third transmission part 26 are provided.

  In addition, the inspection sheet 1 according to the present embodiment includes the first transmission part 24, the second transmission part 25, and the third transmission part 26 shown in FIGS. 1 to 4 except that each has a transmission layer and an absorbent material. It has substantially the same function and configuration as the inspection sheet 1 in the above description. Therefore, in the following description, detailed description of the other components excluding the first transmission part 24, the second transmission part 25, and the third transmission part 26 is omitted.

  The first permeation unit 24 is provided adjacent to the surface of the first reagent holding unit 12 that faces the skin. The first transmission part 24 includes the first transmission layer 15 and the first absorbent material 18. The first transmission layer 15 is provided on the surface of the first transmission part 24 that contacts the skin. The first absorbent material 18 is provided on the surface of the first permeation unit 24 that contacts the first reagent holding unit 12.

  The 2nd permeation | transmission part 25 is provided adjacent to the surface facing the skin of the 2nd reagent holding | maintenance part 13. FIG. The second transmission part 25 includes the second transmission layer 16 and the second absorbent material 19. The second transmission layer 16 is provided on the surface of the second transmission part 25 that comes into contact with the skin. The second absorbent material 19 is provided on the surface of the second permeation unit 25 that contacts the second reagent holding unit 13.

  The third permeation part 26 is provided adjacent to the surface of the third reagent holding part 14 facing the skin. The third transmission part 26 includes the third transmission layer 17 and the third absorbent material 20. The third transmission layer 17 is provided on the surface of the third transmission part 26 that contacts the skin. The third absorbent material 20 is provided on the surface of the third permeation portion 26 that contacts the third reagent holding portion 14.

  The first permeable layer 15, the second permeable layer 16, and the third permeable layer 17 each transfer the same amount of secretion from the skin to the first absorbent material 18, the second absorbent material 19, and the third absorbent material 20. And infiltrate. The first absorbent material 18, the second absorbent material 19, and the third absorbent material 20 are placed on the skin before the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14, respectively. Absorbs secretions from Specifically, when examining moisture in the skin using cobalt chloride as a reagent, the first absorbent material 18, the second absorbent material 19, and the third absorbent material 20 use a moisture absorbing member such as silica gel or zeolite. The first absorbent material 18, the second absorbent material 19, and the third absorbent material 20 absorb the secretion from the skin sufficiently, and then the first reagent holding part 12, the second reagent holding part 13, and the third reagent holding part. 14 infiltrate the secretions from the skin.

  The 1st absorption material 18, the 2nd absorption material 19, and the 3rd absorption material 20 are designed so that the absorption amount of a secretion may differ, respectively. That is, the first absorbent material 18, the second absorbent material 19, and the third absorbent material 20 have different thicknesses or different members, and become saturated at different times. As a result, the first absorbent material 18, the second absorbent material 19, and the third absorbent material 20 are transferred to the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 at different times. And let the secretions reach. The first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 react with the secretion at different timings and change color with respect to the same amount of the secretion. Note that any one of the first absorbent material 18, the second absorbent material 19, and the third absorbent material 20 may have a structure that does not absorb secretions. That is, assuming that the first absorbent material 18 has a structure that does not absorb secretions, the first absorption material 18 passes through the secretions that have permeated the first permeable layer 15 as it is to the first reagent holding unit 12. To reach. In this case, the first reagent holding unit 12 starts the color change due to the secretion from the start of the test. In the present embodiment, the first absorbent material 18 has a structure that does not absorb secretions, and the case where the second absorbent material 19 is small and the third absorbent material has a large amount of secretions will be described.

