JP2008184203A - Medical lid material - Google Patents

Abstract

<P>PROBLEM TO BE SOLVED: To provide a medical lid material which has sterilizability and sterility after sterilization and is not costly and is free from paper peeling as a lid material having the ventilation property of a polyolefin molded container that stores medical appliances or the like. <P>SOLUTION: An anchor coating agent layer mainly composed of a polyester resin is provided between a paper layer 10 of impregnated paper or the like and a heat seal agent layer 11 mainly composed of an ethylene-vinylacetate copolymer. In the medical lid material 1, the heat seal agent layer and the anchor coating agent layer are formed through the gravure roll coating of varnish which has a solid component of 5-50% and a viscosity of 10-40 seconds on a #3 Zahn cup by a Zahn cup viscometer, and the gas permeability indicating gas permeation property is not lower than 30 seconds/100 cc and not higher than 2000 seconds/100 cc in a testing method using a B type measuring device according to JIS P8117. <P>COPYRIGHT: (C)2008,JPO&INPIT

Description

  TECHNICAL FIELD The present invention relates to a breathable lid member having an easy peel property (easy peel openability) using a paper layer as a base material, and in particular, a molded container made of a polyolefin-based resin for storing medical instruments and the like. As a lid material, both medical sterilization by gas permeation and sterilization after sterilization are achieved, and it can be easily peel-opened (peeled and unsealed) with little force. It is about.

  Conventionally, as a lid that can be easily peel-opened (peeled and opened) for molded containers made of polyolefin resin, a hot-melt agent is applied to the inner surface of the paper substrate as a heat seal agent, or a solvent-based heat There were methods of using a seal lacquer or laminating an easy peel film. However, when this lid material is used in a molded container made of polyolefin resin for storing medical devices, etc., it is used for EOG sterilization frequently used in the sterilization method, or by other sterilization methods such as γ-ray sterilization. In order to allow the volatile gas generated from the bonding resin part of the medical device to permeate, the lid material requires a certain level of gas permeability, and even if the gas permeates too much, bacteria and insects from outside tend to enter. It was a problem.

  As described above, the above-mentioned easy peel film having almost no gas permeability is used as the heat sealing agent applied to the inner surface thereof as a medical lid material that achieves both sterility by gas permeability and maintenance of sterility after sterilization. It is impossible.

  Moreover, as a medical lid material as described above, there is an example of using the above heat seal lacquer or hot melt agent as the heat seal agent, and paper that guarantees sterility with gas permeability of the paper itself, for example, a special type Impregnated paper marketed by paper manufacturers: The inner surface of S-Belan NF is coated with a polyolefin heat seal lacquer, or the inner surface of a paper layer is coated with a hot melt agent mainly composed of an ethylene-vinyl acetate copolymer. There exists a structure (for example, refer patent document 1).

  However, with the above structure, there is moderate gas permeability, and both sterilization and sterility after sterilization are compatible. However, the cover material is peeled off during use (peeling and opening), and the take-out part (opening) is removed. There was a complaint from the user that it became difficult to take out by covering or paper remained in the opening. Furthermore, the contents that had been maintained sterility could be contaminated by performing the work of removing the remaining paper-peeled portion again.

  Furthermore, there is a configuration in which the above heat-seal lacquer is coated on a high-density polyethylene non-woven fabric (Tyvek) marketed by Asahi DuPont Flash Spun Products. In addition, there has been a problem that fibrous flaking caused by the nonwoven fabric occurs after peeling.

The above prior art documents are shown below.
Japanese Patent Laid-Open No. 9-238837

The present invention solves the problems of the prior art, and the problem is that
As a breathable lid for molded containers made of polyolefin resin that stores medical instruments and materials, etc., medical use that maintains sterility and sterility after sterilization, and does not cost much and does not peel off paper It is to provide a lid.

  In order to achieve the above object in the present invention, first, in the invention of claim 1, heat sealing is performed on the opening of the container body made of a polyolefin resin containing medical instruments and materials, and the paper layer is used as a base. A gas-permeable medical lid material having at least a heat sealant layer laminated on one side thereof, wherein the heat sealant layer is mainly composed of an ethylene vinyl acetate copolymer, and the heat sealant layer and the base material An anchor coating agent layer mainly composed of a polyester-based resin is applied between the heat sealing agent layer and the anchor coating agent layer at a solid content of 5 to 50%, and the viscosity by the Zahn cup viscometer is Zahn cup #. No. 3, a varnish for 10 to 40 seconds is formed by gravure roll coating, which is a medical lid material.

  In the invention of claim 2, the air permeability representing the air permeability is 30 seconds / 100 cc or more and 2000 seconds / 100 cc or less by a test method using a B-type measuring instrument in accordance with JIS P8117. The medical lid material according to claim 1.

  The invention according to claim 3 is the medical lid material according to claim 1 or 2, wherein the heat sealant layer contains a modified polyolefin.