  FIG. 6 shows the color change of the reagent holding part according to the second embodiment of the present invention. In FIG. 6, the vertical axis represents the amount of change in color of each reagent holding portion, and the horizontal axis represents the transpiration amount of the secretion secreted from the skin. A change amount of the color of the first reagent holding unit 12 with respect to the transpiration amount of the secretion from the skin is shown in a. The amount of change in the color of the second reagent holding unit 13 with respect to the amount of transpiration from the skin is shown in b. The amount of change in the color of the third reagent holding unit 14 with respect to the amount of transpiration of the secretion from the skin is shown in c. The color change amount includes, in addition to the hue change amount, an amount that the color becomes darker and an amount that the color becomes lighter. Further, the speed at which the color of each reagent holder changes with respect to the amount of transpiration is represented by the slopes of a, b, and c.

When starting the test, the first reagent holding portion 12, transpiration of secretions and color change until l _1, color change ends at transpiration rate l _1. Second reagent holding portion 13, transpiration of secretions from the skin when reached l _1, to initiate the reaction with the secretions from the skin. The second reagent holding unit 13 starts the reaction when the secretion from the skin reaches the transpiration amount l ₁ , and the color change ends at the transpiration amount l ₂ . The third reagent holder 14, transpiration of secretions from the skin when reached l _2, to initiate the reaction with the secretions from the skin. The third reagent holder 14, secretions from the skin starts to react when it reaches the transpiration rate l _2, and a color change to a transpiration l _3, color change ends at transpiration l ₃ To do.

  When the amount of transpiration of the secretion from the skin after a lapse of a certain time from the start of the test is k, the first reagent holding unit 12 and the second reagent holding unit 13 are already sufficiently colored due to the reaction of many reagents. Indicates a changing state. The third reagent holding unit 14 shows a state in which about ¼ of the reagent has changed while the color change is in progress. Thus, each reagent holding part reacts sequentially according to the amount of transpiration.

Since each of the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 sequentially reacts, a subject with extremely high water content or a subject with extremely low water content In both cases, accurate inspection can be performed at the same time. Further, since each of the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 reacts separately, it is possible to inspect for a long time without increasing the thickness of the inspection sheet 1. . That is, it is possible to transpiration secretions are examined until a l _3.

  FIG. 7 shows another example of the color change of the reagent holding unit according to the second embodiment of the present invention. In FIG. 7, the vertical axis indicates the amount of change in color of each reagent holding portion, and the horizontal axis indicates the transpiration amount of the secretion secreted from the skin. A change amount of the color of the first reagent holding unit 12 with respect to the transpiration amount of the secretion from the skin is shown in a. The amount of change in the color of the second reagent holding unit 13 with respect to the amount of transpiration from the skin is shown in b. The amount of change in the color of the third reagent holding unit 14 with respect to the amount of transpiration of the secretion from the skin is shown in c. The color change amount includes, in addition to the hue change amount, an amount that the color becomes darker and an amount that the color becomes lighter. Further, the speed at which the color of each reagent holder changes with respect to the amount of transpiration is represented by the slopes of a, b, and c.

  When the amount of transpiration of the secreted substance after the elapse of a certain time from the start of the test is k, the first reagent holding unit 12 shows a state where the color has already sufficiently changed due to the reaction of many reagents. The second reagent holding unit 13 shows a state in which about 2/3 of the reagent has changed while the color change is in progress. Further, the third reagent holding unit 14 shows a state in which about 1/3 of the reagent has changed while the color change is in progress. As described above, the reagent included in each of the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 starts changing at different timings and changes color at the same speed.

  By providing a plurality of reagent holders and changing the color change start timing for the reagents contained in each reagent holder, it is possible to accurately inspect the skin condition when there is only one reagent holder. . Furthermore, since the test sheet 1 includes a plurality of reagent holders, various skin conditions can be examined more widely. For example, when the skin is dried and the skin where the amount of transpiration of the secretion is extremely small is examined, the reagent included in the first reagent holding unit 12 starts to change with respect to the amount of transpiration. In addition, when the skin is well moistened and the skin where the amount of transpiration of the secretion is extremely large is examined, the color of the reagent included in the third reagent holding unit 14 changes at a late start timing with respect to the large amount of transpiration. Start. Therefore, it is possible to inspect subjects having various skin conditions with one inspection sheet 1.

  Since the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 are color-reacted at different reaction timings and color-reacted with secretions at the same speed, the reagent holding unit is For a single case, the skin condition can be accurately checked. Furthermore, various skin conditions can be examined more widely. That is, since the first reagent holding unit 12, the second reagent holding unit 13, and the third reagent holding unit 14 show different colors with respect to the skin state, the accurate skin state can be inspected, It is possible to examine a wide range of skin with high moisture and low moisture. Furthermore, the 1st absorption material 18, the 2nd absorption material 19, and the 3rd absorption material 20 have the absorption amount of a different secretion, respectively, The 1st reagent holding | maintenance part 12 and the 2nd reagent which each respond | correspond Each color reaction start timing of the holding unit 13 and the third reagent holding unit 14 can be controlled.

  FIG. 8 shows a third embodiment of a side sectional view of the inspection sheet 1. The test sheet 1 includes a color sample 5, a front sheet 6, an adhesive layer 10, a transparent sheet 11, a first reagent holding unit 21, a second reagent holding unit 22, a third reagent holding unit 23, a first transmission unit 27, and a second. A transmission part 28 and a third transmission part 29 are provided.

  Note that the test sheet 1 according to the present embodiment is different from the first reagent holding unit 21, the second reagent holding unit 22, and the third reagent holding unit 23 in that the concentrations of the reagents are different from each other, Except that the second transmission part 28 and the third transmission part 29 have the same penetration amount, the second transmission part 28 and the third transmission part 29 have substantially the same function and configuration as the inspection sheet 1 in the above description of FIGS. The first transmission part 27, the second transmission part 28, and the third transmission part 29 are substantially the same as the first transmission layer 15, the second transmission layer 16, and the third transmission layer 17 in FIGS. Has function and configuration. Therefore, in the following description, detailed description of the other components except the first reagent holding unit 21, the second reagent holding unit 22, and the third reagent holding unit 23 is omitted.

  The first reagent holding unit 21 is provided on the upper surface of the first permeation unit 27, that is, the surface opposite to the surface in contact with the skin. The second reagent holding unit 22 is provided on the upper surface of the second permeation unit 28, that is, the surface opposite to the surface in contact with the skin. The third reagent holding unit 23 is provided on the upper surface of the third permeation unit 29, that is, the surface opposite to the surface in contact with the skin.

  Moreover, the 1st reagent holding | maintenance part 21, the 2nd reagent holding | maintenance part 22, and the 3rd reagent holding | maintenance part 23 contain the reagent of a respectively different density | concentration. The amount of reagent contained in each reagent holding unit can be realized by varying the amount of reagent per unit area or the amount of reagent per unit volume. In the present embodiment, the first reagent holding unit 21, the second reagent holding unit 22, and the third reagent holding unit 23 include thin, intermediate, and high concentration reagents, respectively.

  FIG. 9 shows the color change of the reagent holding part according to the third embodiment of the present invention. In FIG. 9, the vertical axis indicates the amount of change in the color of each reagent holding portion, and the horizontal axis indicates the transpiration amount of the secretion secreted from the skin. The amount of change in the color of the first reagent holding portion 21 with respect to the amount of transpiration of the secretion from the skin is shown in a. The amount of change in the color of the second reagent holding unit 22 with respect to the amount of transpiration of the secretion from the skin is shown in b. The amount of change in the color of the third reagent holding unit 23 relative to the amount of transpiration of the secretion from the skin is shown in c. The color change amount includes, in addition to the hue change amount, an amount that the color becomes darker and an amount that the color becomes lighter. Further, the speed at which the color of each reagent holder changes with respect to the amount of transpiration is represented by the slopes of a, b, and c.