  Furthermore, in the invention of claim 4, the paper layer as the base material is impregnated paper in which paper is impregnated with an acrylic resin, and the medical use according to any one of claims 1 to 3 It is a lid material.

  Since this invention is the above structure, there exist the following effects.

  That is, according to the invention according to claim 1, in the air-permeable medical lid material in which the paper layer is a base material and at least the heat sealant layer is laminated on one side thereof, the base material, the heat sealant layer, By providing a polyester-based resin to the anchor coat layer applied between, heat resistance is imparted to this anchor coat layer, preventing penetration of the heat seal layer into the paper layer during thermal welding with a polyolefin-based container, Delamination can be performed stably. By using delamination in this way, instability of peel strength due to temperature during sealing is eliminated, and stable peel strength can be obtained in a wide heat seal area. In addition, it can be a medical cover material without paper peeling.

  Furthermore, according to the invention according to claim 1, the heat sealant layer and the anchor coat agent layer have a solid content of 5 to 50%, and the viscosity according to the Zahn cup viscometer is 10 to 40 seconds in Zahn cup # 3. By forming the varnish with gravure roll coating, productivity can be improved and the thickness and shape of the plate used for gravure roll coating can be controlled, that is, the air permeability can be controlled. It can be set as the medical cover material which enables control.

  According to the invention of claim 2, the air permeability representing air permeability is 30 seconds / 100 cc or more and 2000 seconds / 100 cc or less in a test method using a B-type measuring device compliant with JIS P8117. By doing so, it is possible to provide a medical lid material that achieves both sterility and sterility after sterilization. Thus, if the air permeability by the above measurement method is less than 30 seconds / 100 cc, the gas permeability is poor and the sterilization is lost, and if it exceeds 2000 seconds / 100 cc, sterility after sterilization cannot be maintained, which is not preferable. .

  In addition, according to the invention according to claim 3, the heat sealing agent layer includes a modified polyolefin, thereby improving welding by heat sealing with a molded container body made of polyolefin (polyethylene, polypropylene) resin. Thus, the medical lid can be more stably peeled between the anchor coat layer.

  Furthermore, according to the invention according to claim 4, the conventional high density polyethylene nonwoven fabric or the like is used by making the paper layer as the base material impregnated paper in which the paper is impregnated with acrylic resin. Compared with this, the cost can be increased and the interlaminar strength of the paper layer can be greatly improved, so that the medical lid can be more easily prevented from being peeled off or torn.

  Therefore, the present invention exerts an excellent practical effect as a lid for a plastic container that accommodates medical instruments, materials, and the like in which both sterilization and sterility after sterilization are compatible.

  Hereinafter, the best mode for carrying out the present invention will be described with reference to the drawings.

  FIG. 1 is a cross-sectional view of a medical lid 1 of the present invention, and the configuration thereof is a configuration in which an anchor coat agent layer 12 and a heat seal agent layer 11 are sequentially laminated on one side of a paper layer 10. FIG. 2 is an external cross-sectional view of a medical molded container 5 in which the medical lid material 1 of the present invention is provided on the molded container main body 2 for storing the contents 3 such as medical instruments.

The paper layer 10 shown in FIG. 1 is not particularly limited as long as the marketed paper itself guarantees sterility, and for example, any of high-quality paper, coated paper, impregnated paper, etc. is used. Of these, impregnated paper having a high interlayer strength among the paper layers can be more preferably used. These basis weight is desirably ² to 100 g / m ² approximately 30 g / m due to the need for some degree of stiffness as a lid.

  The anchor coating agent layer 12 is not particularly limited as long as it is an anchor coating agent for gravure roll coating mainly composed of a polyester-based resin that is marketed, and the solid content is 20% to 40%. It is more desirable considering long run production.

  In addition, as the heat sealant layer 11, if it is a heat seal lacquer for gravure roll coating mainly composed of commercially available ethylene-vinyl acetate copolymer (EVA), a lacquer agent or emulsion diluted with a solvent There is no particular restriction on the type. Furthermore, when the container main body 2 which is the adherend shown in FIG. 2 is a polyolefin-based container, the close contact with the container main body 2 which is the adherend is improved by containing the modified polyolefin in the heat sealant layer 11, and more Stable peel strength can be obtained.

  Specific examples of the present invention will be described below.

As the paper layer, impregnated paper having a basis weight of 95 g / m ² : S Belan NF (manufactured by Tokushu Paper Industries Co., Ltd.) was used. As an anchor coating agent layer on one side, an anchor having a solid content of 26% and a Zahn cup # 3 viscosity of 18 seconds was used. Coating varnish: PS008HS (manufactured by Toyo Ink Mfg. Co., Ltd.) is applied by a gravure roll coating method to form an anchor coating agent layer having a dry coating amount of 5 g / m ² , and a solid content as a heat sealant layer thereon. Apply heat seal lacquer: M-720AH (manufactured by Dainippon Ink & Chemicals, Inc.) with 25% Zahn cup # 3 and a viscosity of 26 seconds by a gravure roll coat method, and a heat sealant layer with a dry coating amount of 5 g / m ^2. This was formed to obtain a medical lid.