  When the transpiration amount of the secretion from the skin after a lapse of a certain time from the start of the test is k, the first reagent holding unit 21 shows a state where the color has already sufficiently changed due to the reaction of many reagents. The second reagent holding unit 22 shows a state in which 4/5 of the reagent has changed while the color change is in progress. The third reagent holding unit 23 shows a state in which about half of the reagent has changed while the color change is in progress. As described above, the reagents contained in the respective reagent holding units complete the reaction with different transpiration amounts.

  The first reagent holding unit 21, the second reagent holding unit 22, and the third reagent holding unit 23 include different concentrations of reagents, so that different colors are obtained after a predetermined time has elapsed since the start of the reagent test. Presents. That is, color differences occur in the first reagent holding unit 21, the second reagent holding unit 22, and the third reagent holding unit 23. The difference in color makes it easy to see the difference in color reaction among the first reagent holding unit 21, the second reagent holding unit 22, and the third reagent holding unit 23, so that an accurate skin condition can be inspected.

The front view of the test | inspection sheet 1 is shown. The front view of the color sample 5 is shown. 1st embodiment of the side sectional view of the test | inspection sheet 1 is shown. The change of the color of the reagent holding part which concerns on 1st embodiment of this invention is shown. 2nd embodiment of the side sectional view of the test | inspection sheet 1 is shown. The change of the color of the reagent holding part which concerns on 2nd embodiment of this invention is shown. The another example in the change of the color of the reagent holding part which concerns on 2nd embodiment of this invention is shown. 3rd embodiment of the side sectional view of the test | inspection sheet 1 is shown. The change of the color of the reagent holding part which concerns on 3rd embodiment of this invention is shown.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 Test sheet 5 Color sample 6 Table sheet 7 1st permeation | transmission part 8 2nd permeation | transmission part 9 3rd permeation | transmission part 10 Adhesive layer 11 Transparent sheet 12 1st reagent holding | maintenance part 13 2nd reagent holding | maintenance part 14 3rd reagent holding | maintenance part 15 1st One permeable layer 16 Second permeable layer 17 Third permeable layer 18 First absorbent material 19 Second absorbent material 20 Third absorbent material 21 First reagent holding part 22 Second reagent holding part 23 Third reagent holding part 24 First permeation Part 25 Second transmission part 26 Third transmission part 27 First transmission part 28 Second transmission part 29 Third transmission part

Claims (9)

A test sheet comprising a plurality of reagent holders each containing the same reagent that changes color by contact with secretions generated from the skin and having different color change states for the same amount of the secretions.   2. The test sheet according to claim 1, wherein the plurality of reagent holding units have different amounts of color change per unit time with respect to the same amount of the secretion. Each of the plurality of reagent holding portions is provided adjacent to a surface facing the skin, and further includes a plurality of permeation portions that respectively permeate the secretions.
The test sheet according to claim 2, wherein the plurality of permeation units have different amounts of the secretions that reach each of the plurality of reagent holding units from the skin per unit time. The plurality of permeation portions have through holes penetrating from the skin to each of the plurality of reagent holding portions,
The inspection sheet according to claim 3, wherein each of the plurality of transmission parts has different sizes of the through holes. The plurality of permeation portions have through holes penetrating from the skin to each of the plurality of reagent holding portions,
The inspection sheet according to claim 3, wherein the number of the through holes that each of the plurality of transmission portions has per unit area is different.   The test sheet according to claim 1, wherein the plurality of reagent holding units have different timings at which a color change starts for the same amount of the secretion. Each of the plurality of reagent holding portions is provided adjacent to a surface facing the skin, and further includes a plurality of permeation portions that respectively permeate the secretions.
The test sheet according to claim 6, wherein the plurality of permeation units have different times until the secretions reach each of the plurality of reagent holding units.   The test sheet according to claim 7, wherein the plurality of transmission parts include a material that absorbs the secretion, and the amount of absorption of the secretion is different.   The test sheet according to claim 1, wherein the concentrations of the reagents included in the plurality of reagent holding units are different from each other.

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