A medical lid was obtained in the same manner as in Example 1 except that high-quality paper having a basis weight of 64 g / m ² : KFD-DF (manufactured by Nippon Paper Industries Co., Ltd.) was used as the paper layer.

  Examples for comparison with the present invention will be described below.

  A comparative medical lid was obtained in the same manner as in Example 1 except that the anchor coating agent layer was not applied between the paper layer and the heat sealant layer.

  A comparative medical lid was obtained in the same manner as in Example 2 except that the anchor coating agent layer was not applied between the paper layer and the heat sealant layer.

Using the medical lid material of Examples 1 to 4 above, heat sealing was performed on the polypropylene (PP) -based molded container under the following conditions, and the peeling evaluation of the medical lid material was performed by the number of occurrences of paper peeling by a monitor. The results are shown in Table 1.
[Heat seal conditions]
Condition 1: Sealing temperature: 170 ° C., sealing time: 0.5 sec × 2 times, sealing pressure: 14.7 N / cm ²
Condition 2: Sealing temperature: 230 ° C., sealing time: 0.5 seconds × twice, sealing pressure: 14.7 N / cm ²
・ Number of paper peeling: Number of occurrences / number of measurements

上記表１の実施例１と比較のための実施例３の結果から、ポリエステル系アンカーコート剤は紙剥けの減少に大きな効果があり、更には実施例１と２の比較から含浸紙が紙剥けの減少には大きな効果があった。実施例２のように紙層強度の弱い上質紙を用いても、シール条件においては紙剥けが発生し難いことが確認できた。

From the results of Example 1 for comparison with Example 1 in Table 1 above, the polyester-based anchor coating agent has a great effect in reducing paper peeling. Further, from the comparison of Examples 1 and 2, the impregnated paper is peeled off. There was a big effect on the decrease of. Even when high-quality paper having a weak paper layer strength as in Example 2 was used, it was confirmed that paper peeling hardly occurred under the sealing conditions.

In addition, using the medical lid materials of Examples 1 to 4, the polypropylene (PP) -based molded container was heat-sealed under the above conditions, and the peel strength was measured under the following conditions using a tensile tester. . Furthermore, the cross-section observation of the lid | cover material after peeling was implemented, the peeling interface was identified, and the result was shown in Table 2.
[Peel strength (tensile testing machine) conditions]
・ Peeling speed: 300 mm / min,
・ Peeling angle: 180 degrees [state of peeling interface]
Measuring instrument: optical microscope; BHSM (manufactured by Olympus Optical Co., Ltd.)
: Scanning electron microscope; S-4800 (manufactured by Hitachi, Ltd.)

上記表２から実施例１、２と比較のための実施例３、４とでは、アンカーコート剤層を施すことによる剥離界面の差異が極鮮明に見られた。

From Table 2 above, in Examples 1 and 2 for comparison and in Examples 3 and 4 for comparison, the difference in the peeling interface due to the application of the anchor coating agent layer was clearly seen.

It is explanatory drawing which represented one Embodiment of the medical cover material of this invention with the side cross section. It is explanatory drawing which represented one Embodiment of the shaping | molding container which accommodates the medical instrument etc. which used the medical cover material of this invention by the side cross section.

Explanation of symbols

DESCRIPTION OF SYMBOLS 1 ... Medical cover material 2 ... Molded container main body 3 ... Contents 5 ... Medical molded container 10 ... Paper layer 11 ... Heat seal agent layer 12 ... Anchor coat agent layer

Claims (4)

  Air-permeable medical use that is heat-sealed at the opening of a container body made of polyolefin resin that contains medical instruments and materials, and has a paper layer as a base material and at least a heat-sealant layer laminated on one side In the lid material, the heat sealant layer is mainly composed of an ethylene vinyl acetate copolymer, and an anchor coat agent layer mainly composed of a polyester resin is applied between the heat sealant layer and the base material, The heat sealant layer and the anchor coat agent layer have a solid content of 5 to 50%, and a varnish of 10 to 40 seconds is formed by gravure roll coating in a Zahn cup viscometer with a Zahn cup viscometer. Medical cover material.   2. The medical use according to claim 1, wherein the air permeability representing the air permeability is 30 seconds / 100 cc or more and 2000 seconds / 100 cc or less by a test method using a B-type measuring instrument in accordance with JIS P8117. Lid material.   The medical lid material according to claim 1 or 2, wherein the heat sealant layer contains a modified polyolefin.   The medical lid according to any one of claims 1 to 3, wherein the paper layer as the base material is impregnated paper in which paper is impregnated with an acrylic resin.

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